GP Masterclass May 11Th 2015 Fiona Brown. Cancer Care Specialist Dietitian

GP Masterclass May 11th 2015 Fiona Brown. Cancer Care Specialist Dietitian.

Nutrition and upper GI cancers

Aim

•  To identify nutritional issues which can be dealt with in primary care and when to refer a patient into the Dietetic service

Objectives

•  Nutritional challenges for patients and implications

•  Intervention

•  Dietetic roles and intervention

General Overview of Malnutrition in UK

Greater use of healthcare and costs associated with malnutrition means: (Mind the hunger Gap 2012)

•  65% more GP visits; 82% more hospital admissions; 30% longer hospital stay.

Costs / Saving opportunities
•  Malnourished patients visiting their GP incur an additional health care cost of £1449 per patient in the year following diagnosis (Guest et al, 2011; Malnutrition Task Force, 2013).
The estimated costs of malnutrition in the UK range from :
•  £5bn for direct health care costs (Guest et al, 2011: Malnutrition Task Force, 2013)
•  To £13bn for associated health and social care expenditure in 2007
(Elia & Russell for BAPEN, 2009) / ·  Screening and early intervention could result in a net saving of £71,800 per 100,000 of the population (National Institute for Health & Care Excellence, 2012).
·  Regular screening and monitoring all people in care homes has been shown to cost half that of treating those who are malnourished (Meijers et al, 2011).
·  Appropriate use of Oral Nutritional Supplements (ONS) in hospitals has been found to save £849 per patient based on length of stay and reduce GP attendances (Elia & Stratton, 2009).

Malnutrition prevalence for upper GI cancers

•  Lung, oesophageal, stomach, pancreatic, colonic, rectal and head and neck cancers carry the greatest presentation of weight loss/nutritional challenges (Capra 2001)

•  upper GI cancer patients malnourished = 52% (Segura et al, 2005)

Screening of nutritional status in 1000 patients (mixed diagnoses) Nutritional risk highest in upper GI cancer patients. Oesophageal cancer patients mean weight loss 16.3 % (16 to 40%). Over half had lost 10% of their weight. Where anorexia is a symptom then the risk of weight loss is higher. When weight loss was more than 10% anorexia occurred in 50% of patients (Bozzetti et al, 2010) Percentages patients severe malnutrition at cancer site were Oesophagus 62.5% Stomach 43.7% Pancreas 54.3% (Bozzetti et al, 2012)

Significance of Malnutrition

•  Poor prognosis
•  Reduced response to anticancer therapy
•  Increased side effects of treatment
•  Weakness, fatigue
•  Reduced quality of life
•  Increased mortality rate
•  Increased hospital stay
•  Treatment may have to be delayed or stopped / •  Problems related to nutrition have been identified as the most important factor in affecting a sense of wellbeing…’ (Padilla et al 1983)
•  ‘Short term nutritional support can improve well being and quality of life.’ (Holmes and Dickerson 1991)

(De Wys 1980, Andreyev 1998, Marin 2007, Holmes 1996), Nayel 1992, Isering 2004, Bauer 2005, Odelli 2005, Braunschweig 2000, Pressoir 2010)

Aims of Nutritional Treatments

·  Preventing and treating undernutrition

·  Enhancing anti-tumour treatment effects

·  Reducing adverse effects of anti-tumour therapies

·  Improving quality of life.

Nutrition intervention needs to be;

Timely (early), Appropriate, Include suitable monitoring and recognised that some patients will require specialist intervention and support perhaps using artificial tube feeding ?parenteral feeding

Pathways
Rehabilitation throughout the treatment pathway delivered by Allied Health Professionals is recognised by NICE,NCAT,Macmillan etc. at;

•  Pre diagnosis
•  Diagnosis and care-planning
•  Treatment
•  Post Treatment
•  Monitoring and Survivorship
•  Palliative Care
•  End of Life
(NCAT Rehabilitation Care Pathway 2009) / •  Pre diagnosis
•  Assessment and Diagnosis
•  Treatment (pre/post XRT, chemo, surgery)
•  Survivorship
(AHP Cancer care toolkit. A guide for
Healthcare Commissioners)

NICE guidance suggests a screening tool should be based on:

•  Measurement of weight and weight history

•  Has there been a normal and varied diet in the last few weeks?

