Pharmaceutics Second Exam

• Pharmaceutics I
• Name: ______

Pharmaceutics Second Exam

October 25 2002

(40 Q * 5=200)

11:00-12:00P.M.

Samaan

Please show all your works

Name: ______

Questions 1-2 are related to the following prescription

Rx

Sodium45 mEq[23]

Potassium20 mEq[39]

Chloride35 mEq[35.5]

Citrate30 mEq[189]

Waterad1000 mL

1-Calculate the equivalent quantity of chloride in g.

A-124

B- 158

C- 1850

D- None of the above.

2-Calculate the equivalent quantity of Citrate in g.

A-124

B- 158

C- 1850

D- None of the above.

Use the following prescription for questions 3-4

Rx

- Oxytetracycline Hydrochloride 0.5% [497, 2]

Tetracaine Hydrochloride Solution [1:1000] 30.0 mL

Sodium Chloride q.s.

Purified Waterad60.0 mL

Sig: For the eye

Make solution isotonic

Tetracaine Hydrochloride Solution [1:1000] is already isotonic.

3- What is the % strength of TETRACAINE HYDROCHLORIDE in the final product?

A- 0.05 %

B- 0.15%

C- 1.5%

D- None of the above.

4- Using the “D” method, how many g. of Na Cl should be used in preparing the prescription?

A- 0.18 g

B- 1.8 g

C- 18.0

D- None of the above.

Questions 5-8 are related to the following prescription

Rx

NaHCO35%[84, 2]

Sterile water for injectionad500

5-Calculate the mEqmL-1.

A-0.5952

B- 5.952

C- 59.52

D- None of the above.

6-Calculate the total mEq.

A-2.9762

B- 29.7619

C- 297.619

D- None of the above.

7-Calculate the Osmolarity.

A-1.19

B- 11.9

C- 119

D- None of the above.

8-Calculate the Molarity.

A-0.5952

B- 5.952

C- 59.52

D- None of the above.

9-A patient has a sodium deficit of 154 mEq. How many mL of N.S.S. should be administered to replace the deficit?

A-10.0

B- 110.0

C- 1000.0

D- None of the above.

10-Manufacturer’s directions call for the addition of 90 mL of water to constitute a 120 mL container of cefaclor to yield strength of 250 mg5mL-1. If by mistake a 60 mL of water is added in constituting the product, calculate the resultant concentration in mg5mL-1?

A- 50

B- 29.13

C- 213.92

D- None of the above.

11-A patient receives 3 Liters of 125 mg of potassium acetate [98] per 100 mL. How many mEq of K+ does the patient receive?

A-38.26

B- 12.98

C- 4.76

D- None of the above.

12-A patient receives 3 Liters of 21 mg of magnesium acetate [142] per 100 mL. How many mEq of Mg++ does the patient receive?

A-0.887

B- 8.870

C- 88.70

D- None of the above.

13-Calculate the osmolarity, in mOsmol. per mL, of parenteral solution containing 2 mEqmL-1 of potassium acetate [98].

A-0.4

B- 4.0

C- 40.0

D- None of the above.

14-What is the drug dose for a child weighing 10 kg & 55 cm tall, if the drug dose is 100 mgm-2?

A- 14.92 mg

B- 24.92 mg

C- 34.92mg

D- None of the above.

15-Human serum osmolality could be calculated with the following equations EXCEPT:

A-1.86 Na + (Blood sugar/18) + (BUN/2.8)+ 15

B- 2 Na + (Blood sugar/20) + (BUN/3)

C- 2 Na + 100

D- None of the above.

16-Five mL of Lithium citrate (C6H5Li3O7, 210, 4) syrup contains the equivalent of 8 mEq of Li+. Calculate the equivalent, in mg, of Lithium carbonate (Li2CO3, 74, 3) in 5 mL dose of the syrup.

A-296

B- 567

C- 957

D- None of the above.

17-A physician wishes to administer 1,200,000 Units of penicillin G potassium every 4 hours. If 1 unit of penicillin G potassium (C16H17KO4S, 372) = 0.6 mg, how many mEq of K+ will the patient receive in 24 hours?

A-1.161

B- 11.61

C- 116.1

D- None of the above.

