Professor Yi-Ming Arthur Chen
Yi-Ming A. Chen M.D., M.S., Sc.D.
Distinguished Professor, Institute of Microbiology and Immunology
National Yang-Ming University （NYMU）
Taiwan
Email:
Current Positions
Dean Office of Research and Development, NYMU
Director Incubation Cener, NYMU
Director AIDS Prevention and Research Center, NYMU
Director International Health Program, NYMU
Joint appointment
Professor Institute of Brain Research, NYMU
Institute of Clinical Medicine, NYMU
Research member Vaccine Research and Development Center
National Health Research Institute
Taiwan
Committees services in the campus:
Member: Biosafety Level 3 lab committee (2004 till mow)
Member: Sonogram committee (2009-2011)
Chairman: Ethical committee (2009-2011)
Education
1975-82 M.D., Department of Medicine, National Yang-Ming Medical College, Taiwan
1982-84 M.S., Institute of Microbiology and Immunology, NYMU, Taiwan
1986-90 Sc.D., Department of Cancer Biology (Infectious Disease and Immunity), Harvard School of Public Health, Boston, MA, USA
Working experiences
1982-1984 Teaching Assistant, Department of Microbiology and Immunology, NYMU, Taiwan
1984-1986 Aviation Doctor, Air-force General Hospital, (Military services), Taiwan
1986 Lecturer, Department of Microbiology and Immunology, NYMU
1990-1992 Visiting Scientist, Lab of Molecular Oncology, National Cancer Institute, USA
1992-1998 Associate Professor, Institute of Public Health, NYMU, Taiwan
1992-1994 Associate Research Member, Institute of Biomedical Sciences, Academia Sinica, Taiwan
1998-2007 Professor, Institute of Public Health, NYMU, Taiwan
2002-2003 Visiting Scientist, HIV Drug Resistance Program, NCI, USA
2007-2009 Professor, Department of Microbiology and Immunology, NYMU
2009-2014 Distinguished Professor, Department of Microbiology and Immunology, NYMU
2007-2010 Dean, Office of International Affairs
Advisory/steering committee and society
1992-2004 Member, AIDS Advisory Committee, Centers of Disease Control, Ministry of Health, Taiwan
2004-2009 Member, Committee for AIDS Prevention and HIV-infected People’s Rights Protection, Executive Yuan, Taiwan
1994-2009 Founder and Coordinator, Living with Hope Organization
1993-2009 Board Member, Taiwan Society of Preventive Medicine (has been elected as secretary general in 1993-1996, as chairman in 1997-2003)
1996-2006 Advisory Board on Health Issues, Consumer Foundation, Taiwan
1996-2009 Board member, Taiwan AIDS Hope Association (Founder)
1998-2006 Council of Representative, Asia Pacific AIDS Services Organization
2001-2009 Member, AIDS Education Advisory Committee, Ministry of Health, Taiwan
2004-2009 Member, Steering committee, Therapeutic Research, Education and AIDS Training in Asia (TREAT Asia) (has been elected as the chair since 2008)
2001-2003 Regional Task Force on HIV/AIDS Care and support in Asia
2002-2005 Vice Chairman, Global Chinese AIDS Network (co-founder)
2008-2010 Vice Chairman, Global Chinese AIDS Network
2001 Medical Advisory Board, OmniViral Therapeutics LLC
2005-2007 Chairman, Taiwan AIDS Quilt Association (Founder)
2006-2009 Board member, Harmony Home Association （co-founder）
2003-2009 Board member, Taiwan Society of Epidemiology
2007-2010 Chairman, Taiwan Harm Reduction Association （台灣減害協會）
2006-2009 Consultant, Centers for Disease Control, Taiwan
2007-2009 Consultant, Anti-drug Usage association, Tao-Yuan Prefecture, Taiwan （桃園縣毒品危害防制委員會）
2007-2009 Consultant, Taipei City Government
2008-2009 Board Member, Taiwan Society of Microbiology
2008-2010 Managing Supervisor, Taiwan Society of Preventive Medicine
2008-2009 Board Member, Taiwan Can Love Association (for patients suffering depression) （Co-founder）
2008-2009 TREAT Asia Steering Committee Chair
2009 Committee Member, Global Vaccine Access Council (University of Western Ontario, Canada)
Member of the following societies: International Liver Cancer Association (member #100708), American Association for Cancer Research (AACR) (member #52595), American Society of Microbiology and Immunology, American Society of Human Genetics, International AIDS Society (ID number 32042), Taiwan Society of Epidemiology, Taiwan Society of Preventive Medicine, Taiwan Society of Microbiology, Society of Public Health of ROC, Society of Cancer of ROC, Chinese Medical Association.
