PUBLICATIONS

  1. Rogers GB and Bruce KD Exploring the parallel development of microbial systems in cystic fibrosis neonates – a commentary. Mbio (in press)
  2. Wiriyachaiporn S, Howarth P, Bruce KD, Dailey LA Clinical evaluation of a rapid lateral flow immunoassay for Staphylococcus aureus detection in respiratory samplesDiagnostic Microbiology and Infectious Disease(in press)
  3. Rogers GB,Hoffman LR, Cutherbertson L, WingP, Pope C, Hooftman D, Lilley AK, Carroll MP, Bruce KD,van der Gast CJ. Towards unbiased bacterial community analysis in lower respiratory infections. ISME J. (in press)
  4. Chung J, Becq J, Fraser L, Schulz-Trieglaff O, Bond N, Foweraker J, Bruce K, Smith G, Welch M (2012) Genomic variation among contemporary Pseudomonas aeruginosa isolates from chronically-infected cystic fibrosis patients. Journal of Bacteriology194:4857-4866.
  5. Stressmann FA, Rogers GB, van der GastCJ, Marsh P, Vermeer LS, Carroll MP, Hoffman LR, Daniels TWV, Patel N, Forbes B, Bruce KD (2012) Long-term cultivation-independent microbial diversity analysis demonstrates that bacterial communities infecting the cystic fibrosis lung are stable and resilient. Thorax67: 867-873 with an editorial by John LiPuma also in the same issue.
  6. Daniels TWV, Rogers GB, Stressmann FA, van der Gast CJ, Bruce KD, Jones G, Connett G, Legg J, Carroll MP. Impact of antibiotic treatment for pulmonary exacerbations on bacterial diversity in cystic fibrosis. Journal of Cystic Fibrosis (in press)
  7. Fernandes ES, Liang L, Smillie SJ, Kaiser F, Purcell R, Rivett DW, Alam S, Howat S, Collins H, Thompson SJ, Keeble JE, Riffo-Vasquez Y, Bruce KD, Brain SD (2012) TRPV1 deletion enhances local inflammation and accelerates the onset of Systemic Inflammatory Response Syndrome. Journal of Immunology 188:5741-5751.
  8. Payne MS, Goss KCW, Connett GJ, Legg JP, Bruce KD,Chalker V (2012) A quantitative analysis of Ureaplasma urealyticum and Ureaplasma parvum compared with host immune response in preterm neonates at risk of developing bronchopulmonary dysplasia. Journal of Clinical Microbiology50: 909- 914.
  9. Rogers GB, Carroll MP, Bruce KD (2012) Enhancing the utility of existing antibiotics by targeting bacterialbehaviour?British Journal of Pharmacology 165: 845-85.
  10. Stressmann, FA, RogersGB, Marsh P, Lilley AK, Daniels TWV, Carroll MP, Hoffman LR, Jones G, Allen CE, Patel N, Forbes B, Tuck A, Bruce KD (2011) Does bacterial density in cystic fibrosis sputum increase prior topulmonary exacerbation?Journal of Cystic Fibrosis10: 357-365
  11. Bruce KD, RogersGB, Patel N (2011) Microbiological insights into respiratory infections and the opportunities for inhaled therapy Journal of Drug Delivery Science and Technology21: 301-309.
  12. Stressmann FA, Rogers GB, Chan SW, Howarth PH, Harries PG, Bruce KD, Salib RJ (2011) Characterization of bacterial community diversity in chronicrhinosinusitis infections using novel culture-independent techniques. American Journal of Rhinology & Allergy25:133-140
  13. van der Gast CJ, Walker AW, Stressmann FA, Rogers GB, Scott P, Daniels TW, Carroll MP, Parkhill J, Bruce KD (2011) Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communitiesISME J5: 780-791.