Use the following solution for Questions 18-20:

A 147 mL of 10% (w/v) of Calcium chloride, 2 H2O [147, 3] solution.

18-How many millimoles in the above solution?

A.100

B- 200

C- 300

D- None of the above.

19- How many milliequivalents in the above solution?

A.100

B- 200

C- 300

D- None of the above.

20- How many milliosmole in the above solution?

A.100

B- 200

C- 300

D- None of the above.

21-What is the freezing point of 0.1% of Zinc Sulfate solution?

A. -0.52oC

B- -1.86oC

C- -2.60oC

D- None of the above.

Determine if the following products are hypotonic, isotonic, or hypertonic:

22- An ophthalmic solution containing 40 mgmL-1 of Cromolyn sodium [512, 2] in water.

A- Hypotonic

B- Iso-tonic

C- Hypertonic

D- None of the above.

23- A parenteral infusion containing 5 % (w/v) of Mannitol [182, 1].

A- Hypotonic

B- Iso-tonic

C- Hypertonic

D- None of the above.

24-What is the medical use of Mannitol?

A- Diuretic osmotic

B- Iso-tonic

C- Hypotonic

D- None of the above.

25- A Fleet enema containing 19 g of Sodium biphosphate monobasic [120, 2] & 7 g of Sodium phosphate dibasic [142, 3] in 118 mL of aqueous solution.

A- Diuretic osmotic

B- Iso-tonic

C- Hypotonic

D- None of the above.

26- A hypotonic parenteral product is:

A-Half-normal saline solution

B-Normal saline solution

C-D5W

D- None of the above.

27- A patient has a prescription for 32 mEq KCl P.O. The pharmacist has 600 mg KCl controlled-release tablets. How many tablets does the patient need to take each day to provide this dose?

A-Two tablets

B-Three tablets

C-Four tablets

D- None of the above.

28- One Mole of Boric acid [61.8, 1] has the same osmotic pressure as one Mole of calcium Chloride [111, 3].

A. The statement is true

B. The statement is false.

29- A 20- mL vial of Sodium chloride [58.5, 2] solution was diluted to 1 Liter with sterile distilled water. The concentration (w/v) of NaCl in the finished product was 0.585 %. What was the concentration, in mEq? mL-1 of the original solution?

A.1.25

B- 2.5

C- 5.0

D- None of the above.

For questions 30-33 use the following prescription

Rx

Ephedrine Sulfate 0.5% [429, 3]

Tetracaine Hydrochloride 0.5% [301, 2]

Dextroseq.s. [180, 1]

Purified Waterad30

Make isotonic nasal spray.

30- Using the “E” method, how many g. of dextrose should be used in preparing the prescription?

A-0.1175

B-1.1750

C-11.750

D- None of the above.

31- Using the “V-Value” method, how many mL of water and how many mL of 5% dextrose should be used in preparing the prescription?

A-6.5012, 23.4987

B-23.4987, 6.5012

C-15.0, 15.0

D- None of the above.

32- Using the “D” method, how many g. of dextrose should be used in preparing the prescription?

A-0.1175

B-1.1750

C-11.750

D- None of the above.

33- If Dextrose is not available, how many g of boric acid should be used in preparing this prescription?

A-5.9086

B-0.5181

C-0.4034

D- None of the above.

1-34-All isotonic solutions are iso-osmotic, and all iso-osmotic solutions are iso-tonic.

A.The first statement is true and the second statement is false.

B. The first statement is false, and the second statement is true

C. Both statements are false.

1. Both statements are true.

Use the following prescription for questions 35-37

Rx

Sol. Silver Nitrate 0.5%15[170, 2]

Make isotonic sol.

35-How many g. of potassium nitrate [101, 2] should be used to make the prescription iso-tonic?

A-0.19

B-1.90

C-7.90

D- None of the above.

36- If only N.S.S. is available, how many mL of N.S.S. should be used to make the prescription iso-tonic?

A-29.52

B-2.952

C-0.295

D- None of the above.

37-How many mL of H2O would make 0.075 g of Silver Nitrate iso-tonic?

A-0.04455

B-0.2353

C-2.839

D- None of the above.