Honors and awards
1. Scholarship from Society of Microbiology of ROC, Yen Shi-Chung Award, 1983.
2. Scholarship from the Ministry of Education to study abroad, Taiwan, R.O.C., 1986-89.
3. Scholarship from the Fogarty International Center, National Institutes of Health, Program of International Training Grants 1989-92.
4. Education and Culture Award, Significant Contribution to the Scientific Education for the Public, from the Ministry of Education, Taiwan, 1993.
5. Research award, from the National Science Council, Taiwan, 1993, 1994, 1995, 1997, 1999 and 2000.
6. Secretary General, the First, Second and Third Taipei International AIDS Conferences, 1990, 1992 and 1994.
7. Candidate for the International Prince Mahidol Award from Thailand, nominated by the Department of Health, Executive Yuan, R.O.C., 1994.
8. Young Investigator Award, First Joint Annual Conference of the Society of Oncology, Taiwan, 1996.
9. Who’s Who in the World, 2001- 18th edition.
10. Who’s Who in Medicine and Healthcare, 2002 edition.
11. Who’s Who among Executives and Professionals, 2010 edition.
12. Scholarships from the National Science of Council of ROC for short-term training (2003).
13. Outstanding Research Award from National Science Council, 2008.
14. Outstanding alumnus, Fu-Xin Primary school, 2004.
15. Invited as a reviewer for the following grant applications: National Science Council (committee members on the Public Health and Environmental Sciences), University Grants of Hong Kong, Specific Region of China and Pfizer AIDS foundation.
16. Best Paper Award from the Urbani Foundation 2005 and 2007.
17. Award to Special contribution to harm reduction program, 2007 from Ministry of Health.
18. The Second Best Research Paper Award of the Chinese Medical Association Annual meeting, 2007.
19. The Best Research Paper Award of the Taipei City Hospital grants, 2007.
20. Outstanding alumnus (Academic achievement), National Yang-Ming University, 2009.
21. Associate Editor, BMJ-Infectious Disease (since 2008); BMJ-Research Note (since 2008).
18. Editorial board member: Chinese Journal of Medicine, The OpenHepatologyJournal (since 2008), Newsletter for Research on Applied Ethics (since 2000, in Chinese), Liver Cancer Review Letters (since 2009), World Journal Hepatology (2009-2013).
19. Ad hoc referee for the following journals, institutions and conference organizers:
Hepatology,
Lancet
AIDS Research and Human Retroviruses,
Blood
Journal of Hepatology
Journal of infectious Disease
American Journal of Pathology
Experimental Biology and Medicine
Taiwan J. Public Health
Jouranl of Chinese Society of Physiology
Acta Pharmacol Sin
Infection Genetic and Evolution
Retrovirology
International Journal of Drug Policy
Environmental Health Perspectives
the XIII, XIV, XV and XVI International AIDS Conferences;
the 6th and 7th International Conference on AIDS in Asia and Pacific (ICAAP);
the 4th IAS meeting
National Medical Research Council of Singapore
Hong Kong Department of Health
Welcome Trust
Chief Scientist Office, UK
Publication List
Referred papers: (*corresponding author)
1. Chen YM, Hu CP, Wong FH, et al. Circulating immune complexes in the sera and ascites of hepatocellular carcinoma patients. Chinese J. Micro. Immunol. 19:34-45, 1986.
2. Chen YM, Hu C, Chen P, et al. Nuclear antigens reacted with sera and ascites of hepatocellular carcinoma patients. Hepatology 8:547-552, 1988.
3. Matsuda Z, Chou MJ, Matsuda M, Huang JH, Chen YM, Redfield R, Mayer K, Essex M and Lee TH. Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome. Proc. Natl. Acad. Sci., USA 85: 6968-6972, 1988.
4. Chen YM, Lee TH, Samuel KP, Okayama A, Tachibana N, Miyoshi I, Papas TS, and Essex M. Antibody reactivity to different regions of human T-cell leukemia virus type-I (HTLV-I) gp61 in infected people. J Virol 63: 4952-4957, 1989.
5. Chen YM, Lee TH, Wiktor SZ, Shaw GM, Murphy EL, Blattner WA and Essex M. Type-specific antigens for serological discrimination of HTLV-I and II infection. Lancet 336: 1153-1155, 1990.
