MONITORING CHECKLIST EXAMPLES

  1. PROCEDURES RECORD/ TREATMENT SHEETS

Ethics No ...... Species ...... Strain ...... …….

Group/ Individual Identification ...... Cross Reference# ......

Date / Checked / Details (procedure or treatment) / Initials
NAD / Checklist

*Please complete NAD (No abnormalities detected), “Checklist” when records transferred to monitoring checklist, or details of procedures or problems in the “Details” column.

#Use this section to cross reference an animal removed from a group to an individual record sheet.

  1. EXAMPLE OF USE OF THIS RECORD WITH MONITORING CHECKLIST

PROCEDURES RECORD/ TREATMENT SHEETS- completed example

Ethics No: 999 1206Species: SheepBreed: Merino

Group/ Individual Identification: Sheep #5Cross Reference#: Checklist #5

Date / Checked / Details (procedure or treatment) / Initials
NAD / Checklist
8/3/11 /  / Delivered from Central Animal House to MSB Animal Facility / AB
9/3/11 /  / AB
10/3/11 /  / AB
11/3/11 /  / AB
12/3/11 /  / AB
13/3/11 /  / AB
14/3/11 /  / AB
15/3/11 /  / CD
16/3/11 /  / Surgery. Transferred to checklist / AB
17-22/3/11 / See monitoring checklist
23/3/11 /  / Transferred from monitoringchecklist / AB
24/3/11 /  / AB
25/3/11 /  / Final non-recovery study.
Animal euthanased. / CD

*Please complete NAD (No abnormalities detected), “Checklist” when records transferred to monitoring checklist, or details of procedures or problems in the “Details” column.

#Use this section to cross reference an animal removed from a group to an individual record sheet.

  1. EXAMPLE OF MONITORING CHECKLIST FOR SHEEP # 5: First 2 days

ARTERIAL STENOSIS - SHEEP

SHEEP ID: #5
DATE OF OPERATION: 15/3/11 / PRE-OPERATION WEIGHT: 50 kg
Date / 16/3 / 16/3 / 17/3 / 17/3 / 17/3
Day / Mon / Mon / Tues / Tues / Tues
Time / 3pm / 6pm / 8am / 9am / 12pm
FROM A DISTANCE
Isolated / + / - / + / + / +
Teeth grinding / - / - / - / - / +
Breathing frequency / min / 14 / 14 / 16 / 16 / 25
ON HANDLING
Weight (kg) / 48
Weight change (+ / - %) / - 4%
Temperature 0 C / 39.0 / 39.0 / 39.5 / 39.5 / 39.5
Wound abnormal / - / - / -/+ / -/+ / -/+
Leg feels cool / - / - / - / - / -
Reduced femoral pulse / - / - / - / - / -
Leg: paresis / - / - / - / - / -
Lameness / - / - / -/+ / - / -
Reluctant to move / + / - / - / -
Other signs noted / Alert / Alert / Alert / Alert / Alert
NAD
Notes / Surgical site - To check with vet
Signature / AB / AB / AB / AB / AB

Criteria for action: Increase monitoring frequency andConsult CI or veterinarian if:

Body weight loss

Body weight gain is not normal

Raised body temperature (normal body temp: 39-40 0 C)

Increased breathing frequency (normal rate: 12-20 / min)

Any one of the signs is present

Humane endpoints:

> 10% bodyweight loss

lameness persisting for > 24 hours

inappetence/reduced appetite for 3 days

  1. EXAMPLE MONITORING CHECKLIST FOR RODENT TUMOUR PROTOCOLS

Project Title:

ACEC Approval Number:

Individual ID:Tumour location:

NOTE: place an ‘x’ against any clinical signs that are present. Use the intervention instructions at the base of the sheet to ensure that the correct action is taken. NAD- No abnormalities detected.

