Name of Host Institution: <name> / Application Form for Full Proposal
OPEN FUND- LARGE COLLABORATIVE GRANT
(OF-LCG)
MAY 2017 GRANT CALL
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FULL PROPOSAL
CLOSING DATE: 20 Oct 2017 (Fri), 5pm
SUBMISSION DETAILS
To submit three softcopy documents:
· 1 softcopy grant application, with Annexes A – E attached (MS Word doc. format);
· 1 softcopy Annexes F – I (MS Word doc. format); and
· 1 scanned copy of the required signatories- Annex S (PDF format).
Softcopy grant application
· Please use the latest version of the full proposal form “FP-Application ID _PI(HI)” (downloadable from www.nmrc.gov.sg) and name the document in the following format:
FP-Application ID_ Name of Corresponding PI (Name of Host Institution)
(E.g. FP-LCG17MAY035_CSTan(NMRC))
· Softcopy grant application must be saved as a single Microsoft Word document with Annexes A – E attached (note: Annexes A and B are applicable only to renewal applications; Annexes C and D are applicable only to resubmission applications). The document should also include additional annexes, pictures, tables, charts and attachments referred to in the research proposal, if any. Please adhere to the specified number of pages where applicable. There should not be blank or irrelevant pages.
Softcopy Annexes F – I
· Softcopy Annexes F - I must be saved as a single Microsoft Word document.
Scanned copy of the required signatories- Annex S
· Please use the template provided in Appendix 5 of this document for the required signatures, and submit a scanned copy of the signatures in PDF format. Original signatures of the Corresponding PI and Theme PIs and original endorsement by the Corresponding PI’s Institution (i.e. the Host Institution for the OF-LCG) are required. E-signature is acceptable for co-Is and collaborators.
Submission to NMRC
· All applications must be submitted through the Research Office of the Corresponding PI’s institution to the NMRC OF-LCG secretariat at and by the deadline, 20 Oct 2017 (Fri), 5pm.
· Internal Host Institution submission deadline may apply, please check with your Research Office for more information.
· The following will be rejected:
o Incomplete applications e.g. softcopy grant application submission only, missing documents such as re-submission materials required and missing progress/ final reports for renewal applications, missing signatures, sections left blank, missing CVs, etc..
o Outdated application form.
· No late submission or revision to the submitted application will be entertained after the closing date.
· For enquiries, please contact the NMRC OF-LCG secretariat at and .
NMRC OF-LCG FULL PROPOSAL APPLICATION FORM CHECKLIST
1. Corresponding PI & Theme PIs are advised to familiarise themselves with the following documents before applying:
( ) NMRC Research Grants T&Cs (available from www.nmrc.gov.sg)
( ) Budgeting Requirements – please refer the NMRC Guidelines on Management of Funding MOH/NMRC Funding Programmes
2. Application Form (format downloaded from NMRC website) comprising:
( ) Category of Application
( ) Application Details
( ) Field of Research (refer to Appendix 1 of the full proposal application guide for the Health Research Classification System)
( ) Ethical Considerations and Containment
( ) Applicants (submit CVs as Annex F separately from the full proposal application; refer to Appendix 3 of the application guide for the CV templates for (a) the Corresponding PI and Theme PIs and (b) co-Is and Collaborators; max. 3 and 2 pages per applicant for (a) and (b) respectively)
( ) Scientific and Lay Abstract
( ) Research Proposal (max. 3 pages for Section 8.1, max. 4 pages per theme for Section 8.2 (excluding part (ii)), max. 5 pages for Section 8.3, max. 2 pages for Section 8.4; and max. 10 pages for Section 8.5; attach references and section 8.2(ii) for each theme as Annex E to the full proposal application; provide industry support letters as Annex I separately from the full proposal application)
( ) Budget Details (submit completed budget forms as Annex G separately from the full proposal application; refer to Appendix 4 of the application guide for the budget templates)
( ) Industrial Parties’ Contributions
( ) Milestones
( ) Expected Outcomes
( ) Other support (submit scientific abstracts of all grants listed in tables (a) – (d) and supporting documents for part (e) as Annex H separately from the full proposal application; for NMRC funded projects, include, latest research outcomes/ KPIs achieved )
( ) Conflict of Interest
( ) Suggested Reviewers
( ) Undertaking by Research Team and Corresponding PI’s HOD and Institution Director (submit scanned copy of signatories as Annex S separately from the full proposal application; refer to Appendix 5 of the application guide for the undertaking templates)
3. Submission
( ) Document 1- Softcopy grant application, with Annexes A – E attached (MS Word doc. format; save as “FP-Application ID_PI(HI)”)
( ) Document 2- Softcopy Annexes F – I (MS Word doc. format)
( ) Document 3- Scanned copy of signatories required/ Annex S (PDF format; original signature required from Corresponding PI, Theme PIs, HOD of Corresponding PI and Director of the Corresponding PI’s Institution; e-signature acceptable for co-Is and Collaborators)
DEFINITIONS
Overview: The research programme should comprise no more than 5 research themes, each led by one or more Theme Principal Investigators (PIs). All the Theme PIs should form the Leadership Team, and one of the Theme PIs should be nominated as the Corresponding PI.
