CURRICULUM VITAEFebruary, 2009

1. EDUCATION

9/1994-6/1998Northwestern UniversityMedicalSchool

Chicago, Illinois

Doctor of Medicine

9/1991-6/1994Northwestern University – College of Arts and Sciences

Honors Program in Medical Education

Evanston, Illinois

Bachelor of Arts in English Literature

8/1987-6/1991AndoverHigh School

Bloomfield Hills, Michigan

Graduated with Honors

2. POST-GRADUATE TRAINING

7/2002-6/2005ChildrensHospitalLos Angeles

Los Angeles, California

Pediatric Pulmonology Fellowship

7/1998-6/2001Rush Children’s Hospital

Chicago, Illinois

General Pediatrics Residency

3FACULTY POSITIONS HELD

7/2007-currentAssistant Professor

Associate Director, Pediatric SleepDisordersCenter

Department of Pediatrics, Pulmonary Division

Children’s Hospital and RegionalMedicalCenter

University of WashingtonSchool of Medicine

Seattle, Washington

7/2005-6/2007Acting Assistant Professor

Department of Pediatrics, Pulmonary Division

Associate Director, Pediatric SleepDisordersCenter

Children’s Hospital and RegionalMedicalCenter

University of WashingtonSchool of Medicine

Seattle, Washington

4. HOSPITAL POSITIONS HELD

8/2001-7/2002Pediatrician and Hospitalist

KaiserPermanenteWestLos AngelesMedicalCenter

10/2001-7/2002Pediatrician (per diem)

KaiserPermanenteLos AngelesMedicalCenter

5. HONORS

2005Best Poster Award, Saban Research Institute

ChildrensHospitalLos Angeles

2005Ching-I Wong Research Award

Outstanding Research in Pediatric Pulmonology

ChildrensHospitalLos Angeles

2003Fellow of the Year, recognition for teaching

ChildrensHospitalLos Angeles

2001Outstanding Teaching Resident Award

Rush Children’s Hospital

1994Deru Honor Society for Student Leaders

Northwestern University

6. BOARD CERTIFICATION

6/1996USMLE Step I

3/1998USMLE Step II

7/2000USMLE Step III

10/2001Diplomate, American Board of Pediatrics

10/2006 Diplomate, Sub-board of Pediatric Pulmonology

11/2007Diplomate, Sub-board of Sleep Medicine

7. CURRENT LICENSES

3/31/2005Licensure, State of Washington Health Professions Quality Assurance Division

8. PROFESSIONAL ORGANIZATIONS

2005-presentSleep Research Society, Member

2005-presentAmerican Academy of Sleep Medicine, Member

2003-presentAmerican Thoracic Society, Member

2002-presentAmericanAcademy of Pediatrics, Fellow

1998-2001American Academy of Pediatrics, Resident Member

9. TEACHING RESPONSIBILITIES

7/2002- 6/2005University of Southern California Medical School

Pediatric Clerkship Pulmonology Lecture

8/2005- currentUniversity of Washington School of Medicine

  • Pediatric Pulmonary Fellowship: supervision of in-patient rounds, out-patient clinical care, and Sleep Medicine rotation
  • Sleep Medicine Fellowship: participation in Pediatric Sleep Medicine elective
  • Pediatrics Residency Program
  • formal didactic lectures on Sleep Medicine in noon conference schedule
  • Pulmonary service: supervision of in-patient patients with the ward team
  • Pulmonary Elective rotation: supervision of Pulmonary and Sleep medicine consultations on an in-patient and clinic setting
  • Pediatric Core Clerkship (medical students)
  • formal didactic lectures on Sleep Medicine in clerkship lecture series
  • Pulmonary service: supervision of in-patient patients with the ward team
  • Pulmonary Elective rotation: supervision of Pulmonary and Sleep medicine consultations on an in-patient and clinic setting

10. EDITORIAL RESPONSIBILITIES

none

11. SPECIAL NATIONAL RESPONSIBILITIES

none

12. SPECIAL LOCAL RESPONSIBILITIES

none

13. RESEARCH FUNDING

X Active Pending

Role: Principal Investigator

Source: University of Washington, Center for Clinical and Translational Research Title: Mentored Scholar Program

Dates: 1/1/2009 – 12/31/2010

Costs: $20,000

Effort: 60%

Dr. Chen’s research time and career development is funded at 60% FTE by this award. In addition, it provides additional funding for pilot research. The major goals of the planned research project are to characterize sleep fragmentation, autonomic regulation, stress reactivity, and daytime temperaments of infants with prenatal alcohol exposure.

