RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES,
KARNATAKA, BANGALORE
COMPLETED PROFORMA FOR REGISTRATION
OF SUBJECT FOR DISSERTATION
“A COMPARATIVE CLINICAL STUDY OF DVATRIMSHAKA GUGGULU
AND KATIBASTI WITH PRASARINI TAILA IN GRIDHRASI”
BY
DR. VASUNDARA.S
M.D(Ayu), SCHOLAR
DEPARTMENT OF P.G. STUDIES IN KAYACHIKITSA
S.D.M COLLEGE OF AYURVEDA, KUTHPADY, UDUPI
GUIDE
DR. SHREEDHAR HOLLA.,M.D. (AYU)
PROFESSOR
DEPT. OF P.G. STUDIES IN KAYACHIKITSA
S.D.M. COLLEGE OF AYURVEDA,
KUTHPADY, UDUPI-574118
COGUIDE
DR.VEERAKUMARA.K.,M.D.(AYU)
ASST.PROFESSOR
DEPT. OF P.G. STUDIES IN KAYACHIKITSA
S.D.M. COLLEGE OF AYURVEDA,
KUTHPADY, UDUPI-574118
2009-2010
S.D.M. COLLEGE OF AYURVEDA
KUTHPADY, UDUPI-574118
From:
Dr. VASUNDARA.S
M.D.(Ayu), SCHOLAR
DEPT. OF P.G. STUDIES IN KAYACHIKITSA
S.D.M. COLLEGE OF AYURVEDA,
KUTHPADY, UDUPI - 574118
To,
THE REGISTRAR,
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES
BANGALORE
Through,
THE PRINCIPAL
S.D.M. COLLEGE OF AYURVEDA
KUTHPADY, UDUPI - 574118
Respected Sir,
SUB: Submission of completed proforma for registration of subject for dissertation.
I request you to kindly register the below mentioned subject against my name for the submission of the dissertation to the Rajiv Gandhi University of Health Sciences, Bangalore for the partial fulfillment of M.D ( AYU ) in Kayachikitsa.
Title of Dissertation:
“A COMPARATIVE CLINICAL STUDY OF DVATRIMSHAKA GUGGULU
AND KATIBASTI WITH PRASARINI TAILA IN GRIDHRASI”
Here with, I am enclosing completed proforma for registration of subject for Dissertation. Thanking You,
yours faithfully,
Place: Udupi
Date: ( DR. VASUNDARA.S)
1) NAME OF THE CANDIDATE : DR. VASUNDARA.S
M.D(Ayu) SCHOLAR,
DEPT.OF P.G.STUDIES IN
KAYACHIKITSA
S.D.M.COLLEGE OF AYURVEDA,
KUTHPADY, UDUPI-574118
PERMANENT ADDRESS : DR. VASUNDARA.S
D/O SHATHARAJU.K
44 PRASHANTHA ,RCS LAYOUT
KAGGALIPURA,
KANAKAPURAMAIN ROAD,
BENGALURU-560082
2) NAME OF THE INSTITUTION: S.D.M. COLLEGE OF AYURVEDA,
KUTHPADY, UDUPI-574118
KARNATAKA
3) COURSE OF STUDY AND
SUBJECT : M.D.(AYURVEDA)IN KAYACHIKITSA
4) DATE OF ADMISSION OF
COURSE :24th September 2009
5) TITLE OF THE TOPIC STUDY :
“A COMPARATIVE CLINICAL STUDY OF DVATRIMSHAKA GUGGULU
AND KATIBASTI WITH PRASARINI TAILA IN GRIDHRASI”
6) BRIEF RESUME OF THE INTENDED WORK
6.1) NEED FOR THE STUDY:
A normal daily life without moving spine is impossible for any human being.In
the present world, the advancement of busy,professional,social life,improper sitting
postures,continuous and over exertion,jerking movements during travelling and
sports- all these have undue pressure effects on the spine,which results in the most
common disorder called the Low back pain.50 percent of the working population
have back pain every year1.Most of the persons will have radicular pain and this
comes under the Sciatica Syndrome.
Gridhrasi is a shoola pradhanaja vyadhi characterized by ruk in sphik,
kati, uru, janu, jangha, pada and also associated with toda, stamba,
muhurspandana2.The lakshanas of Gridhrasi can be well correlated with the
“Sciatica” in modern.
