Summary of information received in response to the data gathering initiative on certain substituted diphenylamine substances (2012)

Purpose

To increase transparency and to facilitate access to information on substances in commerce in Canada, the government of Canada is providing a summary of the information received in response to thedata gathering on certain substituted diphenylamine substances. The data gathering was conductedunder the Substance Groupings Initiative of the second phase of the Chemicals Management Plan (CMP),to support risk assessment and risk management activities for these substances.

This document offers an overview of theinformation gathered under this initiative and includes general information on what was received including the type of submission, the main substances reported, activities, substance functions and commercial uses reported, the main industrial sectors involved, and the scientific studies reported for each substance. To complement this summary, a compilation of the non-confidential information received is available in Excel format, and provides a more complete dataset.Both documents refer toresponses to theNotice with respect to certain substituted diphenylamine substances, which was published in the Canada Gazette in June 2012, as well as information provided on a voluntary basis.

Important information about this summary:

  • The information provided under the Notice was collected for the 2011 calendar year.
  • Some information gathered under this initiative was considered Confidential Business Information (CBI)[1] by the submitters. While this summary and the Excel compilation were prepared using the full dataset (including CBI), CBI was masked in both documents prior to publication.Masking refers to the process whereby the information is used in such a manner so that CBI is not revealed. This can be done by, for example, aggregating data or by providing quantity ranges. For instances when masking could not adequately provide protection, CBI data elements were removed from the final version.
  • Sensitive information,[2] such as names of submitters, names of their customers and suppliers, or any information that could identify a submitter, was also not included.
  • The s.71 Notice targeted specific information to address specific data needs identified for the substances. As such, the information gathered and reported here does not represent the entire range of commercial activities in Canada with the substances. The specific reporting requirements, exclusions and definitions applicable to the Notice can be found in Schedule 2 and Schedule 3 to the Notice.
  • Certain submitters chose to provide information that was not legally required under the Notice. This voluntary information is included here.

It should be noted that this document does not include an assessment of the potential risks these substances may represent for the environment or the health of Canadians. Screening assessment reports for Substituted Diphenylamine substances can be found on the Substituted DiphenylamineSubstance Groupingwebpage.

Background

Canada’s Chemicals Management Plan (CMP) is jointly administered by Environment and Climate Change Canada and Health Canada under the CEPA and aims at reducing the risks posed by substances to Canadians and their environment. Under the CMP, the government gathers available information to support risk assessment and risk management decisions. When information needs continue to exist, a variety of approaches can be used, such as information-gathering requirements issued under the CEPA, voluntary information-gathering initiatives, research, monitoring and surveillance as well as international cooperation.

On October 8, 2011 an announcement was published in the Canada Gazette, setting how the Government of Canada planned to address approximately 500 substances in nine groups that had been selected as the next round of priorities under the second phase of the CMP.

In June 2012, as part of the Substance Groupings Initiative,a Notice was issued in the Canada Gazette, (Part I: Vol. 146, No. 26 – June 30, 2012)under section 71 of the CEPA and applied to 13 substances which are part of the Substituted Diphenylamine Substance Grouping. This Noticecollected information from the 2011 calendar year and is the basis for this summary.

Organizations that did not meet the reporting requirements of the Notice but possessed information required in the Notice, or any other information to assist with the assessment of the Substituted Diphenylamine substances, were encouraged to provide it on a voluntary basis. Moreover, those who had a commercial interest for the substances (whether past, future or potential), or simply wanted to be kept informed on the outcome of the assessment, were encouraged to identify themselves as stakeholders by completing a Declaration of Stakeholder Interest.

Additional information on the Substance Groupings Initiative can be found on the Chemical Substances Website.For more information on the Substituted Diphenylamine Substance Grouping, including the associated section 71 Notice and risk assessments, please consult the corresponding substance grouping webpage.

Summary of Information Collected

The following tables summarize both mandatory and voluntary responses received on the 13 substances listed in the section 71 Notice.

Table 1: Submissions received for Substituted Diphenylamine substances

Type of Submission / Number of Submissions Received
Section 71 Notice / 31
Declaration of Stakeholder Interest / 21
Other voluntary submissions of information / 39

Table 2: Substituted Diphenylamine substances reported

Data Received / Number of Substances (13)
Reported
Via responses to the Notice / 10
Via voluntary responses such as the Declaration of Stakeholder Interest* / 7
Substances reported in responses to the Notice
Manufactured / 3
Imported / 9
Used / 6
Exported / 4
Intended for use in commercial activities / 10
Intended for use in consumer activities / 8
Intended for use by or for children / 2

*Number of explicitly declared substances. However, a total of 8 organizations indicated an interest in all 13 substances by means of a “blanket” Declaration of Stakeholder Interest

Table 3: Substituted Diphenylamine substances most frequently reportedas manufactured, imported, used and exported in 2011, at a concentration equal to or above 0.1 percent by weight (w/w%)

Refer to the Compilation of non-confidential data received (Excel) for substances reported as imported or used in 2011 at a concentration less than 0.1 percent by weight (w/w%).

