Webquest 16 DNA

Name______

Part 2 – RNA, Transcription, Translation RNA

Go to http://www.dnaftb.org/dnaftb/21/concept/index.html

Read the text and answer the following questions

1. Where is RNA commonly found? ______

2. Describe what is meant by the “central dogma” in biology.

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3. Name the 3 types of RNA and the general roles they play in the making of protein.

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Click on the animation button below. Step through the animation and compare and contrast the structure of RNA to DNA. Use the Venn diagram to compare and contrast. Then do a sketch of an RNA molecule (at least 10 nucleotides long using the all the appropriate bases at least twice).

DNA

RNA

RNA Sketch (at least 10 nucleotides long with appropriate nitrogen bases)

Transcription (DNA  RNA)

Go to http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/transcription.swf

Answer the following questions as you move through the animation of Transcription

Before clicking

1. The diagram represents what type of molecule? ______

Click once

2. What type of molecule is the RNA polymerase? ______

Click again

3. What function does the RNA polymerase have? ______

4. Where in the cell do you think this is taking place? ______

5. Explain how the mRNA molecule forms.

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Go to the DNAi website: http://www.dnai.org/a/index.html

Click on “Copying the Code” at the bottom of the page, then click on “putting it together” at the top of the new page. Select “transcription”. Watch the animation

1. What does the blue molecule do? ______

2. What is the yellow chain? ______

3. What is T replaced with in RNA? ______

Translation (mRNA to protein)

Go to http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/translation.swf

Answer the following questions as you move through the animation of Translation

Before clicking

1.  The diagram represents what type of molecule? ______

Click once

2. Where in cell in this taking place? ______

Click again

3. What type of molecule is the tRNA (transfer RNA) bringing to the mRNA? ______

4. Explain (in terms of nitrogen bases) how the tRNA docks on the mRNA ?

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Click until the end watching the process of translation

5. As the tRNAs dock on the mRNA bringing amino acids with them what type of molecule is created

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Start the animation over

6. What are the 3 nitrogen bases on the tRNA carrying the amino acid “Met”? ______

7. What are the 3 nitrogen bases on the mRNA that the “Met”-tRNA docks upon? ______

8. Check out the next tRNA with its 3 nitrogen bases and see where it docks on the mRNA.

Can you detect a pattern. If there are 20 amino acids then what is the minimum number of tRNAs that must exist.

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Go to the DNA website: http://www.dnai.org/a/index.html

Click on “Reading the Code” at the bottom of the page, then click on “putting it together” at the top of the new page. Select “interactive”.

9. Practice translation using the computer animation, and write down the final amino acid sequence here:

Part 3

Source http://www.lz95.net/lzhs/science/jhawkins/bioi/spring/ch12webquest.pdf

Access the following site: http://gslc.genetics.utah.edu/

Click on “The Basics and Beyond”

Click on “Tour of the Basics” and complete the online activity

Click on “What is DNA?” (Begin & continue to click “Next”)

1. What is the DNA helix made up of? ______

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2 DNA is made up of letters-words-sentences; what is the function of the sentences?

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Click on “What is a gene?” (Begin & continue to click “Next”)

3. What is a gene? ______

4. Give 2 examples produced by genes?

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5. What results when the instructions from a gene are changed?

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Click on “What is a chromosome?” (Begin & continue to click “Next”)

6 Chromosomes are made up of 2 things?

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7. How many chromosomes do mosquitoes have?______

Click on “What is a protein?” (Begin & continue to click “Next”)

8. What is a protein?______

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9. How is an individual protein made?______

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10. Where are the proteins assembled?______

Click on “What is heredity?” (Begin & continue to click “Next”)

11. Where do your traits come from?______

12. What is a zygote?______

Click on “What is a trait?” (Begin & continue to click “Next”)

13. Give 2 examples of different types of traits?

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14. How are traits defined?______

16. What is a complex trait?______

Click on the Back and Return to the Basics and Beyond,

Click on “Discover How Proteins Function”

17. How are proteins shaped?

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18. Give 2 examples of how scientists determine the function of proteins

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19. What is a motif?______

Access the following site: http://www.dnaftb.org/dnaftb/

Under the heading “Molecules of Genetics,” Click on topic #15

Read the information provided

Click on “Animation” (at the bottom) for the lesson (Begin reading & continue to click

Next)

20. Who is Fredrick Miescher?______

21. What are 2 nucleic acids ______and where are they found?______

22 What did Phoebus Levene study?______