CURRICULUM VITAE

8/1/2013

IDENTICAL INFORMATION

Name: Yasuhiro Maejima

Home address: Hakusan 1-32-8-404, Bunkyo-ku, Tokyo, JAPAN 113-0001

Phone 201-759-9688

Business address: Department of Cardiovascular Medicine,

Tokyo Medical and Dental University

1-5-45, Yushima, 13rd Floor of MD Tower

Bunkyo-ku, Tokyo, JAPAN 113-8519

Phone: +81-3-5803-5231

EDUCATIONAL HISTORY

1989 Graduated from Hamamatsu-Kita High School (Hamamatsu, Japan)

1995 M.D. Shinshu University School of Medicine (Matsumoto, Japan)

2005 Ph.D. (Dr. of Medical Science) Tokyo Medical and Dental University Graduate

School (Tokyo, Japan)

PROFESSIONAL BACKGROUND (EMPLOYMENT HISTORY)

May/ 1996 Passed the Examination of National Board of Physiscian

May/ 1996-Mar/ 1997 Resident in Department of Internal Medicine,

Shinshu University Hospital

Apr/ 1997-Mar/ 1999 Resident in Department of Internal Medicine,

Toranomon Hospital

Apr/ 1999-Mar/ 2001 Senior resident in Department of Cardiovascular Medicine,

Jichi Medical School Omiya (Saitama) Medical Center

Apr/ 2005-Mar/ 2006 Postdoctoral Fellow in Department of Cardiovascular

Medicine, Tokyo Medical and Dental University

Apr/ 2006-Mar/ 2008 Assistant Professor in Department of Cardiovascular

Medicine, Tokyo Medical and Dental University

Apr/ 2008- May/ 2012 Postdoctoral Fellow in Department of Cell Biology and

Molecular Medicine, UMDNJ, New Jersey Medical School

Jun/ 2012 - Jul/ 2013 Assistant Professor in Department of Cell Biology and

Molecular Medicine, UMDNJ, New Jersey Medical School

Oct/ 2012 – Jul/ 2013 Adjunctive Assistant Professor in Department of

Cardiovascular Medicine, Tokyo Medical and Dental University

Aug/ 2013 -Present Assistant Professor in Department of

Cardiovascular Medicine, Tokyo Medical and Dental University;

Adjunctive Assistant Professor in Department of Cell Biology

and Molecular Medicine, New Jersey Medical School, Rutgers,

The State University of New Jersey

PERSONAL INFORMATION

Birth date: January 26, 1971

Birth Place: Hamamatsu, Shizuoka, Japan

Citizenship: Japan

LICENSE AND CERTIFICATION

1996 Japanese Medical License Registration

2005 Diplomat, Japanese Board of Cardiologist

2005 Diplomat, Japanese Board of Physician

MEMBERSHIPS

American Heart Association

Japanese Circulation Society

Japanese Society of Internal Medicine

Japanese Heart Failure Society

International Society of Heart Research

MAJOR RESEARCH INTERESTS

Mechanisms of aging, death, and regeneration in cardiomyocytes

HONORS

The Japan Scholarship Foundation Scholarship for Graduated School Students;2001- 2005

The Banyu Fellowship Program, sponsored by Banyu Life Science Foundation International; 2008 - 2009

Finalist, Louis N. and Arnold M. Katz Basic Research Prize, American Heart Association Scientific Sessions 2011; 2011

Final List, Melvin L. Marcus Young Investigator Award in Cardiovascular Sciences, American Heart Association Scientific Sessions 2012; 2012

GRANTS

Grant-in-aid for scientific research from the Ministry of Education, Science, Sports, and Culture of Japan (18790493); 2006-2007

Sakakibara Memorial Research Grant from The Japan Research Promotion Society for Cardiovascular Diseases; 2007

Travel grant from Basic Cardiovascular Sciences 2009 Scientific Sessions of American Heart Association; 2009

Travel grant from American Heart Association Scientific Sessions 2009; 2009

Travel grant from American Heart Association Scientific Sessions 2010; 2010

National Center Scientist Development Grant, American Heart Association, Winter 2012; 2012-2015

PUBLICATIONS

First Author Publication:

  1. Maejima Y, Kyoi S, Zhai P, Liu T, Li H,Ivessa A, Sciarretta S, Del Re DP, Zablocki D, Hsu CP, Lim DS, Isobe M, Sadoshima J.Mst1 inhibits autophagy by promoting Beclin1-Bcl-2 interaction. Nature Medicine 2013 [In press].
  2. Maejima Y, Galeotti J, Molkentin JD, Sadoshima J, Zhai P. Constitutively active MEK1 rescues cardiac dysfunction caused by overexpressed GSK-3α during aging and hemodynamicpressure overload.Am J Physiol Heart Circ Physiol303:H979-988, 2012.
  3. Usui S*, Maejima Y*, Pain J, Hong C, Cho J, Park JY, Zablocki D, Tian B, Glass DJ, Sadoshima J. Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of NF-kB. Circ Res109: 161-171, 2011. *Equally contribution.
  4. Maejima Y, Okada H, Haraguchi G, Onai Y, Kosuge H, Suzuki J, Hirao K, Isobe M. Telmisartan, a unique ARB, improves left ventricular remodeling after myocardial infarction by activating peroxisome proliferator-activated receptor-γ. Lab Invest91: 932-944, 2011.
  5. Maejima Y, Kuroda J, Matsushima S, Ago T, Sadoshima J. Regulation of myocardial growth and death by NADPH oxidase. J Mol Cell Cardiol50: 408-416, 2011.
  6. Maejima Y,Nobori K, Ono Y, Adachi S, Suzuki J, Hirao K, Isobe M, Ito H;for the heart failure by coadministration of statin and angiotensin-II receptor blocker (HF-COSTAR) trial investigators. Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure - The HF-COSTAR Trial- Circ J75: 589-595, 2011.
  7. Maejima Y, Adachi S, Ito H, Hirao K, Isobe M. Induction of premature senescence in cardiomyocytes by oxidative stress as a novel mechanism of myocardial dysfunction. Aging Cell 7:125-136, 2008.
  8. Maejima Y, Adachi S, Morikawa K, Ito H, Isobe M. Nitric oxide inhibits myocardial apoptosis by preventing caspase-3 activity via S-nitrosylation. J Mol Cell Cardiol 38:163-174, 2005.
  9. Maejima Y, Yasu T, Ueba H, Kobayashi N, Hashimoto S, Kubo N, Kakehashi A, Isobe M, Kawakami M, Saito M. Exercise after heparin administration: new therapeutic program for patients with-option arteriosclerosis oblitrans. Circ J 69: 1099-1104, 2005.
  10. Maejima Y, Yasu T, Ueba H, Kobayashi N, Kuroki M, Kubo N, Fujii M, Saito M.Long-term prognosis of fulminant myocarditis rescued by percutaneous cardiopulmonarysupport device. Circ J68:829-833, 2004.
  11. Maejima Y, Adachi S, Ito H, Nobori K, Tamamori-Adachi M, Isobe M.Nitric oxide inhibits ischemia/reperfusion-induced myocardial apoptosis by modulating cyclinA-associated kinase activity. Cardiovasc Res 59:308-320, 2003.
  12. Maejima Y, Ueba H, Kuroki M, Yasu T, Hashimoto S, Nabata A, Kobayashi N, Ikeda N, Saito M, Kawakami M. Src family kinases and nitric oxide production are required for hepatocyte growth factor-stimulated endothelial cell growth. Atherosclerosis 167:89-95, 2003.
  13. Maejima Y, Yasu T, Fujiwara N, Ishida T, Kobayashi Y, Kuroki M, Kubo N, Fujii M, Saito M. Vasospastic total occlusion at the left main tract in a single coronary artery.Jpn Circ J65:1091-1092, 2001.

Co-Author Publication:

  1. Terao C, Yoshifuji H, Kimura A, Matsumura T, Ohmura K, Takahashi M, Shimizu M, Kawaguchi T, Chen Z, Naruse TK, Sato-Otsubo A, Ebana Y, Maejima Y, Kinoshita H, Murakami K, Kawabata D, Wada Y, Narita I, Tazaki J, Kawaguchi Y, Yamanaka H, Yurugi K, Miura Y, Maekawa T, Ogawa S, Komuro I, Nagai R, Yamada R, Tabara Y, Isobe M, Mimori T, Matsuda F. Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. Am J Hum Genet 2013 Jul 2. doi:pii: S0002-9297(13)00263-2. [Epub ahead of print]
  2. Hariharan N, Ikeda Y, Hong C, Alcendor RR, Usui S, Gao S, Maejima Y, Sadoshima J. Autophagy plays an essential role in mediating regression of hypertrophy during unloading of the heart. PLoS One 8:e51632, 2013.
  3. Sciarretta S, Zhai P, Shao D, Maejima Y, Robbins J, Volpe M, Condorelli G, Sadoshima J. Rheb is a critical regulator of autophagy during myocardial ischemia: Pathophysiological implications in obesity and metabolic syndrome. Circulation 125: 1134-1146, 2012.
  4. Cho J, Zhai P, Maejima Y, Sadoshima J. Myocardial Injection With GSK-3{beta}-overexpressing bone marrow-derived mesenchymal stem cells attenuates cardiac dysfunction after myocardial infarction. Circ Res 108: 478-489, 2011.
  5. Hariharan N, Maejima Y, Nakae J, Paik J, Depinho RA, Sadoshima J. Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-Induced autophagy in cardiac myocytes. Circ Res 107:1470-1482, 2010.
  6. Hsu CP, Zhai P, Yamamoto T, Maejima Y, Matsushima S, Harinaran N, Shao D, Takagi H, Oka S, Sadoshima J. Sirt1 protects the heart from ischemia/reperfusion. Circulation122:2170-2182, 2010.
  7. Takagi H, Hsu CP, Kajimoto K, Shao D, Yang Y, Maejima Y, Zhai P, Yehia G, Yamada C, Zablocki D, Sadoshima J. Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion.Circ Res 107:642-649, 2010.
  8. Suzuki J, OgawaM, TamuraN, MaejimaY, TakayamaK, MaemuraK, HondaK, HirataY, NagaiR, IsobeM. A critical role of sympathetic nerve regulation for the treatment of impaired daily rhythm in hypertensive Dahl rats. Hypertens Res33: 1060-1065, 2010.
  9. Kosuge H, Ishihara T, Haraguchi G, Maejima Y, Okada H, Saiki H, Suzuki J, Isobe M. Treatment with telmisartan attenuates graft arteriosclerosis in murine cardiac allografts. J Heart Lung Transplant 29: 562-567, 2010.
  10. Isobe K, Kuba K, Maejima Y, Suzuki J, Kubota S, Isobe M. Inhibition of endostatin/collagen XVIII deteriorates left ventricular remodeling and heart failure in rat myocardial infarction model. Circ J74: 109-119, 2010.
  11. Gelpi RJ, Gao S, Zhai P, Yan L, Hong C, Danridge LM, Ge H, Maejima Y, Donato M, Yokota M, Molkentin JD, Vatner DE, Vatner SF, Sadoshima J. Genetic inhibition of calcineurin induces diastolic dysfunction in mice with chronic pressure overload. Am J Physiol Heart Circ Physiol297: H1814-H1819, 2009.
  12. Konishi M, Maejima Y, Inagaki H, Haraguchi G, Hachiya H, Suzuki J, Hirao K, Isobe M. Clinical characteristics of acute decompensated heart failure with rapid onset of symptoms. J Card Fail15: 300-304, 2009.
  13. Matsuda T, Zhai P, Maejima Y, Hong C, Gao S, Tian B, Goto K, Takagi H, Tamamori-Adachi M, Kitajima S, Sadoshima J. Distinct roles of GSK-3αand GSK-3β phosphorylation in the heart under pressure overload. Proc Natl Acad Sci U S A105: 20900-20905, 2008.
  14. Haga T, Suzuki J, Kosuge H, Ogawa M, Saiki H, Haraguchi G, Maejima Y, Isobe M, Uede T. Attenuation of experimental autoimmune myocarditis by blocking T cell activation through 4-1BB pathway.J Mol Cell Cardiol 46: 719-727, 2009.
