AP Biology Semester 1 Study Guide
AP Biology Semester 1 Study Guide / January 192016
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Unit I: Chemistry of Life (Chapters 2, 3, and 6)
Chemistry
- Draw and describe the following types of bonds:
- Ionic
- Covalent (polar and non-polar covalent)
- Hydrogen
- Give an example of a compound/molecule that displays each type of bond listed above.
Water
- List five properties of water. Define each property. Explain how each property is advantageous for a particular organism. Be specific in your examples.
Organic Molecules
- What is an organic molecule?
- What is the difference between a monomer and a polymer?
- What are functional groups? List the functional groups studied in class. Draw a picture of each type of functional group. Provide an example of a molecule in which each functional group can be found.
Carbohydrates
- Draw a monosaccharide (the monomer of all carbohydrates).
- What is the formula for glucose?
- Draw and give the function for the following carbohydrates.
- Sucrose
- Starch
- Cellulose
- Glycogen
- Chitin (You don’t have to draw this one)
- In what types of foods do you find carbohydrates?
Lipids
- Draw and give the function for the following lipids.
- Triglycerides (fats…saturated and unsaturated)
- Phospholipids
- Steroids (cholesterol and sex hormones)
Proteins
- Draw an amino acid (the monomer of a protein).
- Give the five major groups of proteins and one example of how each group is used in the body.
- How are amino acids joined together?
- Draw and describe the following protein structures.
- Primary
- Secondary (alpha helix and beta pleated) (fibrous)
- Tertiary (globular) Give the three types of bonds that help form the tertiary structure and explain the hydrophobic effect.
- Quaternary structure
Nucleic Acids
- Draw a nucleotide (the monomer of nucleic acids).
- Give the five types of nitrogen bases and identify them as purines or pyrimidines. (AGriculture is pure… or AG—“always glow”)
- Draw a simplified molecule of RNA and one of DNA and give the basic functions of each.
Enzymes
- Enzymes are globular, quaternary structured proteins. What is the main function of an enzyme?
- What is activation energy and how do enzymes affect the activation energy in a reaction?
- What is the difference between catabolism and anabolism? Together, these reactions are referred to as metabolism.
- Draw a picture of an enzyme catalyzed reaction and label the following.
- Substrate, active site, enzyme, enzyme-substrate complex, products
- Why do enzymes follow the so-called lock and key model or induced fit model?
- Give an example of three enzymes and their substrates. How do you know which one is the enzyme, if only given the names?
- How can improper pH and/or temperature affect enzyme function?
- Give an example of a coenzyme and a cofactor and describe how each works.
- Enzyme Inhibitors: Explain how competitive, noncompetitive and allosteric inhibitors work and draw an example of how each works.
- Describe the concept of negative feedback with regards to enzyme function.
Unit II: The Cell (Chapters 4-5)
Cell Classification
- What is the difference between a prokaryote and a eukaryote?
- Give examples of each.
- Give four differences between plant and animal cells.
Cell Membrane Structure
- Draw a section of the plasma membrane and label the following…Beside each label, provide the function of each structure
- Phospholipids
- Hydrophilic heads
- Hydrophobic tails
- Cholesterol
- Integral and transmembrane proteins: channel, transport, electron transport (see chemiosmosis)
- Peripheral proteins: recognition, receptor, and adhesion
Cell organelles
- Cut and paste a picture of the plant and the animal cell and beside each label listed below, provide the functions of the organelles. You may need to draw some in.
- Nucleus
- Ribosomes,
- Rough ER
- Smooth ER
- Golgi body
- Vesicles
- Mitochondria
- Chloroplasts
- Lysosomes
- Centrioles
- Vacuoles
- Flagella
- Cilia
- Cell Wall
- Cut and paste your drawings of the cell junctions and give examples of cells that display each type of junction.
Cell Membrane Function
- What does it mean that the cell membrane is selectively permeable?
- Create a chart comparing the following processes: diffusion, osmosis, facilitated diffusion, and active transport.
Include the following in your chart:
- passive or active
- with or against the gradient
- proteins or no proteins involved
- if proteins are involved, what type
- substances moved by each process
- Draw a cell in a hypertonic, hypotonic, and isotonic solution
- Describe the process of plasmolysis
- Vesicular transport: Draw the processes of exocytosis, endocytosis (phagocytosis and pinocytosis)
Unit III: Cell Processes: Energy and Communication (Chapters 7-8)
Cell Respiration
- Give the formula
- All organisms undergo glycolysis in their cytoplasm. What is glycolysis?
- All eukaryotes undergo chemiosmosis in their mitochondria. Why don’t prokaryotes?
- Describe the basic structure of ATP and describe the energy cycle between ADP and ATP.
Glycolysis
- Glucose is broken down into ______.
- How many ATP’s are invested? What is the net yield of ATP?
- How many NADH are produced?
- Where does this occur?
Kreb’s Cycle (aka Citric Acid Cycle)
- What are the 2 pyruvates converted into before they can enter the citric acid cycle?
- What is released in the process?
- How many ATP’s are released?
- How many NADH’s? Where do they go?
- How many FADH2’s? Where do they go?
- In animal respiration, what happens to the CO2 that is released?
- Where does this occur?
Electron Tranport Chain
- Why is this process called chemiosmosis or oxidative phosphorylation?
- What do the NADH and the FADH2 do for this process?
