MAGU HDSS, TANZANIA

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Brief Introduction to MAGU HDSS

Magu HDSS is one of the research components of the Kisesa Open Cohort Study implemented in Kisesa ward Magu District. The cohort was established in April 1994 with the aim of monitoring progression and Impact of HIV/AIDS epidemic and developing relevant interventions in response. The cohort is therefore based on Demographic Surveillance System, Epidemiological Sero-survey, quarterly Antenatal Clinic Surveillance, VCT&ARVs services and qualitative studies.

Objectives

  • To measure child and adult mortality and fertility in the general population and by HIV status
  • To lay a reliable foundation for epidemiological surveys by registering people's mobility and mortality
  • To assess the leading causes of death through verbal autopsy (and death certificates if possible)
  • To assess the potential changes in family structure due to the adult mortality (e.g. orphanhood)
  • To provide Vital Data to the Ward and District authorities for planning purposes
  • To monitor progression and impact of HIV/AIDS epidemic
  • To assess uptake and impact of ARVs

Priority Research Areas

  • Demographic surveillance:
  • Monitoring of the basic demographic variables i.e. Fertility, Mortality and Mobility
  • HIV/AIDS:
  • Monitoring Progression and Dynamics of HIV/AIDS both in the general population and antenatal women
  • Assessment of the Impact of HIV/AIDS Epidemic with focus on the child and adult mortality, orphanhood
  • Assessment of the uptake and Impact of ARVs

Completed Key Projects (Up to 10)

S/N / Project Name / Funder / Grant Period
1. / Demographic baseline survey and follow-ups (21 rounds) / Netherlands Government &Global Fund & DFID
2. / Mobility as an important risk factor for HIV infection / European Union / 2000-2003
3. / Secretive females or swaggering males? An assessment of the quality of sexual partnership reporting in rural Tanzania / Netherlands Government / 1999-2001
4. / Sexual discourse in the context of AIDS: Dominant themes on adolescent sexuality among primary school pupils in Magu district, Tanzania / Netherlands Government / 1994-1996
5. / Male circumcision and susceptibility to HIV infection among men in Tanzania / Netherlands Government / 1994-1997
6. / Situation of orphans and their care providers in rural Tanzania / Community REACH/UNICEF / 2005-07
7. / Barrier to uptake of ARVs in rural Tanzania / Mellon Foundation / 2005-07
8. / Antenatal Clinic surveillance in the era of ARVs / WHO / 2007-07

Ongoing Key Projects (Up to 10)

Project Name / Funder / Grant Period
Community uptake and impact of ART / Global Fund Round 4 / 2005-2010
  • Demographic Surveillance
/ Global Fund Round 4 / 2005-2010
  • Epidemiological Sero-surveys
/ Global Fund Round 4 / 2005-2010
  • Qualitative studies
/ Global Fund Round 4 / 2005-2010
  • VCT Services
/ Global Fund Round 4 / 2005-2010
  • Referral to access ARVs in hospitals
/ Global Fund Round 4 / 2005-2010
Antenatal Clinic Surveillance / Global Fund Round 4 / 2005-2008
Qualitative research / Global Fund Round 4 / 2005-2008

Planned Projects (Up to 5)

Project Name / Funder / Grant Period
Continue with improved;
  • Demographic Surveillance
/ Global Fund / 2008-2020
  • Epidemiological Sero-surveys
/ Global Fund / 2008-2020
  • Qualitative studies
/ Global Fund / 2008-2020
  • VCT Services
/ Global Fund / 2008-2020
  • Referral to access ARVs in hospitals
/ Global Fund / 2008-2020
Biomedical project to improve data processing infrastructure / Wellcome Trust/Global Fund / 2008-2010
Household, family and partnership dynamics and HIV in Tanzania / Wellcome Trust / 2009-2012
District-wide facility survey / Global Fund / 2010 onwards
Genotypic research project / Global Fund / 2009

Human Resource at the site (Grouped by Major Categories)

CATEGORIES / NUMBER
Mr. John Changalucha / Director NIMR Mwanza Centre / 1
Mr. Mark S. Urassa / Co-ordinator Kisesa Cohort (including the Magu DSS) / 1
Mr. Raphael Isingo / Magu DSS Statistician / 1
Mr. Milalu Ndege / Supervisor, Magu DSS / 1
Doris Mbata / Social Scientist / 1
Dr. Denna Michael / Research scientist / 1
DSS field workers / 11
Data entry clerks / 6

Funding sources

  • European Union
  • Netherlands Government
  • WHO
  • Welcome Trust
  • DFID
  • UNICEF
  • Community REACH
  • Global Fund

Collaborators

  • London School of Hygiene and Tropical medicine
  • ErasmusUniversity, Rotterdam

Publications

  1. Milly Marston, Jim Todd, Judith Glynn, Mark Urassa, Basia Zaba et. Estimating ‘net’ HIV-related mortality and the importance of background mortality rates. AIDS 2007.21(suppl. 6): S65-S71.

  1. Isingo R, Zaba B, Marston M, Ndege M, Mngara J, Mwita W, Wringe A, Beckles D, Changalucha J, Urassa M. Survival following HIV infection in the pre-ART era in a rural Tanzanian cohort.AIDS 2007.21(suppl. 6): S5-S13.

  1. Mwita W, Urassa M, Isingo R, Ndege M, Marston M, Slaymaker E, Mngara J,
Changalucha J, Boerma T, Zaba B. 2007. HIV prevalence and incidence in rural Tanzania: Results from 10 years of follow-up in an open cohort study. JAIDS 2007, Dec 15;46 (5):616-
623 18043316]
  1. G. Mshana, J. Wamoyi, J. Buzsa, J. Changalucha, S. Kaluvya, B. Zaba and M.Urassa. Barrier to uptake of ART in rural Tanzania. AIDS Patient Care &STDs, Vol. 20, No. 9, 2006

Minimum Dataset

No Dataset

SITE CONTACT DETAILS

Site Leader: Mark S. Urassa

NIMR Mwanza

P. O. Box 1462, Mwanza Tanzania

Tel: +255-028-2500399/2501230

Fax: +255-028-2500654

Email:

Web site: