Appendix VI

Research

VI.2Faculty Research Awards

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Appendix VI.2

Awards
Faculty Research Initiatives Fund
Faculty Innovation Fund
Technology Transfer Seed Grant

1

Appendix VI.2

Faculty Research Initiatives Fund Awards

Title / Primary Investigator (PI)
and Co-Investigators / Department, School, University
2003
Preparatory Study for East Baltimore Survey of Health and Health Care Utilization / Bernard Guyer, MD (PI) / Population and Family Health Sciences
Cheryl Alexander, PhD / Population and Family Health Sciences
Jacquelyn C. Campbell, PhD / School of Nursing
Tina L. Cheng, MD, MPH / Pediatrics, School of Medicine
Jean G. Ford, MD / Epidemiology and Oncology, School of Medicine
Claude Earl Fox, MD, MPH / Director, Urban Institute
Michael C. Gibbons, MD, MPH / Urban Institute
Tobey A Gordon, ScD / Vice President for Strategic Planning and MarketResearchJohnsHopkinsHospital
Sandra Newman, PhD / Health Policy and Management and Director, Institute for Policy Studies, JohnsHopkinsUniversity
Jonathan Zenilman, MD / School of Medicine
2003
Neighborhood Characteristics, Stress, and Prostate Cancer / Greg Glass, PhD (PI) / Molecular Microbiology and Immunology
Craig Newshaffer, PhD / Epidemiology
Elizabeth Platz, PhD / Epidemiology
2004
Intervention and Instrument Development for a Community-based Trial to Prevent Diabetes Risk Behaviors in First Nations and American Indian Communities / Joel Gittelsohn, PhD (PI) / International Health
Kevin D. Frick, PhD / Health Policy and Management
Tiffany L. Gary, PhD / Epidemiology
Rajiv Rimal, PhD / Health Policy and Management
Margarita Treuth, PhD / International Health
Steward Harris, MD, MPH / International Health
Alexandra Admas, MD, PHD / University of Wisconsin
Sangita Sharma, PhD / University of Hawaii
2004
Molecular Mechanism of Double-Strand Break Repair Inactivation by Adenovirus Oncoproteins / Leslyn Hanakahi, PhD / Biochemistry and Molecular Biology
Gary W. Ketner, PhD / Molecular Microbiology and Immunology
2004
Carcinogens in Biosolids as Determinants of Human Morbidity and Mortality / Rolf Halden, PhD / Environmental Health Sciences
Norma F. Kanarek / Environmental Health Sciences and Oncology, School of Medicine
Elizabeth A. Platz, ScD, MPH / Epidemiology

Faculty Research Initiatives Fund Awards, continued

Title / Primary Investigator (PI)
and Co-Investigators / Department, School, University
2004
Proteomic Approaches for the Discovery of Novel Serum Indicators of Micronutrient Status / Keith P. West, PhD / International Health
James Yager, PhD / Environmental Health Sciences
Ingu Ruczinski, PhD / Biostatistics
2005
Evaluation of the New Urine Malaria Dipstick Test in Pemba / David Sullivan, MD / Molecular Microbiology and Immunology
2005
A Benchmark for Microarray Data Analysis Methodology / Rafael Irizarry, PhD / Biostatistics
2005
Novel Peptide-Oligonucleotide Analogues to Inhibit HIV-I Replication / Clara L. Kielkopf, PhD / Biochemistry and Molecular Microbiology
Paul Miller / Biochemistry and Molecular Microbiology
Karen L. Beemon, PhD / Biology, JohnsHopkinsUniversity
2005
Development of Algorithms to Analyze High Density SNP Array Data in Patients with
Chromosomal Abnormalities / Ingo Ruczinski, PhD / Biostatistics
Jonathan Pevsner, PhD / Molecular Neurobiology, Kennedy Krieger Institute and Department of Neuroscience
Karl Broman, PhD / Biostatistics

