AM: Arithmetic Mean, GM:Geometric Mean

visit / N / AM / GM / Percentile / N(%)
0(Min) / 25th / 50th / 75th / 100(Max)
BPA / First / 558 / 1.23 / 0.63 / 0.004 / 0.352 / 0.672 / 1.286 / 15.201 / Overweight / 242(43.3)
Second / 471 / 1.62 / 0.74 / 0.002 / 0.476 / 0.857 / 1.455 / 135.923 / 216(45.9)
Third / 316 / 1.34 / 0.78 / 0.012 / 0.449 / 0.808 / 1.448 / 35.157 / 136(43.0)
Fourth / 181 / 0.85 / 0.46 / 0.004 / 0.254 / 0.504 / 0.956 / 8.905 / 82(45.3)
Fifth / 45 / 1.77 / 0.85 / 0.009 / 0.496 / 0.809 / 1.588 / 24.354 / 22(48.9)
Total / 1571 / 1.34 / 0.67 / 0.002 / 0.379 / 0.736 / 1.343 / 135.923 / 698(44.4)

Supplemental Material, Table 1. The distribution of BPA(μg/g of creatinine) and frequency of overweight at each visit or all.

AM: Arithmetic mean, GM:geometric mean

Supplemental Material, Table 2. Correlation between a single measurement and five sample average measurement of BPA

Correlation with five-sample average
BPA
First-visit (n=558) / Coefficient / 0.36
p-value / <.0001
Second-visit (n=471) / Coefficient / 0.95
p-value / <.0001
Third-visit (n=316) / Coefficient / 0.62
p-value / <.0001
Fourth-visit (n=181) / Coefficient / 0.37
p-value / <.0001
Fifth-visit (n=45) / Coefficient / 0.76
p-value / <.0001
Total (n=1571) / Coefficient / 0.70
p-value / <.0001

Supplemental Material, Table 3. Odds ratios for overweight according to quartile average bisphenolA levels using generalized estimating equations model.

OR(95% CI)
Not adjusted
Total (n=1571) / Women(n=1189) / Men(n=382)
Quartile 1 / reference / reference / reference
Quartile 2 / 1.43(1.05, 1.95) / 1.69(1.19, 2.40) / 0.86(0.44, 1.66)
Quartile 3 / 1.26(0.96, 1.65) / 1.36(1.00, 1.85) / 0.99(0.56, 1.73)
Quartile 4 / 1.35(1.01, 1.81) / 1.53(1.09, 2.14) / 0.91(0.51, 1.63)
Age and sex adjusted
Quartile 1 / reference / Reference / Reference
Quartile 2 / 1.43(1.05, 1.95) / 1.68(1.18, 2.39) / 0.86(0.44, 1.66)
Quartile 3 / 1.25(0.96, 1.64) / 1.35(0.99, 1.83) / 1.00(0.57, 1.75)
Quartile 4 / 1.35(1.01,1.80) / 1.52(1.09, 2.14) / 0.93(0.52, 1.66)
Additional adjusted*
Quartile 1 / Reference / Reference / Reference
Quartile 2 / 1.42(0.94, 2.15) / 1.64(1.04, 2.59) / 0.87(0.34, 2.19)
Quartile 3 / 1.43(0.99, 2.07) / 1.79(1.17, 2.73) / 0.65(0.27, 1.60)
Quartile 4 / 1.41(0.95, 2.09) / 1.66(1.04, 2.65) / 0.88(0.41, 1.89)

* Additionally adjusted by age, sex, low-density lipoprotein cholesterol level, alcohol consumption, regular exercise, total calorie intake, fatty acid intake, urinary cotinine concentrations and diabetes.

Supplemental Material, Table 4. Odds ratios for overweight according to log-transformed bisphenolA levels per interquartile range increase after exclude extreme values of urinary bisphenol A.

log BPA
OR(95%CI)
Total(n=1540) / Women(n=1165) / Men(n=375)
Not adjusted / 1.15(1.03, 1.27) / 1.17(1.04, 1.32) / 1.03(0.83, 1.26)
Age and sex adjusted / 1.14(1.02, 1.26) / 1.17(1.04, 1.32) / 1.03(0.84, 1.27)
Additional adjustment* / 1.16(1.02, 1.33) / 1.22(1.04, 1.42) / 1.02(0.79, 1.32)

Supplemental Material, Table 5. Odds ratios for overweight according to quartile bisphenolA levels after exclude extreme values of urinary bisphenol A.

OR(95% CI)
Not adjusted
Total (n=1571) / Women(n=1189) / Men(n=382)
Quartile 1 / reference / reference / reference
Quartile 2 / 1.48(1.10, 1.98) / 1.50(1.06, 2.12) / 1.40(0.81, 2.44)
Quartile 3 / 1.34(1.01, 1.77) / 1.52(1.10, 2.10) / 0.89(0.50, 1.60)
Quartile 4 / 1.45(1.07, 1.96) / 1.66(1.17, 2.37) / 0.93(0.52, 1.68)
Age and sex adjusted
Quartile 1 / reference / Reference / Reference
Quartile 2 / 1.49(1.11, 2.00) / 1.51(1.07, 2.13) / 1.38(0.79, 2.41)
Quartile 3 / 1.33(1.00, 1.77) / 1.51(1.09, 2.08) / 0.89(0.50, 1.61)
Quartile 4 / 1.45(1.07, 1.96) / 1.66(1.16, 2.37) / 0.94(0.52, 1.70)
Additional adjusted*
Quartile 1 / Reference / Reference / Reference
Quartile 2 / 1.48(1.03, 2.13) / 1.52(1.00, 2.30) / 1.41(0.67, 2.93)
Quartile 3 / 1.41(0.96, 2.08) / 1.75(1.13, 2.71) / 0.56(0.21, 1.48)
Quartile 4 / 1.49(0.99, 2.24) / 1.70(1.05, 2.75) / 0.97(0.44, 2.13)

Supplemental Material, Table 6. Odds ratios for overweight according to log-transformed bisphenolA levels per interquartile range increase after weighting inverse probability of attaining a follow-up response.

log BPA
OR(95%CI)
Total(n=1540) / Women(n=1165) / Men(n=375)
Not adjusted / 1.16(1.06, 1.27) / 0.96(0.94, 0.98) / 1.02(0.85, 1.22)
Age and sex adjusted / 1.15(1.05, 1.26) / 1.19(1.07, 1.32) / 1.02(0.85, 1.22)
Additional adjustment* / 1.17(1.03, 1.33) / 1.26(1.09, 1.46) / 0.92(0.73, 1.17)