CERTIFICATION

We certify that the thesis titled “Organochlorine Pesticide Residues in Shellfishes and Finfishes from Lagos Lagoon” is an original work carried out by Mr. Akan Bassey Williams (CUGP040105) in the Department of Chemistry, Covenant University, Ota, Ogun State under the supervision of Dr. Olusegun Ayejuyo and Prof. M. Adediran Mesubi.We have examined and found the work acceptable for the award of a degree of Doctor of Philosophy in Environmental Chemistry.

Dr. Olusegun Ayejuyo Signature / Date …………………..

(Supervisor)

Department of Chemistry,

University of Lagos.

Prof. M. Adediran Mesubi Signature / Date …………………..

(Co-Supervisor)

Head, Department of Chemistry,

Covenant University.

Prof. Percy Onianwa Signature / Date……………………

(External Examiner)

Department of Chemistry,

University of Ibadan.

Prof. Fredrick Hymore Signature / Date……………………

Dean, College of Science & Technology

Covenant University.

DEDICATION

This thesis is dedicated to the Almighty God, my creator and provider. To Him alone be all the praise and adoration.

ACKNOWLEDGEMENT

I return the glory to God for enabling me to complete this research. I am indebted to my Supervisor, Dr. Olusegun Ayejuyo and to my co-Supervisor, Prof. M. Adediran Mesubi, for their guidance. The Chancellor of Covenant University, Dr. David Oyedepo, the Board of Regents, the Vice-Chancellor, Prof. Aize Obayan, the Deputy Vice-Chancellor, Prof. Charles Ogbulogo, the pioneer Registrar, Pastor Yemi Nathaniel, and the former Registrar, Dr. Daniel Rotimi, deserve my deep appreciation. Apart from providing the research platform, the gas chromatograph used for the analyses was purchased by the University at great cost to facilitate my work. The Dean, School of Post Graduate Studies, Prof. Chris Awonuga is appreciated. The Dean, College of Science and Technology, Prof. Fredrick Hymore; the immediate past Dean, Prof. James Katende; the Deputy Dean, School of Natural and Applied Sciences, Prof. Louis Egwari, and my immediate past Head of Department, Prof. JohnBull Echeme, have been very supportive.

My external examiner, Prof. Percy Onianwa is deeply appreciated for his scholarly contribution. The mentoring roles of Prof. Oladele Osibanjo, Prof. Olukayode Bamgbose and Prof. Toyin Arowolo are acknowledged. I appreciate my assessors, Prof. Olubode Ajayi, Prof. Kehinde Okonjo and Dr. Aderemi Ogunfowokanfor their constructive assessment.Also, the input of Prof. Samuel Adefila, Prof. BabatundeElemo, Prof. Josiah Bello, Prof. Adeleke Adeniyi, Prof. Emil Asuquo, Prof. Kenneth Adekalu, Dr. Ife Adewumi, Dr. George Ofunne, Dr. Joe Essien, Dr. Mfon Udoh, Dr. Nsikak Benson, Mr. John Paul Unyimadu, Messrs Attah, Emmanuel, Elegbede, Hanson, Ogamba and assistance of Dr.OlayiwolaAfolayan, Dr. Obasola Fagade, Dr. Victor Fodeke, Olukayode Philips, AyorindeFalomo, AbbeyAjireloja and Olatunde Ogunleye have been helpful. I treasure the friendship and encouragement from Dr. Idara Akpabio, Dr. Ekanem Etuk, Dr. Akan Udom, Dr. Ken Opara and Dr. Goddy Akpan. I am indebted to the Environmental Chemistry Research Group (ENCREG) and the entire Faculty and Staff of the Department of Chemistry for their support. My colleagues in the University are also acknowledged. I appreciate the prayers from the Pastorate and membership of Living Faith Church. I deeply appreciate my lovely wife, Mrs Lifted Williams for her love, prayers and assistance in identifying and dissecting the fish organs. I also appreciate my mother, Mrs Akon Williams for her prayers. My siblings and relations are hereby acknowledged.

