Electronic Table

Electronic Table

Relative risk of cancer by gender in those tested positive for BRCA mutations and in those not tested but assumed positive.

Study Subjects / Observed / Expected / Relative Risk / Confidence Intervals (95%)
All Cancers
BRCA1
Females
Index tested positive (1) / 10 / 12.9 / 0.8 / 0.4-1.4
First degree tested positive (2) / 8 / 10.9 / 0.7 / 0.3-1.4
Total tested positive (1+2) / 18 / 23.9 / 0.8 / 0.5-1.2
Not tested assumed positive (3) / 15.0 / 13.0 / 1.2 / 0.7-1.9
total tested and assumed positive (1+2+3) / 33.0 / 36.9 / 0.9 / 0.6-1.3
Males
Index tested positive (1) / 0 / 0.6 / 0.0
First degree tested positive (2) / 10 / 13.2 / 0.8 / 0.4-1.4
Total tested positive (1+2) / 10 / 13.8 / 0.7 / 0.4-1.3
Not tested assumed positive (3) / 11.4 / 29.6 / 0.4 / 0.2-0.7
total tested and assumed positive (1+2+3) / 21.4 / 43.4 / 0.5 / 0.3-0.8
BRCA2
Females
Index tested positive (1) / 12 / 11.0 / 1.1 / 0.6-1.9
First degree tested positive (2) / 9 / 8.6 / 1.0 / 0.5-2.0
Total tested positive (1+2) / 21 / 19.6 / 1.1 / 0.7-1.6
Not tested assumed positive (3) / 11.9 / 13.1 / 0.9 / 0.5-1.6
total tested and assumed positive (1+2+3) / 32.9 / 32.7 / 1.0 / 0.7-1.4
Males
Index tested positive (1) / 5 / 1.9 / 2.6 / 0.8-6.0
First degree tested positive (2) / 21 / 10.4 / 2.0 / 1.2-3.1
Total tested positive (1+2) / 26 / 12.4 / 2.1 / 1.4-3.1
Not tested assumed positive (3) / 46.8 / 25.2 / 1.9 / 1.4-2.5
total tested and assumed positive (1+2+3) / 72.8 / 37.6 / 1.9 / 1.5-2.4
Oesophagus
BRCA1
Females
Index tested positive (1) / 0 / 0.3 / 0.0
First degree tested positive (2) / 1 / 0.3 / 3.8 / 0.1-21.3
Total tested positive (1+2) / 1 / 0.5 / 1.9 / 0.0-10.4
Not tested assumed positive (3) / 0.7 / 0.3 / 2.0 / 0.0-15.0
total tested and assumed positive (1+2+3) / 1.7 / 0.9 / 1.9 / 0.2-7.7
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.4 / 0.0
Total tested positive (1+2) / 0 / 0.4 / 0.0
Not tested assumed positive (3) / 5.1 / 0.9 / 5.3 / 1.7-12.4
total tested and assumed positive (1+2+3) / 5.1 / 1.4 / 3.7 / 1.2-8.6
BRCA2
Females
Index tested positive (1) / 1 / 0.3 / 3.8
First degree tested positive (2) / 0 / 0.3 / 0.0
Total tested positive (1+2) / 1 / 0.5 / 2.1 / 0.0-11.9
Not tested assumed positive (3) / 1.6 / 0.4 / 4.7 / 0.4-18.8
total tested and assumed positive (1+2+3) / 2.6 / 0.8 / 3.2 / 0.6-10.0
Males
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 2 / 0.4 / 5.5 / 0.6-19.7
Total tested positive (1+2) / 2 / 0.4 / 4.5 / 0.5-16.2
Not tested assumed positive (3) / 4.2 / 0.8 / 5.1 / 1.4-12.8
total tested and assumed positive (1+2+3) / 6.2 / 1.3 / 4.9 / 1.8-10.5
Stomach
BRCA1
Females
Index tested positive (1) / 0 / 0.5 / 0.0
First degree tested positive (2) / 1 / 0.5 / 1.9 / 0.0-10.8
Total tested positive (1+2) / 1 / 1.0 / 1.0 / 0.0-5.6
Not tested assumed positive (3) / 7.4 / 0.6 / 11.5 / 4.8-23.4
total tested and assumed positive (1+2+3) / 8.4 / 1.6 / 5.1 / 2.3-10.0
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 2 / 0.9 / 2.3 / 0.3-8.5
Total tested positive (1+2) / 2 / 0.9 / 2.3 / 0.3-8.2
Not tested assumed positive (3) / 0.0 / 1.9 / 0.0
total tested and assumed positive (1+2+3) / 2.0 / 2.8 / 0.7 / 0.1-2.6
BRCA2
Females
Index tested positive (1) / 0 / 0.4 / 0.0
