LA EXCELLENCE - IAS MEDICAL SCIENCE TEST – 1

DATE:12-SEP-2016

Attempt any of the five questions from below.

Questions 1 and 5 are compulsory.

Out of the remaining three are to be attempted choosing at least one question from each section.

Q1)Answer all of the following questions in 150 words (10*5 = 50MARKS)

A)Describe the features of lymphocytes and their functions. Discuss the conditions associated with their decrease and Increase?

B)Describe sequence of events in Neuro muscular transmission. Discuss the associated pathology with the same. Add a note on the Neurotransmitters.

C)Differentiate between sympathetic and parasympathetic nervous system.

D)Discuss on the renal function tests. What is the significance of GFR and how it can be assessed.

E)Discuss the mechanism of action of following hormones. A) Growth Hormone B) steroids. Elaborate on their physiological role.

Q2)

A)Discuss the factors responsible for the maintenance of Blood pressure. (10 MARKS)

B)Regulation of Heart rate, cardiac output (5M + 5 MARKS)

C)Discuss the pathology of congestive cardiac failure. (10 MARKS)

D)Discuss the changes in cardiac functions in relation to sleep and Exercise.(10 MARKS)

E)Discuss the stages in cardiac cycle.(10 MARKS)

Q3)

Discuss the carcinogenic factors associated with the following cancers

A)Carcinoma Breast . Add a note on BRCA genes. (5+ 5)MARKS

B)Oran cancers – differentiate between various pathological varieties of oral cancers. (20MARKS)

C)What are the functions of placenta. What is the meaning of Feto placental unit. (10MARKS)

D)Discuss different types of Bronchogenic carcinoma and their pathogenesis. (10MARKS)

Q4)

A)discuss the different types of Blood cells and role of the erythropoietin in erythro poises. Add a note on applied aspects. (20 MARKS)

B)Discuss the pre malignant lesions in oral Mucosa.(15MARKS)

C)Discuss the Physiological changes during pregnancy. Add a note on the diagnosis of pregnancy. (15MARKS)

Q5) Answer all the questions

A)What are the differences between acute and chronic inflammation. (5MARKS)

B)Discuss the mediators of acute inflammation. (5MARKS)

C)Discuss the Pathogensis of Hypersensitivity. Classify them. (10MARKS)

  1. What is the physiology of menstruation and lactation. Discuss the role played by various harmones in the same. (15MARKS)

A)What is metastasis. Discuss the factors responsible for Metastasis. (5MARKS)

B)Differentiate between primary and Metastatic malignancies. (5MARKS)

C)Differentiate between the benign and malignant tumors (5MARKS)

Q6)discuss the mechanics of action of the following drugs

  1. Anti Malarials (20MARKS)
  2. Anti Tubercular drugs (20MARKS)
  3. Anti viral drugs (10MARKS)

Q7)

  1. discuss the mechanism of action and side effects of anti hypertensive drugs. Write a note on the anti hypertensive drugs used in diabetic patients. (20MARKS)
  2. Write a note on the mechanism of action of the following – Glyceraltrinitrate, Nifedipine. Add a note on their pharmacological applications. (20MARKS)
  3. Discuss the mechanism of action of Metformin and discuss on the new drugs used in the management of Diabetes. (10MARKS)

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