Dr.A.Venkat Narsaiah,Senior Scientist,Research Highlights:
I. Total number of publications: 96
II. Total number of citations: 2000 (incomplete)
III. Average citations: 22 (ISI Web of Science)
IV. H-index: 25 (ISI Web of Science)
Research experience:
Synthesis of drugs and drug intermediates, target oriented synthesis (antimicrobial) of natural and un-natural molecules.
Project investigator in Open Source Drug Discovery (OSDD) program to develop Ethambutol based new molecules for Tuberculosis.
Project investigator in Organic Reactions in Generating New Scaffolds (ORIGIN) and
Project investigator in Development of Novel Vaccine Adjuvant.
Synthesis of new chemical entities using Glycerine as alternative solvents.
List of publications experience:
96. Scalable Synthesis of anti-depression agent Agomelatine.
J. Kranthi Kumar, L. Radhika, A. Venkat Narsaiah.
Organic Preparations Procedures International.2015(accepted).
95. Stereoselective total synthesis of Pectinolides A, C and H.
RS. Ghogare, SB. Wadavrao, A.Venkat Narsaiah.
Helvetica Chimica Acta. 2015 (accepted).
94. Synthesis and characterization of 1,4-di hydropyridines catalyzed by Zn(OTf)2.
DS.Latha,GSSNReddy,YVLu,LN.Sharada,YV.Lu, B. Nagaiah,
A. Venkat Narsaiah.
American Journal of PharmTech Research.2015,5, 439.
93. An efficient Enantioselective Synthesis of Natural Gingerols, the active
principles of Ginger.
A.Ramesh Reddy, SB. Wadavrao, JS. Yadav, A. Venkat Narsaiah.
Helvetica Chimica Acta. 2015, 98, 1009.
92. Development and Validation RP-HPLC Method for Estimation of Cinacalcet
in Bulk and Tablet Dosage Form.
NS.Ganesh, M.Ratanlal,A. Venkat Narsaiah, KVLD. Spandana, N. Sagar,
T. Sridhar
American Journal of PharmTech Research.2015, 5, 454.
91. A Concise Total Synthesis of (+)-18-(6S,9R,10R)-Bovidic Acid.
SB. Wadavrao, RS. Ghogare, A. Venkat Narsaiah.
Helvetica Chimica Acta. 2015, 98,575.
90. Total synthesis of Nonenolide-Xyolide using regioselective nucleophilic
epoxide opening approach.
SB. Wadavrao, RS. Ghogare, A. Venkat Narsaiah.
Synthesis.2015, 47,2129.
89. Glycerol Mediated Strecker Reaction: Catalyst-free Protocol for the Synthesis
of α-Amino Nitriles.
RS. Ghogare, K. Rajeshwari, A. Venkat Narsaiah.
Letters in Organic Chemistry. 2014,11, 688.
88. Stereoselective synthesis of tuberculostatic agent (S,S)-Ethambutol.
J. Kranthi Kumar, A. Venkat Narsaiah.
Organic Communications. 2014,7, 28.
87. A simple and efficient synthesis of Cinepazide.
B. Nagaiah, A. Venkat Narsaiah.
Synthetic Communications. 2014, 44, 1227.
86. Concise synthesis of a novel anti- fungal agent 4-methoxydecanoic acid.
P. Narsimha, A. Venkat Narsaiah.
Organic Communications. 2013, 6, 134.
85. A noninfringing route for enantio selective synthesis of antiepileptic
agent Lacosamide.
SB. Wadavrao, N. Ashritha, A. Venkat Narsaiah.
Synthesis. 2013,3383.
84. Enantioselective synthesis of the natural product (S)-Rugulactone.
B. Nagaiah, A. Venkat Narsaiah.
Helvetica Chimica Acta. 2013, 96, 1948.
83. Enantioselective construction of 6-substituted-α,β-unsaturated-δ-Lactone:
Total synthesis of antibacterial agent (-)-Cleistenolide.
RS. Ghogare, SB. Wadavrao, A. Venkat Narsaiah.
Tetrahedron Letters. 2013,54, 5674.