Ayurveda has explained Shamana line of treatement that includes oral
administration of medicines,Snehana,Svedana,Basti etc.Katibasti is one such
procedure which is not mentioned in our classics,but pacticed by many scholars.
Among the snehanas Prasarini taila3 is indicated in Gridhrasi.
The oral administration of medicine is atmost importance as it is very easy
and also effective.Many herbal combinations described in Ayurveda yet to be
explored.Dvatrimshaka guggulu4 is one such yoga prescribed for vatavyadhis
including Gridhrasi.
In this study an attempt is made to evaluate the comparative effect of
Dvatrimshaka guggulu and Kati basti with Prasarini taila in Gridhrasi.
6.2) REVIEW OF LITERATURE
Gridhrasi is a vata vyadhi characterized by shoola,sthamba,toda,spandana.These
symptoms initially affect sphik,as well as posterior aspect of kati & then gradually
radiates to posterior aspects of ooru,janu,jangha,paada2.This is manifested due to
vatakara ahara vihara.Kati basti with Prasarini taila3and Dvatrimshaka guggulu4
are indicated in the management of Gridhrasi & are said to produce relief of the
condition.
PREVIOUS WORKS DONE:
1) A comparative clinical study was conducted to evaluate the efficacy of Navjeevanarasa and Rasna guggulu in patients of Gridhrasi.Study concluded with better remission of symptoms in patients treated with Navajeevanarasa5.
2) A study was conducted to find the efficacy of Rasna guggulu along with Shodana therapy by Virechana followed by Basti karma.The study proved Shodana along with Shamana is efficacious in Gridhrasi6.
3) A comparative clinical study was designed to conducted to find out the efficacy of Agnikarma and Matrabasti in Gridhrasi.The study revealed that Agnikarma and Matrabasti have got equal effect in Gridhrasi with 44% improvement7.
4) A single blind clinical study was carried out with the pretest and post test design;where in 20 patients of Gridhrasi were subjected to Kati basti with Vajigandhadi taila for a period of 6days.The result showed best remission of the symptoms in majority of patients, though complete cure was recorded in none8.
6.3) OBJECTIVES OF THE STUDY:
1) To evaluate the therapeutic effect of Dvatrimshaka guggulu in patients suffering
from Gridhrasi.
2) To evaluate the therapeutic effect of Kati basti with Prasarini taila in patients
suffering from Gridhrasi.
3)To evaluate the combined effect of Dvatrimshaka guggulu & Kati basti with
Prasarini taila in patients suffering from Gridhrasi.
7) MATERIALS AND METHODS :
7.1) Source of data:
Minimum 30 patients diagnosed as Gridhrasi will be taken for
study from OPD and IPD of SDM Ayurveda Hospital, Udupi, Karnataka.
7.2) Method of collection of data:
A special proforma will be prepared with all points of history taking, physical
signs, symptoms as mentioned in Ayurveda and lab investigations will be carried
out as mentioned in Allied sciences. Accordingly, patients are selected and will be
subjected to detailed clinical history and complete physical examinations.
Selected patients are randomly placed under three groups so in each group
minimum 10 patients will be included.
Design of the study:
It will be a single blind comparative clinical study with pre-test and post-test design wherein a minimum 30 patients suffering from Gridhrasi will be selected irrespective of their gender, cast or creed. The parameters of signs, symptoms will be scored on the basis of standard method and will be analyzed statistically.
Group A: Administration of Dvatrimshaka guggulu 500mg–2tab thrice a day for 7 days.
Group B: Administration of Kati basti with Prasarini taila once a day for 7 days.
Group C : Administration Dvatrimshaka guggulu 500mg–2tab thrice a day
Administration of Kati basti with Prasarini taila, simultaneously for 7days.
Follow up : 28 days with weekly follow up
Inclusion Criteria:
1) Patients presenting with Pratyatma Lakshanas of Gridhrasi.
2) Patients presenting with the signs and symptoms of Sciatica.
3) Patients between the age of 16 to 60 years.
Exclusion Criteria:
1) Congenital deformities of spine
2) Trauma or injury to the spine.