First degree tested positive (2) / 2 / 0.4 / 5.5 / 0.6-19.8
Total tested positive (1+2) / 2 / 0.8 / 2.5 / 0.3-9.2
Not tested assumed positive (3) / 0.4 / 0.6 / 0.6 / 0.0-7.1
total tested and assumed positive (1+2+3) / 2.4 / 1.4 / 1.7 / 0.3-5.5
Males
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 2 / 0.8 / 2.5 / 0.3-9.2
Total tested positive (1+2) / 2 / 0.9 / 2.2 / 0.2-7.8
Not tested assumed positive (3) / 6.3 / 1.7 / 3.8 / 1.4-8.1
total tested and assumed positive (1+2+3) / 8.3 / 2.6 / 3.2 / 1.4-6.2
Gall Bladder & Bile Duct
BRCA1
Females
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 0 / 0.1 / 0.0
Total tested positive (1+2) / 0 / 0.2 / 0.0
Not tested assumed positive (3) / 0.0 / 0.1 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.3 / 0.0
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 1 / 0.1 / 18.0 / 0.2-100.2
Total tested positive (1+2) / 1 / 0.1 / 17.3 / 0.2-96.1
Not tested assumed positive (3) / 0.0 / 0.1 / 0.0
total tested and assumed positive (1+2+3) / 1.0 / 0.2 / 5.4 / 0.1-30.3
BRCA2
Females
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 0 / 0.1 / 0.0
Total tested positive (1+2) / 0 / 0.1 / 0.0
Not tested assumed positive (3) / 0.0 / 0.1 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.2 / 0.0
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.1 / 0.0
Total tested positive (1+2) / 0 / 0.1 / 0.0
Not tested assumed positive (3) / 1.9 / 0.1 / 17.0 / 1.7-63.3
total tested and assumed positive (1+2+3) / 1.9 / 0.2 / 11.1 / 1.1-41.3
Pancreas
BRCA1
Females
Index tested positive (1) / 1 / 0.4 / 2.7
First degree tested positive (2) / 0 / 0.3 / 0.0
Total tested positive (1+2) / 1 / 0.7 / 1.4 / 0.0-7.7
Not tested assumed positive (3) / 0.6 / 0.4 / 1.3 / 0.0-10.9
total tested and assumed positive (1+2+3) / 1.6 / 1.2 / 1.4 / 0.1-5.6
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.4 / 0.0
Total tested positive (1+2) / 0 / 0.4 / 0.0
Not tested assumed positive (3) / 0.2 / 0.8 / 0.2 / -0.3-5.0
total tested and assumed positive (1+2+3) / 0.2 / 1.2 / 0.2 / -0.2-3.4
BRCA2
Females
Index tested positive (1) / 0 / 0.3 / 0.0
First degree tested positive (2) / 0 / 0.3 / 0.0
Total tested positive (1+2) / 0 / 0.6 / 0.0
Not tested assumed positive (3) / 3.6 / 0.4 / 8.0 / 1.9-21.6
total tested and assumed positive (1+2+3) / 3.6 / 1.0 / 3.4 / 0.8-9.2
Males
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 1 / 0.3 / 3.1 / 0.0-17.2
Total tested positive (1+2) / 1 / 0.4 / 2.6 / 0.0-14.5
Not tested assumed positive (3) / 4.3 / 0.7 / 6.0 / 1.7-15.0
total tested and assumed positive (1+2+3) / 5.3 / 1.1 / 4.8 / 1.6-11.0
Cutaneous Melanoma
BRCA1
Females
Index tested positive (1) / 0 / 0.7 / 0.0
First degree tested positive (2) / 1 / 0.6 / 1.7 / 0.0-9.7
Total tested positive (1+2) / 1 / 1.3 / 0.8 / 0.0-4.2
Not tested assumed positive (3) / 1.4 / 0.6 / 2.4 / 0.1-10.8
total tested and assumed positive (1+2+3) / 2.4 / 1.9 / 1.3 / 0.2-4.1
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.2 / 0.0
Total tested positive (1+2) / 0 / 0.2 / 0.0
Not tested assumed positive (3) / 0.0 / 0.5 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.7 / 0.0
BRCA2
Females
Index tested positive (1) / 0 / 0.6 / 0.0
First degree tested positive (2) / 0 / 0.5 / 0.0