  14. JunkesC, Harvey RD, Bruce KD, Doelling R, Bagheri M, Dathe M (2011) Cyclic antimicrobial R-, W-rich peptides: the role of peptide structure and E. coli outer and inner membranes in activity and the mode of action. European Biophysics Journal with Biophysics Letters 40: 515- 528
  15. RogersGB, Hoffman LR, Johnson MW, Mayer-Hamblett N, Schwarze J, CarrollMP, Bruce KD (2011) Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset. Expert Review of Molecular Diagnostics 11: 197-206
  16. Stressmann FA, Rogers GB, Klem ER, LilleyAK, Wolfgang MC, Donaldson SH, Daniels T, CarrollMP, Boucher RC,Bruce KD (2011) Analysis of the bacterial communities present in the lungs of cystic fibrosis patients from American and British centers. Journal of Clinical Microbiology49:281-291.
  17. Rogers GB, Marsh P, Stressmann AF, Allen CE, Daniels TV, Carroll MP, Bruce KD (2010) The exclusion of dead bacterial cells is essential for accurate molecular analysis of clinical samples. Clinical Microbiology and Infection16:1656-1658.
  18. Rogers GB, Bruce KD. Next-generation sequencing in the analysis of human microbiota: essential considerations for clinical application. Molecular Diagnostics and Therapy 14:343-50.
  19. Slater FR, Bruce KD, Ellis RJ, Lilley AK, Turner SL (2010) Determining the effects of a spatially heterogeneous selection pressure on bacterial population structure at the sub-millimetre scale. Microbial Ecology 60:873-84.
  20. Rogers GB, Hoffman LR, Whiteley M, Daniels TW, Carroll MP, Bruce KD (2010) Revealing the dynamics of polymicrobial infections. Trends in Microbiology 18:357-64.
  21. Rogers GB, Fine D, Walker AW, Daniels TW, Carroll MP, Hoffman LR, Bruce KD (2010) Insights obtained by contrasting the microbiota of the human lung and gut. Gut Microbes1:85-93.
  22. Rogers GB, Russell LE, Preston PG, Marsh P, Collins JE, Saunders J, Sutton J, Fine D, Bruce KD, Wright M (2010) Characterisation of bacteria in ascites--reporting the potential of culture-independent, molecular analysis. European Journal of Clinical Microbiology and Infectious Diseases.29:533-41.
  23. Rogers GB, Stressmann FA, Walker AW, Carroll MP, Bruce KD (2010) Lung infections in cystic fibrosis: deriving clinical insight from microbial complexity. Expert Reviews of Molecular Diagnostics 10:187-96.
  24. Stressmann FA, Connett GJ, Goss K, Kollamparambil TG, Patel M, Payne MS, Puddy V, Legg J, Bruce KD, Rogers GB (2010) Using culture-independent tools to characterise the bacteria
    in endo-tracheal aspirates from pre-term infants at risk of BPD Journal of Perinatal Medicine. 38:333-7.
  25. Spasenovski T, Carroll MP, Lilley AK, Bruce KD (2010) Modelling the bacterial communities associated with cystic fibrosis lung infections European Journal of Clinical Microbiology and Infectious Diseases29:319-28.
  26. Rogers GB, Skelton SP, Serisier D, van der Gast CJ, Bruce KD (2010) Determining CF lung microbiology: a comparison of spontaneous and serially induced sputum samples using T-RFLP profiling. Journal of Clinical Microbiology 48:78-86.
  27. Payne MS, Goss KC, Connett GJ, Kollamparambil T, Legg JP, Thwaites R, Ashton M, PuddyV, Bruce KD(2010) Molecular microbiological characterization of pre-term neonates at risk of Bronchopulmonary Dysplasia Pediatric Research 67:412-8.
  28. Johnson MW, Rogers GB, Bruce KD, Lilley AK, von Herbay A, Forbes A, Ciclitira PJ, Nicholls RJ. (2009) Bacterial community diversity in cultures derived from healthyand inflamed ileal pouches after restorative proctocolectomy. Inflammatory Bowel Disease15:1803-1811.
  29. Rogers GB, Carroll MP, Bruce KD (2009) Studying bacterial infections throughculture-independent approaches. Journal of Medical Microbiology58:1401-18.