Williams Akan Bassey

TABLE OF CONTENTS

TITLE PAGE ...... ………………………………………………………………...... i

CERTIFICATION ...…………………………………………………………………...... ii

DEDICATION………………………………………………………………………….....iii

ACKNOWLEDGEMENT……………………………………………………………...... iv

TABLE OF CONTENTS …………………………………………………………...... v

LIST OF TABLES ...…………………………………………………………………...... x

LIST OF FIGURES ...... …………………………………………………………...... xvi

LIST OF PLATES …………………………………………………………………….....xvii

LIST OF ACRONYMS AND ABBREVIATIONS……………………………………..xix

ABSTRACT ...... ………………………………………………………………...... xxiii

CHAPTER ONE

1.0 Introduction…………………………………………………………………….....1

1.1 Introduction to Pesticides...... 1

1.2 Introduction to Fishery Resources in Lagos Lagoon...... 3

1.3 Background of the Study ………………………………………………………....4

1.4 Statement of the Problem………………………………………………………....7

1.5 Justification forthe Study………………………………………………………...7

1.6 Aim of the Study...... ………………………………………………………....9

1.7 Objectives of the Study……………………………………………………...... 10

1.8 Limitations of the Study...... 10

CHAPTER TWO

2.0 Literature Review……………………………………………………………...... 11

2.1 Review of Previous Studies on OCPs in Water, Sediment and Fishes...... 11

2.2 Lagoon Ecosystem ……………………………………………………………....15

2.2.1 Types of Lagoon…………………………………………………………...... 17

2.2.1.1 Coastal Lagoons…………………………………………………………...... 17

2.2.1.2 Estuaries…………………………………………………………………...... 18

2.3 Finfishes……… ……………………………………………………………....19

2.3.1 Classification of Fishes ……………………………………………….…...... 19

2.3.2 Tilapia……………………………………………………………………...... 20

2.3.3 Mullet (Liza grandisquamis)………………………………………………...... 22

2.3.4 Cat Fish (Chrysichthys nigrodigitatus)……………………………………...... 22

2.3.5 Bonga Fish (Ethmalosa fimbriata)……………………………………...... 23

2.3.6 African Moony (Psettias sebae)…………………………………………….....23

2.4 Shellfishes...... 23

2.4.1 Crabs...... 24

2.4.2 Shrimps...... 24

2.4.3 Prawns...... 25

2.4.4 Crayfishes...... 25

2.5 Persistent Organic Pollutants……………………………………………….....26

2.5.1 Classification of Persistent Organic Pollutants…………………………...... 26

2.5.1.1 Polycyclic Aromatic Hydrocarbons (PAHs)……………………………...... 26

2.5.1.2 Halogenated Hydrocarbons………………………………………………...... 27

2.5.1.2.1 Organochlorine Pesticides (OCPs)………………………………………...... 27

2.5.1.2.1.1 Dichlorodiphenyltrichloroethane (DDT)………………………………...... 29

2.5.1.2.1.2 Benzene Hexachloride (BHC)…………………………………………...... 31

2.5.1.2.1.3 Hexachloro Benzene (HCB)……………………………………………….....32

2.5.1.2.1.4 Chlordane………………………………………………………………...... 33

2.5.1.2.1.5 Aldrin……………………………………………………………………...... 33

2.5.1.2.1.6 Dieldrin...... 34

2.5.1.2.1.7 Endrin…………………………………………………………………...... 34

2.5.1.2.1.8 Heptachlor………………………………………………………………….....35

2.5.1.2.1.9 Endosulfan………………………………………………………………...... 36

2.5.1.2.1.10 Methoxychlor…………………………………………………………...... 37

2.5.1.2.1.11 Mirex…………………………………………………………………...... 38

2.5.1.2.1.12 Dioxins……………………………………………………………………...... 38

2.5.1.2.1.13 Furans…………………………………………………………………...... 39

2.5.1.2.1.14 Toxaphene……………………………………………………………...... 40

2.5.1.2.2 Polychlorinated Biphenyls (PCBs)……………………………………...... 41

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Bottom of Form

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2.5.2 Environmental Behaviour and Fate of Persistent Organic Pollutants……....43

2.5.2.1 Fate Processes of Pesticides…………………………………………...... 44

2.5.3 Chemistry and Toxicology of Persistent Organic Pollutants……...... 49

2.5.3.1 Chemistry of Persistent Organic Pollutants…………………………...... 49

2.5.3.2 Toxicology of Persistent Organic Pollutants……………………...... 50

2.6 Analytical Methods of OCP Determination...... 51

2.6.1 Gas Chromatograph coupled with Electron Capture Detector (GC-ECD)....52

2.6.2 Gas Chromatograph coupled with Mass Spectrometer (GC-MS)...... 52

2.6.3 Enzyme-linked Immunoabsorbent Assays (ELISAs)...... 53

2.7 Chromatography………………………………………………...... 54

2.7.1 Chromatographic Mechanisms…………………………………...... 54

2.7.2 Forms of Chromatography……………………………………….……...... 55

2.7.2.1 Gas Chromatography…………………………………………………...... 56

2.7.2.1.1 Gas Chromatographic Components………………………...... 57

2.7.2.1.1.1 Carrier Gas………………………………………………….….…...... 58

2.7.2.1.1.2 Sample-injection System……………………………………………...... 58

2.7.2.1.1.3 Gas-chromatographic Columns………………………………………...... 59

2.7.2.1.1.4 Stationary Phase……………………………………………………...... 61

2.7.2.1.1.5 Liquid Phase………………………………………………………...... 62

2.7.2.1.1.6 Temperature Control……………………………………………...... 62

2.7.2.1.1.7 Detectors…………………………………………………………...... 64

2.7.2.1.1.7.1 Electron Capture Detector (ECD)…………………………………….…...... 65

2.7.2.1.1.7.2 Flame-ionization Detector (FID)………………………………………...... 66

2.7.2.1.1.7.3 Thermal Conductivity Detector (TCD)………………………………...... 67

2.7.2.1.1.7.4 Thermionic Ionization Detector (TID)…………………………………...... 67

2.7.2.1.1.7.5 Flame Photometric Detector (FPD)……………………………………...... 68

2.7.2.1.1.7.6 Photo Ionization Detector (PID)………………………………………...... 68

2.7.2.1.1.7.7 Electrolytic Conductivity Detector (EICD)…………………………...... 69

2.7.2.1.1.7.8 Chemiluminescence–redox Detector………………………………….....70

2.7.2.1.1.8 Use of Chromatograms for Gas Chromatographic Analyses………….....70

2.7.2.1.1.8.1 Qualitative Analysis…………………………………………….…...... 71

2.7.2.1.1.8.2 Quantitative Analysis……………………………………………...... 71

2.7.2.1.1.8.2.1 Geometric Methods…………………………………………………...... 71

2.7.2.1.1.8.2.2 Automatic Integration………………………………………………...... 72

2.7.2.1.1.8.2.3 Evaluation Methods……………………………………………...... 72

2.7.2.1.1.8.2.3.1 Calibration by Standards……………………………………………...... 72

2.7.2.1.1.8.2.3.2 Area Normalization…………………………………………...... 72

2.7.2.1.1.8.2.3.3 Internal Standard……………………………………………………...... 73

2.7.2.1.1.8.2.3.4 Standard Addition…………………………………….………...... 73

2.7.3 Applications of Chromatography…………………………….………...... 74

CHAPTER THREE

3.0 Materials and Methods…………………………………………………………...... 75

3.1 Study Area……………………………………………………………………...... 75

3.2 Sampling Strategy……………………………………………………………...... 75

3.2.1 Pre-treatment of Sampling and Storage Vessels...... 77

3.2.2 Collection of Water Samples…………………………………………………...... 77

3.2.3 Collection of Sediment Samples……………………………………………...... 77

3.2.4 Collection of Fish Samples…………………………………………………...... 78

3.3 Determination of Physicochemical Properties of Water...... ……...... 80

3.3.1 Colour…………………………………………………………………………...... 80

3.3.2 Odour…………………………………………………………………………...... 80

3.3.3 Temperature…………………………………………………………………...... 80

3.3.4 pH……………………………………………………………………………...... 80

3.3.5 Conductivity…………………………………………………………………...... 80

3.3.6 Total Dissolved Solids (TDS)………………………………………….…...... 80

3.3.7 Salinity……………………………………………………………………...... 81

3.3.8 Turbidity……………………………………………………………………...... 81

3.4 Evaluation of Sediment Particle Sizes…………………………………………...... 81

3.5 Characterization of Fishes…………………………………………………...... 81

3.5.1 Determination of Sex…………………………………………………………...... 81

3.5.2 Measurement of Length……………………………………………………...... 82

3.5.3 Evaluation of Percentage Dry Matter……………………………………………...82

3.5.4 Calculation of Condition Factor………………………………………………...... 82

3.5.5 Determination of Fat Content………………………………………...... 82

3.6 Treatment of Samples for Determination of OCP...... 83

3.6.1 Extraction of Water Samples for Determination of OCP...... 83

3.6.2 Extraction of Sediment Samples for Determination of OCP...... 83

3.6.3 Extraction of Fish Samples for Determination of OCP...... 83

3.6.4 Pre-concentration of Extracts...... 84

3.6.5 Clean-up of Extracts...... 84

3.7 Identification and Determination of OCP Residues by Gas Chromatography...... 84

3.8 Quality Assurance...... 86

3.8.1 Recovery Study...... 86

3.8.2 Determination of Method Detection Limits (MDLs)...... 86

3.9 Determination of Limit of Detection (LOD)...... 87

3.10 Determination of Limit of Quantification (LOQ)...... 87

3.11 Determination of Bioconcentration Factor (BCF) andBiota-Sediment

Accumulation Factor (BSAF)...... 87

3.12 Estimation of Daily Intakes(EDI) of Organochlorine Pesticide Residues by

Humans...... 87

3.13 Analyses of Data...... 88

CHAPTER FOUR

4.0 Results and Discussion ...... ……………………………………………89

4.1 Conclusion…………………………………………………………………...... 151

4.2 Recommendations…………………………………………………………...... 152

REFERENCES………………………………………………………………………...... 153

APPENDICES………………………………………………………………………...... 168

LIST OF TABLES

Table 2.1: Classification of the Phylum Chordata…………….………………...... 20

Table 2.2: Structural Classification of Organochlorine Insecticides…………...... 29

Table 3.1: Sampled Finfishes for the Determination of OCP Residues...... 79

Table 3.2: Sampled Shellfishes for the Determination of OCP Residues...... 79

Table 3.3: Operating Conditions of the Gas Chromatograph...... 85

Table 4.1: Mean Values of Physicochemical Properties of Microlayer Water

during the Dry and Wet Seasons…………...... 89

Table 4.2: Mean Values of Physicochemical Properties of Mixed Layer Water

during the Dry and Wet Seasons...... 90

Table 4.3: Comparative Statistics of Physicochemical Properties of Microlayer

Water in Agboyi, Oworonshoki, Ajara, Ogogoro and Tarkwa Bay

during the Dry Season...... 91

Table 4.4: Correlations among Physicochemical Properties of Microlayer Water

in Agboyi Oworonshoki, Ajara, Ogogoro and Tarkwa Bay during the

DrySeason...... 91

Table 4.5: Comparative Statistics of Physicochemical Properties of Microlayer

Water in Agboyi, Oworonshoki, Ajara, Ogogoro and Tarkwa Bay

during the Wet Season...... 92

Table 4.6: Correlations among Physicochemical Properties of Microlayer Water

in Agboyi Oworonshoki, Ajara, Ogogoro and Tarkwa Bay during the

Wet Season...... 92

Table 4.7: Comparative Statistics of Physicochemical Properties of Mixed Layer

Water in Agboyi, Oworonshoki, Ajara, Ogogoro and Tarkwa Bay

during the Dry Season...... 93

Table 4.8: Correlations among Physicochemical Properties of Mixed Layer Water

in Agboyi Oworonshoki, Ajara, Ogogoro and Tarkwa Bay during the

Dry Season...... 93

Table 4.9: Comparative Statistics of Physicochemical Properties of Mixed Layer

Water inAgboyi, Oworonshoki, Ajara, Ogogoro and Tarkwa Bay

during the Wet Season...... 94

Table 4.10: Correlations among Physicochemical Properties of Mixed Layer

Water in Agboyi Oworonshoki, Ajara, Ogogoro and Tarkwa Bay

during the Wet Season...... 94

Table 4.11: Mean Values of Properties of Epipellic Sediment during the Dry

and Wet Seasons……...... 95

Table 4.12: Mean Values of Properties of Benthic Sediment during the Dry

and Wet Seasons………...... 95

Table 4.13: Mean Biometric Data of Finfishes in Agboyi Creekduring the Dry

Season...... 96

Table 4.14: Mean Biometric Data of Finfishes in Agboyi Creekduring the Wet

Season...... 96

Table 4.15: Mean Biometric Data of Finfishes in Lagos Lagoonduring the Dry

Season...... 97

Table 4.16: Mean Biometric Data of Finfishes in Lagos Lagoonduring the Wet

Season...... 98

Table 4.17: Mean Biometric Data of Shellfishes in Agboyi Creekduring the Dry

Season...... 99

Table 4.18: Mean Biometric Data of Shellfishes in Agboyi Creekduring the Wet

Season...... 99

Table 4.19: Mean Biometric Data of Shellfishes in Lagos Lagoonduring the Dry

Season...... 100

Table 4.20: Mean Biometric Data of Shellfishes in Lagos Lagoonduring the Wet

Season...... 100

Table 4.21: Recoveries, Method Detection Limits (MDLs) and the Relative

Standard Deviation (RSD), Limits of Detection (LOD) and Limits

of Quantification (LOQ) of OCPs in Water Samples...... 101

Table 4.22: Recoveries, Method Detection Limits (MDLs) and the Relative

Standard Deviation (RSD) of OCPs in Sediment Samples...... 102

Table 4.23: Recoveries, Method Detection Limits (MDLs) and the Relative

Standard Deviation (RSD) of OCPs in Fish Samples...... 103

Table 4.24: Mean Concentrations (ng/mL) of Organochlorine Pesticide Residues

inMicrolayer and Mixed Layer Water during the Dry Season...... 104

Table 4.25: Mean Concentrations (ng/mL) of Organochlorine Pesticide Residues

in Microlayer and Mixed Layer Water during the Wet Season...... 105

Table 4.26: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in Epipellic and Benthic Sediments during the Dry Season...... 106

Table 4.27: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in Epipellic and Benthic Sediments during the Wet Season...... 107

Table 4.28: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inthe Muscle Tissues of Male and Female Tilapia guineensis

during the Dry and Wet Seasons...... 108

Table 4.29: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in the Muscle Tissues of Male and Female Tilapia

(Sarothorodon melanotheron) during the Dry and Wet Seasons...... 109

Table 4.30: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in the Muscle Tissues of Male and Female Bonga Fish

(Ethmalosa fimbriata) during the Dry and Wet Seasons in Lagos Lagoon.....110

Table 4.31: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in the Muscle Tissues of Male and Female Catfish

(Chrysichthys nigrodigitatus) during the Dry and Wet Seasons...... 111

Table 4.32: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in the Muscle Tissues of Male and Female Mullet

(Lizagrandisquamis) during the Dry and Wet Seasons...... 112

Table 4.33: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in the Muscle Tissues of Male and Female African Moony

(Psettias sebae)during the Dry and Wet Seasons in Lagos Lagoon...... 113

Table 4.34: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues in the Muscle Tissues of Male and Female Grouper