82. A simple and efficient protocol for the synthesis of Quinoxalines catalyzed
by pyridine.
SB. Wadavrao, RS. Ghogare, A. Venkat Narsaiah.
Organic Communications. 2013, 6, 23.
81. A concise enantioselective synthesis of a β1-adrenoceptor antagonist
(S)- Bevantolol.
M. Narsimha, B.Haritha, A. Venkat Narsaiah.
Organic Synthesis and Medicinal Chemistry. 2012, 1-4.
80. A simple and efficient method for three-component coupling of aldehyde,
amine and alkyne via C-H activation.
P. Narsimha, A. Venkat Narsaiah.
ChemXPress. 2012,23.
79. Stereoselective synthesis of a marine natural product Oxylipin-3.
SB. Wadavrao, RS. Ghogare, A. Venkat Narsaiah.
Tetrahedron Letters. 2012, 53, 3955.
78. CNS-Agent precursor: a simple and efficient synthesis of an antipsychotic
drug Fluanisone.
A. Venkat Narsaiah,B. Nagaiah, B. Karuna Devi.
Journal of Heterocyclic Chemistry. 2012,49, 829.
77. Efficient synthesis of antihistamines Clocinizine and Chlorcyclizine.
A. Venkat Narsaiah, P. Narsimha.
Medicinal Chemistry Research. 2012,21,538.
76. Glycerine-CeCl3.7H2O: a new and efficient recyclable reaction medium for
the synthesis of Quinoxalines.
A. Venkat Narsaiah, J. Kranthi Kumar.
Synthetic Communications.2012,42, 883.
75. An expedient stereoselective synthesis of antifungal agent (6S)-5,6-dihydro-
6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one.
A. Venkat Narsaiah,RS. Ghogare
Synthesis.2011,3271.
74. Glycerine as alternative solvent for the synthesis of 2,4-disubstituted Thiazoles.
A. Venkat Narsaiah, RS. Ghogare, DO.Biradar
Organic Communications. 2011, 3, 75.
73. A simple and efficient synthesis of Calcium channel blocker Flunarizine.
A. Venkat Narsaiah,J. Kranthi Kumar.
International Journal of Industrial Chemistry. 2011,3, 154.
72. Sm (OTf)3 catalyzed Biginelli condensation: an improved method for synthesis
of 3,4-dihydropyrimidin-2(1H)-ones.
A. Venkat Narsaiah, AR. Reddy, JS. Yadav.
Synthetic Communications.2011,41, 2794.
71. A novel asymmetric synthesis of (S)-Esmolol using hydrolytic kinetic Resolution.
A. Venkat Narsaiah, J. Kranthi Kumar.
Synthetic Communications.2011, 41, 1603.
70. Amberlyst-15: an efficient, cost-effective and recyclable heterogeneous solid
acid catalyst for the synthesis of β-enaminones and β-enaminoesters.
A. Venkat Narsaiah, AR. Reddy, BVS. Reddy, JS. Yadav.
Open Catalysis Journal. 2011, 4, 43.
69. Glycerine-CeCl3: an efficient and recyclable reaction medium for ring opening
of epoxides with thioamides and amines.
A. Venkat Narsaiah, SB. Wadavrao, AR. Reddy, JS. Yadav.
Synthesis.2011,485.
68. A mild and highly efficient protocol for the synthesis of benzimidazoles
using Sm(OTf)3.
A. Venkat Narsaiah, AR. Reddy, JS. Yadav.
Synthetic Communications.2011,41,262.
67.Copper (II) acetyl acetonate: an efficient catalyst for one-pot synthesis of
3,4-dihydropyrimidin-2-(1H)-ones.
J. Anil Kumar, A. Venkat Narsaiah.
International Journal of Applied Biology & Pharm. Technology.2010, 3,935.
66. A simple and efficient enantioselective synthesis of (S)-Esmolol.
A. Venkat Narsaiah, J. Kranthi Kumar.
International Journal of Industrial Chemistry. 2010, 1, 1-4
65. A simple and straightforward synthesis of antihistaminic drug Cetirizine
A. Venkat Narasaiah, P. Narsimha, G.Navitha.
International Journal of Applied Biology &Pharm. Technology. 2010, 736.