14. BIBLIOGRAPHY

a) MANUSCRIPTS

  1. J. Silvestri, M.L. Chen, D. Weese-Mayer, J. McQuitty, H. Carveth, D. Nielson, D. Borowitz, and F. Cerny. Idiopathic Congenital Central Hypoventilation Syndrome: The Next Generation. American Journal of Medical Genetics. 112: 46-50, 2002.
  2. M.L. Chen, M.B. Witmans, M.A. Tablizo, R.F. Jubran, S.B. Turkel, C. J. Tavaré, and T.G. Keens. Disordered respiratory control in control with partial cerebellar resections. Pediatric Pulmonology. 40: 88-91, 2005.
  3. M.L. Chen, M.A. Tablizo, S. Kun, and T. G. Keens. Diaphragm pacers as a treatment of congenital central hypoventilation syndrome. Expert Review of Medical Devices. 2(5): 577-585, 2005.
  4. M.L. Chen, S.B. Turkel, J.R. Jacobson, and T.G. Keens. Alcohol use in congenital central hypoventilation syndrome. Pediatric Pulmonology, 41: 283-285, 2006.
  5. M.A. Tablizo, P. Jacinto, D. Parsley, M.L. Chen, R. Ramanathan, T.G. Keens. Supine sleeping position does not cause clinical aspiration in neonates in hospital newborn nurseries. Archives of Pediatric and Adolescent Medicine,161(5):507-10, 2007.
  6. A.M. Striegl, M.L. Chen. Management of obstructive sleep apnea in patients with congenital heart disease and Fontan procedures. Sleep Medicine, 8:537-8, 2007.
  7. T. Hsieh, M. Chen, A. McAfee, Y. Kifle. Sleep-related breathing disorder in children with vagal nerve stimulators. Pediatric Neurology, 38(2): 99-103, 2008.

b) BOOK CHAPTERS

  1. M.B. Witmans, M.L. Chen, S.L. Davidson Ward, and T.G. Keens. Congenital syndromes affecting respiratory control during sleep. In T. Lee-Chiong, ed. Sleep: a Comprehensive Handbook. Wiley and Sons, Hoboken, New Jersey. Chapter 66, pp. 517-527, 2006.

c) PUBLISHED BOOKS

none

d)OTHER PUBLICATIONS

  1. M.L. Chen, and T.G. Keens. Congenital Central Hypoventilation Syndrome. ADVANCEforSleep.com (online journal). July, 2003.
  2. M.L. Chen, and T.G. Keens. Congenital Central Hypoventilation Syndrome: not just another rare disorder. Paediatric Respiratory Reviews, 5(3): 182-189, 2004.

e) SUBMITTED MANUSCRIPTS

1. J. Chaicharn, Z. Lin, M.L. Chen, T.G. Keens, S.L. Davidson Ward, M.C.K. Khoo. Model-based assessment of cardiovascular autonomic control in children with obstructive sleep apnea. Submitted to Sleep, revised and resubmitted 3/15/2009.

f) ABSTRACTS

1.J.A. Fraire, M. Chen, N. Kapoor, A. Shah, and T.G. Keens. Predicting pulmonary complications following bone marrow transplantation in infants and young children. American Journal of Respiratory and Critical Care Medicine. 167(7): A516, 2003.