(Epinephelus aeneus) during the Dry and Wet Seasons in Lagos Lagoon.....114

Table 4.35: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues in the Muscle Tissues of Male and Female Barracuda

(Sphyraena guachancho) during the Dry and Wet Seasons...... 115

Table 4.36: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues in the Muscle Tissues of Male and Female Croaker

(Pseudotolithus senegalensis) during the Dry and Wet Seasons

in Lagos Lagoon...... 116

Table 4.37: Mean Concentrations (ng/g) of Organochlorine pesticide

Residues in the Muscle Tissues of Male and Female Croaker

(Pseudotolithus typus) during the Dry and Wet Seasons in

Lagos Lagoon...... 117

Table 4.38: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues in the Muscle Tissues of Male and Female Tongue Sole

(Cynoglossus canariensis) during the Dry and Wet Seasons in

Lagos Lagoon...... 118

Table 4.39: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues in the Muscle Tissues of Male and Female Snapper

(Lutjanus goreensis) during the Dry and Wet Seasons in

Lagos Lagoon...... 119

Table 4.40: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues in the Muscle Tissues of Male and Female Herring

(Sardinella maderensis) during the Dry and Wet Seasons in

Lagos Lagoon...... 120

Table 4.41: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues in the Muscle Tissues of Male and Female Jack Fish

(Caranx hippos) during the Dry and Wet Seasons...... 121

Table 4.42: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues in the Muscle Tissues of Male and Female Oarfish

(Regalecus glesne) during the Dry and Wet Seasons in Lagos Lagoon...... 122

Table 4.43: Mean Concentrations (ng/g) of Organochlorine Pesticide

Residues inthe Gills of Male and Female Tilapia guineensis

during the Dry and Wet Seasons...... 123

Table 4.44: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of Male and Female Tilapia (Sarothorodon melanotheron)

during the Dry and Wet Seasons in Agboyi Creek...... 124

Table 4.45: Mean concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of Male and Female Tilapia (Sarothorodon melanotheron)

during the Dry Season in Lagos Lagoon...... 125

Table 4.46: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of Male and Female Tilapia (Sarothorodon melanotheron)

during the Wet Season in Lagos Lagoon...... 126

Table 4.47: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in the Organs of Male and Female Bonga fish (Ethmalosa fimbriata)

during the Dry and Wet Seasons in Lagos Lagoon...... 127

Table 4.48: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of Male and Female Catfish (Chrysichthys nigrodigitatus)

during the Dry Season in Agboyi Creek...... 128

Table 4.49: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of male and female Catfish (Chrysichthys nigrodigitatus)

during the wet season in Agboyi Creek...... 129

Table 4.50: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of Male and Female Catfish (Chrysichthys nigrodigitatus)

during the Dry Season in Lagos Lagoon...... 130

Table 4.51: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of Male and Female Catfish (Chrysichthys nigrodigitatus)

during the Wet Season in Lagos Lagoon...... 131

Table 4.52: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in Gills of Male and Female Mullet (Lizagrandisquamis) during

the Dry and Wet Seasons in Agboyi Creek...... 132

Table 4.53: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of Male and Female Mullet (Lizagrandisquamis) during

the Dry Season in Lagos Lagoon...... 133

Table 4.54: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inOrgans of Male and Female Mullet (Lizagrandisquamis) during

the Wet Season in Lagos Lagoon...... 134

Table 4.55: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

in the Gills of Male and Female African Moony (Psettias sebae)

duringthe Dry and Wet Seasons in Lagos Lagoon...... 135

Table 4.56: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inMuscle Tissues of Male and Female Crab (Ocypoda africanus)

during the Dry and Wet seasons...... 136

Table 4.57: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inMuscle Tissues of Male and Female Shrimp (Penaeus notialis)

during the Dry and Wet Seasons...... 137

Table 4.58: Mean Concentrations (ng/g) of Organochlorine Pesticide Residues

inMuscle Tissues of Male and Female Crayfish (Procambarus clarkii)

