37 avenue d’Occitanie
31320 PECHABOU
France
+33 6 2778 78 19
30 August 1986
French citizen
Biochemical engineer /PhD in Immunology
Education2014 / PhD in Immunology - University Paul Sabatier (Toulouse)
2010 / Engineering school diploma – Biochemical engineering (INSA Toulouse)
2010 / Master’s degree in research Microbiology - UPS Toulouse/INSA Toulouse
Languages
French:
English :
Training period: / - Mother Tongue
- Good
- TOEIC: 810
- 3 months in Canada (McGill University (2009))
Work experience
September - December 2014 / Post-Doctoral fellowship atl’IPBS (Toulouse) inJérôme NIGOU team - Immunomodulation by mycobacterial lipids and glycoconjugates.
Study of TLR2 antagonist mycobacterial lipid.
2013-2014 / Teaching assistant (ATER) in University Paul Sabatier.
Biochemistry school teaching for 1st and 2nd year bachelor’s students.
2010-2014 / PhD student in IPBS (Toulouse) in Jérôme NIGOU team - Immunomodulation by mycobacterial lipids and glycoconjugates.
Molecular mechanism inhibition of innate immune response by Mycobacterium tuberculosis – Studies of PRR and molecular immuno-modulator.
January - June 2010 / Research internship in LIT (Lead identification technology) service of Sanofi-Aventis Toulouse with Dr. Hélène Bonnet.
Reporter cell line test miniaturization and optimization for high-throughput screening.
(from 384 wells plate to 1536).
June - September 2009 / Research internship in Department of Food Science and Agricultural Chemistry McGill University (Montréal, Canada) with ProfessorSelimKermasha.
Studies of enzymatic activities implied in pectin degradation.
Competences
Microbiology et Cell Culture / Pathogens Class 3 manipulation
Cell line and primary cell manipulation
Cell culture and sample preparation in microtiter plate 96, 384 and 1536 wells.
Immunology / Stimulation and inhibition ofcell population,
ELISA, Western Blot, Immuno-labelling, Flow cytometry, Confocalemicroscopy
High-throughput screening, robotic,Statistical analysis.
Analytical Biochemistry / Mass spectrometry: MALDI
Capillary electrophoresis, Liquid chromatography,
Thin Layer Chromatography.
Molecular biology / Vector construction, PCR, Bacterial strain transformation,
Complementation, Cosmidsutilization, DNA Extraction from class 3 pathogens.
Computer Science / Good knowledge in hardware, Windows XP, Vista et Seven, Pack Office,
ImageJ, Graph pad Prism5, Flowing software 2, CellQuest Pro,
Algorithmic, Matlab, C++.
Management / Project management, Trainees management, Team working, Pedagogy.
Teaching / Biochemistry lvl1, first year’s bachelor degree, tutorials and practical work, University Paul Sabatier
Biochemistry lvl2, first year’s bachelor degree, tutorials and practical work, University Paul Sabatier
Biochemistry lvl1, second year’s bachelor degree, practical work, University Paul Sabatier.
Publication
Blanc, L., et al, Gram-positive bacterial lipoglycans based on a glycosylateddiacylglycerol lipid anchor are microbe-associated molecular patterns recognized by TLR2. PLoS One, 2013. 8(11): p. e81593.
Presentation/Poster
Blanc, L., et al, Etude des bases moléculaires de la détection de Mycobacteriumtuberculosis par le système immunitaire inné. MycoClub 2, Tours, 2011.
Blanc, L., et al, Molecular mechanism used by Mycobacterium tuberculosis to inhibit innate immune response. From Membranes to Pathologies, 16th GEM-10th GERLI, St-Jean-Cap-Ferrat, 2013.
Miscellaneous
Hobbies / Ski, Snowboard, Tennis, Squash, Computer, Science fiction and fantastic literature.
Autre / Driving license
References
Jérôme NIGOU,
CNRS Directeur de recherche,
+33 (0)5 61 17 55 54
/ Didier COMBES,
Directeur du département «Génie Biochimique» INSA Toulouse,
+33 (0) 5 61 55 94 10
/ Hélène BONNET,
SANOFI-AVENTIS R&D,
Lead Generation France Coordination,
+ 33 (0)1 58 93 39 92
/ Dr. Selim KERMASHA, Department of Food Science and Agricultural Chemistry
001 514-398-7922