2.M.L. Chen, M.B. Witmans, M.A. Tablizo, R.F. Jubran, S.B. Turkel, C.J. Tavaré, and T.G. Keens. Disordered respiratory control in children with partial cerebellar resections. American Journal of Respiratory and Critical Care Medicine. 169(7): A733, 2004.

3.M.B. Witmans, M.L. Chen, S.S. Kun, R.F. Jubran, T.G. Keens, and S.L. Davidson Ward. Long-term mechanical ventilation in patients with brainstem lesions. American Journal of Respiratory and Critical Care Medicine. 169(7): A684, 2004.

4.M.A. Tablizo, D. Parsley, P. Jacinto, R. Ramanathan, M.L. Chen, and T.G. Keens. Supine sleeping position does not cause clinical aspiration in neonates in hospital newborn nurseries. American Journal of Respiratory and Critical Care Medicine. 169(7): A734, 2004.

5.Z. Lin, M.L. Chen, T.G. Keens, S.L.D. Ward, and M.C.K. Khoo. Noninvasive assessment of cardiovascular autonomic control in congenital central hypoventilation syndrome. Proc 26th Annual IEEE EMBS Conference, p.3870-3873, 2004.

6.M.L. Chen, Z. Lin, M.C.K. Khoo, S.L. Davidson Ward, and T.G. Keens. Cardiorespiratory Uncoupling in Congenital Central Hypoventilation Syndrome. Proceedings of the American Thoracic Society, 2: A461, 2005.

7.Z. Lin, M.L. Chen, T.G. Keens, S.L. Davidson Ward, and M.C.K. Khoo. Model-based assessment of Autonomic System Dysfunction in Congenital Central Hypoventilation Syndrome. Proceedings of the American Thoracic Society, 2: A460, 2005.

8.Z. Lin, M.L. Chen, T.G. Keens, S.L. Davidson Ward, and M.C.K. Khoo. Model-based assessment of cardiovascular autonomic control in pediatric Obstructive Sleep Apnea Syndrome. Proceedings of the American Thoracic Society, 2: A878, 2005.

  1. M.L. Chen, Z. Lin, M.C.K. Khoo, T.G. Keens, and S. L. Davidson Ward. Autonomic Dysfunction in Obstructive Sleep Apnea Syndrome. Proceedings of the American Thoracic Society, 2: A895, 2005.

10.M.A. Tablizo, T. Hoppenbrouwers, M.L. Chen, X. Liu, F. Dorey, S.L. Davidson Ward, R. Ramanathan, and T.G. Keens. Cardiorespiratory Events During Upper Respiratory Infections in Infants. Proceedings of the American Thoracic Society, 2: A460, 2005.

11.S. B. Turkel, M. L. Chen, J. R. Jacobson, and T.G. Keens. Consequences of Abnormal Anxiety with Congenital Central Hypoventilation Syndrome. Journal of Neuropsychiatry and Clinical Neuroscience, 17:2, 267, 2005.

  1. M.L. Chen, Z. Lin, S.L. Davidson Ward, M.C.K. Khoo, and T.G. Keens. Cardio-respiratory uncoupling in congenital central hypoventilation syndrome. Proceedings of 27th IEEE EMBS Conference, 2005.
  2. Z. Lin, M.L. Chen, T.G. Keens, S.L. Davidson Ward, and M.C.K. Khoo. Noninvasive assessment of cardiovascular autonomic control in pediatric obstructive sleep apnea syndrome. Proceedings of 27th IEEE EMBS Conference, 2005.

14.Z. Lin, M.L. Chen, T.G. Keens, S.L. Davidson Ward, M.C.K. Khoo. Cardiovascular response to cold face stimulation in pediatric obstructive sleep apnea syndrome. Proceedings of the American Thoracic Society, 3: A449, 2006.