  15. Tamamori-Adaci M, Takagi H, Hashimoto K, Goto K, Hidaka T, Koshimizu U, Yamada K, Goto I, Maejima Y, Isobe M, Nakayama KI, Inomata N, Kitajima S. Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase. Cardiovasc Res80:181-190, 2008.
  16. Karube A, Suzuki J, Haraguchi G, Maejima Y, Saiki H, Kosuge H, Isobe M, Uede T. Suppression of neointimal hyperplasia after vascular injury by blocking 4-1BB/4-1BB ligand pathway. J Med Dent Sci55:207-213, 2008.
  17. Saiki H, Suzuki J, Kosuge H, Haraguchi G, Ishihara T, Maejima Y, Isobe M, Uede T. Blockade of the 4-1BB pathway attenuates graft arterial disease in cardiac allografts. Int Heart J 49: 105-118, 2008.
  18. Haraguchi G, Kosuge H, Maejima Y, Suzuki J Imai T, Yoshida M, Isobe M. Pioglitazone reduces systematic inflammation and improves mortality in apolipoprotein E knockout mice with sepsis. Intensive Care Med 34: 1304-1312, 2008.
  19. Okada H, Suzuki J, Futamatsu H, Maejima Y, Hirao K, Isobe M. Attenuation of autoimmune myocarditis in rats by mesenchymal stem cell transplantation through enhanced expression of hepatocyte growth factor. Int Heart J 48: 649-61, 2007.
  20. Suzuki J, Koga N, Kosuge H, Ogawa M, Haraguchi G, Maejima Y, Saiki H, Isobe M. Pitavastatin suppresses acute and chronic rejection in murine cardiac allografts. Transplantation 83:1093-97, 2007.
  21. Suzuki J, Ogawa M, MaejimaY, Isobe K, Tanaka H, Sagesaka YM, Isobe M. Tea catechins attenuate chronic ventricular remodeling after myocardial ischemia in rats.J Mol Cell Cardiol 42:432-40, 2007.
  22. Onai Y, Suzuki J, Maejima Y, Haraguchi G, Muto S, Itai A, Isobe M. Inhibition of NF-κB improves left ventricular remodeling and cardiac dysfunction after myocardial infarction. Am J Physiol Heart Circ Physiol 292:H530-538, 2007.
  23. Kosuge H, Suzuki JI, Haraguchi G, Koga N, Maejima Y, Inobe M, Isobe M, Uede T.Critical Role of Inducible Costimulator Signaling in the Development of Arteriosclerosis. Arterioscler Thromb Vasc Biol 26: 2660-2665, 2006.
  24. Kosuge H, Haraguchi G, Koga N, Maejima Y, Suzuki J, Isobe M. Pioglitazone prevents acute and chronic cardiac allograft rejection. Circulation 113: 2613-22, 2006.
  25. Futamatsu H, Suzuki J, Koga N, Adachi S, Kosuge H, Maejima Y, Haga T, Hirao K, Horuk R, Isobe M. A CCR1 Antagonist Prevents the Development of Experimental Autoimmune Myocarditis in Association with T Cell Inactivation. J Mol Cell Cardiol40:853-61, 2006.
  26. Morikawa-Futamatsu K, Adachi S, Maejima Y, Tamamori-Adachi M, Suzuki J, Kitajima S, Ito H, Isobe M. HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1. Life Sci 79: 1380-1390, 2006.
  27. Futamatsu H, Suzuki J, Mizuno S, Koga N, Adachi S, Kosuge H, Maejima Y, Hirao K, Nakamura T, Isobe M. Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: a potential role for induction of T helper 2 cytokines. Circ Res 96: 823-30. 2005.
  28. Koga N, Suzuki J, Kosuge H, Haraguchi G, Onai Y, Futamatsu H, Maejima Y, Gotoh R, Saiki H, Tsushima F, Azuma M, Isobe M. The blockade of the interaction between PD-1 and PDL-1 accelerates graft arterial disease in cardiac allografts. Arteriosc Thromb Vasc Biol24: 2057-2062, 2004.
  29. Onai Y, Suzuki J, Kakuta T, Maejima Y, Haraguchi G, Fukasawa H, Muto S, Itai A, Isobe M. Inhibition of IkB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury. Cardiovasc Res 63:51-59, 2004.
  30. Ikeda S, Takabayashi Y, Maejima Y, Tachibana N, Ehara T, Nezu A, Hoshii Y. Nodular lung disease with five year survival and unilateral pleural effusion in AL amyloidosis. Amyloid6:292-296, 1999.