Leadership Team: Comprises all Theme PIs. The leadership team share the responsibility in making the OF-LCG programme a success and is essential for implementing programme strategies and achieving desired outcomes.
Corresponding PI: The Theme PI who will coordinate the OF-LCG programme, serve as the main point of contact between NMRC and the OF-LCG Leadership Team, and is accountable to NMRC for the proper conduct of the whole programme. He/ She will work closely with the Theme PIs to resolve any issues which arise during the course of the programme, including the usage of funding, any variations to the scope of the programme etc.. Limited to only 1 Corresponding PI per leadership team.
Theme PI: Theme PIs have the responsibility to direct each specific research theme being supported by the grant, and accountable for the proper conduct of the specific research theme. There is no limit on the no. of Theme PIs per theme but a cap of 5 themes applies. An individual can be a Theme PI for multiple themes.
Co-Investigator (Co-I): An individual involved in the scientific development and execution of the project. A co-Investigator typically devotes a higher percentage of effort to the project compared to a collaborator and is considered a key research personnel of the research team. He/ She is required to hold at least an adjunct appointment at a local public institution. There is no limit on the no. of participating co-Is.
Collaborator: An individual involved in the scientific development and execution of project. A collaborator typically devotes only a specific percentage of effort to the project. Researchers from overseas institutions or private companies can only participate as collaborators as well. There is no limit on the no. of participating collaborators.
Administrative core: A team of people involved in the administration of the programme, e.g. programme manager etc.. They are fundable under direct cost and their roles include:
- Overseeing and managing the programme’s administrative matters and activities.
- Reporting directly to the Corresponding PI.
- Liaising with NMRC and other external agencies regarding any programme or grant matters.
APPLICATION FOR THE OPEN FUND LARGE COLLABORATIVE GRANT
All information is treated in confidence. The information is furnished to the National Medical Research Council with the understanding that it shall be used or disclosed for evaluation, reference and reporting purposes. If your application is not successful, this form will be destroyed after the retention period deemed as appropriate by the Council.
1. CATEGORY OF APPLICATION
Please indicate the category of the grant application.
New Submission
Renewal
(Grant number)
Resubmission
(Application ID & No. of resubmissions inclusive of current application)
2. APPLICATION DETAILS
Title (max. 300 characters) / :Name of Corresponding PI / :
Host Institution / :
Funding Request (direct cost) / : / SGD
Funding Request (direct + indirect cost[1]) / : / SGD
Period of support (no. of years)
Key words (max. 6 key words)
3. FIELD OF RESEARCH
Please fill in parts (a) and (b) below, with reference to the Health Research Classification (HRC) System list provided in the Appendix 1 of the application guide. The HRC System is adapted from MRC, UK.
(A) Health Category
You may select up to 5 categories from the following. Please use the minimum number of codes to reflect the main focus of the research.
Blood / MusculoskeletalCancer / Neurological
Cardiovascular / Oral and Gastrointestinal
Congenital Disorders / Renal and Urogenital
Ear / Reproductive Health and Childbirth
Eye / Respiratory
Infection / Skin
Inflammatory and Immune System / Stroke
Injuries and Accidents / Generic Health Relevance
Mental Health / Other
Metabolic and Endocrine
(B) Research Activity Code
You may select up to 2 sub-codes, e.g. 2.1 and 4.1 for each research theme.
