Electronic Supplementary Material

Modelling the size and polydispersity of magnetic hybrid nanoparticles for luminescent sensing of oxygen

Marta Marín-Suárez1*, María C. Arias-Martos1, Jorge F. Fernández-Sánchez1, Teresa Galeano-Díaz2, Alberto Fernández-Gutiérrez1

1 Department of Analytical Chemistry, University of Granada, Avda. Fuentenueva s/n, 18071 Granada (Spain)

2 Department of Analytical Chemistry, University of Extremadura, Avda. de Elvas s/n, 06071 Badajoz (Spain)

* Corresponding authors. Tel.: +34 958 249510; fax: +34 958243328.

E-mail addresses: (M. Marín-Suárez);

Tables:

Table ESM-1. Plackett-Burman design model matrix (Screening test) and results.

Table ESM-1. Central composite design model matrix and results.

Table ESM-3. β coefficient of the second-order polynomial equations

Figures.

Fig. ESM-1. Stern-Volmer plots of the magnetic oxygen sensing nanoparticles.

Table ESM-1. Plackett-Burman design model matrix for the screening test, where the values of the factors are given by − (minus) for low level and + (plus) for high level. Actual values for the levels are shown in Table 1.

Exp. / Mw(g·mol-1) / Cp (mg mL-1) / V (mL) / CSDS (mg mL-1) / A (%) / t (min) / d (nm) / PdI
T1 / − / + / + / − / − / + / 78.72 / 0.185
T2 / + / − / − / − / + / − / 173.9 / 0.202
T3 / + / + / + / − / + / + / 302.3 / 0.473
T4 / − / − / − / + / + / + / 469.1 / 0.563
T5 / + / − / + / + / − / + / 196.2 / 0.223
T6 / − / + / − / − / − / − / 886.1 / 0.648
T7 / − / − / + / + / + / − / 170.0 / 0.125
T8 / + / − / − / + / − / − / 302.9 / 0.443

Table ESM-2. Central composite design matrix for the selected variables (V and Cp) and their corresponding d and PdI of nanoparticle based on the three kind of polymers.

Exp. No. / V (mL) / Cp (mg mL-1) / Polymer 1 / Polymer 2 / Polymer 3
d (nm) / PdI / d (nm) / PdI / d (nm) / PdI
D1 / 6.90 / 32.00 / 213.9 / 0.145 / 189 / 0.145 / 159.1 / 0.11
D2 / 4.25 / 85.25 / 251.4 / 0.216 / 220.6 / 0.199 / 146.5 / 0.111
D3 / 7.99 / 85.25 / 323.7 / 0.295 / 270.3 / 0.239 / 195.4 / 0.108
D4 / 1.60 / 32.00 / 138.8 / 0.100 / 135.9 / 0.115 / 101.9 / 0.12
D5 / 6.90 / 138.50 / 289.8 / 0.287 / 256.1 / 0.253 / 194.6 / 0.162
D6 / 4.25 / 85.25 / 258.5 / 0.245 / 259.7 / 0.223 / 142.9 / 0.090
D7 / 1.60 / 13.50 / 211.9 / 0.242 / 197.9 / 0.199 / 120.7 / 0.110
D8 / 4.25 / 10.17 / 138.4 / 0.109 / 123.8 / 0.126 / 104.8 / 0.118
D9 / 4.25 / 85.25 / 258.4 / 0.250 / 241.7 / 0.224 / 142.8 / 0.089
D10 / 0.51 / 85.25 / 241.4 / 0.342 / 174.9 / 0.193 / 133.1 / 0.141
D11 / 4.25 / 160.33 / 210.8 / 0.228 / 230.0 / 0.255 / 181.0 / 0.136

Table ESM-3. β coefficient of the second-order polynomial equations obtained from the Response Surface Methodology for each type of polymer and response.

Polymer 1 / Polymer 2 / Polymer 3
d / PdI / RF / d / PdI / RF / d / PdI / RF
β0 / 256.16 / 0.237 / -47.39 / 240.69 / 0.215 / -37.18 / 144.10 / 9.63·10-2 / 117.47
β1 / 12.73 / 1.12·10-3 / -13.17 / 11.63 / 7.04·10-3 / -12.41 / 10.36 / -2.14·10-4 / -16.49
β2 / 0.59 / 1.06·10-3 / -0.82 / 0.66 / 8.80·10-4 / -0.88 / 0.38 / 1.59·10-4 / -0.65
β11 / 4.96·10-3 / -3.07·10-10 / 0.157 / 9.04·10-3 / 4.25·10-5 / 8.831·10-2 / 2.96·10-2 / 1.10·10-4 / -8.571·10-2
β22 / 1.36 / 4.03·10-3 / -0.170 / -1.47 / -8.61·10-4 / 1.654 / 1.10 / 2.00·10-3 / -3.841
β12 / -1.58·10-2 / -1.66·10-5 / 1.835·10-2 / -1.17·10-2 / -6.66·10-6 / 1.565·10-2 / -1.06·10-3 / 5.40·10-6 / -1.896·10-3

Fig ESM-1. Stern-Volmer plot for the magnetic oxygen sensing particles obtained for each polymer.