Dr.DHAVALE PRAMOD C
From:
Dr.DHAVALE PRAMOD C.
Post Graduate Student,
Post Graduate Dept. of Materia Medica,
DBHP Sabha’s. DR. B.D. Jatti Homoeopathic Medical College,
Hospital & P.G. Research Centre,
D.C. Compound, Dharwad – 580001.
To:
The Registrar
Rajiv Gandhi University of Health Sciences, Karnataka,
Bangalore.
Through:
The Principal
DBHP Sabha’s. DR. B.D. Jatti Homoeopathic Medical College,
Hospital & P.G. Research Centre,
Dharwad-580001.
Respected Sir,
Subject: Submission of Completed Proforma for Registration of
Subject for Dissertation.
I request you to kindly register the below mentioned subject against my name for the submission of dissertation to the Rajiv Gandhi University of Health Sciences, Bangalore for partial fulfillment of M.D.(Homoeopathy).
Title of Dissertation:
“A CLINICAL STUDY OF THUJA OCCIDENTALIS IN THE MANAGEMENT OF WARTS”
I am herewith enclosing completed Proforma for registration of subject for dissertation.
Thanking you,
Yours faithfully,
PLACE: Dharwad.
DATE:
(Dr.DHAVALE PRAMOD C.)
“A CLINICAL STUDY OF THUJA OCCIDENTALIS IN THE MANAGEMENT OF WARTS”
SYNOPSIS
Submitted to
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES
KARNATAKA, BANGALORE.
BY
Dr. DHAVALE PRAMOD C.
Through
DBHPS’S
DR. B.D. JATTI HOMOEOPATHIC MEDICAL COLLEGE, HOSPITAL & P.G. RESEARCH CENTRE, D.C. COMPOUND, DHARWAD – 580001 (KARNATAKA).
In partial fulfillment of requirement for the
DOCTOR OF MEDICINE (HOMOEOPATHY)
HOMOEOPATHIC MATERIA MEDICA
Under the valuable guidance of
Dr. M. SUNIL KUMAR TAMPI, M.D. (Hom)
Reader and Guide
Dept. of Materia Medica.
DR. B.D. JATTI HOMOEOPATHIC MEDICAL COLLEGE, HOSPITAL & P.G. RESEARCH CENTRE, D.C. COMPOUND, DHARWAD – 580001 (KARNATAKA).
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, KARNATAKA,
BANGALORE.
Annexure-II
REGISTRATION OF SUBJECT FOR DISSERTATION
1. / NAME OF CANDIDATE & ADDRESS / Dr. DHAVALE PRAMOD C.Post Graduate Student,
Post. Graduate Dept. of Materia Medica,
DR. B. D. Jatti Homoeopathic Medical College, Hospital and P.G. Research Centre,
Dharwad- 580001.
PERMANENT ADDRESS / Dr. DHAVALE PRAMOD C.
#47/1/1, Rahul nagar, Kurla mahul Road
Vashi naka, Chembur, Mumbai- 400074
Maharashtra.
2. / NAME OF THE
INSTITUTION. / D.B.H.P.Sabha’s
DR. B. D. Jatti Homoeopathic Medical College, Hospital and P.G. Research Centre,
D.C. Compound,
Dharwad- 580001.
3. / COURSE OF STUDY AND SUBJECT. / M.D. (HOM) – (Doctor of Medicine in Homoeopathy)
HOMOEOPATHIC MATERIA MEDICA
4. / DATE OF ADMISSION TO COURSE. / 25-04-2009.
5. / TITLE OF THE TOPIC. / “ A CLINICAL STUDY OF THUJA OCCIDENTALIS IN THE MANAGEMENT
OF WARTS.”
6. / BRIEF RESUME OF THE INTENDED WORK
6.1 / Need for the study:
Verrucae or warts are common lesion of skin in children and adolescent although they may be encountered at any age.
Transmission usually involve direct contact between individual or
autoinoculation.
Warts makes disfiguring of face or neck and warts on the fingers interfere in fine movement.
Warts are hyperkeratotic skin out growth of mainly sycotic manifestation due to internal derangement of vital force. Destruction of their infected area of epidermis by using external application, or by surgery is not the only solution for this problem, as it is the external manifestation of internal deranged vital force these should be treated by dynamic remedies.
Homoeopathy is said to effective in the management of skin disorder like warts and etc which consider the patient as whole, on the basis of totality of symptom and individualization. These not only remove the warts but also restore the internal deranged vital force. And also prevent recurrence.
Hence a systematic study of clinical presentation of warts and the effect of Thuja Occidentalis in the management of warts.
6.2 / REVIEW OF LITERATURE:
1. Verrucae or warts are common viral lesion of skin. They are caused by human papilloma virus (HPV) that belongs to papovavirus group, a type of DNA oncogenic virus1.
2. Papilloma viruses are species specific uninfect squamous epithelia and mucous membrane, inducing different types of warts or papillomata in their host. Human papilloma virus (HPV) infects only humans and grows only in organ culture of human skin2.
3. Common warts (varrucae vulgaris) usually found on hand and feet of children and adolescent are mostly cause by types 1, 2, 3 and 42.
4. Papilloma virus are small 52-55 nm diameter DNA virus. All the PV’s are highly host and species specific. HPV only infects humans3.
5. Warts occur at any age and in both sexes, and incidence of 10% has been estimated for children and young adult. It is low in early child hood and reaches peak between 12 and 16 years of age. Then decline sharply to the age of 20 or more. Impairment of cell mediated immunity increases the susceptibility to HPV infection3.
6. Histological features common to verrucae includes epidermal hyperplasia that is often undulant in character and cytoplasmic vacuolization (Koilocytosis) that preferentially involves the more superficial epidermal layer, producing halos of pallor surrounding infected nuclei4.
7. Three types of warts may be seen:
a) Common warts.
b) Senile warts.
c) Venereal warts or papilloma accuminata5.
8. Plantar warts are endophytic and are covered by thick keratin. Pairing of warts will generally demonstrate a central core of keratinzed debris and punctuate bleeding point6.
9. Warts are situated on back, cervical region, upper limb, face, nose, eyebrows, eyes and eyelids, external throat. They are broad, conical, flat pedunculated, indented, fan shaped in appearance. They are reddish in colour, bleed easily. The warts have a tendency to split from their edge or from the surface7.
10. Skin: looks dirty; brown or brownish-white spots here and there; warts, large, seedy, pedunculated (staph.); eruption only on covered parts, burn after scratching8.
11. Thuja has the formation of wart –like growths upon mucous and skin surfaces, fig-warts and condylomata9.
12. Warts like excerscences on back of right hand, on chin, and other places; on hands, in shape of a truncated cone, smooth, in epidermis, later the largest were rough and split, the larger ones become depressed in centre. Warts on hand; on backs of hands and fingers, the old horny ones were painful on touch and washing, with red areola, afterwards10.
13. The only efficacious remedy for fig-warts and gonorrhoea. He used the 30th potency, and the found that in the 60th potency, “it had not sunk to complete powerlessness, but on the contrary had rather become even more intensely charged with the medicinal virtue of Thuja”11.
14. Skin, fig-warts; condylomata; tubercles; sycosis.
Thuja was Hahnemann’s great remedy for sycosis, that peculiar poison whose characteristic action is shown upon the skin and mucous membrane by the formation of fig-warts and condylomata12.
15. Sycosis (condylomatous disease), equally ineradicable by the vital force without proper medicinal treatment, was not recognised as a chronic miasmatic disease of peculiar character, with it nevertheless undoubtedly is, and physicians imagined they had cured it when they had destroyed the growths upon the skin, but persisting dyscrasias occasioned by it escaped their observation13.
16. The sycotic patient may subject to warts, verucas, moles, condylomatas, skin tags, dermoid cyst, fibromas and lipomas. Genital warts may appear in both sexes14.
17. Thuja- the main action of thuja is on skin and genitourinary organ, producing conditions that correspond with Hahnemann sycotic dyscrasias, whose chief manifestation is the formation of wart excrescences upon mucous and cutaneous surface- fig- warts and condylomata15.
6.3 / AIMS AND OBJECTIVES OF THE STUDY:
1. To study the effect of Thuja Occidentalis in warts.
2. To study the clinical presentation of warts.
3. To study the homoeopathic management of warts.
7. / MATERIALS AND METHODS:
7.1 / PRIMARY SOURCE:
The subject for this study will be collected from OPD/IPD/Rural camp of DR.B.D. Jatti Homoeopathic Medical College, Hospital and Post Graduate Research Centre, Dharwad.
7.2 / METHOD OF COLLECTION OF DATA (Including sampling procedure, if any)
Definition of study subject:
Patients are considered on the basis of clinical presentations, like hyperkeratotic growth on skin and positive punch biopsy for human papilloma.