Theme no. / Sub-code 1 / Sub-code 2Theme 1
Theme 2
Theme 3
Theme 4
Theme 5
4. ETHICAL CONSIDERATIONS AND CONTAINMENT
Fund disbursement is subjected to ethics approval if the project involves any of the below.
Please tick accordingly if programme involves any of the following: / Please declare the participating institutions where study requiring ethics approval will be conducteda) Human subject / Yes No
b) Use of human material/ animal tissues or cells from primary donors (i.e. subject/volunteers recruited for the project) / Yes No
c) Use of commercially available human material/ animal tissues or cells / Yes No
d) Animal experimentation / Yes No
e) Requirement for containment / Yes No
f) Multi-centre trials(s) / Yes No
A copy of the ethics approvals are as attached / Yes No
5. APPLICANTS
Please note the definitions of the Corresponding PI, Theme PI, co-Investigator (co-I) and Collaborator in page 5 of the application form. Co-Is are required to hold at least an adjunct position in a local public institution. Researchers from overseas institutions or private companies can only participate as collaborators.
Please use the CV templates provided in Appendix 3 of the application guide and submit the completed CVs of all applicants listed in this section as Annex F separately from the full proposal application (but together with Annexes G, H and I; refer to the application guide for submission format details).
Applicant name / Role / Position / Department / InstitutionCorresponding PI
Theme 1 PI
Theme 2 PI
Theme 3 PI
Theme 4 PI
Theme 5 PI
Co-Investigator
(Co-I)
Collaborator
(Please add more rows as required)
6. SCIENTIFIC ABSTRACT
In no more than 300 words, describe the specific aims, hypotheses, methodology and approach of the research proposal including its importance to the furtherance of medical science, in particular clinical significance. The abstract must be self-contained so that it can serve as a succinct and accurate description of the research proposal. Note that the scientific abstract may be disclosed to other funding agencies.
7. LAY ABSTRACT
In no more than 300 words, describe the specific aims, hypotheses, methodology and approach of the research proposal including its importance to the furtherance of medical science, in particular clinical significance. The abstract must be self-contained so that it can serve as a succinct and accurate description of the research proposal. Note that the lay abstract is different from the scientific abstract. It is targeted towards non-technical readers and may be disclosed to the media for the purpose of the announcement of the grant call results.
8. RESEARCH PROPOSAL
This section comprises FIVE sub-sections. Please complete all parts and adhere to the page limit for each sub-section.
Please provide references and completed section 8.2(ii) of all themes as Annex E, and additional documents required for renewal and resubmission applications as Annexes A – B and Annexes C – D respectively if applicable. The annexes do not count towards the page limits for Section 8. Attach these Annexes to the full proposal application. Attach industry support letters required under Section 8.5.2 as Annex I separately from the full proposal application.
8.1 Specific Aims and Hypotheses for the Overall Research Programme
In no more than 3 pages, state concisely what the study intends to accomplish and the hypotheses to be tested. Please also provide a listing of the research themes and respective Theme PIs (using the table below).
Format for listing research themes (note: the number of research themes is capped at FIVE)
Theme no. / Theme Title / Theme PI(s) and InstitutionTheme 1
Theme 2
Theme 3
Theme 4
Theme 5
8.2 Research Themes Proposal
Please provide the information required in parts (i), (iii), (iv) and (v) below in no more than 4 pages per theme for each research theme (note: the number of research themes is capped at FIVE), and part (ii) for each theme as Annex E.
(i) Theme no. and title
(ii) Roles of theme members (refer to Annex E)
Please list the Theme PI, Co-I (s) and Collaborator(s) of the theme in the table provided below. For each individual, indicate their role and expected percentage effort for the theme, measured in terms of work commitment and work contribution.
Note that Co-Investigators need to hold at least an adjunct position in a local public institution. Researchers from overseas institutions or private companies can only participate as collaborators. The terms of collaboration with overseas research institutions and private companies must conform to NMRC’s existing policies.
Name / Role in research theme(Theme PI, Co-I or Collaborator) / Institution / % effort within research theme[2]
Total / 100%
Please also describe the role(s) of each theme member listed above in the box provided below.
(iii) Specific Aims and Hypotheses
State concisely what the study intends to accomplish and the hypotheses to be tested.