Hyperthermia Ozone Therapy

In a 2009 study done by one of the leading authorities in Ozone Therapy, Professor Velio Bocci of Sienna University in Italy, a 20 minute Ozone Sauna session delivered the following results:

  • There was a significant increase in body temperature, which reached a peak at the end of the treatment and declined rapidly thereafter. Maximum oral temperature ranged between37.5 and 39.3
  • There was a concomitant reduction in body mass (200 – 600g)
  • Blood pressure decreased slightly, but recovered within the next 30 – 60 minutes
  • There was a significant increase of O2 venous partial pressure at the end of the session and for about 1 hour after. This indicated that oxygen had been absorbed via the skin.
  • Values for both erythrocytes (Red Blood Cells) and haematocrit (% of red blood cells) increased immediately after the 20 minute session. They decreased thereafter, probably due to rehydration and were almost normal after 24 hours.
  • There was a significant increase in leukocytes (White Blood Cells), followed by a decrease 1 hour after.
  • The experimental data regarding the plasma levels, modifications of total antioxidant, peroxidation values measured as Thiobarbituric Acid Reactive Substances (In the Brain) and protein-thiol groups oxidation were surprising:-
  • Antioxidants declined but remained at a substantial level
  • Peroxidation levels increased steeply up to an hour after the end of the session
  • Protein-thiol groups declined during the same period
  • No haemolysis (Red blood cells releasing haemoglobin) was noted at any time
  • Levels of IL-8 (Immune System Reaction) significantly increased 30 minutes after exposure
  • Levels of myeloperoxidase (Pre-oxidase enzyme) and transforming growth factor either did not change or tended to decrease
  • Plasma levels of hepatic enzymes and creatinine (Renal Function Measurement) remained within the normal range
  • Ozone clearly accounts for the significant linear increase of peroxidation values measured up to an hour after the session
  • We did not observe any acute or chronic toxicity and no toxicity after repeated therapy has been noted.
  • None of the volunteers, nor several patients have reported acute or late side effects
  • Ozone toxicity for the respiratory tract – some precautions: The cabin must be tightly closed, the room must be well ventilated and ozone must be turned off before the client leaves the unit
  • Why do the clients feel so good?This could be attributed to the hyperthermia. We found that the short-term hormonal changes during and after sauna bathing, particularly the described increase of growth hormone and beta endorphin, are quite interesting. Long term sauna bathing helps to lower blood pressure.

Does Hyperthermia Ozone have some advantages?

1.1The activation of the immune system may be useful in chronic viral diseases (HBV, HCV, Herpes1 and 2, HIV HPV). It may be proficient to treat chronic fatigue syndrome even though it is probably not a viral disease.

1.2Metastatic cancer, to avoid palliative chemotherapy, which is usually associated with negative prognosis. However, it could be even tried as an immune-adjuvant at earlier stages with polychemotherapy. It may be possible to improve the quality of life.

1.3Vasculopathies, particularly hind limb ischaemia due to atherosclerosis, Bueger disease and diabetes. Necrotic ulcers and dystrophic lesions must be stimulaneously treated with topical therapy. Patients with severe coronary atherosclerosis, recent myocardial infarction or severe hypertension may undergo therapy BUT without hyperthermia, starting with a 10 minute period and scaling up slowly. Patients with asthma and BPCO must also be treated cautiously. However it can be added that vasculopathies are positively sensitive to ozonetherapy.

1.4Age related macular degeneration, exclusively the atrophic form. Keeping the heat at a low level.

1.5Sclerodermia with Raynaud’s phenomenon.

1.6Moderate burns, to prevent or reduce bacterial infections and enhance healing.

1.7Some muscular-tendinous lesions in athletes, to reduce muscle contraction and alleviate pain.

1.8Skin disease such as infections, psoriasis, perhaps atopic dermatitis and eczema.

1.9Advanced lipodystrophies, such as Madelund disease. The Lipodystrophy occurring during highly active anti-retroviral therapy may also be advantageously treated.

Our provisional protocol envisages a course of 2 – 3 treatments weekly during the first and second weeks but it must be taken into account the patients age, stage and type of disease. We always insist on the “start low, go slow” paradigm to allow for the adaptation to Chronic Oxidative Stress. The heating should be gradually scaled up from 30 degrees to no more than 42 degrees with periods from 10 minutes to a maximum of 30 minutes. Normal subjects interested in using Ozone Steam Sauna Therapy as an anti-aging approach may afford to do 5 treatments weekly spending 30 – 35 minutes in the cabinet.

Contraindications for Ozonetherapy

a)People with a significant deficit in G-6PD (An enzyme that helps red blood cells function normally). Favism is ahaemolytic disease observed in some people lacking the enzyme

b)PREGNANCY

c)Patients being treated with Angiotensin-converting Enzymes (Used to treat high blood pressure, Heart Failure, Diabetic Nephropathy, Type 2 Diabetes)

d)Abnormal situations with hyperthyroidism, thrombocytopenia and serious cardio vascular instability