Randomized Trials Published in Chinese or Western Journals:Comparative Empirical Analysis

Marianna Purgato, PsychD, Andrea Cipriani, MD, PhD, Corrado Barbui, MD

Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Verona (Italy)

SUPPLEMENTAL appendix

REFERENCES OF INCLUDED STUDIES

WESTERN STUDIES

Allard P, Gram L, Timdahl K, Behnke K, Hanson M, Sogaard J. Efficacy and tolerability of venlafaxine in geriatric outpatients with major depression: a double-blind, randomised 6-month comparative trial with citalopram. International Journal of Geriatric Psychiatry 2004;19(12):1123-30.

Andersen J, Bech P, Benjaminsen S, Bjerre M, Bojhlm S, Christensen P, Gjerris A, Hansted L, Jensen E, Kragh-Sorensen P, Kristensen CB, Kyneb P, Loldrup D, Madsen OF, Pedersen OL, Rafaelsen OJ, Rasmussen S, Reisby N, Sevaj F, Simonsen P, Thomsen HY, Vestegaard P. Citalopram: clinical effect profile in comparison with clomipramine. A controlled multicentre study. Psychopharmacology 1986;90:131-138.

Berlanga C, Flores-Ramos M. Different gender response to serotonergic and noradrenergic antidepressants. A comparative study of the efficacy of citalopram and reboxetine.. Journal of affective disorders 2006;95:119-123.

Bouchard JM, Delaunay J, Delisle JP, Grasset N, Mermberg PF, Molczadzki M, Pagot R, Richou H, Robert G, Ropert R, Schuller E, Verdeau-Pailles J, Zarifian E, Hopfner HE. Citalopram versus maprotiline: a controlled, clinical multicentre trial in depressed patients. Acta Psychiatrica Scandinavica 1987;76(5):583-592.

Bougerol T, Scotto JC, Patris M, Strub N, Lemming O, Hopfner Petersen HE. Citalopram and fluoxetine in major depression: Comparison of two clinical trials in a psychiatrist setting and in general practice (first trial). Clinical drug Investigation 1997a;14(2):77-89.

Bougerol T, Scotto JC, Patris M, Strub N, Lemming O, Hopfner Petersen HE. Citalopram and fluoxetine in major depression: Comparison of two clinical trials in a psychiatrist setting and in general practice (first trial). Clinical drug Investigation 1997b;14(2):77-89.

Burke W J, Gergel I, Bose A. Fixed-dose trial of the single isomer SSRI escitalopram in depressed outpatients. Journal of Clinical Psychiatry 2002;63(4):331-336.

Castanedo de Alba L, Meixueiro-Montes De Oca R. An open-label, controlled study of citalopram versus moclobemide in patients with major depression. Current Therapeutic Research 1998;59(2):107-115.

Colonna L, Andersen H F, Reines E H. A randomized, double-blind, 24-week study of escitalopram (10 mg/day) versus citalopram (20 mg/day) in primary care patients with major depressive disorder. Current Medical Research and Opinion 2005;21(10):1659-1668.

De Wilde J, Mertens C, Fredricson-Overo K, Petersen HE. Citalopram versus mianserin. A controlled, double-blind trial in depressed patients. Acta Psychiatrica Scandinavica 1985;72(1):89-96.

Ekselius L, von Knorring L, Eberhard G. A double-blind multicenter trial comparing sertraline and citalopram in patients with major depression treated in general-practice. International Clinical Psychopharmacology 1997;12(6):323-331.

Gastpar M, Singer A, Zeller K. Comparative efficacy and safety of a once-daily dosage of hypericum extract STW3-VI and citalopram in patients with moderate depression: A double-blind, randomised, multicentre, placebo-controlled study. Pharmacopsychiatry 2006;39(2):66-75.

Gravem A, Amthor KF, Astrup C, Elgen K, Gjessing LR, Gunby B, Pettersen RD, Kyrdalen L, Vaadal J, Ofsti E, Aarvold A. A double-blind comparison of citalopram (Lu 10-171) and amitriptyline in depressed patients. Acta Psychiatrica Scandinavica 1987;75(5):478-486.

