Suppl. Figure 2: Box Plots of Various Synaptic Parameters

Supplemental Material

Suppl. Figure 1: Box plots of various structural parameters show only slight differences between individual animals.

Data distributions as indicated by the medians (horizontal bars) and interquartile ranges (framed areas) and minimum and maximum (vertical lines) are shown for volume (A), surface area (B), surface vs. volume (C) and volume of mitochondria (D). Asterisks indicate significant differences (*: p<0.05; **: p<0.01; ***: p<0.001). Most parameters are not significantly different between individual animals.

Suppl. Figure 2: Box plots of various synaptic parameters

Data distributions as indicated by the medians (horizontal bars) and interquartile ranges (framed areas) and minimum and maximum (vertical lines) are shown for the surface area of pre- and postsynaptic densities (A), the total pool of synaptic vesicles (B), and vesicle diameter (C). Asterisks indicate significant difference (*: p<0.05; **: p<0.01; ***: p<0.001). Note that between different animals slight but significant differences existed for some parameters.

Suppl. Fig. 3 Box plots of various synaptic parameters

Data distributions as indicated by the medians (horizontal bars) and interquartile ranges (framed areas) and minimum and maximum (vertical lines) are shown for number of synaptic vesicles with the perimeter of 10 nm from the presynaptic density (A), for the 20 nm perimeter (B), for the 60 nm perimeter (C) and the 100 nm perimeter (D). All values are not significantly different between individual animals.