Supplementary Table 6A

name p.hyper n.signif.gasch n.gasch.tested enrich benj.p

Cluster_DAL82 0.0216975248666298 3 14 4.79859484777518 0.923474953120648

Node 73 0.0236788449518115 15 199 1.68794793640333 0.923474953120648

Cluster_MTH1 0.0700832393158373 2 10 4.47868852459016 1

Node 36 0.0778696572331514 5 52 2.15321563682219 1

Node 7 0.129478474299861 6 78 1.72257250945776 1

Cluster_Sterols 0.141965728416127 2 15 2.98579234972678 1

Cluster_ManualG1genes 0.206860913214004 2 19 2.3572044866264 1

Cluster_NuclearProteinTargetting 0.32496071278227 2 26 1.72257250945776 1

Cluster_SFL1 0.367695633868481 1 10 2.23934426229508 1

Cluster_adata-TUB 0.367695633868481 1 10 2.23934426229508 1

Cluster_CBF1 0.3961400043213 1 11 2.03576751117735 1

Cluster_PHD1 0.3961400043213 1 11 2.03576751117735 1

Cluster_PUT3 0.3961400043213 1 11 2.03576751117735 1

Cluster_STE12 0.3961400043213 1 11 2.03576751117735 1

Cluster_STP1 0.3961400043213 1 11 2.03576751117735 1

Cluster_SIG1 0.423324845455175 1 12 1.86612021857923 1

Cluster_REB1 0.449305040748554 1 13 1.72257250945776 1

Cluster_RGT1 0.449305040748554 1 13 1.72257250945776 1

Cluster_SKN7 0.449305040748554 1 13 1.72257250945776 1

Cluster_Purine 0.449305040748554 1 13 1.72257250945776 1

Cluster_mRNAprocessing 0.461805161727926 3 56 1.19964871194379 1

Cluster_RTG1 0.520531886473045 1 16 1.39959016393443 1

Cluster_Phospholipid 0.520531886473045 1 16 1.39959016393443 1

Cluster_ManualYap1Targets 0.542196741973151 1 17 1.31726133076181 1

Cluster_adata-CalciumSpecific 0.542196741973151 1 17 1.31726133076181 1

Cluster_primig-LateSpo 0.542552389403736 3 63 1.06635441061671 1

Cluster_PUF4 0.54403260501753 4 86 1.04155547083492 1

Cluster_GeneralTFs 0.562898001231593 1 18 1.24408014571949 1

Cluster_primig-EarlySpo 0.562898001231593 1 18 1.24408014571949 1

Cluster_Proteasome 0.582677839454793 1 19 1.1786022433132 1

Cluster_ManualHAP1targets 0.601576615841769 1 20 1.11967213114754 1

Cluster_GCN4 0.61963295048787 1 21 1.06635441061671 1

Cluster_ABF1 0.653364518560312 1 23 0.973627940128297 1

Cluster_Vacuole 0.725350472649882 1 28 0.79976580796253 1

Node 72 0.767674437845449 3 88 0.763412816691505 1

Cluster_RNAPol 0.77216271547497 1 32 0.699795081967213 1

Cluster_PUF5 0.94996401668776 1 64 0.349897540983607 1

Cluster_PUF3 0.965950720870735 1 72 0.311020036429873 1

Node 31 1 0 12 0 1

Node 32 1 0 13 0 1

Node 39 1 0 10 0 1

Node 45 1 0 27 0 1

Node 67 1 0 21 0 1

Node 68 1 0 14 0 1

Cluster_ADR1 1 0 14 0 1

Cluster_CIN5 1 0 17 0 1

Cluster_DOT6 1 0 16 0 1

Cluster_FKH2 1 0 15 0 1

Cluster_GCR2 1 0 11 0 1

Cluster_GTS1 1 0 10 0 1

Cluster_HAP2 1 0 11 0 1

Cluster_HAP3 1 0 13 0 1

Cluster_HAP5 1 0 12 0 1

Cluster_INO2 1 0 10 0 1

Cluster_MAC1 1 0 10 0 1

Cluster_MAL33 1 0 13 0 1

Cluster_MBP1 1 0 13 0 1

Cluster_MCM1 1 0 11 0 1

Cluster_MET4 1 0 10 0 1

Cluster_MIG1 1 0 14 0 1

Cluster_MSS11 1 0 11 0 1

Cluster_NDD1 1 0 12 0 1

Cluster_SIP4 1 0 13 0 1

Cluster_SRD1 1 0 12 0 1

Cluster_SWI4 1 0 17 0 1