Textbook:

1. Maejima Y, Zablocki D, Sadoshima J. Oxidative stress and cardiac muscle; In: Hill JA, Olson EN, eds. Muscle 1st Edition: Fundamental Biology and Mechanisms and Disease. Elsevier, p.309-322, 2012.

PRESENTATIONS

  1. Maejima Y, Kyoi S, Zhai P, Liu T, Li H, Sadoshima J. Mst1-Mediated Phosphorylation of Beclin1 in its BH3 Domain Promotes Beclin1-Bcl-2 Interaction, Thereby Negatively Regulating Autophagy in the Heart. (2011, Nov.)American Heart Association Scientific Sessions 2011, Final competition of Louis N. and Arnold M. Katz Basic Research Prize for young investigators, Orlando, USA.
  2. Maejima Y, Kyoi S, Zhai P, Sadoshima J. Mst1 Physically Interacts with and Phosphorylates Beclin1, Thereby Negatively Regulating Autophagy in the Heart. (2011, Nov.) American Heart Association Scientific Sessions 2011, Best of AHA Specialty Conferences, Orlando, USA.
  3. Maejima Y, Zhai P, Sadoshima J. GSK-3β Prevents Cardiac Dysfunction through Modulation of FoxO1 Activity Under Pressure Overload. (2011, Nov.) American Heart Association Scientific Sessions 2011, Orlando, USA.
  4. Maejima Y, Zhai P, KunduM, Sadoshima J.Mammalian UNC-51-like Kinase (ULK)-1 Plays a Crucial Role in Mediating Autophagy Under Stress Conditions in the Heart. (2011, Nov.) American Heart Association Scientific Sessions 2011, Orlando, USA.
  5. Maejima Y, Kyoi S, Zhai P, Sadoshima J. Mst1 Physically Interacts with and Phosphorylates Beclin1, Thereby Negatively Regulating Autophagy in the Heart. (2011, Jul.) Basic Cardiovascular Sciences 2011 Scientific Sessions of American Heart Association, New Orleans, USA.
  6. Maejima Y, Zhai P, Sadoshima J. Mst1 Stimulates Cell Protective Mechanisms of FoxO1 Through Phosphorylation in Cardiomyocytes. (2010, Nov.) American Heart Association Scientific Sessions 2010, Chicago, USA.
  7. Maejima Y, Zhai P, Yamamoto T, Matsuda T, Sadoshima J. E2F2/4 Regulated by Serine 21 Phosphorylation of GSK-3α Plays Compensatory RolesUnder Pressure Overload. (2010, Nov.) American Heart Association Scientific Sessions 2010, Chicago, USA.
  8. Maejima Y, Zhai P, Sadoshima J. GSK3β Inhibits Cardiac Hypertrophy through FoxO1, but Protects the Heart fromDysfunction Independently of FoxO1 under Pressure Overload. (2010, Nov.) American Heart Association Scientific Sessions 2010, Chicago, USA.
  9. Maejima Y. Mst1 stimulates cell protective mechanisms of FoxO1 through phophorylation (2010, Oct.) 14th Annual Scientific Meeting of the Japanese Heart Failure Society, Toyot, Japan (Symposium, Invited).
  10. Maejima Y, Isobe M, Sadoshima J. The Mechanism and the Role of Aging in Cardiomyocytes (2010, Mar.) 74th Annual Scientific Meeting of Japanese Circulation Society, Kyoto, Japan (Topics, Invited).
  11. Maejima Y,Sadoshima J.Mst1 Physically Interacts with and Phosphorylates FoxO1, thereby Stimulating Cell Protective Mechanisms of FoxO1 in the Heart(2009, Nov.) American Heart Association Scientific Sessions 2009, Orlando, USA.
  12. Maejima Y, Zhai P, Sadoshima J. GSK3β Negatively Regulates Cardiac Hypertrophy through Activation of FoxO(2009, Nov.) American Heart Association Scientific Sessions 2009, Orlando, USA.
  13. Maejima Y, Sadoshima J. Mst1 Physically Interacts with and Phosphorylates Foxo1, thereby Stimulating Cell Protective Mechanisms of Foxo1 in the Heart(2009, Jul.) Basic Cardiovascular Sciences 2009 Scientific Sessions of American Heart Association, Lake Las Vegas, USA.
  14. Maejima Y, Tamamori-Adachi M, Yamada K, Adachi S, Kitajima S, Isobe M. Important Role of FGF Signaling and p27kip1 in Adult Cardiomyocyte CellCycle Regulation(2008, Nov.) American Heart Association Scientific Sessions 2008, New Orleans, USA.
  15. Maejima Y, Adachi S, Isobe M. Oxidative Stress Induce Myocardial Atrophy by Modulating Nuclear Translocation of FoxO1 Transcription Factor (2008, Mar.) 72nd Annual Scientific Meeting of Japanese Circulation Society, Fukuoka, Japan.