  30. Rogers GB, Daniels TW, Tuck A, Carroll MP, Connett GJ, David GJ, Bruce KD (2009) Studying bacteria in respiratory specimens by using conventional and molecular microbiological approaches. BMC Pulmonary Medicine9:14
  31. Spasenovski T, Carroll MP, Payne MS, Bruce KD (2009) Molecular analysis of diversitywithin the genus Pseudomonas in the lungs of cystic fibrosis patients. DiagnosticMicrobiology and Infectious Disease63:261-7.
  1. Rogers GB, Stressmann FA, Koller G, Daniels T, Carroll MP, Bruce KD. (2008) Assessingthe diagnostic importance of nonviable bacterial cells in respiratory infections.Diagnostic Microbiology and Infectious Disease62:133-41.
  2. Slater FR, Bruce KD, Ellis RJ, Lilley AK, Turner SL (2008) Heterogeneous selectionin a spatially structured environment affects fitness tradeoffs of plasmidcarriage in pseudomonads. Applied and Environmental Microbiology74:3189-97.
  3. Demirkan I, Williams HF, Dhawi A, Carter SD, Winstanley C, Bruce KD, Hart CA (2006) Characterization of a spirochaete isolated from a case of bovine digitaldermatitis. Journal of Applied Microbiology101:948-55.
  4. Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Jones G, Kehagia V, Connett GJ,Bruce KD (2006) Use of 16S rRNA gene profiling by terminal restriction fragment length polymorphism analysis to compare bacterial communities in sputum and mouthwashsamples from patients with cystic fibrosis. Journal of Clinical Microbiology 44:2601-4.
  5. Green GL, Brostoff J, Hudspith B, Michael M, Mylonaki M, Rayment N, StainesN, Sanderson J, Rampton DS, Bruce KD (2006) Molecular characterization of the bacteria adherent to human colorectal mucosa. Journal of Applied Microbiology100:460-9.
  6. Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Kehagia V, Jones GR, Bruce KD (2005)Bacterial activity in cystic fibrosis lung infections. Respiratory Research6:49.
  7. Rogers GB, Carroll MP, Connett GJ, Serisier DJ, Hockey PM, Kehagia V, Jones GR, Bruce KD (2005). Bacterial community diversity in the CF lung. Pediatric Pulmonology 40, S28 pp 1-62.
  8. Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Jones G, Bruce KD (2004) Characterization of bacterial community diversity in cystic fibrosis lunginfections by use of 16S ribosomal DNA terminal restriction fragment lengthpolymorphism profiling. Journal of Clinical Microbiology 42:5176-83.
  9. Rogers GB, Hart CA, Mason JR, Hughes M, Walshaw MJ, Bruce KD (2003). Bacterialdiversity in cases of lung infection in cystic fibrosis patients: 16S ribosomalDNA (rDNA) length heterogeneity PCR and 16S rDNA terminal restriction fragmentlength polymorphism profiling. Journal of Clinical Microbiology 41:3548-58
  10. Bruce KD, Hughes MR (2000) Terminal restriction fragment length polymorphismmonitoring of genes amplified directly from bacterial communities in soils andsediments. Molecular Biotechnology16:261-9.
  11. Kandeler E, Tscherko D, Bruce KD, Stemmer M, Hobbs PJ, Bardgett RD, and Amelung W (2000) Structure and function of the soil microbial community in microhabitats of a heavy metal polluted soil. Biology and Fertility of Soils 32: 390-400.
  12. Bruce KD, Jones TH, Bezemer TM, Thompson LJ, and Ritchie DA (2000) Effect of elevated carbon dioxide levels on bacterial communities in model terrestrial ecosystems. Global Change Biology6: 427-434.
  13. Holt RJ, Bruce KD, and Strike P (1999) Conservation of transposon structures in soil bacteria. FEMSMicrobiology Ecology 30: 25-37.
  14. Jones TH, Thompson LJ, Lawton JH, Bezemer TM, Bardgett RD, Blackburn TM, Bruce KD, Cannon PF, Hall GS, Hartley SE, Howson G, Jones CG, Kampichler C, Kandeler E, Ritchie DA (1998) Impacts of rising atmospheric carbon dioxide on model terrestrial ecosystems. Science 280:441-3.