Total tested positive (1+2) / 0 / 1.1 / 0.0
Not tested assumed positive (3) / 2.4 / 0.6 / 4.3 / 0.7-13.9
total tested and assumed positive (1+2+3) / 2.4 / 1.7 / 1.4 / 0.2-4.6
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.1 / 0.0
Total tested positive (1+2) / 0 / 0.2 / 0.0
Not tested assumed positive (3) / 3.6 / 0.4 / 8.6 / 2.1-23.1
total tested and assumed positive (1+2+3) / 3.6 / 0.6 / 6.1 / 1.5-16.5
Uveal Melanoma
BRCA1
Females
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.0 / 0.0
Total tested positive (1+2) / 0 / 0.0 / 0.0
Not tested assumed positive (3) / 0.0 / 0.0 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.0 / 0.0
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.0 / 0.0
Total tested positive (1+2) / 0 / 0.0 / 0.0
Not tested assumed positive (3) / 0.0 / 0.0 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.0 / 0.0
BRCA2
Females
Index tested positive (1) / 1 / 0.0 / 252.1
First degree tested positive (2) / 1 / 0.0 / 346.7 / 4.5-1929.0
Total tested positive (1+2) / 2 / 0.0 / 291.9 / 32.8-1054.1
Not tested assumed positive (3) / 0.0 / 0.0
total tested and assumed positive (1+2+3) / 2.0 / 0.0 / 191.9 / 21.5-693.4
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.0 / 0.0
Total tested positive (1+2) / 0 / 0.0 / 0.0
Not tested assumed positive (3) / 0.0 / 0.0 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.0 / 0.0
Prostate
BRCA1
Males
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 1 / 1.9 / 0.5 / 0.0-3.0
Total tested positive (1+2) / 1 / 2.0 / 0.5 / 0.0-2.8
Not tested assumed positive (3) / 5.1 / 3.9 / 1.3 / 0.4-3.1
total tested and assumed positive (1+2+3) / 6.1 / 5.8 / 1.0 / 0.4-2.3
BRCA2
Males
Index tested positive (1) / 3 / 0.3 / 10.2
First degree tested positive (2) / 9 / 1.4 / 6.3 / 2.9-12.0
Total tested positive (1+2) / 12 / 1.7 / 7.0 / 3.6-12.2
Not tested assumed positive (3) / 19.7 / 3.3 / 6.0 / 3.7-9.3
total tested and assumed positive (1+2+3) / 31.7 / 5.0 / 6.3 / 4.3-9.0
Haematological
BRCA1
Females
Index tested positive (1) / 0 / 1.2 / 0.0
First degree tested positive (2) / 1 / 1.0 / 1.0 / 0.0-5.6
Total tested positive (1+2) / 1 / 2.2 / 0.5 / 0.0-2.5
Not tested assumed positive (3) / 1.9 / 1.1 / 1.6 / 0.2-6.1
total tested and assumed positive (1+2+3) / 2.9 / 3.3 / 0.9 / 0.2-2.6
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 1 / 0.9 / 1.2 / 0.0-6.5
Total tested positive (1+2) / 1 / 0.9 / 1.1 / 0.0-6.2
Not tested assumed positive (3) / 2.7 / 2.3 / 1.2 / 0.2-3.6
total tested and assumed positive (1+2+3) / 3.7 / 3.2 / 1.1 / 0.3-3.1
BRCA2
Females
Index tested positive (1) / 0 / 1.0 / 0.0
First degree tested positive (2) / 1 / 0.8 / 1.2 / 0.0-6.4
Total tested positive (1+2) / 1 / 1.9 / 0.5 / 0.0-3.0
Not tested assumed positive (3) / 0.0 / 1.1 / 0.0
total tested and assumed positive (1+2+3) / 1.0 / 3.0 / 0.3 / 0.0-1.9
Males
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 0 / 0.8 / 0.0
Total tested positive (1+2) / 0 / 0.9 / 0.0
Not tested assumed positive (3) / 0.0 / 2.0 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 2.9 / 0.0
Colorectal
BRCA1
Females
Index tested positive (1) / 2 / 1.8 / 1.1
First degree tested positive (2) / 0 / 1.7 / 0.0
Total tested positive (1+2) / 2 / 3.5 / 0.6 / 0.1-2.1