# times reported / CAS RN[3] / Substance Name
31 / 68411-46-1 / Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene
19 / 36878-20-3 / Benzenamine, ar-nonyl-N-(nonylphenyl)-
17 / 10081-67-1 / Benzenamine, 4-( 1-methyl-1-phenylethyl)-N-[4-( 1-methyl-1-phenylethyl) phenyl)-
5 / 68442-68-2 / Benzenamine, N-phenyl-, styrenated
4 / 68608-77-5 / Benzenamine, 2-ethyl-N-(2-ethylphenyl)-, (tripropenyl) derivs.

Table 4: The top Substituted Diphenylamine substances manufactured, imported, used and exported in 2011, at a concentration equal to or above 0.1 percent by weight (w/w%), based on total quantity reported

To protect CBI, some total quantities are provided in the form of ranges. Refer to the Compilation of non-confidential data received (Excel) for individual quantities reported.

Activity / CAS RN / Substance Name / Total Quantity (kg)
Manufactured / 36878-20-3 / Benzenamine, ar-nonyl-N-(nonylphenyl)- / 10,000,000-100,000,000
68411-46-1 / Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene / 1,000,000-10,000,000
10081-67-1 / Benzenamine, 4-( 1-methyl-1-phenylethyl)-N-[4-( 1-methyl-1-phenylethyl) phenyl)- / 100,000-1,000,000
Imported / 36878-20-3 / Benzenamine, ar-nonyl-N-(nonylphenyl)- / 3,070,953
68411-46-1 / Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene / 398,004
68608-77-5 / Benzenamine, 2-ethyl-N-(2-ethylphenyl)-, (tripropenyl) derivs. / 10,000-100,000
68608-79-7 / Benzenamine, N-phenyl-, (tripropenyl) derivs. / 35,000
10081-67-1 / Benzenamine, 4-( 1-methyl-1-phenylethyl)-N-[4-( 1-methyl-1-phenylethyl) phenyl)- / 25,192
Used / 36878-20-3 / Benzenamine, ar-nonyl-N-(nonylphenyl)- / 1,681,418
68411-46-1 / Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene / 212,318
68608-79-7 / Benzenamine, N-phenyl-, (tripropenyl) derivs. / 10,000-100,000
101-67-7 / Benzenamine, 4-octyl-N-(4-Octylphenyl)- / 1,000-10,000
10081-67-1 / Benzenamine, 4-( 1-methyl-1-phenylethyl)-N-[4-( 1-methyl-1-phenylethyl) phenyl)- / 7,412
Exported / 36878-20-3 / Benzenamine, ar-nonyl-N-(nonylphenyl)- / 10,000,000-100,000,000
68411-46-1 / Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene / 1,000,000-10,000,000
10081-67-1 / Benzenamine, 4-( 1-methyl-1-phenylethyl)-N-[4-( 1-methyl-1-phenylethyl) phenyl)- / 100,000-1,000,000

Table 5: Industry sectors, identified by NAICS[4] codes, most frequently reported, and non-confidential Substituted Diphenylamine substances reported for each sector

NAICS codes with the same first four digits are grouped together to determine the overall ranking. Refer to the Compilation of non-confidential data received (Excel) for all non-confidential NAICS codes reported and associated substances.

# times reported / Industry Sector (NAICS Codes and Descriptions) / CAS RN
16 / Petroleum Refineries and coal product manufacturing
324110:Petroleum refineries
324190:Other petroleum and coal product manufacturing
324191:Other petroleum and coal product manufacturing / 36878-20-3
68411-46-1
68442-68-2
68608-77-5
68608-79-7
14 / 418410: Chemical (except agricultural) and allied product merchant wholesalers / 68411-46-1
68608-77-5
184378-08-3
*
9 / 325998: Miscellaneous Chemical Product and Preparation Manufacturing
325999: Miscellaneous Chemical Product and Preparation Manufacturing / 36878-20-3
68411-46-1
*
8 / Rubber Products Manufacturing
3262: Rubber product manufacturing
32629: Other rubber product manufacturing
326290: Other rubber product manufacturing / 68411-46-1
10081-67-1
8 / 412110: Petroleum and petroleum products merchant wholesalers / 36878-20-3
68411-46-1
68608-79-7

*Additional substances were reported under these sectors but the information was claimed as CBI by the submitters.

Table 6: Substance Function Codes[5] most frequently reported for Substituted Diphenylamine substances, and non-confidential substances reported for each code

Refer to the Compilation of non-confidential data received (Excel) for all non-confidential Substance Function Codes reported, as well as the quantity of substance manufactured, imported or used for each applicable code.

# times reported / Substance Function Code5 / Title of Code / CAS RN
29 / U017 / Lubricants and lubricant additives / 10081-67-1
36878-20-3
68411-46-1
68442-68-2
68608-77-5
68608-79-7
184378-08-3
12 / U999 / Other: Anti-oxidant / 10081-67-1
68411-46-1
*
5 / U015 / Intermediates / 68411-46-1
*

*Additional substances were reported in association with these Substance Function Codes, but the information was claimed as CBI by the submitters.