  15. Bruce KD (1997) Analysis of mer Gene Subclasses within Bacterial Communities in Soils and Sediments Resolved by Fluorescent-PCR-Restriction Fragment Length Polymorphism Profiling. Appliedand Environmental Microbiology63:4914-4919.
  16. Osborn AM, Bruce KD, Strike P, Ritchie DA (1997) Distribution, diversity andevolution of the bacterial mercury resistance (mer) operon. FEMS Microbiology Reviews19:239-62.
  17. Viegas CA, Lilley AK, Bruce K, and Bailey MJ (1997) Description of a novel plasmid replicative origin from a genetically distinct family of conjugative plasmids associated with phytosphere microflora. FEMS Microbiology Letters 149: 121-127.
  18. Holt RJ, Strike P, Bruce KD (1996) Phylogenetic analysis of tnpR genes in mercuryresistant soil bacteria: the relationship between DNA sequencing and RFLP typing approaches. FEMS Microbiol Letters 144:95-102.
  19. Pearson AJ, Bruce KD, Osborn AM, Ritchie DA, Strike P (1996) Distribution of class II transposase and resolvase genes in soil bacteria and their association withmer genes. Applied and Environmental Microbiology 62:2961-5.
  20. Osborn AM, Bruce KD, Ritchie DA, Strike P (1996) The mercury resistance operon ofthe IncJ plasmid pMERPH exhibits structural and regulatory divergence from other Gram-negative mer operons. Microbiology. 142:337-45.
  21. Safarnejad A, Collin HA, Bruce KD, and McNeilly T (1996) Characterization of alfalfa (Medicago sativa L.) following in vitro selection for salt tolerance. Euphytica. 92: 55-61.
  22. Osborn AM, Bruce KD, Strike P, and Ritchie DA (1995) Sequence conservation between regulatory mercury resistance genes in bacteria from mercury polluted and pristine environments. Systematic and Applied Microbiology 18: 1-6.
  23. Bruce KD, Osborn AM, Pearson AJ, Strike P, Ritchie DA (1995) Genetic diversity within mer genes directly amplified from communities of noncultivated soil andsediment bacteria. Molecular Ecology4:605-12.
  24. Cash P, Argo E, Bruce KD (1995) Characterisation of Haemophilus influenzae proteinsby two-dimensional gel electrophoresis. Electrophoresis. 16:135-48.
  25. Osborn AM, Bruce KD, Strike P, Ritchie DA (1993) Polymerase chainreaction-restriction fragment length polymorphism analysis shows divergence amongmer determinants from gram-negative soil bacteria indistinguishable by DNA-DNAhybridization. Applied and Environmental Microbiology 59:4024-30.
  26. Bruce KD, Hiorns WD, Hobman JL, Osborn AM, Strike P, Ritchie DA (1992)Amplification of DNA from native populations of soil bacteria by using thepolymerase chain reaction. Applied and Environmental Microbiology58:3413-6.
  27. Forbes KJ, Bruce KD, Ball A, Pennington TH (1992) Variation in length and sequence of porin (ompP2) alleles of non-capsulate Haemophilus influenzae. Molecular Microbiology 6:2107-12.
  28. Forbes KJ, Bruce KD, Jordens JZ, Ball A, Pennington TH (1991) Rapid methods in bacterial DNA fingerprinting. Journal of General Microbiology. 137:2051-8.
  29. Bruce KD, Pennington TH (1991) Clonal analysis of non-typable Haemophilus influenzae by sodium dodecyl sulphate-polyacrylamide gel electrophoresis of wholecell polypeptides.Journal of Medical Microbiology. 34:277-83
  30. Bruce KD, Jordens JZ (1991) Characterization of noncapsulate Haemophilus influenzaeby whole-cell polypeptide profiles, restriction endonuclease analysis, and rRNAgene restriction patterns. Journal of Clinical Microbiology29:291-6.