Not tested assumed positive (3) / 4.0 / 2.1 / 1.9 / 0.5-5.0
total tested and assumed positive (1+2+3) / 6.0 / 5.5 / 1.1 / 0.4-2.4
Males
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 2 / 1.8 / 1.1 / 0.1-4.1
Total tested positive (1+2) / 2 / 1.8 / 1.1 / 0.1-3.9
Not tested assumed positive (3) / 3.0 / 4.0 / 0.7 / 0.2-2.2
total tested and assumed positive (1+2+3) / 5.0 / 5.8 / 0.9 / 0.3-2.0
BRCA2
Females
Index tested positive (1) / 3 / 1.6 / 1.9
First degree tested positive (2) / 1 / 1.2 / 0.8 / 0.0-4.5
Total tested positive (1+2) / 4 / 2.9 / 1.4 / 0.4-3.6
Not tested assumed positive (3) / 4.9 / 2.1 / 2.4 / 0.8-5.6
total tested and assumed positive (1+2+3) / 8.9 / 4.9 / 1.8 / 0.8-3.5
Males
Index tested positive (1) / 0 / 0.3 / 0.0
First degree tested positive (2) / 1 / 1.6 / 0.6 / 0.0-3.6
Total tested positive (1+2) / 1 / 1.9 / 0.5 / 0.0-2.9
Not tested assumed positive (3) / 0.5 / 3.5 / 0.1 / 0.0-1.3
total tested and assumed positive (1+2+3) / 1.5 / 5.4 / 0.3 / 0.0-1.2
Larynx
BRCA1
Females
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 0 / 0.1 / 0.0
Total tested positive (1+2) / 0 / 0.2 / 0.0
Not tested assumed positive (3) / 0.9 / 0.1 / 10.5 / 0.1-62.3
total tested and assumed positive (1+2+3) / 0.9 / 0.2 / 3.7 / 0.0-21.8
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.2 / 0.0
Total tested positive (1+2) / 0 / 0.2 / 0.0
Not tested assumed positive (3) / 0.0 / 0.6 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.8 / 0.0
BRCA2
Females
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 0 / 0.1 / 0.0
Total tested positive (1+2) / 0 / 0.1 / 0.0
Not tested assumed positive (3) / 0.0 / 0.1 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.2 / 0.0
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.2 / 0.0
Total tested positive (1+2) / 0 / 0.3 / 0.0
Not tested assumed positive (3) / 0.0 / 0.5 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.8 / 0.0
Trachea, Bronchus & Lung
BRCA1
Females
Index tested positive (1) / 0 / 2.0 / 0.0
First degree tested positive (2) / 1 / 1.5 / 0.6 / 0.0-3.6
Total tested positive (1+2) / 1 / 3.6 / 0.3 / 0.0-1.6
Not tested assumed positive (3) / 1.0 / 2.0 / 0.5 / 0.0-2.8
total tested and assumed positive (1+2+3) / 2.0 / 5.6 / 0.4 / 0.0-1.3
Males
Index tested positive (1) / 0 / 0.1 / 0.0
First degree tested positive (2) / 3 / 2.7 / 1.1 / 0.2-3.3
Total tested positive (1+2) / 3 / 2.8 / 1.1 / 0.2-3.1
Not tested assumed positive (3) / 3.2 / 5.8 / 0.6 / 0.1-1.6
total tested and assumed positive (1+2+3) / 6.2 / 8.6 / 0.7 / 0.3-1.6
BRCA2
Females
Index tested positive (1) / 2 / 1.8 / 1.1
First degree tested positive (2) / 0 / 1.3 / 0.0
Total tested positive (1+2) / 2 / 3.1 / 0.7 / 0.1-2.4
Not tested assumed positive (3) / 0.0 / 2.1 / 0.0
total tested and assumed positive (1+2+3) / 2.0 / 5.2 / 0.4 / 0.0-1.4
Males
Index tested positive (1) / 1 / 0.5 / 1.9
First degree tested positive (2) / 3 / 2.4 / 1.2 / 0.3-3.6
Total tested positive (1+2) / 4 / 2.9 / 1.4 / 0.4-3.5
Not tested assumed positive (3) / 4.9 / 5.1 / 1.0 / 0.3-2.3
total tested and assumed positive (1+2+3) / 8.9 / 8.0 / 1.1 / 0.5-2.1
Cervix
BRCA1
Females
Index tested positive (1) / 0 / 1.5 / 0.0
First degree tested positive (2) / 0 / 1.2 / 0.0
