Rebeka Sultana (PhD)

Email:

Lecturer, Dept. of Pharmacy

Stamford University Bangladesh

51, Siddeswari Road,Dhaka-1217, Bangladesh

Qualifications

PhD (Oncology)

Laboratory of Molecular Oncology,Translational DNA Repair Group

School of Molecular Medical Sciences, University of Nottingham

Thesis title: Targeting DNA base excision repair for synthetic lethality

Supervisors: Dr. Srinivasan Madhusudan and Prof. Poulam Patel

M. Sc (Clinical pharmacy and Pharmacology)

Dept. of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy,

University of Dhaka, Bangladesh

Thesis title: Effects of orange juice on bioavailability of levofloxacin

Supervisor: Prof. Dr. Abul Hasnat

Bachelor of Pharmacy

Faculty of pharmacy, University of Dhaka, Bangladesh

Research interests: Identification of new targets for personalised cancer treatment, evaluation of DNA repair factors as therapeutic targets in cancer, exploitation ofdysregulation of DNA repair factors in cancer for personalised treatment, evaluation of DNA damage biomarkers and their application to cancer treatment, elucidation the mechanism of resistance to chemotherapy, pharmacokinetic and bioequivalence studies

Scholarships and awards

  • Awarded PhD scholarship jointly sponsored by Islamic Development Bank (IDB) and University of Nottingham
  • Awarded AstraZeneca student prize from National Cancer Research Institute (NCRI) and AstraZeneca pharmaceuticals for presenting my research work in NCRI Conference, Liverpool, UK (Nov, 2011)
  • Awarded prize for Poster presentation at Postgraduate day, Molecular Medical School, University of Nottingham, Nottingham, UK (June, 2011)

Work experience

  • Lecturer, Dept. of Pharmacy, Stamford University Bangladesh, Bangladesh (2006 -present)
  • Executive, Research Development at Novo Healthcare and Pharmaceuticals, Dhaka, Bangladesh (2005- 2006)

Presentations

  • Oral and Poster Presentation atNational Cancer Research Institute (NCRI), Cancer Conference. Liverpool, UK (Nov, 2011)
  • Oral and poster presentation at postgraduate research day, Molecular Medical School, University of Nottingham, Nottingham, UK (June,2011)

Publications

  • Rebeka Sultana, Tarek Abdel-Fatah, Rachel Abbotts, Claire Hawkes, Nada Albarakati, Claire Seedhouse, Graham Ball, Stephen Chan, Emad A Rakha, Ian O Ellis and Srinivasan Madhusudan- ‘Targeting XRCC1 (X-ray repair cross-complementing gene 1) deficiency in breast cancer for personalized therapy’-Cancer Research, 2013.73 (5):p.14.
  • Tarek Abdel-Fatah, Rebeka Sultana, Rachel Abbotts, Claire Hawkes, Claire Seedhouse, Stephen Chan and Srinivasan Madhusudan-‘Clinicopathological and functional significance of XRCC1 (X-ray repair cross-complementing gene 1) expression in ovarian cancer’- International journal of cancer, 2013.132(12): p.8.
  • Rebeka Sultana, Tarek Abdel-Fatah, Christina Perry, Paul Moseley, Nada Albarakati, Vivek Mohan, Claire Seedhouse, Stephen Chan and Srinivasan Madhusudan-‘Ataxia telangiectasia mutated and Rad3 Related (ATR) protein kinase inhibition is synthetically lethal in XRCC1 deficient ovarian cancer cells’- PLOS ONE, 2013. 8(2): p.9.
  • Rebeka Sultana, Daniel R. McNeill, Rachel Abbotts, Mohammed Z. Mohammed, Malgorzata Z. Zdzienicka,Haitham Qutob, Claire Seedhouse, Charles A. Laughton, Peter M. Fischer, Poulam M. Patel,David M. Wilson,III and Srinivasan Madhusudan- ‘Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors’- International journal of cancer, 2012.131(10): p.12.
  • Rebeka Sultana, Tarek Abdel-Fatah, Nada Albarakati, Rachel Abbotts, Claire Seedhouse, Graham Ball, Stephen Chan, Emad A Rakha, Ian O Ellis and Srinivasan Madhusudan- ‘275 Targeting XRCC1 (X-ray Repair Cross-complementing Gene 1), a Key DNA Base Excision Repair Protein for Personalized Therapy in Breast and Ovarian Cancer’- European Journal of Cancer , 2012.48 (6):p.85.

Alaa T. Alshareeda, Ola H. Negm, Nada Albarakati, Andrew R. Green, Christopher Nolan, Rebeka Sultana, Srinivasan Madhusudan, Ahmed ben Hasouna, Paddy Tighe, Ian O. Ellis, Emad A. Rakha-‘Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer’-Breast cancer research and treatment,2013. 139(2): p.10.

Alaa T. Alshareeda, Ola H. Negm, Andrew R. Green, Christopher Nolan, Paddy Tighe,Nada Albarakati,Rebeka Sultana, Srinivasan Madhusudan, Ian O. Ellis, Emad A. Rakha-‘ SUMOylation proteins in breast cancer’-Breast cancer research and treatment, 2014. 144(3): p.12.

  • Christina Perry, Rebeka Sultana and Srinivasan Madhusudan (2012). Personalized cancer medicine: DNA repair alterations are promising predictive biomarkers in cancer. In Mark R Kelley (Ed.), DNA repair in cancer therapy: Molecular targets and clinical applications (25). Elsevier (Book chapter)
  • Rebeka Sultana, Maruf Mohammad Akbor, Mohammad Abul Kalam Azad, Ashik Ullah, A. H. M. Mahbub Latif and Abul Hasnat. Effect of orange juice on levofloxacin bioavailability. Journal of Applied Research- 8(1), 2008.
  • Md. Ashik Ullah, Mohammad Abul Kalam Azad, Rebeka Sultana, A. H. M. Mahbub Latif andAbul Hasnat. Bioequivalence evaluation of two formulations of amoxicillin capsule in healthyBangladeshi population. Current Therapeutic Research - Clinical and Experimental 69(6):504-513.
  • Md. Ashik Ullah, Shams-ud –Dowla, Abdullah Al Maruf, Mohammad Abul Kalam Azad, Md. Hasanuzzaman Shohag,Rebeka Sultana, A. H. M. Mahbub Latif andAbul Hasnat. Pharmacokinetics, Bioequivalene and tolerability study of two different enteric formulation of esomeprazole in healthy Bangladeshi male volunteers. An open label, single dose, randomozed two way cross over study. Clinical Therapeutics. 32(7): 1419-1429.