  1. J. Chaicharn, Z. Lin, M.L. Chen, T.G. Keens, S.L. Davidson Ward, M.C.K. Khoo. Autonomic control in pediatric obstructive sleep apnea syndrome during cold face stimulation. Proceedings of the American Thoracic Society, 3: A196, 2006.
  2. M.L. Chen, T.G. Keens, S.L.Davidson Ward. Sleep and REM density in children with partial cerebellar resections. Sleep, 29 (abstract supplement): A94, 2006.
  3. M.L. Chen, H.C. Olson, S.J. Astley. Sleepless in Seattle: preliminary data suggesting sleep disorders in those with FASD. Research Society for Alcoholism, Fetal Alcohol Spectrum Disorders Study Group, June 2006.
  4. J. Chaicharn, Z. Lin, M.L. Chen, T.G. Keens, S.L. Davidson Ward, M.C.K. Khoo. Time-varying closed-loop modeling of autonomic control in pediatric obstructive sleep apnea syndrome during cold face stimulation. Proceedings of the 28th IEEE EMBS Conference, 2006.
  5. M.L. Chen, F.B. Lynn, S.C. Casey, A. McAfee, Y. Kifle. Obesity: the new standard in pediatric sleep centers. American Journal of Respiratory and Critical Care Medicine, 177: A705, 2008.
  6. M.L Chen, H. Carmichael Olson. Caregiver report of sleep problems in children with fetal alcohol spectrum disorders. American Journal of Respiratory and Critical Care Medicine, 177: A707, 2008.
  7. A.M.Striegl, M.L. Chen, Y. Kifle, K. Song, G.R. Redding. Sleep disordered breathing in children with thoracic insufficiency syndrome. American Journal of Respiratory and Critical Care Medicine, 177: A706, 2008.
  8. K.H. Archbold, Y.Kifle, A.McAfee, M.L. Chen. Patterns of at-home positive airway pressure (PAP) treatment parameters and adherence patterns in children with obstructive sleep apnea: preliminary results. Sleep, 31 (abstract supplement): A68, 2008.
  9. K.H. Archbold, Y.Kifle, A.McAfee, M.L. Chen. Behavioral and cognitive patterns in children with OSA following three months of positive airway pressure therapy. Sleep, 31 (abstract supplement): A68, 2008.
  10. G. Redding, A. Striegl, M. Chen, Y. Kifle, K. Song. Sleep-related breathing abnormalities in children with thoracic insufficiency syndrome. Accepted, Scoliosis Research Society.
  11. A.M. Landis, E. Bond, Y. Kifle, M.Chen. A retrospective look at relationships among sleep variables and body mass index in children and adolescents. Accepted, Sleep, 2009.

15. PRESENTATIONS

a) Local

  1. M.L. Chen. The Role of the Cerebellum in Respiratory Control. Childrens Hospital Los Angeles, Saban Research Institute, Chalk Talk, May 2005.

b) Regional

  1. M. L. Chen. An Overview of SIDS. California Sudden Infant Death Syndrome Program: Training for Public Health Professionals. Sylmar, California, March 2004.
  2. M. L. Chen. Home Mechanical Ventilation in Children. Childrens Hospital Los Angeles, Videoteleconference with University of Alberta, Stollery Children’s Hospital. Los Angeles, California, September 2004.
  3. M.L. Chen. Autonomic Dysfunction in Obstructive Sleep Apnea Syndrome. ChildrensHospitalLos Angeles, Pediatric Grand Rounds, September 2005.
  4. M.L. Chen. Pediatric Sleep 101. Foster Care Assessment Program Seminar. Seattle, Washington. June 2006.
  5. M.L. Chen. Sleep in Fetal Alcohol Spectrum Disorders. National Organization on Fetal Alcohol Syndrome, Northwest Regional Conference. Lynnwood, Washington. October, 2006.
  6. M.L. Chen. Parental Discretion to Withdraw a Ventilator from a child with Congenital Central Hypoventilation Syndrome. Children’s Hospital and RegionalMedicalCenter, Pediatric Grand Rounds, October 2007.
  7. M.L. Chen. Pediatric Sleep 101. National Association of Pediatric Nurse Practitioners, AnnualWashingtonState Conference. Shoreline, Washington. March 2008.

c) National

d) International