Hosak L, Tuma I, Hanus H. A comparative study of three antidepressants with a different mechanism of action in hospitalized patients.. Ceska a Slovenska Psychiatrie 1999;95(3):146-156.

Karlsson I, Godderis J, Augusto De Mendonca Lima C, Nygaard H, Simanyi M, Taal M, Eglin M. A randomised, double-blind comparison of the efficacy and safety of citalopram compared to mianserin in elderly, depressed patients with or without mild to moderate dementia. International Journal of Geriatric Psychiatry 2000;15:295-305.

Khanzode SD, Dakhale GN, Khanzode SS, Saoji A, Palasodkar R. Oxidative damage and major depression: The potential antioxidant action of selective serotonin-re-uptake inhibitors.. Redox Report 2003;8(6):365-370.

Kyle CJ, Petersen HE, Overo KF. Comparison of the tolerability and efficacy of citalopram and amitriptyline in elderly depressed patients treated in general practice. Depression and Anxiety 1998;8(4):147-153.

Langworth S, Bodlund O, Agren H. Efficacy and tolerability of reboxetine compared with citalopram: A double-blind study in patients with major depressive disorder. Journal of Clinical Psychopharmacology 2006;26(2):121-127.

Leinonen E, Skarstein J, Behnke K, Agren H, Helsdingen JT. Efficacy and tolerability of mirtazapine versus citalopram: a double-blind, randomized study in patients with major depressive disorder. International Clinical Psychopharmacology 1999;14(6):329-337.

Lepola U M, Loft H, Reines E H. Escitalopram (10-20 mg/day) is effective and well tollerated in a placebo-controlled study in depression in primary care. International Clinical Psychopharmacology 2003;18(4):211-217.

Matreja PS, Badyal DK, Khosla P, Deswal RS. Effectiveness and acceptability of sertraline and citalopram in major depressive disorder: pragmatic randomized open-label comparison. Human Psychopharmacology 2007;22(7):477-482.

Moeller O, Hetzel G, Rothermundt M, Michael N, Nyhuis PW, Suslow T, Arolt V, Erfurth A. Oral citalopram and reboxetine challenge tests before and after selective antidepressant treatment. Journal of Psychiatric Research 2003;37(3):261-2.

Moore N, Verdoux H, Fantino B. Prospective, multicentre, randomized, double-blind study of the efficacy of escitalopram versus citalopram in outpatient treatment of major depressive disorder. International Clinical Psychopharmacology 2005;20(20:131-137).

Navarro V, Gasto C, Torres X, Marcos T, Pintor L. Citalopram versus nortriptyline in late-life depression: a 12-week randomized single-blind study. Acta Psychiatrica Scandinavica 2001;103(6):435-440.

Ou JJ, Xun GL, Wu RR, Li LH, Fang MS, Zhang HG, Xie SP, Shi JG, Du B, Yuan XQ, Zhao JP. Efficacy and safety of escitalopram versus citalopram in major depressive disorder: a 6-week, multicenter, randomized, double-blind, flexible-dose study.. Psychopharmacology (Berl) 2010 [Epub ahead of print].

Rosenberg C, Damsbo N, Fuglum E, Jacobsen LV, Horsgard S. Citalopram and imipramine in the treatment of depressive patients in general-practice. A Nordic multicentre clinical study. International Clinical Psychopharmacology 1994;9(suppl.1):41-8.

Shaw DM, Thomas DR, Briscoe MH, Watkins SE, Crimmins R, Harris B, Lovett J, Raj M, Lloyd AT, Osborne C, Hughes G, Waheed W, Davies J, Rolfe AB, Satheesan E, Snape A, Evans VM, Patel N, Bari MA. A comparison of the antidepressant action of citalopram and amitriptyline.. British Journal of Psychiatry 1986;149:515-7.