Faculty Innovation Fund Awards

Title / Faculty Investigator / Department
1999
“What State Policies Help Youth Avoid Risky Behavior? / David Bishai * / International Health
Cancer Control Needs of New Immigrant Populations in Maryland / Ann C. Klassen * / Health Policy and Management
Applications of Modern Time Series Techniques in the Biomedical Sciences / Rafael A. Irizarry * / Biostatistics
Characterization of an Adhesive Protein from Toxoplasma gondii Using Gene Synthesis and Mammalian Cell Expression / Vern Carruthers * / Molecular Microbiology and Immunology
Youth Wisdom Study / Debra Mekos / Population and Family Health Sciences
Molecular Mechanisms by which Environmental Toxins Disrupt Neuronal Morphogenesis / Pamela J. Lein / Environmental Health Sciences
SUMO-1 Modification and Regulation of Nucleocytoplasmic Transport / Michael J. Matunis * / Biochemistry and Molecular Biology
2000
Signaling Mechanisms that Control Oocyte Development / Janice Evans * / Biochemistry and Molecular Biology
Designs and Analyses to Address Deviations from Protocol in Studies for Cancer and Other Outcomes on Public Health / Constantine Frangakis * / Biostatistics
Molecular Mechanisms by which Environmental Toxins Disrupt Neuronal Morphogenesis / Pamela J. Lein / Environmental Health Sciences
Errors in Ambulatory Medication Use: Risk Factors and Implications / Alan Lyles * / Health Policy and Management
Genetic Heterogeneity among Populations of Ticks and Tick-Borne Pathogens in Baltimore County, MD / Douglas Norris * / Molecular Microbiology and Immunology
Prostate Cancer Aggressiveness and Survival / Elizabeth Platz * / Epidemiology
Soy and Hot Flushes: A Double Blind, Randomized Dietary Supplementation Feasibility Study / Ellen Smit / Epidemiology
2001
Applications of Tree-based Models to Identify Epistatic Interactions between QTLs in Model Organisms / Karl W. Broman * / Biostatistics
Development of the SCID-hu Thy/Liv Mouse as a Novel Animal Model for Dengue Infection/Dengue Hemmorrhagic Fever and Dengue Shock Syndrome / Anna P. Durbin / International Health
Heavy Metal and Cardiovascular Risk in the Clue / Daniele Fallin / Epidemiology

Faculty Innovation Fund Awards, continued

Title / Faculty Investigator / Department
Development of Database Information for Assessment of the Effects of Cattle Farming on Pollution of the WyeRiver, Chesapeake Bay, MD / Thaddeus Graczyk * / Molecular Microbiology and Immunology
Heavy Metal and Cardiovascular Risk in the Clue / Eliseo Guallar / Epidemiology
Mechanisms of Measles Virus Suppression of HIV Replication / William Moss / Molecular Microbiology and Immunology
2002
Monte Carlo and MarkovChain Monte Carlo Algorithms for Conditional and Random Effect Models for Categorical Data / Brian S. Caffo / Biostatistics
Environmental Sources, Occurrence and Biodegradation of the Biocide Triclosan / Rolf Halden / Environmental Health Sciences
Prevention of HIV Among Russian Injection Drug Users / William Latimer * / Mental Health
Maternal Depressive Symptoms and Children’s Use of Health Care Services: A Pilot Study / Cynthia Minkovitz * / Population and Family Health Sciences
Using All-atom Potentials to Improve Ab Initio Protein Structure Prediction / Ingo Ruczinski / Biostatistics
A Novel Strategy Linking Variation in Gene Structure and Expression to Physiological Diversity / ClarkeTankersley * / Environmental Health Sciences
Selecting High Risk Families to Detect Modifier Genes in FAP Patients / Yin Yao / Epidemiology
2003
Impact of Topical Therapy with Neucream on Skin Barrier Function in Preterm Infants / Gary L.Darmstadt * / International Health
Development and Validation of Assays to Measure HPV 16 Gene Expression from Human Exfoliated Cervical Cells / PattiGravitt / Epidemiology
Identification of the Molecular Machinery for Cell Fusion / EricGrote / Biochemistry and Molecular Biology
Studying Genetic Susceptibility to Obesity, Type 2 Diabetes, and Chronic Kidney Disease in Multi-ethnic Representation Sample of the US Adult Population / LindaKao / Epidemiology
Unusual U2AF Features for RNA Trans-Splicing: A Novel Target of Anti-Parasitic Drugs / ClaraKielkopf / Biochemistry and Molecular Biology
Household Regimes of Production and Consumption, Access to Cash, and Health in the Context of the Chad-Cameroon Petroleum Development and Pipeline Project / LoriLeonard / International Health
Biochemical and Biophysical Characterization of Low Complexity Regions in Malaria Proteins / SeanPrigge / Molecular Microbiology and Immunology