Cluster_SWI5 1 0 13 0 1

Cluster_USV1 1 0 12 0 1

Cluster_Endocytosis 1 0 11 0 1

Cluster_FattyAcid 1 0 14 0 1

Cluster_Mitochondria 1 0 19 0 1

Cluster_tRNAsynth 1 0 13 0 1

Cluster_tRNAprocessing 1 0 14 0 1

Cluster_ManualZAP1targets-2 1 0 27 0 1

Cluster_adata-Secretion 1 0 16 0 1

Cluster_adata-RET3 1 0 15 0 1

Cluster_adata-ARG3 1 0 12 0 1

Node 2_fuzzy0.06 1 0 20 0 1

Cluster_ManualMethionine 1 0 12 0 1

Supplementary Table 6B

name p.hyper n.signif.GO n.GO.tested enrich benj.p

GO:0007124 9.06905331855199e-05 7 25 6.01846153846154 0.00344624026104976

GO:0006950 0.000451533480979835 20 197 2.18218329893457 0.00857913613861687

GO:0006259 0.00585699739323772 13 130 2.14945054945055 0.0741886336476778

GO:0007126 0.0310972468387226 6 52 2.48013524936602 0.295423844967865

GO:0005975 0.0457320493368633 8 87 1.97650625236832 0.347563574960161

GO:0006350 0.0678558596863024 17 252 1.45002616431188 0.372511238207156

GO:0006464 0.0686204912486866 16 234 1.46970977740209 0.372511238207156

GO:0007049 0.100152428926082 12 173 1.49094835800038 0.47572403739889

GO:0007165 0.137461905713367 7 93 1.61786600496278 0.532374499291654

GO:0042221 0.140098552445172 10 147 1.46221125812963 0.532374499291654

GO:0030163 0.212620983497459 7 105 1.43296703296703 0.734508852082131

GO:0006996 0.233784484305445 24 445 1.15925422891715 0.740317533633909

GO:0007114 0.377315836910534 2 28 1.53532182103611 0.905543270374268

GO:0016192 0.38273123442386 8 148 1.16186516186516 0.905543270374268

GO:0042254 0.390104345416776 8 149 1.15406740910097 0.905543270374268

GO:0009653 0.401104902950008 3 49 1.31599013231666 0.905543270374268

GO:0006629 0.405457029532945 6 110 1.17242757242757 0.905543270374268

GO:0016070 0.430041073763522 22 449 1.05318289728089 0.905543270374268

GO:0008150 0.482153202123391 6 119 1.0837565795549 0.905543270374268

GO:0030435 0.488605102234988 3 56 1.15149136577708 0.905543270374268

GO:0006810 0.514315960989154 18 381 1.01548844855931 0.905543270374268

GO:0019725 0.524261893374576 3 59 1.09294095734774 0.905543270374268

GO:0006091 0.566181305363603 4 85 1.01150614091791 0.917350284833307

GO:0007047 0.585099511350107 4 87 0.98825312618416 0.917350284833307

GO:0000746 0.603519924232439 2 43 0.999744441604907 0.917350284833307

GO:0016044 0.672312818479699 4 97 0.886371360598165 0.946544400101826

GO:0006412 0.683090350849319 5 122 0.880922356332192 0.946544400101826

GO:0051186 0.71481642817962 3 78 0.826711749788673 0.946544400101826

GO:0006725 0.751373837497818 1 29 0.74118984463812 0.946544400101826

GO:0006519 0.775484207924263 3 86 0.74980833120368 0.946544400101826

GO:0007010 0.831282194771634 1 37 0.580932580932581 0.946544400101826

GO:0000910 0.831282194771634 1 37 0.580932580932581 0.946544400101826

GO:0006457 0.839282882773604 1 38 0.565644881434355 0.946544400101826

GO:0045333 0.846908147459528 1 39 0.551141166525782 0.946544400101826

GO:0006997 1 0 26 0 1

GO:0006766 1 0 38 0 1

GO:0046483 1 0 40 0 1

GO:0032196 1 0 13 0 1