•  Unintentional weight loss?

•  Any swallowing problems?

•  Metabolic stress eg. Wound healing

•  Excessive losses eg. vomiting, diarrhoea

•  Global assessment eg. Any signs of loose fitting clothes/watch

•  Can patient meet their requirements with voluntary choice from the food available

•  Acknowledging that those with High BMI are at risk of malnutrition.

•  Example of screening tool – MUST (National Collaborating Centre for Acute Care, 2006)

Local Pathway

Prescribing Sip feeds in Adults (2013) GHNHSFT in conjunction this Gloucestershire Clinical Commissioning Group available on-line at Gloucestershire ‘CCG Live’ intranet in the section: Clinical support/medicines management/prescribing guidance.

This pathway is based on regular monitoring and assessment;

1.  Nutritional Screening (MUST) including percentage weight loss

2.  Assessing and investigating any underlying causes/barriers to patient maintaining good nutritional status. E.g. underlying medical cause, disease states with nutritional implications, Oral health/swallowing problems, altered taste and smell, reduced mobility, poor positioning, social situation, psychological wellbeing, poly-pharmacy. Refer directly to Dietitians if required

3.  ‘Food First Approach’=first line dietary advice to use; small frequent meal, increase milk intake if possible and fortify/enrich milk and other foods.

4.  Agree and Document goals of treatment

5.  Prescribing Oral Nutritional sip feeds. Fresubin powder initially then 1.5kcal/ml ready to drink feeds dependant on preference.

6.  Refer to other service e.g. Dietitians

Role of Dietitians

•  Nutritional assessment
•  Dietary counselling
•  Advise on specific diets in line with underlying diagnosis(s) and treatment(s)
•  Experts on Prescribed/non-prescribed nutritional supplements, enteral and parenteral feeds
•  Deliver nutritional care in line with treatment side effects including gastric paresis, alterations in digestion, malabsorption of nutrients/bile acids, hyperglycaemia, fluid and electrolyte imbalance, dumping syndrome, and vitamin and mineral deficiencies etc.
•  Provide advice and support with alternative or complementary diets
Benefits of Rehabilitation throughout the pathway
(NCAT (2013) Cancer Rehabilitation, making excellent cancer care possible )
/

Evidence based information for patients available at:

British Dietetic Association

Food fact sheets (online) https://www.bda.uk.com/foodfacts/MalnutritionFactSheet

Macmillan

Nutritional support (enteral tube feeds) http://www.macmillan.org.uk/information-and-support/coping/side-effects-and-symptoms/eating-problems/types-of-nutritional-support.html

Eating problems http://www.macmillan.org.uk/information-and-support/coping/side-effects-and-symptoms/eating-problems

Build up diet http://be.macmillan.org.uk/be/p-20052-the-building-up-diet.aspx

Healthy eating http://www.macmillan.org.uk/information-and-support/coping/maintaining-a-healthy-lifestyle/healthy-eating

Recipe booklet – contact Macmillan by phone

Cancer research

Managing Diet http://www.cancerresearchuk.org/about-cancer/coping-with-cancer/coping-physically/diet/managing/

Oesophageal Patients association

On-line talks on nutrition http://www.opa.org.uk/resources.html

Pancreatic cancer UK

Has on-line details and support on diet at varying stages of the treatment pathway http://www.pancreaticcancer.org.uk/information-and-support/managing-dietary-symptoms/

Please make any Dietetic referrals to:

The Nutrition and Dietetic Dept,
Cheltenham General Hospital
GHNHSFT Tel: 0300422 3460 / The Nutrition and Dietetic Dept,
Beacon House
Gloucestershire Royal Hospital
GHNHSFT Tel: 0300422 5506