  16. Maejima Y, Adachi S, Isobe K, Ito H, Isobe M. Combined treatment of angiotensin receptor blocker and HMG-CoA reductase inhibitor synergistically improves cardiac dysfunction in Dahl rats. (2007, June) 24thAnnual Meeting of International society for Heart Research Japanese Section, Ferrara, Italy.
  17. Maejima Y, Adachi S, Isobe K, Ito H, Isobe M. Simvastatin Enhances Beneficial Effects of Losartan on Myocardial dysfunction of Salt-Sensitive Hypertensive Rats, via Pleiotropic Effects. (2007, Mar.) 71st Annual Scientific Meeting of Japanese Circulation Society, Yokohama, Japan.
  18. Maejima Y, Adachi S, Ito H, Isobe M. Induction of premature senescence in cardiomyocytes by oxidative stress as a novel mechanism of myocardial dysfunction. (2006, Nov.) American Heart Association Scientific Sessions 2006, Chicago, USA.
  19. Maejima Y, Adachi S, Ito H, Isobe M. Premature senescence can be induced by oxidative stress via PML-p53 acetylation pathway in cardiomyocytes. (2006, Mar.) 70th Annual Scientific Meeting of Japanese Circulation Society, Featured Research Session, Nagoya, Japan.
  20. Maejima Y, Suzuki J, Kosuge H, Inagaki H, Kawabata M, Hachiya H, Hata A, Hirao K, Isobe M. Beneficial effects of HMG-CoA reductase inhibitors (statin) in patients with nonischemic heart failure treated with angiotensin II blockade. (2006, Mar.) 70th Annual Scientific Meeting of Japanese Circulation Society, Nagoya, Japan.
  21. Maejima Y, Adachi S, Morikawa K, Ito H, Isobe M. Senescence-like alterations by oxidative stress is novel mechanism of cardiomyocyte dysfunction. (2005, Mar.) 69th Annual Scientific Meeting of Japanese Circulation Society, Yokohama, Japan.
  22. Maejima Y, Adachi S, Morikawa K, Nobori K, Tamamori-Adachi M, Isobe M, Ito H. Nitric oxide inhibits hypoxia/reoxygenation-induced myocardial apoptosis by modulating cyclin A-associated kinase activity. (2003, Nov.) 76th American Heart Association Scientific Sessions 2003, Orlando, USA.
  23. Maejima Y, Adachi S, Nobori K, Morikawa K, Tamamori-Adachi M, Ito H, Isobe M. Endogenous nitric oxide inhibits hypoxia/reoxygenation-induced myocardial apoptosis with the modulation of cyclin A-associated kinase activity. (2003, Mar.) 67th Annual Scientific Meeting of Japanese Circulation Society, Featured Research Session, Fukuoka, Japan.
  24. Maejima Y, Yasu T, Iwasawa T, Ueba H, Kobayashi N, Hashimoto S, Tsuruya Y, Kubo N, Fujii M, Kawakami M, Saito M, Tsuboi J, Ino T, Kakehashi A. Exercise after heparin administration: A new therapeutic program for patient with arteriosclerosis obliterans. (2002, Nov.) American Heart Association Scientific Sessions 2002, Chicago, USA.
  25. Maejima Y, Ueba H, Kuroki M, Yasu T, Kobayashi N, Nabata A, Hashimoto S, Saito M, Kawakami M. Src family kinases and nitric oxide production are required for hepatocyte growth factor-stimulated endothelial cell growth. (2002, May.) 12th International Vascular Biology Meeting, Karuizawa, Japan.
  26. Maejima Y, Yasu T, Iwasawa T, Ueba H, Kobayashi N, Hashimoto S, Tsuruya Y, Kubo N, Fujii M, Kuroki M, Kawakami M, Saito M, Tsuboi J, Ino T, Kakehashi A. Exercise after heparin administration, a new therapeutic program for patient with arteriosclerosis obliterans. (2002, Apr.) 66th Annual Scientific Meeting of Japanese Circulation Society, Sapporo, Japan.
  27. Maejima Y, Adachi S, Tamamori-Adachi M, Nobori K, Ito H, Isobe M. Nitric oxide inhibits ischemia/reperfusion-induced myocardial apoptosis by suppression of cyclin A-associated kinase activity. (2002, Apr.) 66th Annual Scientific Meeting of Japanese Circulation Society, Sapporo, Japan.
  28. Maejima Y, Ueba H, Kuroki M, Yasu T, Nabata A, Ikeda N, Kobayashi N, Hashimoto S, Saito M, Kawakami M. Nitric oxide production is required for hepatocyte growth factor-stimulated endothelial cell growth. (2001, Mar.) 10th International Symposium of Cardiovascular Pharmacology, Kyoto, Japan.
  29. Maejima Y, Yasu T, Matsushima K, Sugawara Y, Tsuruya Y, Hasimoto S, Kubo N, Omura N, Fujii M, Saito M. Long-term prognosis of fulminant myocarditis rescued by percutaneous cardiopulmonary support device. (2000, Mar.) 65th Annual Scientific Meeting of Japanese Circulation Society, Osaka, Japan.