38-The molecular weight of Lithium carbonate is 73.89. How many mEq of lithium are there in a 300 mg tablet?

A-1.24

B-2.46

C-8.12

D- None of the above.

Use the following prescription for Questions39-40:

Rx

Dextrose Anhydrous 2.5% [180, 1]

Boric acid q.s.[61.8, 1]

Sterile Water for injection ad 1000 mL

Make the injection isotonic for intravenous administration.

39- Using the “D” method, how many g of Boric acid should be used in compounding this prescription?

A-17.27

B-8.68

C-5.91

D- None of the above.

40-Which of the following substances is a weak electrolyte?

A-Dextrose

B-Boric acid

C-Sodium chloride

D- None of the above.

• If 10 mL of a Nitroglycerin Injection (5 mg of nitroglycerin per mL) is added to make a liter of D5W intravenous fluid, what is the % strength (W/V) of nitroglycerin in the final product?

• A- 0.005%
• B- 0.05%
• C- 0.5%
• None of the above.

• A pharmacist has a solution of KCl (74.5, 2) labeled 3 mEq per 5 mL. Express this solution in a mMole/dL concentration.

• A- 3 mMoledL-1
• B- 30mMoledL-1
• C- 60mMoledL-1
• None of the above.

• Questions 13-15 belong to the following prescription
• RX
• Dipivefrin Hydrochloride 1/2%[388, 2]
• Tetracaine Hydrochloride Solution [1:1000] 30.0 mL[301, 2]
• Sodium Chloride q.s.
• Purified Water ad 100 mL
• Make isotonic solution
• Sig.Tetracaine hydrochloride Solution is already isotonic.

• Using the “D” method, how many mL of N.S.S. should be used in preparing the prescription?

• A- 0.4583mL
• B- 0.9090mL
• C- 88.147mL
• None of the above.

• If NaCl is not available, how many g of KNO3 can be used to prepare the above prescription?

• A- 0.52g
• 6.2747 g
• 15.6869 g
• None of the above.

• Using the “V” method, how many mL of N.S.S. should be used in preparing the prescription?

• A- 0.4583mL
• B- 0.9090mL
• C- 88.147mL
• None of the above.
• How many grams of KNO3 [101, 2] should be added to 400 mL of distilled water to make KNO3 solution isotonic?

• A- 0.52g
• 6.2747 g
• 15.6869 g
• None of the above.

• Rx
• Sol. Silver Nitrate 0.5%15[170, 2]
• Make isotonic sol.

• Ifonly N.S.S. is available, how many mL of N.S.S. should be used to make the prescription iso-tonic?

• 29.52
• 2.952
• 0.295
• None of the above.

• If one hundred (100) mL of blood plasma normally contains 3 mg % of Mg++ [24, 1]. Express this concentration in term of mEq per liter.

• 0.055 mEqL-1
• B- 0.25mEqL-1
• C- 2.5mEqL-1
• None of the above.

• A hospital medication order calls for addition of 20 mEq of NaCl to one liter of Mannitol [182, 1] injection. How many mL of N.S.S. should be used?

• A- 13.039 mL
• 130.039 mL
• 489.577 mL
• None of the above.

• The Na+ concentration in normal healthy human serum in mMoleL-1 is:

• 98-108 mMoleL-1
• 2.5-4.5 mMoleL-1
• 133-146 mMoleL-1
• None of the above.

• When serum Osmolarity increases, the patient feel thirsty due to an increase in one of the following hormone:

• HDA
• ADH
• AHD
• None of the above.

• Which of the following equation is used to determine the serum Osmolarity?

• 18 Na + Blood sugar + BUN + 5
• 28
• 1.86 Na + Blood sugar + BUN + 5
• 2.8
• 2.8 Na + Blood sugar + BUN + 10
• 2.8
• None of the above.

• The normal range of human Osmolarity is:

• 282-288 mOsmol kg-1
• 294-298 mOsmol kg-1
• 299-333mOsmol kg-1
• None of the above.

• Lactulose and cephulac is used to treat which of the following condition:

• Osmotic diuretic
• Schistosomiasis
• Hepatic encephalopathy
• None of the above.

• The freezing point of 0.5 Mole of Mannitol [182, 1] is:

• -1.86oC
• -1.86oF
• -0.93oC
• None of the above.

