Class meets Apr 2 to May 23
2013.5 / Course intro / Stuart / Introduction
Course format
Course requirements
1.5hr / Introduction / Human Genetic Variation / Salari_2009*
HamburgSalari_2011*
2 hr / Bioethics presentation
debate: "Should DTC genetic tests by prescription only?" / Rosalind / Put in middle of schedule
2 hr / Linkage
SNPs
Traits
LD blocks
Problem set 1 out / Pearson*
Manolio
GWAS1
GWAS2
GWAS3
1 hr /
GWAS
SNPediaintroduction
2 / Class GWAS
1 / Ancestry
1 / Height vs parents height
/ Workshop / Visscher
0.5 / Whodunit?
1 / Neanderthal evolution
/ Workshop / Green 2010
23andme
2 / Cancer genomics, Breast cancer
0.5?
1? / Genomic Convergence
1 / Human positive selection(Stuart)
1 / Frontiers in human genetics
2 hr / Neurological Disease / Aaron Gitler
Rosalind Chuang / LIll 2011
Lill 2012
Do 2011
2 / Intro to pharm
Russ Altman / Pharmacogenetics / terrific!!!
2 / Atul Butte / Big datasets / Terrific
2 / Mike Snyder / Future tech
2 / Intro to eQTLs
Stephen Montgomery / Expression / Lots of potential to do something creative.
2 / Euan Ashley / Heart / Great talk, but too introductory
2 / Presentations of SNP write-ups
Presentation of class survey (Nate Cira)
Class evaluation
Class Discussion
2 / neonatal sequencing
2 / Psychiatric disorders / Jon Bernstein/Rosa?
Date / Second string / Presenter / Readings
Tue April 2 / Heart Disease / Tim Assimes / CVD2012a*
CVD2012b
CVD2011a
CVD2011b
Thur
April 4 / Interpreting Genomic Data in Clinical Medicine. / Euan Ashley
Evaluation Form
Tue April 9 / Ancestry
Problem set 1 due viaemail(Answers)
Problem set 2 out / Carlos Bustamante / Auton 2009
Bryc 2010
Novembre 2008
Thur April 11 / Carlos Bustamente / Various / Standard research talk, no preparation
Tue
April 16 / Tim Assimes / Heart / Kind of dry
Thur
April 18 / Emmanuel Mignot / Narcolepsy / Interesting, but not really related to class
Tue
April 23
Thur
April 25
Tue
Apr 30
Thur
May 2
Tue
May 7 / Workshop
Thur
May 9
Tue
May 14
Thur
May 16
extra
extra
extra
extra01-5/20)
ent for 23andmeyption factorsd by involving re-setting key developmental regulators in ol. This theory isnt of ch
extra / Workshop
Thur
June 7 / Next generation sequencing.
Final exam out
Extra credit out / Mike Snyder
June 13 / Final exam & extra credit due at midnight viaemail(Answers)
Ideas for advanced projects:
algorithm for efficient sequencing of a population
exome data/analysis of Gitler data?
write an RPGEH grant
analyze Stuart Genome and Aaron.