Faculty Innovation Fund Awards, continued

Title / Faculty Investigator / Department
2004
Moderate Kidney Dysfunction, Anemia, and Coronary Calcification in the Multi-Ethnic Study of Atherosclerosis (MESA) / Brad Astor / Epidemiology
Analysis of Cholesterol Homeostasis in Toxoplasma-infected Cells / Isabelle Coppens / Molecular Microbiology and Immunology
Development of an Anopheles Gambiae / Plasmodium Berghei Microarray / George Dimopoulos / Molecular Microbiology and Immunology
The Molecular Mechanism of DNA Repair by Ku-Dependent Non-Homologous End-Joining in Mammals: A Target for Anti-Cancer Agents / Leslyn Hanakahi / Biochemistry and Molecular Biology
New Methods of Estimation and Sensitivity Analysis for Causal Inferences in Observational Studies / Zhiqiang Tan / Biostatistics
Segregation Analysis of NPC / Yin Yao / Epidemiology
2005
Single Nucleotide Polymorphisms and in vivoHuman IL-10 Regulation: Characterization of a Transgenic Mouse Model / Jay Bream / International Health
Accounting for Model Uncertainty in Epidemiology / Ciprian Crainiceanu / Biostatistics
cAMP-dependant Regulation of Type III Secretion of Yersinia enterocolitica / Egbert Hoiczyk / Molecular Microbiology and Immunology
Identifying Proteomic Patterns Associated with Loss of T-cell Homeostasis in HIV-1 Infection / Gregory D. Kirk / Epidemiology
Feeling Loved or Unloved: A Cross-cultural Comparison of Parent-Adolescent Relationships and Adolescent Health Risk Behavior / Clea A. McNeely / Population and Family Health Sciences
New Media Coverage of Progress in Cancer Science and Treatment / Katherine Clegg Smith / Health Policy and Management
* Indicates promotion to Associate Professor

Technology Transfer Seed Grant Awards

Technology / Description / Faculty / Department
2000 – 2001
Immunization 21-A Guide to Immunization in the 21st Century (Educational CD-ROM Project) / CD-Rom project that will provide training and up-to-date information for health care professionals who administer injections, with emphasis on immunizations / Neal Halsey / International Health
Analytical System / Produce commercial instruments designed for a convenient (but accurate) non-invasive method for the collection of human breath for profiling and analysis / Terence Risby / Environmental Health Sciences
2001 – 2002
Development of a Business Plan For Licensing the PraPlus / Question form and assessment for repeat admissions of medical care / Chad Boult / Health Policy and Management
Law-RIS / Research Information System/ Internet System for Assessing Autistic Children / Paul Law / International Health
Commercialization of Targeted Dietary Research and Advisory Sciences In Hypertension and Prenatal Nutrition through Collaborative
Development of Rules-Based Prototype / Fee-based Web site that provides accurate, useful personalized information to enhance the health and wellness of individuals with specific medical and dietary needs / Ben Caballero / International Health
Software for Evidence-based
Reviews in Prevention / Reporting tool / Neil Powe / Epidemiology
2003 – 2004
Production and Testing of in situ Microcosm Array Prototype / Instrument designed to manage contaminated groundwater and soil sites, and perform risk assessments of microorganisms into a natural environment / Rolf Halden / Environmental Health Sciences
Continued Development
Continuous Operation / Apparatus for the separation of
cystic parasite forms from water / Clive Shiff
and
Thaddeus Graczyk / Molecular Microbiology and Immunology
Global Environment / Research the linkages between human health and the natural world;research and teach through understanding and appreciation of preserving natural resources by educating the next generation of the threats of global ecological degradation / Jonathan Patz / Environmental Health Sciences
Down-Well Diagnostic
Device for Environmental Restoration / Health status assessment instrument for adolescents aged 11-17, to report on their own health / Rolf Halden / Environmental Health Sciences

Technology Transfer Seed Grant Awards, continued

Technology / Description / Faculty / Department
Support for the Transfer of New Technology: The CHIP Health Status Instruments / Survey instrument to measure health status of children 6-17 / Anne Riley / Health Policy and Management
2004 – 2005
Malaria Diagnostic Assay / Urine dipstick to test for malaria / David Sullivan / Molecular Microbiology and Immunology
Anti-Cancer Therapeutic / To identify compounds that modulate the repair of DNA double-strand breaks / Leslyn Hanakahi / Biochemistry and Molecular Biology
Detection and Control of Schistosome Cercariae / Define drugs, dose, and method of delivery / Jean Naples and
Clive Shiff / Molecular Microbiology and Immunology
Approach for Tackling Cancer Chemo-Resistance / Tackle chemo-resistance cancers and improve efficacy of drugs / Shyam Biswal / Environmental Health Sciences
Project Sugar / Algorithms addressing the following areas: blood glucose control, blood pressure control, lipid control, depressive symptoms, smoking, foot screening, blood glucose monitoring, socioeconomic issues, alcohol use, and illicit drug use / Tiffany Gary / Epidemiology
2005 – 2006
Lactobacilli Expressing anti-ICAM-1 as an anti-HIV-1
Microbicide / Agents similar to spermicides that can inhibit HIV-1 transmission when applied inter-vaginally prior to intercourse / Richard Markham / Molecular Microbiology and Immunology
Portable Dark Adaptometer / A device for the field examination and detection of night blindness / Alain Labrique / International Health
Feasibility Study for
Mitigating ongoing Product
Ddevelopment for the ACG Case Mix System into an EnterpriseExternal to JHU / ACG- is a software tool for risk adjustment of health care resource use / John Weiner / Health Policy and Management

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Appendix VI.2