Total tested positive (1+2) / 0 / 2.7 / 0.0
Not tested assumed positive (3) / 1.8 / 1.2 / 1.4 / 0.1-5.6
total tested and assumed positive (1+2+3) / 1.8 / 4.0 / 0.4 / 0.0-1.7
BRCA2
Females
Index tested positive (1) / 0 / 1.3 / 0.0
First degree tested positive (2) / 1 / 1.1 / 0.9 / 0.0-5.3
Total tested positive (1+2) / 1 / 2.3 / 0.4 / 0.0-2.4
Not tested assumed positive (3) / 0.8 / 1.2 / 0.7 / 0.0-4.4
total tested and assumed positive (1+2+3) / 1.8 / 3.5 / 0.5 / 0.1-2.0
Body of Uterus
BRCA1
Females
Index tested positive (1) / 3 / 0.8 / 3.7 / 0.8-10.9
First degree tested positive (2) / 1 / 0.6 / 1.7 / 0.0-9.3
Total tested positive (1+2) / 4 / 1.4 / 2.8 / 0.8-7.3
Not tested assumed positive (3) / 0.3 / 0.7 / 0.4 / -0.1-5.8
total tested and assumed positive (1+2+3) / 4.3 / 2.1 / 2.0 / 0.6-5.0
BRCA2
Females
Index tested positive (1) / 3 / 0.7 / 4.2 / 0.8-12.2
First degree tested positive (2) / 1 / 0.5 / 2.0 / 0.0-11.2
Total tested positive (1+2) / 4 / 1.2 / 3.3 / 0.9-8.4
Not tested assumed positive (3) / 0.0 / 0.7 / 0.0
total tested and assumed positive (1+2+3) / 4.0 / 2.0 / 2.0 / 0.6-5.2
Urinary Bladder
BRCA1
Females
Index tested positive (1) / 2 / 0.4 / 4.7
First degree tested positive (2) / 1 / 0.4 / 2.6 / 0.0-14.2
Total tested positive (1+2) / 3 / 0.8 / 3.7 / 0.7-10.7
Not tested assumed positive (3) / 0.0 / 0.5 / 0.0
total tested and assumed positive (1+2+3) / 3.0 / 1.3 / 2.3 / 0.5-6.6
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 1 / 1.0 / 1.1 / 0.0-5.9
Total tested positive (1+2) / 1 / 1.0 / 1.0 / 0.0-5.6
Not tested assumed positive (3) / 0.0 / 2.1 / 0.0
total tested and assumed positive (1+2+3) / 1.0 / 3.1 / 0.3 / 0.0-1.8
BRCA2
Females
Index tested positive (1) / 0 / 0.4 / 0.0
First degree tested positive (2) / 0 / 0.3 / 0.0
Total tested positive (1+2) / 0 / 0.7 / 0.0
Not tested assumed positive (3) / 0.0 / 0.5 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 1.2 / 0.0
Males
Index tested positive (1) / 1 / 0.2 / 6.3
First degree tested positive (2) / 1 / 0.9 / 1.2 / 0.0-6.5
Total tested positive (1+2) / 2 / 1.0 / 2.0 / 0.2-7.1
Not tested assumed positive (3) / 0.0 / 1.8 / 0.0
total tested and assumed positive (1+2+3) / 2.0 / 2.9 / 0.7 / 0.1-2.5
Brain
BRCA1
Females
Index tested positive (1) / 0 / 0.3 / 0.0
First degree tested positive (2) / 0 / 0.3 / 0.0
Total tested positive (1+2) / 0 / 0.6 / 0.0
Not tested assumed positive (3) / 0.7 / 0.3 / 2.3 / 0.0-16.6
total tested and assumed positive (1+2+3) / 0.7 / 0.9 / 0.8 / 0.0-5.4
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.2 / 0.0
Total tested positive (1+2) / 0 / 0.2 / 0.0
Not tested assumed positive (3) / 0.0 / 0.6 / 0.0
total tested and assumed positive (1+2+3) / 0.0 / 0.8 / 0.0
BRCA2
Females
Index tested positive (1) / 0 / 0.3 / 0.0
First degree tested positive (2) / 0 / 0.2 / 0.0
Total tested positive (1+2) / 0 / 0.5 / 0.0
Not tested assumed positive (3) / 0.7 / 0.3 / 2.3 / 0.0-16.8
total tested and assumed positive (1+2+3) / 0.7 / 0.8 / 0.8 / 0.0-6.0
Males
Index tested positive (1) / 0 / 0.0 / 0.0
First degree tested positive (2) / 0 / 0.2 / 0.0
Total tested positive (1+2) / 0 / 0.2 / 0.0
Not tested assumed positive (3) / 0.5 / 0.5 / 1.0 / 0.0-9.4
total tested and assumed positive (1+2+3) / 0.5 / 0.7 / 0.7 / 0.0-6.5