Southern State Community College

Curriculum Committee – July 2017

CHEM 1124-Elementary Organic Chemistry

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  1. COURSE TITLE:Elementary Organic Chemistry

COURSE NUMBER: 1124CATALOG PREFIX: CHEM

II.PREREQUISITE:High school chemistry or CHEM 1120.

III.CREDIT HOURS:4LECTURE HOURS: 4

LABORATORY HOURS:(lab component)OBSERVATION HOURS:0

IV.COURSE DESCRIPTION:

An introduction to organic chemistry including functional groups and reactions is followed by an investigation ofimportant biochemicals including carbohydrates, proteins, lipids, and enzymes. In addition, nucleic acids and their role in protein synthesis are studied as are neurotransmitters and their role in chemical communication. Desirable for students interested in Allied Health.

V.ADOPTED TEXT(S):

LECTURE:

General, Organic, & Biological Chemistry

3rd Edition

Janice G. Smith

McGraw-Hill

ISBN: 9781309078839

LABORATORY:

VI.COURSE OBJECTIVES:

Upon completion of this course the student should be able to:

  1. Define and recognize structural isomers and stereoisomers,

2.Demonstrate an understanding of the structure and functional groups of alcohols, aldehydes, ketones, ethers, carboxylic acids, esters, amides and amines,

3. Demonstrate an understanding of condensation and hydrolysis reactions,

4.Explain the role of hydrogen bonding in determining the properties of biochemicals,

5.Understand the structures of amino acids and proteins,

6.Explain how the structures of proteins affect their overall shape and function,

7.Discuss the structures and functions of steroids along with those of simple and complex lipids,

8.Explain how enzymes catalyze biochemical reactions,

9.Understand the role of vitamins in enzyme catalysis,

10. Discuss the structures of carbohydrates and their role in the energy cycle of living organisms,

11. Explain the role of neurotransmitters in chemical communication, and

12. Discuss nucleic acids and describe their role in protein synthesis.

VII. COURSE METHODOLOGY

This course will use lecture, Power Point, discussion, home work assignments, laboratory projects, and written exams as deemed appropriate by the instructor.

VIII.GRADING:

A / 90 / – / 100
B / 80 / – / 89
C / 70 / – / 79
D / 60 / – / 69
F / 0 / – / 59

IX.COURSE OUTLINE

  1. Introduction to Organic Chemistry
  1. Definition
  2. Structural Formulas
  3. Functional Groups
  1. Alkanes
  1. Structural Formulas
  2. Isomers
  3. Nomenclature
  4. Cycloalkanes
  5. Shapes of Alkanes and Cycloalkanes
  6. Physical Properties
  7. Chemical Properties
  1. Alkenes and Alkynes
  1. Definition
  2. Structural Formulas
  3. Nomenclature
  4. Physical Properties
  5. Reactions
  6. Polymerization of Ethylene and Substituted Ethylenes
  1. Benzene and Derivatives
  1. The Structure of Benzene
  2. Important Benzene Derivatives
  3. Phenols
  1. Alcohols, Ethers, and Thiols
  1. Structure and Nomenclature
  2. Physical Properties
  3. Chemical Reactions
  4. The Commercial Importance of Alcohols and Ethers
  1. Chirality: The Handedness of Molecules
  1. Enantiomerism
  2. Depicting enantiomers
  3. Stereoisomers of Molecules Having Two or More Stereocenters
  4. Optical Activity and its Role in the Detection of Chirality
  5. The Significance of Chirality in the Biological World
  1. Amines
  1. Definition
  2. Structure and Classification
  3. Physical Properties
  4. Basicity
  1. Aldehydes and Ketones
  1. Definition
  2. Structure
  3. Physical Properties
  4. Reactions
  1. Carboxylic Acids
  1. Definition
  2. Structure
  3. Physical Properties
  4. Fatty Acids
  5. Acidity
  6. Reactions
  1. Esters and Amides
  1. Definition
  2. Structure
  3. Preparation of Esters
  4. Preparation of Amides
  5. Hydrolysis of Esters and Amides
  6. Phosphoric Esters
  1. Carbohydrates
  1. Monosaccharides