• Adding human RBC’s to a hypertonic solution will leads to:

• Hemolysis
• Cremation
• Crenation
• None of the above.

• Rx
• Ephedrine Sulfate 0.5% [429, 3]
• Tetracaine Hydrochloride 0.5% [301, 2]
• Dextroseq.s. [180, 1]
• Purified Waterad30
• Make isotonic nasal spray.

• Using the “V-Value” method, how many mL of water and how many mL of 5% dextrose should be used in preparing the prescription?

• 6.5012, 23.4987
• 23.4987, 6.5012
• 15.0, 15.0
• None of the above.

• All isotonic solutions are iso-osmotic, and all iso-osmotic solutions are iso-tonic.

• The first statement is true and the second statement is false.
• The first statement is false, and the second statement is true
• Both statements are false.
• Both statements are true.

• A patient has been receiving 0.5 g tablet of KCl twice a day. The tablets upset his stomach. What would be the dose if he changed to a liquid dosage form containing 134 mEq of K+ per 100 mL?

• 10 mL
• 20 mL
• 30 mL
• None of the above.

• A physician orders 20 mL of 10% Magnesium Sulfate [M.W. 120] to be given as an anticonvulsant. How many mOsmol. will the patient receive?

• 16.66 mOsmol
• 33.33 mOsmol
• 50 mOsmol
• None of the above.

• What are the total mOsmol provided by a Liter of D5W?

• 110.975 mOsmol
• 177.974 mOsmol
• 277.778 mOsmol
• None of the above.

• How many mEq of calcium gluconate are in a Liter of 10% Calcium gluconate M.W. is 430?

• 1000 mEq
• 2000 mEq
• 3000 mEq
• None of the above.

• How many mOsmol of calcium gluconate arein a Liter of 10% Calcium gluconate?

• 1000 mOsmol
• 2000 mOsmol
• 3000 mOsmol
• None of the above.

• How many mMol of calcium gluconate are in a Liter of 10% Calcium gluconate ?

• 1.97 mMol
• 2.32 mMol
• 23.2 mMol
• None of the above.

• An order calls for 500 mL of ZnSO4 to be made so that it contains 10 mEq of Zn++ in a tablespoonful. How many g. of ZnSO4 are required?

• 48.0 g
• 84.0 g
• 288.0 g
• None of the above.

• In normal healthy human serum K+ ranges ______mMolL-1

• 98-109
• 138-146
• 3.7-5.3
• 2.25-2.65
• If two solutions have the same osmotic pressure, they will have the same:

• Vapor pressure
• Freezing point
• Boiling point
• All of the above.

• 1 M of Boric acid solution [61.8], has the same osmotic pressure as 1 N of Sodium Chloride solution [58.5].

• True
• False

• When a patient is treated for systemic encephalitis with Lactulose orally, which of the following Lab. result will be affected by the treatment?

• K+ serum level
• Na+ serum level
• NH+3 serum level
• None of the above.

• What is the percentage of KCl, which will be isotonic with RBC?

• 0.9%
• 1.15%
• 4.5%
• None of the above.

• What is the percentage of Boric acid, which will be isotonic with RBC?

• 0.9%
• 1.15%
• 4.5%
• None of the above.

• What is the maximum percentage of any suspension, which could be used in TPN?

• 0.0%
• 1.15%
• 4.5%
• None of the above.

• All isotonic solution is iso-osmotic, but not all the iso-osmotic solution is isotonic.

• The first statement is true, and the second statement is true.
• The first statement is true, and the second statement is false.
• The first statement is false, and the second statement is true.
• None of the above.

• Questions # 51-54 are related to the following Rx.
• Rx
• Epinephrine1.0%
• Chlorobutanol0.5%
• NaClq.s.
• Sterile Water for injectionad15.0 mL
• Make isotonic sol.

• How many grams of epinephrine bitartrate [M.W. 333,2]] should be used to obtain the amount of epinephrine [M.W. 183] needed in preparing in the prescription?

• 0.2729 g.
• 2.729 g
• 0.9272
• None of the above

• Starting with epinephrine bitartrate and using the “E” method, how many mg. of NaCl should be used in preparing the prescription?

• 32.1 mg
• 42.1 mg
• 73.29 mg
• None of the above

• Starting with epinephrine bitartrate, and using the “V” method, how many mL. of NSS should be used in preparing the prescription?

• 6.85 mL
• 8.15 mL
• 7.85 mL
• None of the above.

• Starting with epinephrine bitartrate, and using the “D” method, how many mg. of NaCl should be used in preparing the prescription?

• 32.1 mg
• 42.1 mg
• 52.1 mg
• None of the above
• The freezing point of a molal solution of nonelectrolyte is –1.86 oC. What is the freezing point of a 0.1 % solution of zinc sulfate, 7 H2O?

• 0.0090 oC
• – 0.0260 oC
• – 0.2600 oC
• None of the above.

• Rx
• Oxytetracycline HCl0.5%[497,2]
• Tetracaine HCl sol. 2%10 mL
• Boric Acidq.s.
• Purified Waterad30 mL
• Sig. fir the eye.

• The 2% solution of tetracaine HCl is already isotonic. How many mg of Boric acid should be used to compound the prescription?

• 312.43 mg
• 624.86 mg
• 936.14 mg
• None of the above

• Rx
• Atropine Sulfate 1.0%[695;3]
• Boric acid q.s.
• Purified Waterad 30.0 mL
• Make isotonic Sol.

• How many ml of 5%boric acid should be used to obtain the amount of boric acid needed in the prescription?

• 3.99 mL
• 6.99 mL
• 8.99 mL
• 12.99 mL

• Rx
• Tetracaine HCl0.5%[301,2]
• Sol. Epinephrine bitartrate 1:100010.0 [333,2]
• Boric acidq.s.
• Purified Waterad.30.0
• Make isotonic Sol.
• Sig. Eye drops

• The solution of epinephrine bitartrate (1:1000) is already isotonic. Using the V-value method, How many mL. of 5%boric acid should be used in compounding this prescription?

• 4.8 mL
• 5.8 mL
• 6.8 mL
• 9.8 mL

• Using the freezing point depression( D) value for pilocarpine hydrochloride [245,2]. What will be the % concentration of pilocarpine hydrochloride that would be isotonic with lacrimal fluid?

• 3.8 %
• 4.8 %
• 5.8 %
• 6.8 %

• The questions from 10-16 are related to the following prescription:
• Rx
• Naphazoline HCl0.02% [247,2]
• Zinc sulfate0.25%
• Purified waterqs30 mL
• Mft Isotonic solution

• How many mg of Naphazoline HCl are required to fill up the above prescription?

• 6 mg
• 60 mg
• 600 mg
• None of the above.

• How many mg of NaCl are required to make the above prescription isotonic?

• 270 mg
• 257 mg
• 344 mg
• None of the above.

• Using the V-value method, how many mL of NSS should be used to fill up the above prescription?

• 28.53 mL
• 18.53 mL
• 8.53 mL
• None of the above.

• Using the Freezing point method, how many mg of NaCl should be used to fill up the above prescription?
• 270 mg
• 257 mg
• 344 mg
• None of the above.
• If Boric acid will be used instead of NaCl, how many mg of Boric are required to fill up the above prescription?
• 540 mg
• 508 mg
• 494 mg
• None of the above.

• What is the percentage of Naphazoline HCl will be isotonic in water?

• 10.56 %
• 5.28 %
• 2.14 %
• None of the above.

• What is the percentage of ZnSO4 will be isotonic in water?

• 10.56 %
• 5.75 %
• 2.14 %
• None of the above.

• The freezing point of 10% solution of Zinc Chloride [136,3] is:

• -0.2556 oC
• -3.556 oC
• -0.5256 oC
• None of the above.

• The Boric acid equivalency “E” for Lithium carbonate [74,3] is:
• 0.6668
• 0.8828
• 2.171
• None of the above.

• In normal healthy human serum Na+ ranges ______mMolL-1

• 98-109
• 138-146
• 3.7-5.3
• 2.25-2.65

• 17.277 gL-1 Boric acid solution is iso-osmotic with both blood & lacrimal fluid,but only isotonic with lacrimal fluid.

