Juxian SONG, Ph.D.

E-mail:

Academic qualifications:

2007.08 – 2011.11 Ph.D. School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong, China.

2003.09 – 2006.07 M.Med.School of Pharmacy, GuiyangMedicalCollege,Guiyang, Guizhou, China.

1999.09 – 2003.07 B.S. School of Pharmacy, GuiyangMedicalCollege, Guiyang, Guizhou, China.

Academic positions:

2012.07 – present Post-doctoral Research Fellow, School of Chinese Medicine, Hong KongBaptistUniversity, Hong Kong SAR.

2012.03 – 2012.06 Research Assistant, School of Chinese Medicine, Hong KongBaptistUniversity, Hong Kong SAR.

Research areas: Autophagy, Chinese herbal medicines, neuropharmacology.

Recent publication Records:

  1. Durairajan S.S.K.,* Huang Y.Y., Yuen P.Y., Chen L.L., Kwok K.Y., Liu L.F., Song J.X. Han Q.B.,Xue L., Chung S. K., Huang J.D., Baum L., Senapati S., Li M.* Huang-Lian-Jie-Du Tang, a Chinese medicine formula exerts neuroprotective effect on a transgenic model of Alzheimer’s disease. PLOS One. 2014; 9(3): e92954.
  2. Chen LL, Song JX, Lu JH, Yuan ZW, Liu LF, Durairajan SS, Li M.* Corynoxine, a Natural Autophagy Enhancer, Promotes the Clearance of Alpha-Synuclein via Akt/mTOR Pathway. J Neuroimmune Pharmacol. 2014 Feb 13. [Epub ahead of print]
  3. Song JX, Lu JH, Liu LF, Chen LL, Durairajan SS, Yue Z, Zhang HQ*, Li M*. HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression: A process modulated by the natural autophagy inducer corynoxine B. Autophagy. 2014; 10(1):144-54.
  4. Song JX, Shaw PC, WongNS, Sze CW, Yao XS, Tang CW, Tong Y, Zhang YB. Chrysotoxine, anovel bibenzyl compound selectively antagonizes MPP, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells. Neurosci Lett. 2012 Jul 11;521(1):76-81.
  5. Song JX, Choi MY, Wong KC, Chung WW, Sze SC, Ng TB, Zhang KY. Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism. Chin Med. 2012 Jan 21;7(1):1.
  6. Song JX, Sze SC, Ng TB, Lee CK, Leung GP, Shaw PC, Tong Y, Zhang YB. Anti-Parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models? J Ethnopharmacol. 2012 Feb 15; 139(3):698-711.
  7. Song JX, Lin X, Wong RN, Sze SC, Tong Y, Shaw PC, Zhang YB. Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells. Phytother Res. 2011 Mar;25(3):435-43.
  8. Song JX, Shaw PC, Sze CW, Tong Y, Yao XS, Ng TB, Zhang YB. Chrysotoxine, a novel bibenzyl compound, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-κB modulation. Neurochem Int. 2010 Nov;57(6):676-89.
  9. Song JX, Li Y, Ge J, Duan Y, Sze SC, Tong Y, Shaw PC, Ng TB, Tsui KC, Zhuo Y, Zhang KY. Protective effect of bilberry (Vaccinium myrtillus L.) extracts on cultured human corneal limbal epithelial cells (HCLEC). Phytother Res. 2010 Apr;24(4):520-4.

Patents：

Li M.,Song J.X. Zeng Y., Liu L.F. “An Autophagy Enhancement and Uses Thereof” U.S. Provisional Patent Application No. P7599US00, 2014