during the Dry and Wet Seasons...... 138

Table 4.59: Bioconcentration Factor at Agboyi Creek………………………………….139

Table 4.60: Bioconcentration Factor at Lagos Lagoon………………………………….139

Table 4.61: Biota-Sediment Accumulation Factor at Agboyi Creek……………………140

Table 4.62: Biota-Sediment Accumulation Factor at Lagos Lagoon……………………140

Table 4.63: Estimated Daily Intakes (EDI) of OCP Residues

(ng/kg Body Weight/Day) by Humans……………………………………...141

Table 4.64: Acceptable Daily Intake(µg/kg Body Weight/Day) of

OrganochlorinePesticide Residues in Fish...... 142

LIST OF FIGURES

Figure 2.1: Schematic Diagram of a Typical Gas Chromatograph……………...... 57

Figure 3.1: Map of Lagos Lagoon and Surrounding Areas Showing

the Sampling Points...... 76

LIST OF PLATES

Plate 1: Agboyi Creek Terminus…………………………………………………...... 172

Plate 2: Investigator Williams Identifying Sampling Locations with

Garmin-GPSMAP 76S...... 172

Plate 3: Shellfishes Sampled for Organochlorine Pesticide Analysis…………………....173

Plate 4: Crab (Ocypoda africanus) Sampled for Organochlorine Pesticide

Analysis...... 173

Plate 5: Shrimp (Penaeus notialis) Sampled for Organochlorine Pesticide

Analysis...... 174

Plate 6: Crayfish (Procambarus clarkii) Sampled for Organochlorine Pesticide

Analysis...... 174

Plate 7: Tilapia (Tilapia guineensis) Sampled for Organochlorine Pesticide

Analysis...... 175

Plate 8: Mullet (Lizagrandisquamis) Sampled for Organochlorine Pesticide

Analysis...... 175

Plate 9: Catfish (Chrysichthys nigrodigitatus) Sampled for Organochlorine

Pesticide Analysis...... 176

Plate 10: African Moony (Psettias sebae) Sampled for Organochlorine Pesticide

Analysis...... 176

Plate 11: Bonga Fish (Ethmalosa fimbriata) Sampled for Organochlorine

Pesticide Analysis...... 177

Plate 12: Grouper (Epinephelus aeneus) Sampled for Organochlorine Pesticide

Analysis...... 177

Plate 13: Barracuda (Sphyraena guachancho) Sampled for Organochlorine

Pesticide Analysis...... 178

Plate 14: Croaker (Pseudotolithus senegalensis) Sampled for Organochlorine

Pesticide Analysis...... 178

Plate 15: Croaker (Pseudotolithus typus) Sampled for Organochlorine Pesticide

Analysis...... 179

Plate 16: Tongue Sole (Cynoglossus canariensis) Sampled for Organochlorine

Pesticide Analysis...... 179

Plate 17: Snapper (Lutjanus goreensis) Sampled for Organochlorine

Pesticide Analysis...... 180

Plate 18: Herring (Sardinella maderensis) Sampled for Organochlorine

PesticideAnalysis...... 180

Plate 19: Jack Fish (Caranx hippos) Sampled for Organochlorine Pesticide

Analysis...... 181

Plate 20: Oarfish(Regalecus glesne) Sampled for Organochlorine Pesticide

Analysis...... 181

LIST OF ACRONYMS AND ABBREVIATIONS

ADI Acceptable Daily Intake

AGR Agboyi Creek

ATSDR Agency for Toxic Substances and Disease Registry

BCF Bioconcentration Factor

BHC Benzene Hexachloride

BSAF Biota-Sediment Accumulation Factor

CF Condition Factor

CL Carapace Length

DDD Dichlorodiphenyldichloroethane

DDE Dichlorodiphenylethane

DDT Dichlorodiphenyltrichloroethane

EDI Estimated Daily Intake

EICD Electrolytic Conductivity Detector

EPA Environmental Protection Agency

FAO Food and Agriculture Organisation

FDC Fish Daily Consumption

FEPA Federal Environmental Protection Agency