MAJOR DEPRESSIVE DISORDER AND ITALIAN NEUROLOGISTS’ PERCEPTION
Section 1
a) Birth Year: I__|__I__|__I
b) Gender: 〇 Male 〇 Female
c) Year in which you started your neurological practice: I__|__I__|__I
d) Region of residence: ______
e) Clinical activity location:
¨ University hospital / ¨ Hospital ward / ¨ Public outpatient service / ¨ Private outpatient service / ¨ Private clinicf) Which neurological diseases do you manage most frequently?
¨ Dementias
¨ Movement Disorders
¨ Multiple Sclerosis
¨ SLA and neuromuscolar diseases
¨ Cerebrovascular diseases
¨ Epilepsy
¨ Headaches
¨ Other
If other, specify:
______
g) On average, how many patients do you see per month? I__|__I__|__I
h) Estimated at 100 the number of patients you see per month, how many of these are affected by major depressive disorder (MDD) (specify the approximate percentage)? I__|__I__| %
i) Estimated at 100 the number of patients with MDD you see per month, how many of these are over 65 years old? (specify the approximate percentage)? I__|__I__| %
j) Estimated at 100 the number of patients with MDD, how many of these have MDD as primary diagnosis? (specify the approximate percentage)? I__|__I__| %
k) Estimated at 100 the number of patients with neurological disease as primary diagnosis, how many of these have a MDD comorbidity (specify the approximate percentage)? I__|__I__| %
l) What priority do you give to the treatment of MDD in patients with neurological disease as primary diagnosis and with a MDD comorbidity?
〇 Lower priority than the neurological disease
〇 The same priority as the neurological disease
〇 Higher priority than the neurological disease
Section 2
Kind Doctor, please answer to the following questions based on your experience and your clinical practice.
1) Based on your experience, put the symptoms listed in order of importance (from the most important to the less important) to define the presence of a MDE (Major Depressive Episode) in MDD:
- Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
- Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
- Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
- Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
- Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
- Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).
- Fatigue or loss of energy nearly every day.
- Insomnia or hypersomnia nearly every day.
- Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
2) Based on your experience, which of the following symptoms most influence the choice of one antidepressant over another? (Please, order the symptoms listed from the most influential to the less influential).
- Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
- Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
- Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
- Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
- Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
- Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).
- Fatigue or loss of energy nearly every day.
- Insomnia or hypersomnia nearly every day.
- Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
3) Based on your experience, which of the following symptoms may most affect the functioning of patient with MDD? (Please, order the symptoms listed from the symptom that most affect the functioning to the one that less affect the functioning of the patient)
- Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
- Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
- Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
- Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
- Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
- Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).
- Fatigue or loss of energy nearly every day.
- Insomnia or hypersomnia nearly every day.
- Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
4) Based on your experience, which of the following symptoms may improve adhesion to antidepressant therapy once resolved? (Please, order the symptoms listed from the most important to the less important):
- Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
- Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
- Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
- Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
- Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
- Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).
- Fatigue or loss of energy nearly every day.
- Insomnia or hypersomnia nearly every day.
- Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
5) Based on your experience, which of the following symptoms may provide improvements to the concurrent neurological condition once resolved? (Please, order the symptoms listed from the most important to the less important):
- Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
- Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
- Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
- Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
- Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
- Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).
- Fatigue or loss of energy nearly every day.
- Insomnia or hypersomnia nearly every day.
- Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
6) Based on your experience, which of the following symptoms could be common to both depression and dementias? (flag one or more symptoms)
¨ Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
¨ Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
¨ Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
¨ Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
¨ Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
¨ Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).
¨ Fatigue or loss of energy nearly every day.
¨ Insomnia or hypersomnia nearly every day.
¨ Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
¨ None of the symptoms above mentioned.
7) Based on your experience, which of the following symptoms could be common to both depression and movement disorders? (flag one or more symptoms)
¨ Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
¨ Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
¨ Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
¨ Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
¨ Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
¨ Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).
¨ Fatigue or loss of energy nearly every day.
¨ Insomnia or hypersomnia nearly every day.
¨ Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
¨ None of the symptoms above mentioned.
8) Based on your experience, which of the following symptoms could be common to both depression and cerebrovascular diseases? (flag one or more symptoms)
¨ Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
¨ Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
¨ Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
¨ Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
¨ Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
¨ Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).
¨ Fatigue or loss of energy nearly every day.
¨ Insomnia or hypersomnia nearly every day.
¨ Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
¨ None of the symptoms above mentioned.
9) Based on your experience, which of the following symptoms could be common to both depression and multiple sclerosis? (flag one or more symptoms)
¨ Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.
¨ Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others).
¨ Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others).
¨ Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
¨ Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful).
¨ Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down).