6. Chen YM, Gomez-Lucia E, Okayama A, Tachibana N, Lee TH, Mueller N and Essex M. The antibody profile of early HTLV-I infection. Lancet 336: 1214-1216, 1990.
7. Okayama A, Chen YM, Tachibana N, Shioiri S, Lee TH, Tsuda K and Essex M. High incidence of antibodies to HTLV-I tax in blood relatives of adult T-cell leukemia patients. J. Infect. Dis. 163: 47-52, 1991.
8. Chen YM, Okayama A, Lee TH, Tachibana N, Mueller N and Essex M. Sexual transmission of HTLV-I associated with the presence of the anti-tax antibody. Proc. Natl. Acad. Sci. USA 88: 1182-1186, 1991.
9. Chen YM and Essex M. Identification of a recombinant HTLV-II envelope protein with distinguishing reactivities to sera from HTLV-II carriers. AIDS Res. Hum. Retroviruses 7: 453-457,1991.
10. Chen YM, Zhang X-q, Dahl C, Samuel KP, Schooley RT, Essex M and Papas TS. Delineation of type-specific regions on human T-cell leukemia virus envelope glycoproteins. J. Immunol. 147: 2368-2376, 1991.
11. Chen YM*. Serological discrimination of HTLV-I and HTLV-II infection by recombinant protein-western blot assays. Biomed. Pharmacotheraphy 45:274, 1991.
12. Okayama A, Kober B, Chen YM, Allan J, Lee TH, Shioiri S, Tachibana N, Tsuda K, Mueller N, Mclane MF, Maayan S, Markink R, Orgad S and Essex M. Unusual pattern of antibodies to HTLV-I in family members of adult T-cell leukemia patients. Blood 78: 3323-3329, 1991.
13. Samuel KP, Hodge DR, Chen YM and Papas TS. Nef protein of the human immunodeficiency viruses (HIV-1 and HIV-2) and simian immunodeficiency virus (SIV) are structurally similar to leucine zipper transcriptional activation factors. AIDS Res. Hum. Retroviruses 7: 697-706, 1991.
14. Zhang X-q, Yang L, Ho DD, Kuritzkes D, Chen I, Chen YM and Schooley RT. HTLV-I and HTLV-II Specific antibody dependent cellular cytotoxicity: strain specificity and epitope mapping. J. Infect. Dis. 165: 805-812, 1992.
15. Maayan S, Dan M, Marlink R and Chen YM*. Exposure to Human Retroviruses HTLV-I, HTLV-II and HIV among Israeli IV drug abusers. Int. J. Epidemio. 21:995-997, 1992.
16. Whang-Peng J, Chen YM, Knutsen T, Zhao W-P and Tsai S. Chromosome studies in HTLV-I, II, and HIV-1, 2 cell lines infected in vivo and in vitro. JAIDS J. Acqui. Immun. Defic. Syndr. 6: 930-940, 1993.
17. Chen YM*, Jang Y-J, Kanki PJ, Wang J-J, Montali RJ, Samuel KP and Papas TS. Isolation and characterization of simian T-cell leukemia virus type II from New World monkeys. J. Virol. 68: 1149-1157, 1994.
18. Hodge DR, Chen YM and Samuel KP. Oligomeraization of the HIV-2 Nef Protein: mutational analysis of the heptad leucine repeat motif and cysteine residues. AIDS Res. Hum. Retroviruses 11: 65-79, 1995.
19. Chen YM. Taiwan's sex-workers have less than 1% infection. AIDS Analysis Asia 1: 2 1995.
20. Chang L-J, Chen YM, Chen, M-Y, Chou C-C, Twu SJ, Huang L-M. HIV 10 years later-where do we stand now? J Biomed Sci 2: 1-11, 1995.
21. Yao C, Wang W-W, Chung Y-M, Su Y-L, Liu C-Y and Chen YM*. Transfusion-acquired AIDS in Taiwan. J. Formos. Med. Assoc. 95: 51-55, 1996.
22. Chen YM*, Lin H-C and Chou P. A population-based epidemiological study of human T-cell leukemia virus type I infection in Kin-Hu, Kinmen. Int. J. Cancer 59: 569-573, 1996.
23. Yao C, Kao S-S, and Chen YM*. Cost-benefit analyses of the HIV-1 and HIV-1/HIV-2 screening program in blood donation centers in Taiwan. Chin. J. Public Health (Taipei), 15: 483-496, 1996.
24. Chang P, Liau M-Y, Yang C-M, Ho M-S, Lee C-H, Chen YM and Horng C-B. Cost analysis of establishing the capability of producing MMR, DTaP, HBV, and OPV vaccines in Taiwan. Chin. J. Public Health (Taipei), 15: 517-524, 1996.