References and Bibliography

NICE (2004). Improving Supportive and Palliative Care for Adults with Cancer
NCAT (2009) Cancer and Palliative Care Rehabilitation Workforce Project: A review of the evidence
www.cancerhelp.org.uk
www.asha.org
Carlyle R, et al.(2011) Macmillan Cancer Support. Cancer information pathways literature review.
National Council for Hospice and Specialist Palliative Care. NCHSPCS (2000) Fulfilling Lives. Rehabilitation in palliative care.
Macmillan (2010) Grimes C. Guidance for the Nutritional Management of Cancer Patients
http://www.cancer.nhs.uk (Rehabilitation Workforce Project)
Elliot J, et al (2011) British Journal of Cancer. The health and well-being of cancer survivors in the UK: findings from a population-based survey
Morrison V, et al (2012) European Journal of Oncology Nursing. Common, important, and unmet needs of cancer outpatients
Department of Health. Cancer Patient Experience Survey 2011/12. Q52
DH, Macmillan Cancer Support & NHS Improvement (2010) The National Cancer Survivorship Initiative Vision
NCAT(2010) Cancer and Palliative Care Rehabilitation Workforce Project: Project overview report
Macmillan (2010) Allied Health Professionals in cancer care: An evidence review
Hopkinson, Jane B. (2008) Carers' influence on diets of people with advanced cancer. Nursing Times, 104, (12), 28-29
Capra S, Ferguson M, Ried K. Cancer: impact of nutrition intervention outcome-nutrition issues for patients. Nutrition. 2001;17:769-772.
NCAT (2013) Cancer Rehabilitation, making excellent cancer care possible
http://webarchive.nationalarchives.gov.uk/20130513211237/http:/www.ncat.nhs.uk/sites/default/files/work-docs/Cancer_rehab-making_excellent_cancer_care_possible.2013.pdf
British Dietetic Association (2012) mind the Hunger gap
Multi-professional consensus panel. Managing Adult Malnutrition in the community (2012)
BAPEN (2003) The MUST report. National Screening for Adults:A multidiscaplinary responsibility.
National Institute for Health and Clinical Excellence (NICE) Clinical Guideline 32: Nutrition support in adults. NICE 2006
NHS London on behalf of the Strategic AHP Leads Group (SAHPLE) Allied Health Professions Cancer care toolkit. How AHPs improve patient care and save the NHS money
NHS England (2014) Commissioning guidance for oesophageal and gastric cancers http://www.england.nhs.uk/commissioning/wp-content/uploads/sites/12/2014/03/b11-cancer-oesop-gast.pdf
Bozetti et al (2012) The nutritional risk in oncology: a study of 1,453 cancer outpatients. Support Care Cancer 20:1919–1928
Andreyev JHN, Norman AR, Oates J, Cunningham D. Why do patients with weight loss have a worse
outcome when undergoing chemotherapy for gastrointestinal malignancies? Eur J Cancer. 1998;34:503-509
Arends J, Bodoky G, Bozzetti F et al ESPEN Guidelines on enteral Nutrition:Non surgical oncology. (2006) Clinical Nutrition
DeWys WD, Begg C, Lavin PT et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am J Med. 1980;69:491-497.
Holmes and Dickerson 1991 Preliminary investigations of symptom distress in two cancer patient populations. Journal of Advanced Nursing 16,439-446
Iestra J, Fibbe WE, Zwinderman AH, van Staveren W A, Kromhout D. (2002) Body weight recovery, eating
difficulties and compliance with dietary advice in the first five years after stem cell transplantation:
a prospective study. Bone Marrow Transplantation 1, 29, 5, p417-424
Isenring EA, Capra S, Bauer JD. (2004)Nutrition intervention is beneficial in oncology outpatients receiving
radiotherapy to the gastrointestinal or head and neck area. Br J Cancer.;91:447-452.
Marin Caro MM, Laviano A, Pichard C. Nutritional intervention and quality of life in adult oncology
patients. Clin Nutr. 2007;26:289-301
Senesse P, Assenat E, Schneider SM, et al. Nutritional support during curative treatment of patients with gastrointestinal(GI) cancer: who could benefit? Cancer Treat Rev 2008;34: 568—75
Odelli C, Burgess D, Bateman L et al. Nutrition support improves patient outcomes, treatment
tolerance and admission characteristics in oesophageal cancer. Clin Oncol. 2005;17:639-645.
Padilla et al 1983 Quality of life index for patients with cancer. Res. Nurs. Hlth., 6, 117

3