Stahl SM. Placebo-controlled comparison of the selective serotonin reuptake inhibitors citalopram and sertraline. Biological Psychiatry 2000;48(894-901).

Timmerman L, Haffmans PMJ, Hoogduin CA. Citalopram in major depression: a comparative study with Fluvoxamine, Preliminary results. Past, Present and Future of Psychiatry 1993:982-6.

Yevtushenko VY, Belous AI, Yevtushenko YG, Gusinin SE, Buzik OJ, Agibalova TV. Efficacy and tolerability of escitalopram versus citalopram in major depressive disorder: a 6-week, multicenter, prospective, randomized, double-blind, active-controlled study in adult outpatients. Clin Ther 2007;29(11):2319-32.

Flexible-dose comparison of the safety and efficacy of Lu 26-054 (escitalopram), citalopram, and placebo in the treatment of major depressive disorder. (accessed Jan 11, 2010).

A double-blind, placebo controlled, fixed-dosage study comparing the efficacy and tolerability of paroxetine CR and citalopram to placebo in the treatment of Major Depressive Disorder with anxiety.Jefferson J, JohnGriestAmericanCollege of Neuropsychopharmacology 39th Annual Meeting, Puerto Rico.Nov 12, 2000.

CHINESE STUDIES

Du C, Che L. Efficacy analysis of citalopram and amitriptyline in the treatment of depression. Chinese Journal of health Psychology 2004;12(6):424-426.

Fu R, Zhu C. Compariaon of citalopram and amitriptyline in treatment of depression. Medical Journal of the Chinese People's Armed Police Forces 2006;17(4):250-251.

Gao B, Yue S, Liu J. Study on citalopram in the treatment of aged depression. Practical Geriatrics 2005;19(1):42-43.

Gong C, Xu H, Xiang D, Zhou X. Comparative study on depression treated by citalopram or mirtazapine. Journal of Clinical Psychological Medicine 2005;15(3):154-155.

Huang P, Li Z, Wang C. A clinical controlled study of citalopram and fluoxetine in the treatment of depression. Journal of Clinical Psychological Medicine 2004;14(6):364-365.

Huang K. Contrast study of citalopram and fluoxetine in treatment of depression. Modern Medicine and Health 2006;20(10):1456-1457.

Huang J, Sun Z. A control study of citalopram and fluoxetine in first-episode senile depression. Journal of Clinical Psychosomatic Diseases 2006;12(3):175-176.

Li XH, Zhang HW, Pang YD. A comparative evaluation on the effect of citalopram and amitriptyline in treating senile depression. Chinese Journal of Clinical Rehabilitation 2004;8(27):5762-5763.

Li X, Sun L, Li Z. A comparative study of the efficacy of citalopram in the treatment of depression. Sichuan Mental Health 2005;18(4):214-216.

Li J, Shen WW, Liu Y, Xu L, Liu SM, Kuang WH. The effectiveness and safety of escitalopram in the treatment of major depression: A randomized double-blind active-drug controlled trial. Chinese Journal of Evidence-Based Medicine 2006;6(8):552-556.

Li DS, Wang C, Yu J. A comparative study of citalopram and paroxetine in the treatment of depression. Medical Journal of Chinese People's Health 2006;18(6):460-461.

Li D, Yu J, Pang Y. Comparative study of citalopram and venlafaxine in the treatment of depression. Journal of Clinical Psychological Medicine 2005;15(3):158-159.

Li Z, Zeng Z, Liu Q. Clinical controlled study of citalopram versus amitriptyline in treatment of depressive disorder. Sichuan Mental Health 2004;17(2):76-78.

Liang C, Liu L, Zhang X. A comparative study of citalopram and fluoxetine in the treatment of depression Shandong Archives of Psychiatry;18(2):82-83.

Liang K, Fan X. Comparative study of citalopram and mianserin in the treatment of senile depression. Journal of Clinical Psychological Medicine 2006;16(1):32-33.