Date
Time
Action
NAD
Signature
Clinical and behavioural signs observed
Category 1 signs
Ruffled fur
Decreased activity
Shallow or increased respiratory rate
Isolated from cagemates
Category 2 signs
Thin
Ungroomed
Coughing/ sneezing
Aggression
Abdominal swelling
Hunched posture
Category 3 signs
Emaciated
Pale or cyanotic ears/nose/feet
Yellow ears/nose/feet
Gasping respiration
Moribund
Tumour >20% body weight
Tumour affecting normal activity
COMMENTS

NAD- no action

Category 1- monitor again in 4 hours, if not improved seek advice from CI or veterinarian

Category 2- contact Chief investigator and veterinarian for advice

Category 3- euthanase immediately. Ensure post mortem performed. Submit adverse event report to ACEC

Any combination of signs-

More than two signs in any one category- treat as next highest category

Signs from more than one category- treat as for highest category

Guidelines to Use of Monitoring Checklist

  1. Use the general Animal Services monitoring checklist (provided in the procedures/treatment record folder – red folder) to record monitoring information until animals develop tumours.
  2. Use this specific checklist once a tumour is detected in an animal.
  3. Ensure all monitoring checklists are held in the red folders in the room in which the animals are held.
  4. Monitor animals in accordance with and as frequently as required by the Animal Care and Ethics approval.
  5. One specific monitoring sheet per animal is used.
  6. Where an abnormal clinical sign in an animal has been detected, use the Animal Services Unit provided “sick’ card to identify the cage.
  7. Where an abnormal clinical sign in an animal has been detected make a notation in the ASU provided checklist in the red folder of the action taken. Make sure the animal identification is included in this notation.

  1. EXAMPLE MONITORING CHECKLIST- Lung Inflammation Protocols

Project Title:

ACEC Approval Number:

Group ID:Individual ID:

NOTE: place an ‘x’ against any clinical signs that are present. Use the intervention instructions at the base of the sheet to ensure that the correct action is taken. NAD- No abnormalities detected.

Date
Time
Procedure
Initials/ signature
NAD
Category 1 signs
Ruffled fur
Reddening at injection site
Decreased activity
Shallow or increased respiratory rate
Isolated from cagemates
Category 2 signs
Thin
Ungroomed
Reddening and swelling at injection site
Coughing/ sneezing
Aggression
Abdominal swelling
Hunched posture
Category 3 signs
Emaciated
Pale or cyanotic ears/nose/feet
Gasping respiration
Moribund
COMMENTS

NAD- no action

Category 1- monitor again in 4 hours, if not improved seek advice from CI or veterinarian

Category 2- contact Chief investigator and veterinarian for advice

Category 3- euthanase immediately. Ensure post mortem performed. Submit adverse event report to ACEC

Any combination of signs-

More than two signs in any one category- treat as next highest category

Signs from more than one category- treat as for highest category

Guidelines to Use of Monitoring Checklist- Lung Inflammation Protocols

  1. Use the general Animal Services monitoring checklist (provided in the procedures/treatment record folder – red folder) to record monitoring information until animals enter the active research protocol.
  2. Once a procedure has been performed on an animal use this specific checklist.
  3. Ensure all monitoring checklists are held in the red folders in the room in which the animals are held.
  4. Monitor animals in accordance with and as frequently as required by the Animal Care and Ethics approval.
  5. One monitoring sheet per group of animals can be used. A group may be a cage, and experimental group, or all of the animals in that research protocol.
  6. If an abnormality is detected with one or more animals in the group then that animal (or animals) must be transferred to an individual monitoring checklist i.e. there must be one checklist per animal exhibiting a problem.
  7. Record the group ID on the group checklist (e.g. cage number). Leave the individual ID section blank.
  8. If an animal is transferred to an individual monitoring checklist record the group ID (e.g. cage in which they are housed) and individual ID on the individual checklist. This means that any checklist with an “x” against anything other than NAD should have a corresponding individual animal checklist. If the animal returns to normal it can be returned to the group checklist (make a notation to this effect on the individual checklist)
  9. Where an abnormal clinical sign in an animal has been detected, use the Animal Services Unit provided “sick’ card to identify the cage.
  10. Where an abnormal clinical sign in an animal has been detected make a notation in the ASU provided checklist in the red folder of the action taken. Make sure the animal identification is included in this notation.