Acetaminophen(variousTylenol®products)Acetaminophen/aspirin(Excedrin®BackandBody)Acetaminophen/aspirin/caffeine(variousExcedrin®products)

Angiotensin-ConvertingEnzymeInhibitors(ACE-I):(migraineprophylaxis-off-label)

  • Enalapril(Vasotec®)
  • Lisinopril(Prinivil®,Zestril®)

Anticonvulsants:

  • Carbamazepine(Carbatrol®,Epitol®,Tegretol®,TegretolXR®)
  • Divalproexsodium(Depakote®,DepakoteER®)
  • Gabapentin(Gralise®,Horizant®,Neurontin®)
  • Lacosamide(Vimpat®)-off-label
  • Lamotrigine(Lamictal®,LamictalODT®,LamictalXR®)-off-label
  • Levetiracetam(Keppra®,KeppraXR®)-off-label
  • Oxcarbazepine(Trileptal®)-off-label
  • Phenytoin(Dilantin®)
  • Pregabalin(Lyrica®)
  • Topiramate(Topamax®,TrokendiXR®)
  • Valproicacid(Depakene®)
  • Zonisamide(Zonegran®)-off-label

Antidepressants:

  • Amitriptyline
  • Bupropionhydrochloride(Wellbutrin®,WellbutrinXL®,WellbutrinSR®ForfivoXL®,Zyban®)-off-label
  • Bupropionhydrobromide(Aplenzin®)-off-label
  • Clomipramine(Anafranil®)
  • Desipramine(Norpramin®)
  • Doxepin-off-label
  • Duloxetine(Cymbalta®)
  • Fluoxetine(Prozac®,ProzacWeekly®,Sarafem®)
  • Fluvoxamine-off-label
  • Imipramine(Tofranil®,Tofranil-PM®)-off-label
  • Maprotiline-off-label
  • Milnacipran(Savella®)
  • Mirtazapine(Remeron®)-off-label
  • Nortriptyline(Pamelor®)-off-label
  • Paroxetine(Paxil®,PaxilCR®)-off-label
  • Sertraline(Zoloft®)-off-label
  • Venlafaxine(EffexorXR®)-off-label

BetaBlockers(migraineprophylaxis):

  • Atenolol(Tenormin®)
  • Bisoprolol(Zebeta®)-off-label
  • Metoprolol(Lopressor®)
  • Nadolol(Corgard®)-off-label
  • Nebivolol(Bystolic®)
  • Pindolol-off-label
  • Propranolol(InnopranXL®,InderalLA®)
  • Timolol

CalciumChannelBlockers:

  • Nicardipine(migraine-off-label)
  • Nimodipine(clusterheadache-off-label)
  • Verapamil(Calan®,CalanSR®,Verelan®,VerelanPM®):(migraineprophylaxis)

ErgotAlkaloid

  • Dihydroergotamine(Migranal®)-nasalspray

NonsteroidalAnti-inflammatoryDrugs(NSAIDs):

  • Aspirin
  • Celecoxib(Celebrex®)
  • Diclofenac(Voltaren®)-gel
  • Diclofenac(Dyloject®)-injection
  • Diclofenac(Cambia®,VoltarenXR®,Zipsor®,Zorvolex®)-oral
  • Diclofenac(Pennsaid®)-topicalsolution
  • Diclofenac(Flector®)-transdermalpatch
  • Diclofenac/misoprostol(Arthrotec®)
  • Diflunisal
  • Etodolac
  • Fenoprofen(Nalfon®)
  • Flurbiprofen
  • Ibuprofen
  • Ibuprofen/famotidine(Duexis®)
  • Indomethacin(Indocin®,Tivorbex®)
  • Ketoprofen
  • Ketorolac-oral,injection
  • Ketorolac(Sprix®)-nasalspray
  • Meclofenamate
  • Mefenamicacid(Ponstel®)
  • Meloxicam(Mobic®,Vivlodex®)
  • Nabumetone
  • Naproxen(Naprosyn®,NaprelanCR®)
  • Naproxen/esomeprazole(Vimovo®)
  • Oxaprozin(Daypro®)
  • Piroxicam(Feldene®)
  • Salsalate
  • Sulindac
  • Tolmetin

NeuromuscularBlockers

  • onabotulinumtoxinA(Botox®)
  • abobotulinumtoxinA(Dysport®)
  • rimabotulinumtoxinB(Myobloc®)
  • incobotulinumtoxinA(Xeomin®)

Serotonin5HT-1agonist(Triptans)

  • Almotriptan(Axert®)-oral
  • Eletriptan(Relpax®)-oral
  • Frovatriptan(Frova®)-oral
  • Naratriptan(Amerge®)-oral
  • Rizatriptan(Maxalt®,MaxaltMLT®)-oral
  • Sumatriptan(Alsuma®,Imitrex®,OnzetraXsail®,SumavelDosepro®,Zecuity®,ZembraceSymtouch®,Zomig®,ZomigZMT®)-injection,nasalpowder,nasalspray,oral,transdermal
  • Sumatriptan/naproxen(Treximet®)-oral
  • Zolmitriptan(Zomig®,ZomigZMT®)-nasalspray,oral

SkeletalMuscleRelaxants:

  • Chlorzoxazone(Lorzone®)
  • Cyclobenzaprine(Flexeril®)
  • Metaxalone(Skelaxin®)
  • Methocarbamol(Robaxin®)
  • Orphenadrine(Norflex®)

TopicalAnesthetics:

  • Capsaicincream,gel,lotion,jelly
  • Capsaicin(Qutenza®)-transdermalpatch
  • Lidocainejelly,ointment
  • Lidocaine(Lidoderm®)-transdermalpatch
  • Lidocaine/prilocainegel