Lin J, HUuang Y, Chen G, Lin Z, Zhu G. Comparison of citalopram and amitriptyline in treatment of depression. Chinese Journal of New Drugs and Clinical Remedies 2001;20(5):351-354.

Liu J, Gan L, Feng D. A control study on citalopram and amitriptyline in the treatment of aged patients with depression. China Journal of Health Psychology 2006;14(4):450-451.

Ma Z, Zheng Z, Zhuang X. A comparative study of citalopram and amitriptyline in the treatment of depression. Shandong Archives of Psychiatry 2004;17(2):79-81.

Pan K, Liu X, Yang J, Zhu L, Wang X, Wang X, Yang S. Cost-effectiveness analysis of depression treatment with paroxetine, venlafaxine and citalopram. Chinese Journal of Clinical rehabilitation 2005;9(28):16-17.

Qiao J, Yu J, Hao Z. Comparative study of citalopram and paroxetine in treatment of depression. Journal of Clinical Psychological Medicine 2005;15(5):281-282.

Qiu C, Xiao B, Shi Z, Xie W, Zhang F, Qiu K. The effect observation of citalopram in the treatment of patients with depression. Journal of Shantou University Medical College 2005;18(4):216-217.

Ren Y. Controlled study of citalopram and sertraline the treatment of depression. Medical Journal of Chinese People's Health 2006;18(7):580-581.

Shi Y, Liu H, Ding D. Comparative study of citalopram and maprotiline in treatment of depression. Journal of Clinical Psychological Medicine 2005;15(6):356-357.

Song H, Guo B, Chen Z. Comparisons of citalopram and fluoxetine in first-episode depression. Journal of Clinical Psychosomatic Disease 2004;10(3):180-181.

Tan X, Li H, Du Z. A double blind study of citalopram and amitriptyline in the treatment of aged depression. Shandong Archives of Psychiatry 2004;17(4):202-203.

Tang W, Huang W. Efficacy of citalopram and amitriptyline in the treatment of patients with depression. Shangai Archives of Psychiatry 2005;17(2):87-88.

Tao W, LV C, Li W. A comparative study between citalopram and paroxetine in the treatment of depression. Medical Journal of Chinese People's Health 2005;17(9):491-492.

Wan Y, Li M, Han Y. A control study of citalopram in the treatment of senile depression. Journal of Clinical Psychosomatic Diseases 2006;12(4):243-244.

Wang X. A double-blind control study on the effect of citalopram and imipramine on depression. Modern Forums in Basic 2003;7(12):1111-1112.

Wang J, Liu X, Yang G. A study of citalopram in the treatment of depression. Journal of Clinical Psychological Medicine 2004;14(1):16-17.

Wang J, Yang C, Wang Y. Comparative study of citalopram vs mirtazapine in treatment of senile depressive patients. China Journal of Health Psychology 2006;14(5):552-553.

Xu M, Ji L. A comparative study of citalopram and amitriptyline in the treatment of out-patients with depression. Chinese Mental Health Journal 2005;19(5):353-354.

Yu J, Wang P, Zhang G, Hao Z. Controlled study of citalopram and venlafaxine in treatment of patients with senile depression. Journal of Clinical Psychological Medicine 2006;16(2):92-93.

Zhang H, Cheng J, Wang G. Comparison of citalopram and venlafaxine for depressive disorder. Chinese journal of Clinical Rehabilitation 2005;9(36):4-6.

Zhang F, Mao Q. A study of citalopram in treatment of old age depression 2006;14(4):434-435.

Zhao H, Guan T. A control study in the treatment of depressive disorder with citalopram and fluoxetine. Evaluation and Analysis of Drug-Use in Hospitals of China 2006;6(2):106-108.

Zhou X, Liu Z, Zhu H, Ding Y, Zhang A, Tao Y, Huang X. Treatment of depression with citalopram and venlafaxine: a clinical comparative study. Medical Journal of National Defending Forces in North China 2005;17(2):90-91.