64. Glycerine-CeCl3.7H2O: an efficient recyclable reaction medium for the synthesis
of Hantzsch pyridines.
A. Venkat Narsaiah,B. Nagaiah
Asian Journal of Chemistry.2010, 22, 8099.
63. A simple and efficient asymmetric synthesis of anxiolytic drug Enciprazine.
A. Venkat Narsaiah,B. Nagaiah.
Synthesis. 2010, 2705.
62. Sm(OTf)3 as mild and efficient catalyst for aza-Diels-Alder reaction:
a facile synthesis of cis-fused pyrano and furano quinolines.
A. Venkat Narsaiah, AR.Reddy, BVS.Reddy, JS. Yadav
Synthetic Communications.2010,40, 12, 1750
61. A simple and efficient synthesis of anti-migraine drug Lomerizine.
A. Venkat Narsaiah, J. Kranthi Kumar.
Synthesis. 2010, 1989.
60. A simple and efficient method for three component synthesis of homo
allylic amines catalyzed by In(OTf)3.
A. Venkat Narsaiah, J. Kranthi Kumar, P. Narsimha.
Synthesis. 2010, 1609.
59. Bismuth-catalyzed hydrolysis of epoxides & aziridines: an efficient synthesis of
vic-diols and-amino alcohols.
A. Venkat Narsaiah, BVS.Reddy,K. Premalatha, SS. Reddy, JS. Yadav
Catalysis Letters. 2009, 131, 480.
58. Total synthesis of Xestodecalactone-C from L-Malic acid.
JS.Yadav, YG. Rao, K. Ravindar, BVS.Reddy, A. Venkat Narsaiah.
Synthesis.2009,3157.
57. Mg-CdCl2:a bimetallic catalytic system for allylation of aldehydes with
allylbromide: an efficient protocol for synthesis of homoallylic alcohols.
A. Venkat Narsaiah, AR.Reddy, YG.Rao, EV.Kumar, RS.Prakasham,
BVS.Reddy, JS. Yadav.
Synthesis. 2008, 3461.
56. Bi(OTf)3 as mild, efficient and cost-effective catalyst for the alkylation of
N-heterocycles with epoxides.
JS.Yadav, BVS.Reddy,AD.Krishna, AR.Reddy,A. Venkat Narsaiah.
Letters in Organic Chemistry. 2008, 5, 455.
55. First example of Cu(OTf)2 catalyzed synthesis of 2-amino thiozoles from α-diazo
ketones and thiourea.
JS. Yadav, BVS. Reddy, YG. Rao, A. Venkat Narsaiah.
Tetrahedron Lett. 2008,49, 2381.
54. PMA/SiO2 as mild, efficient and cost-effective heterogeneous catalyst for
Chemoselective protection of amines with (Boc)2O.
JS. Yadav, BVS. Reddy, YG. Rao, AR. Reddy, A. Venkata Narasaiah.
Letters in Organic Chemistry. 2008, 5, 116.
53. First example of Cu(OTf)2 catalyzed synthesis of quinoxalines from α-diazo
ketones and aryl-1,2-diamines.
JS. Yadav, BVS. Reddy, YG. Rao, A. Venkat Narsaiah.
Chemistry Letters. 2008, 3, 348.
52. Microwave promoted alkylation of Halonitrobenzenes with malonates in
Solvent-free conditions.
A. Venkat Narsaiah
Catalysis Letters. 2008,121, 81.
51. A chemoselective and efficient hetero atom nucleophilic addition to
Electron deficientolefins catalyzed by Sm(OTf)3(aza-Michael reaction).
JS. Yadav, AR. Reddy, YG. Rao, A.Venkat Narsaiah, BVS. Reddy.
Synthesis.2007,22,3447.
50. LaCl3 Accelerated conjugate addition of amines to electron poor alkenes.
A. Venkat Narsaiah.
Letters in Organic Chemistry. 2007, 4, 462.
49. Cu(OTf)2: Catalyzed synthesis of imidazo-[1,2-a]-pyridines from α-diazo
ketonesand 2-amino pyridines.