(1)D- and L- Monosaccharides

(2)Cyclic Structures

(3)D-Glucose

(4)Reactions

  1. Disaccharides

(1)Sucrose

(2)Maltose

(3)Lactose

  1. Oligosaccharides
  1. Polysaccharides

(1)Starch

(2)Glycogen

(3)Cellulose

  1. Lipids
  1. Triglycerides

(1)Structure

(2)Synthesis

(3)Hydrolysis

(4)Saturated and Unsaturated Fatty Acids

(5)Properties of Fats and Oils

  1. Complex lipids

(1)Structure

(2)Solubility

(3)Role in Cell Membranes

  1. Steroids
  1. Proteins

a.Functions in Living Organisms

b.Amino Acids

(1)Structure and Properties

(2)Zwitterions

(3)Reactions to Form Proteins

c.Peptides

(1)Peptide bonds

(2)Amino Acid Residues

(3)C-terminal and N-terminal amino acids

  1. Proteins

(1) Isoelectric Point

(2)Primary Structure

(3)Secondary Structures

(4)Tertiary Structures

(5)Quaternary Structures

(6)How Structure Affects Protein function

  1. Enzymes

a.The role of enzymes in biochemical reactions

b.Structure

c.Specificity

d.Classification

e.Factors that Influence Enzyme Activity

f.Mechanism of Enzyme Action

  1. Chemical Communication
  1. Definitions

(1)Neurotransmitters

(2)Secondary Messengers

(3)Neurons

(4)Receptors

  1. Classification of Neurotransmitters
  2. Neurotransmission

(1)Receptors

(2)Storage of Messengers

(3)Signal Transduction

(4)Secondary Messengers

(5)Removal of Neurotransmitters

(6)Control of Neurotransmission

  1. Nucleic Acids
  1. Structures of Nucleic Acids
  2. Structures of DNA and RNA
  3. DNA Replication
  4. Classes of RNA
  5. Genes
  6. Protein Synthesis

COURSE CALENDAR

Week # / Chapter
1 / 10 / Organic chemistry
11 / Alkanes
2 / 12 / Alkenes and Alkynes
13 / Benzene and Its Derivatives
3 / 14 / Alcohols, Ethers, and Thiols
4 / 15 / Chirality: The Handedness of Molecules
5 / 16 / Amines
17 / Aldehydes and Ketones
6 / 18 / Carboxylic Acids
19 / Carboxylic Anhydrides, Esters, and Amides
7 / 20 / Carbohydrates
8 / 21 / Lipids
9 / 22 / Proteins
10 / 23 / Enzymes
11 / 24 / Chemical Communications: Neurotransmitters and Hormones
12 / 25 / Nucleotides, Nucleic Acids, and Heredity
26 / Gene Expression and Protein Synthesis
13 / 27 / Bioenergetics: How the Body Converts Food to Energy
14 / 30 / Nutrition
15 / Review
16 / Final

X. OTHER REQUIRED BOOKS, SOFTWARE, AND MATERIALS:

Students are required to purchase laboratory goggles.

XI.EVALUATION:

At the discretion of the instructor.

XII.SPECIFIC MANAGEMENT REQUIREMENTS:

Students may not use programmable calculators or cell phones during exams.

Please understand that your work may be seen by others. Others may see your work when it is being distributed, during group project work, or if it is chosen for demonstration purposes.

Academic Misconduct: Any student who commits any type of misconduct as stated in the current college catalogue will receive an “F” for the exam, quiz, or evaluated project.

XIII. Other Information

FERPA: Students need to understand that your work may be seen by others. Others may see your work when being distributed, during group project work, or if it is chosen for demonstration purposes. Students also need to know that there is a strong possibility that your work may be submitted to other entities for the purpose of plagiarism checks.

DISABILITIES: Students with disabilities may contact the Disabilities Service Office, Central Campus, at 800-628-7722 or 937-393-3431.