• First statement is false and second statement is true.
• First statement is true and second statement is false.
• Both statements are true.
• Both statements are false.

• In case of administration of Lactulose or Cephulac to hepatic-encephalopathy patient, which of the following lab. result will be affected?.
• The blood sodium level
• The blood potassium level
• The blood chloride level
• The blood ammonia level.

• 22- RxSol Silver Nitrate0.5%15 [170,2]
• Make isoton. Sol.
• Sig. For the eyes
• How many mg. of NaNO3 could be used to make the prescription isotonic?

• 140.5 mg
• 150.5 mg
• 160.5 mg
• None of the above.

• Rx
• Ephedrine Sulfate1%[429,3]
• Chlorobutanol0.5%
• Purified Waterad100.0
• Make isoton.sol. and buffer to pH 6.5

• You have on hand an isotonic buffered solution, pH 6.5. How many mL of purified water and how many mL of buffered solution should be used to in compounding the prescription?

• 28.53, 71.47 mL
• 18.53, 81.47 mL
• 50.41, 49.58 mL
• None of the above.

• Rx
• Monobasic sodium phosphate, anhydrous5.6[120,2]
• Dibasic sodium phosphate, anhydrous2.84[142,3]
• Sodium Chlorideq.s.
• Purified Waterad1000

• How many g. of NaCl. Should be used in preparing the solution?
• 4.58 g
• 5.86 g
• 9.36 g
• None of the above.

• Isotonic Sodium Chloride Solution contains 0.9% of Sodium Chloride. If Sodium Chloride equivalent of Boric Acid is 0.52, what is the percentage strength of an isotonic solution of Boric Acid?

• 1.73%
• 17.3%
• 173%
• None of the above

• If the freezing depression of a 10 % aqueous solution of a new chemical salt xy is - 0.0904 oC, and the salt dissociation constant is 1.4. What is the Molecular weight of new compound?

• 500
• 750
• 1000
• None of the above

• What is the KNO3 Equivalency for Lithium carbonate [74,3]?

• 0.9714
• 1.9714
• 2.9714
• None of the above

• The freezing point depression( D) value for 1% solution of pilocarpine hydrochloride is = - 0.14o C. What will be the % concentration of pilocarpine hydrochloride that would be isotonic with lacrimal fluid?

• 1.714%
• 2.714%
• 3.714%
• None of the above

• All the following questions 29-35 are related to the following prescription:-

• Rx
• Cocaine HCl0.25%[340,2]
• Mft. Isotonic ophthalmic solution30 mL
• Sig:i-ii gtts os qid

• How many mg of NaCl are required to make the above prescription isotonic?

• 270 mg
• 257 mg
• 344 mg
• None of the above.

• If Boric acid will be used instead of NaCl, how many mg of Boric are required to fill up the above prescription?
• 540 mg
• 508 mg
• 494 mg
• None of the above.

• Using the F.P. method, how much further would you need to lower the freezing point to make it isotonic?

• -0.52 oC
• -0.024 oC
• -0.495 oC
• None of the above.

• What is the percentage of cocaine HCl will be isotonic?

• 10.56 %
• 5.28 %
• 2.14 %
• None of the above.

• Using the “V” value method, what is the volume (mL) of distilled water needed to be added to the Cocaine HCl to make it isotonic?

• 1.15 mL
• 1.44 mL
• 3.48 mL
• None of the above.

• Using the “V” value method, what is the volume (mL) of NSS needed to be added to the Cocaine HCl solution to make the prescription isotonic?

• 30.0 mL
• 29.52 mL
• 28.56 mL
• None of the above.

• What direction would you put on the label?

• Use as directed
• one to two drops in each eye four times daily
• one to two drops in the left eye four times daily
• None of the above.

• In normal healthy human serum K+ ranges ______mMolL-1

• 98-109
• 138-146
• 3.7-5.3
• 2.25-2.65

• When serum Osmolarity increase, the patient in the beginning feels thirsty due to:

• Thirst has no relation to ADH.
• There will be no change in ADH
• A decrease in ADH
• An increase in ADH

• If two solutions have the same osmotic pressure, they will have the same:

• Vapor pressure
• Freezing point
• Boiling point
• All of the above.