25. Chen YM*, Chang L-Y, Fu C-Y and Chou P. A survey of knowledge, attitudes and practices (KAP) concerning AIDS among female sex workers from massage parlors in Taiwan. Chin. J. Public Health (Taipei), 16: 439-454, 1997.
26. Shieh B, Lee C-M, Su I-J, Chen YM and Li C. Molecular subtyping of the V3 loop sequences detected in HIV-1-positive patients at the National Cheng Kung University Hospital. Chinese J. Micro. Immunol. 30: 46-54, 1997.
27. Li C, Yan Y-P, Shieh B, Lee C-M, Lin R-Y, and Chen YM*. Analysis of the CKR5 allele in AIDS patients and female sex workers in Taiwan. J. Formos. Med. Assoc. 96: 979-984, 1997.
28. Chen YM*, Chen S-H, Chen J-Y and Osame M. Antibody reactivities to tumor-suppressor protein p53 and HTLV-I Tof, Rex and Tax in HTLV-I infected people with differing clinical status. Int. J. Cancer 71:196-202, 1997.
29. Chen Y-J, Shih L-S, Chang J-G, Whang-Peng J, and Chen YM*. Frequent detection of aberrant RNA transcripts of the CDKN2 gene in human gastric adenocarcinoma. Int. J. Cancer 71: 350-354, 1997.
30. Chen YM*, Yu PS, Lin C-C and Jen I. Surveys of HIV-1 HTLV-I and other sexually transmitted diseases among female sex workers in Taipei city and prefectures, Taiwan from 1993 to 1996. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol. 18: 299-303, 1998.
31. Chen YM*, Lee C-M, Lin R-Y, Chang H-J. Molecular epidemiology and Trends of HIV-1 Subtypes in Taiwan. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol. 19: 393-402, 1998.
32. Chen YM*, Shiu J-Y, Tzeng SJ, Li-Sun Shih, Yi-Jen Chen and Lui W-Y. Characterization of the glycine-N-methyltransferase-gene expression in human hepatocellular carcinoma. Int. J. Cancer 75: 787-793, 1998.
33. Chen Y-J, Shih L-S and Chen YM*. Quantitative analysis of CDKN2, p53 and retinoblastoma mRNA in human gastric carcinoma. Int J Oncol 13: 249-254, 1998.
34. Chen YM*, Lin R-H, Lee C-M, Fu C-Y, Chen S-C and Syu W-J. Decreasing levels of anti-Nef antibody correlate with increasing viral loads and AIDS disease progression. AIDS Res. Human Retroviruses 15: 43-50, 1999.
35. Chen YM*, Ting S-T, Lee C-M, W-T Liu, Pan W-H, TA Chang, Chou P. Community-based molecular epidemiology of human T-cell leukemia virus type I infection in Taiwan and Kinmen: Implication of the origin of the cosmopolitan subtype in North East Asia. AIDS Res Human Retroviruses 15: 229-237, 1999.
36. Liou YM, Chou P, Chen YM*. Genotypic Analysis of HCV infection in Kinmen. J. Microbiol. Immunol. Infect. 33: 63-68, 2000.
37. Chen YM*, Chen LY, Wong FH, Lee CM, Chang TJ, Yang-Feng TL. Genomic structure, expression and chromosomal localization of the human glycine N-methyltransferase gene. Genomics 66: 43-47, 2000.
38. Chen YM*, Huang KL, Jen I, Chen SC, Liu YC, Chuang YC, Wong JC, Tsai JJ. Temporal trends and molecular epidemiology of HIV-1 Subtypes in Taiwan from 1988 to 1998. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol. 26: 274-282, 2001.
39. Chen YM*, Rey WY, Lan YC, Lai SF, Huang YC, Wu SI, Liu TT, Hsiao KJ. Antibody reactivity to HIV-1 Vpu in HIV-1/AIDS patients on highly active antiretroviral therapy. J. Biomed. Sci. 10: 266-275, 2003.
40. Yang MH, Chen YM, Kuo BI, Wang KY. Quality of life and related factors for people living with HIV/AIDS in Northern Taiwan. J. Nurs. Res. 11: 217-26, 2003.
41. Liu HH, Chen KH, Shih YP, Lui WY, Wong FH, Chen YM*. Characterization of reduced expression of glycine N-methyltransferase in the cancerous hepatic tissues using two newly developed monoclonal antibodies. J. Biomed. Sci. 10: 87-97, 2003.