Table 7: Consumer and Commercial Codes most frequently reported for Substituted Diphenylamine substances, and non-confidential substances reported for each code

Refer to the Compilation of non-confidential data received (Excel) for all non-confidential Consumer and Commercial Codes reported, as well as the quantity of substance manufactured, imported or used for each applicable code.

# times reported / Consumer and Commercial Code / Title of Code / CAS RN
47 / C402 / Lubricants and Greases / 10081-67-1
15721-78-5
36878-20-3
68411-46-1
68442-68-2
68608-77-5
68608-79-7
184378-08-3
*
18 / C102 / Foam Seating and Bedding / 68411-46-1
*
17 / C303 / Plastic and Rubber materials not otherwise covered in this table / 10081-67-1
68411-46-1
68442-68-2
7 / C999 / Other : various descriptions / 68411-46-1
*
7 / C201 / Adhesives and Sealants / 10081-67-1
*

*Additional substances were reported in association with these Consumer and Commercial Codes, but the information was claimed as CBI by the submitters.

Tables 8 and9 refer to substances, or mixtures, products or manufactured items containing the substances, most frequently reported as intended for use in commercial activities and for use in consumer activities.

Refer to the Compilation of non-confidential data received (Excel) for all non-confidential intended use information reported.

Table 8: Substituted Diphenylamine substances most frequently reported as intended for use in commercial activities

#times reported / CAS RN / Substance Name
25 / 68411-46-1 / Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene
13 / 36878-20-3 / Benzenamine, ar-nonyl-N-(nonylphenyl)-
11 / 10081-67-1 / Benzenamine, 4-( 1-methyl-1-phenylethyl)-N-[4-( 1-methyl-1-phenylethyl) phenyl)-
4 / 68442-68-2 / Benzenamine, N-phenyl-, styrenated
3 / 68608-79-7 / Benzenamine, N-phenyl-, (tripropenyl) derivs.

Table 9: Substituted Diphenylamine substances most frequently reported as intended for use in consumer activities

#times reported / CAS RN / Substance Name
10 / 68411-46-1 / Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene
8 / 36878-20-3 / Benzenamine, ar-nonyl-N-(nonylphenyl)-
5 / 10081-67-1 / Benzenamine, 4-( 1-methyl-1-phenylethyl)-N-[4-( 1-methyl-1-phenylethyl) phenyl)-
3 / 68608-79-7 / Benzenamine, N-phenyl-, (tripropenyl) derivs.

Table 10: Unpublished studies received on ecological endpoints (any calendar year) for Substituted Diphenylamine substances. Shaded squares indicate that studies for the endpoint were not requested under the Notice for the CAS RN in question. “Y” indicates that at least one study was received for the applicable endpoint

CAS RN / Melting point / Boiling point / Vapour pressure / Water solubility / Octanol-water partition coefficient / Organic carbon-water partition coefficient / Acid disassociation constant / Biodegradation / Bioaccumulation factor, bioconcentration factor and biomagnification factor / Ecotoxicity (experimental acute and chronic studies for pelagic, benthic and terrestrial organisms) / Environmental monitoring and presence / Chemical transformation / Leaching potential
101-67-7
4175-37-5
10081-67-1
15721-78-5
24925-59-5
26603-23-6
27177-41-9
36878-20-3 / Y / Y / Y / Y
68411-46-1 / Y / Y / Y
68442-68-2
68608-77-5
68608-79-7
184378-08-3

Table 11: Unpublished studies received on human health endpoints (any calendar year) for Substituted Diphenylamine substances. Shaded squares indicate that studies for the endpoint were not requested under the Notice for the CAS RN in question. “Y” indicates that at least one study was received for the applicable endpoint

CAS RN / Acute toxicity (oral, dermal and inhalation) / Short-term toxicity (oral. dermal and inhalation) / Sub-chronic toxicity (oral. dermal and inhalation) / Carcinogenicity / Genotoxicity (in vitro) / Genotoxicity (in vivo) / Development and reproductivity / Irritation and sensitization / Absorption, distribution, metabolism and excretion / Biomonitoring
101-67-7
4175-37-5
10081-67-1 / Y / Y / Y / Y
15721-78-5 / Y
24925-59-5
26603-23-6
27177-41-9
36878-20-3 / Y / Y / Y / Y / Y / Y / Y / Y / Y
68411-46-1 / Y / Y / Y / Y / Y / Y / Y / Y
68442-68-2 / Y
68608-77-5 / Y
68608-79-7
184378-08-3 / Y / Y / Y

Contacts

For additional questions about information gathered on the Substituted Diphenylamine Substance Grouping, please contact us via the Substances Management Information Line.

1

[1]“Confidential Business Information” or “CBI” is the information for which a request for confidentiality has been made under section 313 of the Canadian Environmental Protection Act, 1999 (CEPA).

[2]Sensitive information is information for which a request for confidentiality has not necessarily been made under section 313 of CEPA, but that is provided to the Government in confidence.

[3] Chemical Abstract Service Registry Number

[4]North American Industry Classification System codes

[5]Substance Function code is referred to as “Industrial Function Code” in the Notice.