• 1 M of Boric acid solution [61.8], has the same osmotic pressure as 1 N of Sodium Chloride solution [58.5].

• True
• False

• RX
• Dipivefrin Hydrochloride 1/2%[388, 2]
• Tetracaine Hydrochloride Solution [1:1000] 30.0 mL[301, 2]
• Sodium Chloride q.s.
• Purified Water ad 100 mL
• Make isotonic solution
• Sig. Use in the eye as directed
• Tetracaine Hydrochloride Solution [1:1000] is already isotonic.
• Using the “D” method, how many mL of N.S.S. should be used in preparing the prescription?

• A- 0.4583mL
• B- 0.9090mL
• C- 88.147mL
• None of the above.

• How many g. of KNO3 [101, 2] should be added to 400 mL of water to make isotonic KNO3 solution?

• A- 0.52g
• g
• 15.6869 g
• None of the above.

• 3- Rx Sol. Silver Nitrate 0.5%15[170, 2]
• Make isotonic sol.

• Using the “D” method, how many mL of 5% Boric acid. should be used in preparing the prescription?

• A- 0.4583mL
• B- 0.9090mL
• C- 88.147mL
• None of the above.

• Which of the following equation is used to determine the serum Osmolarity?

• 18 Na + Blood sugar + BUN + 5
• 28
• 1.86 Na + Blood sugar + BUN + 5
• 2.8
• 2.8 Na + Blood sugar + BUN + 10
• 2.8
• None of the above.

• The normal range of human Osmolarity is:

• 282-288 mOsmol kg-1
• 294-298 mOsmol kg-1
• 299-333mOsmol kg-1
• None of the above.

• Lactulose and cephulac is used to treat which of the following condition:

• Osmotic diuretic
• Schistosomiasis
• Hepatic encephalopathy
• None of the above.

• The freezing point of 0.5 Mole of Mannitol [182, 1] is:

• -1.86oC
• -1.86oF
• -0.93oC
• None of the above.

• Adding human RBC’s to a hypertonic solution will leads to:

• Hemolysis
• Cremation
• Crenation
• None of the above.
• Rx
• Ephedrine Sulfate 0.5% [429, 3]
• Tetracaine Hydrochloride 0.5% [301, 2]
• Dextroseq.s. [180, 1]
• Purified Waterad30
• Make isotonic nasal spray.

• Using the “V-Value” method, how many mL of water and how many mL of 5% dextrose should be used in preparing the prescription?

• 6.5012, 23.4987
• 23.4987, 6.5012
• 15.0, 15.0
• None of the above.

• All isotonic solutions are iso-osmotic, and all iso-osmotic solutions are iso-tonic.

• The first statement is true and the second statement is false.
• The first statement is false, and the second statement is true
• Both statements are false.
• Both statements are true.

• Rx
• Ephedrine Sulfate 0.5% [429, 3]
• Tetracaine Hydrochloride 0.5% [301, 2]
• Dextroseq.s. [180, 1]
• Purified Waterad30
• Make isotonic nasal spray.

• Using the “V-Value” method, how many mL of water and how many mL of 5% dextrose should be used in preparing the prescription?

• 6.5012, 23.4987
• 23.4987, 6.5012
• 15.0, 15.0
• None of the above.

• If Dextrose is not available, how many g of boric acid should be used in preparing this prescription?

• 5.9086
• 2.5181
• 0.4034
• None of the above.

• Use the following prescription for questions 6-9

• Rx
• Silver Nitrategr ivss[170, 2]
• Dist aq.Ad30 mL
• Make isotonic sol.
• How many g. of sodium nitrate should be used to make the prescription iso-tonic?

• 0.198
• 1.98
• 7.98
• None of the above.

• How many mEq of lithium are there in a 300 mg tablet of Lithium Carbonate [73.89, 3]?

• 1.24
• 2.46
• 8.12
• None of the above.
• Which of the following substances is a weak electrolyte?

• Dextrose
• Boric acid
• Sodium chloride
• Zinc Sulfate

• What is the medical use of Mannitol?

• Osmotic Diuretic
• Iso-tonic
• Hypotonic
• None of the above.

• A patient has a prescription for 32 mEq KCl P.O.