3) Neoplastic conditions of the spine.
4) Infections of the spine.
5) Patients with any other systemic illness.
Assessment Criteria:
Subjective Parameters:
The improvement in the patients will be assessed on the basis of relief in the Signs Symptoms of the disease.
Objective Parameters:
1.Greenough & Fraser Scoring method
2.Herron & Turners Rating
3.Sugar baker & Barofsky Clinical Mobility Scale
4.Oswestry disability Assessment Questionaire
7.3) Does the study require any investigations or interventions to be conducted on patients or other humans or animals? If so please describe briefly:
Study will be conducted on Gridhrasi patients only.
No animal experiments will be done
.
Investigations:
1) Radiological: X-ray of Lumbo-sacral spine AP & lateral views if
necessary.
2) Routine : Haematological investigations-Hb%, TC, DC, ESR.
Urine routine and microscopic to rule out other conditions
7.4) Has ethical clearance been obtained from your institution in case of 7.3?
Yes, concurrence has been obtained from the ethical committee.
8) List of References:
1)Munro J F, Campbell I W, Editors, Macleods Clinical Examination, 10th edition, Edinburg. Hascourt publishers limited, 2000, Pp.312, Page no.270
2)Acharya Agnivesha ,Charaka samhita ,elaborated by Charaka & Dridabala with Ayurveda deepika commentary by Chakrapani Datta edited by Vaidya Yadavji Trikamji Acharya, 2008 edition, published by Choukamba Sanskrit Sansthana, Varanasi, Pp 738 , Pg no 623
3)Pandita Sharangadharacharya, Sharangadhara samhita, son of Pandita Damodara, with the commentaries Adhamallas “Deepika” and Kashiramas “Gudaartha Deepika”, edited with footnotes by Pandit Parashuram Shastry Vidya Sagar, Publisher Krishnadas Academy, Printers Choukamba Press, Varanasi, Pp no 398, Page no 225
4)Yogaratnakara, ‘vidyotini’ with Hindi commentary, commentator Vaidya Shri Lakshmipati Shastry, editor Bhishak Ratna Shri Bramha Shankara Shastry, edition 2005, published by Choukamba Sanskrit Sansthana, Varanasi, Pp no 573, Page no 528
5)A.N.Narayana.-A Clinical to evaluate the therapeutic effect of Navajeevana rasa in Gridhrasi (Unpublished Doctoral dissertation,RGUHS, Karnataka)
6)Sahu-critical stydy on the etiopathogenesis ofGridhrasi and its management with Rasna guggulu along with shodhana therapy (Unpublished Doctoral dissertation, GAU, Jamnagar, 2002)
7)Shah Ranjan Kumar –A Clinical study on Agnkarma and Matra Basti in the management of Gridhrasi (Unpublished Doctoral dissertation, GAU, Jamnagar, 2002)
8)R.Ramachandra-To evaluate the therapeutic effect of Kati Basti in patients of
Gridhrasi (Unpublished Doctoral dissertation,RGUHS, Karnataka)
9)SIGNATURE OF THE CANDIDATE :
10)REMARKS OF THE GUIDE :
11)NAME AND DESIGNATION :
11.1) GUIDE : DR. SHREEDHAR HOLLA.M.D (AYU)
PROFESSOR
DEPT. OF PG STUDIES IN KAYACHIKITSA
S.D.M. COLLEGE OF AYURVEDA
KUTHPADY, UDUPI-574118
11.2)SIGNATURE :
11.3) COGUIDE : DR.VEERAKUMARA.K.M.D.(AYU)
ASST.PROFESSOR
DEPT. OF P.G. STUDIES IN KAYACHIKITSA
S.D.M. COLLEGE OF AYURVEDA,
KUTHPADY, UDUPI-57411
11.4) SIGNATURE :
11.5)HEAD OF THE DR.G.SHRINIVASA ACHARYA.M.D.(AYU)
DEPARTMENT : PROFESSOR& HOD
DEPT. OF PG STUDIES IN KAYACHIKITSA
S.D.M. COLLEGE OF AYURVEDA
KUTHPADY, UDUPI-574118
11.6)SIGNATURE :
12) REMARKS OF THE
CHAIRMAN & PRINCIPAL:
12.1) SIGNATURE :