JS.Yadav, BVS. Reddy, YG. Rao, M.Srinivas, A. Venkat Narsaiah.
Tetrahedron Letters. 2007, 48, 7717.
48. Iodine as a mild, efficient and cost-effective reagent for the synthesis of cis-1-
oxo-1,2,3,4-tetrahydroisoquinolone-4-carboxylic acids.
JS.Yadav, BVS. Reddy, AR. Reddy, A. Venkat Narsaiah.
Synthesis.2007,20, 3191.
47. LaCl3: an efficient catalyst for the silylation of hydroxyl groups by activating
HMDS.
A. Venakt Narsaiah.
Journal of Organometalic. Chemistry. 2007,692, 3614.
46. Microwave accelerated SN2' substitution of Baylis-Hillman acetates: a
Comparative study of conventional heating vs MW-irradiation.
JS. Yadav, BVS.Reddy, AK. Basak, A. Venkat Narsaiah.
Journal of Molecular and Catalysis. A. 2007, 274, 105
45. GaCl3: Catalyzed addition of thiols to glycols: a facile synthesis of 2-deoxythio-
glycosides.
JS. Yadav, BVS. Reddy, EV.Bhaskar,S.Raghavender, A. Venkat Narsaiah.
Tetrahedron Lett. 2007, 48, 677.
44. An efficient protocol for regioselective ring opening of epoxides using Sm(OTf)3:
Synthesis of Propranolol, Atenolol and RO-363.
JS.Yadav, AR. Reddy, A. VenkatNarsaiah,BVS. Reddy.
Journal of Molecular and Catalysis. A. 2007, 261,207.
43. TPP: An efficient catalyst for transesterification of -ketoesters.
JS.Yadav, BVS.Reddy, AD.Krishna, CS.Reddy, A. Venkat Narsaiah.
Journal of Molecular and Catalysis. A. 2007, 261, 93.
42. An efficient protocol for reductive amination of aldehydes & ketones with NaBH4-
ionic liquid/H2O system.
K.Nagaiah,VN. Kumar, RS.Rao, BVS.Reddy, JS.Yadav, A.Venkat Narsaiah.
Synthetic Communications. 2006, 36, 3345-3352.
41. InBr3: An efficient catalyst for the silylation of hydroxyl groups by activating
HMDS.
JS. Yadav, BVS. Reddy, AK.Basak, G.Baishya, A. Venkat Narsaiah.
Synthesis. 2006, 22, 3831.
40. An efficient synthesis of -amino alcohols catalyzed by NbCl5: Region selective
Ring opening of epoxides with aromatic amines.
A. Venkat Narsaiah, D. Sreenu,K. Nagaiah.
Synthetic Communications.2006, 36, 3183.
39. LiClO4-catalyzed cleavage of aziridines with thiols: a facile synthesis of -amino
Sulphides.
JS.Yadav, BVS.Reddy, G.Baishya, PVR.Reddy, A. Venkat Narsaiah.
Catalysis Communications. 2006, 10, 807.
38. Differentiation of isomeric substituted diaryl ethers by electron ionisation
and Chamical ionization.
G.Bhaskar, S.Prabhakar, A. Venkat Narsaiah, K.Nagaiah,GSR.Anjineyulu,
M.Vairamani.
European Journal of Mass Spectroscopy. 2006, 12, 161.
37. NbCl5: An efficient catalyst for the selective acetylation of amines and thiols
under mild reaction conditions.
JS. Yadav,D. Sreenu, A. VenkatNarsaiah, AK. Basak, PR. Goud, K. Nagaiah.
Journal of Molecular and Catalysis A. 2006, 255, 78.
36. Asymmetric synthesis of (2S)-1-(3,4-dihydroxyphenolxy)-ethyl amino-2-propanol
hydrochloride (RO363).
A. Venkat Narsaiah.
Synthetic Communications. 2006, 36, 1897.
35. IBX: An efficient and novel oxidizing agent for the aromatization of 1,4-dihydro
pyridines.
JS.Yadav,BVS.Reddy, AK.Basak,G.Baishya, A. Venkat Narsaiah.
Synthesis. 2006, 3, 451.
34.TPP-I2: An efficient reagent system for the synthesis of nitriles fromaldoximes.
A. Venkat Narsaiah, D.Sreenu, K.Nagaiah.
Synthetic Communications. 2006, 36, 137.
33. Conjugate addition of indoles to , -unsaturated ketones using Cu(OTf)2
immobilized in ionic liquids.
JS.Yadav, BVS.Reddy, G.Baishya,KV.Reddy, A. Venkat Narsaiah.
Tetrahedron.2005, 9541.
32.CBr4: An efficient catalyst for regio selective ring opening of epoxides
withalcohols and water.
JS.Yadav, BVS.Reddy, K. Harikishan, C.Madhan, A. Venkat Narsaiah.
Synthesis. 2005, 17, 2897.
31.A novel and efficient protocol for the tetrahydropyranylation of alcoholsand
Phenols catalyzed by NbCl5.
K. Nagaiah, BVS. Reddy, D. Sreenu, A. Venkat Narsaiah.
Arkivoc. 2005, 192.
30. FeCl3-Promoted electrophilic thio cyanation of aromatic and hetero
aromatic compounds.
JS.Yadav, BVS.Reddy, AD.Krishna,CS.Reddy, A. Venkat Narsaiah.
Synthesis. 2005, 6, 961.
29. NbCl5: An efficient catalyst for selective acetylation of alcohols and phenols.
JS. Yadav, A. Venkat Narsaiah, BVS.Reddy, AK.Basak, K.Nagaiah.
Journal of Molecular andCatalysis. A.2005,230, 107.
28. Cu(OTf)2 immobilized in [bmim] BF4 ionic liquid: an efficient reaction medium for
Michael addition of -keto esters to acceptor activated alkenes.
JS.Yadav, BVS. Reddy, G. Baishya, A. Venkat Narsaiah.
Chemistry Letters. 2005, 102.
27. First example of C-alkylation of indoles with Baylis-Hillman acetates.
JS.Yadav,BVS.Reddy, AK. Basak, A. Venkat Narsaiah, A.Prabhakar,
B.Jagadish.
Tetrahedron Letters.2005, 47, 639
26. An efficient asymmetric synthesis of (S)-Atenolol: Using hydrolytic kinetic
Resolution.
DS.Bose, A. Venkat Narsaiah.
Bioorganic and Medicinal Chemistry.2005, 13, 627.
25. An efficient and improved method for the preparation of nitriles from primary
amides and aldoximes.
A. Venkat Narsaiah, K.Nagaiah.
Advanced Synthesisand Catalysis. 2004, 346, 1271.
24. Acylative cleavage of aziridines with acid anhydrides catalyzed by Sc(OTf)3.
JS.Yadav, BVS.Reddy, K.Sadashiv,K. Harikishan, A. Venkat Narsaiah.
Journal ofMolecular and Catalysis.A. 2004, 220, 153.
23. An eco-friendly synthesis of diaryl ethers without catalyst under MW-Irradiation.
A. Venkat Narsaiah, K. Nagaiah.
Indian Journal of Chemistry B. 2004, 2478.
22. An eco-friendly synthesis of electrophilic alkenes catalyzed by DMAP under
Solventfree conditions.
A. Venkat Narsaiah, AK. Basak, B. Visali, K. Nagaiah.
Synthetic Communications. 2004, 34, 2893
21. Cadmium chloride: an efficient catalyst for one-pot synthesis of 3,4-dihydro
Pyridin (1H)-ones.
A. Venkat Narsaiah, AK. Basak, K. Nagaiah.
Synthesis.2004, 8, 1253.
20. TPP-Catalyzed Knoevenagel condensation: a facile synthesis of -cyano
acrylates and -cyano acrylic nitriles.
JS.Yadav, BVS.Reddy, AK. Basak, B.Visali,K. Nagaiah, A. Venkat Narsaiah.
European Journal of Organic Chemistry.2004, 546.
19. Baeyer-Villiger oxidation in ionic liquid: a facile conversion of ketones to
esters and lactones.
JS.Yadav, BVS. Reddy, AK Basak, A. Venkat Narsaiah.
Chemistry Letters. 2004, 248.
18. Efficient halogenation of aromatic systems using N-halo succinamides in
ionic liquid.
JS.Yadav, BVS.Reddy, PSR.Reddy, AK.Basak, A. Venkat Narsaiah.
Advanced Synthesis and Catalysis.2004, 346, 77.
17. Recyclable 2nd generation ionic liquids as green solvents for the oxidation
of alcohols with IBX.
JS. Yadav, BVS. Reddy, AK. Basak, A. Venkat Narsaiah.
Tetrahedron. 2004, 60, 2131-2135.
16. LaCl3: mediated regeneration of carbonyl compounds from oximes inWater.
A. Venkat Narsaiah, K. Nagaiah.
Indian Journal of Chemistry B.2003,2045.
15. An efficient Knoevenagel condensation catalyzed by LaCl3.7H2O in
Heterogeneous medium.
A. Venkat Narsaiah, K. Nagaiah.
Synthetic Communications. 2003, 33, 3825.
14. Three-component coupling reactions in ionic liquid: an improved protocol for the
synthesisof 1,4-dihydropyridines.
JS.Yadav, BVS.Reddy, AK.Basak, A. Venkat Narsaiah.
Green Chemistry.2003, 60.
13. [Bmim]PF6 and [Bmim]BF4 ionic liquid as novel and recyclable reaction media for
aromatic amination.
JS. Yadav, BVS. Reddy, AK. Basak, A. Venkat Narsaiah.
Tetrahedron Letters.2003,44, 2217.
12. [Bmim]BF4 ionic liquid: a novel reaction medium for the synthesis of -amino
alcohols.
JS. Yadav, BVS. Reddy, AK. Basak, A. Venkat Narsaiah.
Tetrahedron Letters. 2003, 44, 1047.
11. Aza-Michael reactions in ionic liquids: a facile synthesis of -amino compounds.
JS.Yadav, BVS. Reddy, AK. Basak, A. Venkat Narsaiah.
Chemistry Letters. 2003, 32, 988.
10. SbCl5: Promoted regeneration of carbonyl compounds from oximes.
A. Venkat Narsaiah,K.Nagaiah.
Synthesis.2003, 12, 1881.
9. Potassium monopersulfate triplesalt [Oxone]. Spotlight.
A. Venkat Narsaiah.
Synlett. 2002, 1178.
8. FeCl3: Induced catalytic cleavage of oximes and hydrazones under solvent free
conditions.
DS. Bose, A. Venkat Narsaiah, PR. Goud.
Indian Journal of Chemistry B. 2001,719.
7. An efficient benzyl triethyl ammonium chloride catalyzed preparation of
electrophilic alkenes. A practical synthesis of Trimethoprim.
DS. Bose, A. Venkat Narsaiah.
Journal of Chemical Research (S). 2001,36.
6. Use of PyBOP as a convenient activator for the synthesis of nitriles from primary
amides.
DS. Bose, A. Venkat Narsaiah.
Synthesis.2001, 373.
5. Regeneration of carbonyl compounds from oximes and hydrazones using oxone-
SiO2 under solvent free conditions.
DS. Bose, A. Venkat Narsaiah,V.L. Narayana.
Synthetic Communications. 2000, 30, 3121.
4. Quinolenium Fluoro Chromate (QFC: an efficient reagent for the cleavage of
C=Nof oximes andhydrazones.
DS. Bose, A. Venkat Narsaiah.
Synthetic Communications. 2000, 30, 1153.
3. Efficient method for selective cleavage of acetals and ketals using oxone-alumina
under solvent free conditions.
DS. Bose, B. Jayalakshmi, A. Venkat Narsaiah.
Synthesis. 2000, 67.
2. A facile method for the conversion of oximes and tosyl hydrazones to carbonyl
Compounds with DMP.
DS. Bose, A. Venkat Narsaiah.
Synthetic Communications. 1999, 29, 937.
1. Efficient one-pot synthesis of nitriles from aldehydes in solid state using oxone-
alumina.
D.S. Bose, A. Venkat Narsaiah.
Tetrahedron Letters. 1998, 39, 6533.
1