Manuscript JTRM-D-16-0344

Manuscript JTRM-D-16-0344

Reading keys for database 1

Database 1 contains data concerning 44 patients, 32 with diagnosis of IgA nephropathy (IgAN) and 12 with diagnosis of minimal change disease (MCD) at the time of biopsy (Tob).

Columns

A: Patient ID, patient identification

B: Sex, male =1; female = 2

C: Age at the time of biopsy

D: Date of birth

E: Year of the biopsy

F: Diagnosis, IgAN = 1; MCD = 2

G: Follow up data, availability of follow-up data, yes = 1; no = 2

H: Haematuria at the time of biopsy (1= gross haematuria, 2 = microscopic haematuria, 3= no haematuria)

I: Proteinuria at the time of biopsy (g/24 hours)

J: Serum creatinine values at the time of biopsy (mg/dl)

K: Hypertension,values at the time of biopsy , * in treatment for hypertension

L: Hypertension at the time of biopsy, 1= yes, 2 = no

M: estimated glomerular filtration rate at the time of biopsy

N: Stage according to Kidney Disease Outcome Quality Initiative (KDOQI) at the time of biopsy

O: C3 immune-fluorescence, 1= yes; 2 = no

P: Diffuse C3 immune-fluorescence, 1= yes; 2 = no

Q: Focal C3 immune-fluorescence, 1= yes; 2 = no

R: Imunoglobulin (Ig) G immune-fluorescence, 1= yes; 2 = no

S: Diffuse IgG immune-fluorescence, 1= yes; 2 = no

T: Focal IgG immune-fluorescence, 1= yes; 2 = no

U: Focal and negative IgG immune-fluorescence, 1= yes; 2 = no

V: Ig A immune-fluorescence, 1= yes; 2 = no

W: Diffuse Ig A immune-fluorescence, 1= yes; 2 = no

X: Focal Ig A immune-fluorescence, 1= yes; 2 = no

Y: IgM immune-fluorescence, 1= yes; 2 = no

Z: Diffuse IgM immune-fluorescence, 1= yes; 2 = no

AA: Focal IgM immune-fluorescence, 1= yes; 2 = no

AB:Focal and negativ IgM immune-fluorescence, 1= yes; 2 = no

AC: Fibrinogen immune-fluorescence, 1= yes; 2 = no

AD: Diffuse fibrinogen immune-fluorescence, 1= yes; 2 = no

AE: Focal fibrinogen immune-fluorescence, 1= yes; 2 = no

AF: Focal and negative fibrinogen immune-fluorescence, 1= yes; 2 = no

AG: Mean number of glomerular CD68+ macrophages

AH: Mean number of interstitial CD68+ macrophages per high power field

AI: M value = Mesangial hypercellularity values (Oxford classification)

AJ: M score = Mesangial hypercellularity scores (0, 1; Oxford classification)

AK: S = segmental glomerulosclerosis scores(0, 1; Oxford classification)

AL: T = tubular atrophy scores(0, 1; Oxford classification9

AM: G = grade (1, 2, 3; 3-grade classification)

AN: Endothelial cell area (%)