Following are inclusion criteria:
1. Patient of all the age group and sex.
2. Patient irrespective of ethnic group socioeconomic status and occupation will be considered.
Following are exclusion criteria:
1. Patient with any other chronic disease on active treatment.
2. Genital warts.
Study sampling design:
Prevalence rate of warts in our hospital is 2% considering the 95% confidence interval at 5% permissible error, sample size works out to be 32 cases, Since it is a time bound study, all admitted and OPD cases are included in my study period.
Follow up :
Cases are followed for a period of 5-6 month during the course of study. Examination is done periodically.
Parameters used are :
a) Clinical examination.
b) Disappearance of warts.
c) Reduction in size.
Study period:
From 30th November 2009 to 30th November 2011.
Statistical tests:
Appropriate test will be used depending upon the data available at the end of the study.
7.3
7.4 / DOES THE STUDY REQUIRE ANY INVESTIGATIONS OR INTERVENTIONS TO BE CONDUCTED ON PATIENTS OR OTHER HUMAN OR ANIMALS? IF SO DESCRIBE BRIEFLY.
The study requires following investigations to be conducted on patients.
- Blood: Hb%, TC, DC, ESR if required.
- Urine routine: physical, chemical
- Punch biopsy: if required.
Yes, Ethical clearance has been obtained from the institution.
8. / LIST OF REFERENCE:
1. Mohan Harsh: Text Book of Pathology, 5th edition, Jaypee Brother’s Medical publisher (P) ltd. New Delhi, 2005, p 797.
2. Panikar C.K Jayaram: Ananthnarayan and Panikers Text book of Microbiology, 7th edition, Orient Longman (p) ltd, Hyderabad, 2005, p 562.
3. Shah Siddharth N.: API textbook of Medicine, 8th edition, The association of Physician of India, 2008, p 98.
4. Mitchell, Nelson Fausto, Abbas, Kumar: Robbins basic Pathology, 8th edition, SUNDERS ELSEVIER, 2007, p 844.
5. Das Somen: A concise Textbook of surgery, fourth edition, published by Dr. S. DAS, Calcutta, Feb 2006, p 112.
6. Harrison’s 15th edition, Principle of internal medicine, Vol1, McGraw Hill Medical publishing division, 2001, p 314.
7. Master Farokh J.: Disease of the Skin including the Exanthemata, B.Jain publishers. Pvt ltd, New Delhi, 1998, p 140,141.
8. Allen H.C: Keynotes Rearranged and Classified with Leading Remedies of the Materia Medica and Bowel Nosodes, 9th edition, B.jain publishers (p) ltd, 2002, p 333.
9. Murphy Robin: Lotus Materia Medica 2nd Revised edition.B.Jain Publishers, New Delhi, p 1768.
10. Allen T.F: Handbook of Materia Medica and Homoeopathic Therapeutics, Indian Books and periodicals publishers, New Delhi, p 1122.
11. Tayler M.L: Homoeopathic Drug Pictures, reprint edition 1998, B.Jain publishers, New Delhi, p 819.
12. Burt W.H: Physiological Materia Medica, 3rd edition, B.jain publishers, New Delhi, reprint edition 2008, p 925.
13. Sarkar B.K: Organon of Medicine By Samuel Hahnemann, 9th edition, Birla Publication, Delhi, p 164-165.
14. Banerjea Subrata K.: Miasmatic prescribing: Miasmatic diagnostic classification of skin symptoms taken from Website: www. Homoeopathy-course.com.
15. Boericke William: Pocket Manual Of Homoeopathic Materia Medica and Repertory, reprint edition 2003, B.jain publishers, New Delhi, p 643.
9. / Signature of the candidate
10. / Remarks of the guide
11. / 11.1 / Name and Designation of (IN BLOCK LETTER) Guide / Dr.M. SUNIL KUMAR TAMPI, M.D(Hom)
Reader and Guide,
Post Graduate Dept. of Homoeopathic Materia Medica,
DR. B.D. Jatti Homoeopathic Medical College, Hospital and Post Graduate Research Centre, Dharwad-01.
11.2 / Signature
11.3 / Co-guide
11.4 / Signature
11.5 / Head of the Department. / Dr.R.Y.NADAF,
M.D(Hom)
Principal and H.O.D,
Post Graduate Dept. of Homoeopathic Materia Medica ,
DR. B.D. Jatti Homoeopathic Medical College, Hospital and Post Graduate Research Centre, Dharwad-01.
11.6 / Signature
12. / 12.1 / Remarks of Principal
12.2 / Signature.