- Describe the ETC. Be sure to include NADH, FADH2, cytochrome carrier proteins, H+ ions, concentration gradient, pump, ATP synthase, ADP, ATP, oxygen as the final electron acceptor.
- What is produced when oxygen accepts the final electons?
- How many ATP’s are produced?
- Where does this occur?
Anaerobic Respiration
- What happens if no oxygen is present in the cell after glycolysis?
- What is the difference between anaerobic respiration in animals vs. anaerobic respiration in plants, yeast, and bacteria?
- What is another name for anaerobic respiration?
Photosynthesis
- Give the equation for photosynthesis.
- What types of organisms undergo photosynthesis?
- What is the purpose of photosynthesis?
Light Reaction (aka Noncylic photophosphorylation)
- Provide a flowchart for the steps of the light reaction. It might be nice to draw the steps too. Include the following terms:
- photosystem II (P680)
- photolysis
- primary electron acceptor
- electron transport chain
- ADP-ATP
- Photosystem I (P700)
- Primary electron acceptor
- Electron transport chain
- NADP-NADPH
- Where do all of these steps occur?
- What is cyclic photophosphoylation?
Calvin Cycle (aka Dark Reacations)
- Provide a flowchart for the steps of the Calvin cycle. It might be nice to draw the steps too. Include the following terms:
- Carbon fixation
- Rubisco
- CO2
- RuBP
- PGA (3C)
- Glucose (6C)
- Where does this process take place?
C4 and CAM Photosynthesis
- What happens when there is not enough carbon dioxide entering the leaf?
- C4 Photosynthesis: A 2 step process where carbon is fixed in two different cells
Draw a flowchart for C4 photosynthesis and include the following:
Mesophyll cells
PEP Carboxylase
4C “storage” compounds (oxaloacetate)
Bundle sheath cells
Rubisco
Calvin Cycle
- Which plants undergo C4 photosynthesis?
- CAM Photosynthesis: A 2 step process where carbon is fixed at different times of the day. Draw a flowchart for CAM photosynthesis and include the following:
- Stomates open
- Night
- Carbon “storage” compound
- Day
- Stomates closed
- Calvin Cycle
- CO2
- Which plants undergo CAM photosynthesis?
Unit IV: From Gene to Protein (Chapters 9-12)
Cell Cycle
- Name the four functions of cell division (mitosis)
- Which cells divide by mitosis?
- Distinguish between the following terms and name the phase of the cell cycle in which you would find these structures.
- Chromosomes
- Chromatids
- Centromere
- Complementary strands
- What happens during G1, S, G2, and GO of interphase?
- Name the major events of prophase, metaphase, anaphase and telophase.
- How is cytokinesis different in animal cells and plant cells?
- How are the following involved in cell division…
- Surface to volume ratio
- Density dependent inhibition
- Checkpoints
Meiosis
- Which cells divide by meiosis?
- Meiosis I: List the phases of meiosis I and include the following terms as you describe the phases.
- Reduction division
- Homologous chromosomes
- Diploid
- 2n
- Crossing Over
- Tetrad
- Synapsis
- Independent assortment
- Meiosis II: List the phases of meiosis II and include the following terms as you describe the phases.
- Haploid
- 1n
- Sister chromatids
- Which process produces genetic variation and recombination, mitosis or meiosis?
Heredity
- Define or describe the following Mendelian inheritance terms. Draw, or include a sample punnett square problem, for each of these terms.
- Locus
- Gene
- Allele
- Homologous pairs
- Dominant
- Recessive
- Phenotype
- Genotype
- Homozygous
- Heterozygous
- Monohybrid cross
- Dihybrid cross
- P, F1, F2 generations
- Test cross
- Describe the following rules and laws of Mendel’s and give examples of each.
- Dominance
- Segregation
- Independent Assortment
- Define or describe the following non-Mendelian Inheritance patterns. Draw, or include a sample Punnett square problem, for each of these terms.
- Incomplete dominance
- Codominance
- Multiple alleles
- Epistasis
- Pleiotropy
- Polygenic inheritance
- Linkage
- Sex-linked
- X inactivation
- Non-disjunction
- Deletion
- Duplication
- Translocation
- Inversion
DNA Replication
- Describe the steps for DNA Replication by creating a flowchart. Use the following terms in your description.
- Semiconservative replication
- Template strand
- DNA polymerase
- Leading strand
- Lagging strand
- Helicase
- Replication fork
- Single stranded binding proteins
- DNA ligase
- Okazaki fragments
- RNA primase
- RNA primer
- 3’ and 5’ ends
- Where in the cell does replication occur?
- Draw examples of the following types of gene mutations
- Point (aka substitution)
- Frameshift (insertion and deletion)
Protein Synthesis
- Describe the experiment that led to the one-gene-one-enzyme hypothesis (one-gene-one-polypeptide)
- Describe the steps of transcription while including the following terms
- mRNA
- RNA polymerase
- RNA processing
- Introns
- Exons
- 5’ cap
- Poly-A tail
- Splicesomes
- Where in the cell does transcription occur?
Translation
- Describe the steps of translation while including the following terms
- mRNA
- codon
- tRNA
- anticodon
- rRNA
- ribosome
- small RNA subunit
- large RNA subunit
- P site
- A site
- Wobble
- Stop Codon
- Start Codon (Met)
- Initiation
- Elongation
- Termination
- Where in the cell does translation occur?
- Name three ways that replication and protein synthesis are different in prokaryotic and eukaryotic cells.