NAME:Mohammed Tawfiq Numan

CURRICULUM VITAE: Mohammed .T. Numan

DATE: 8th December 2014

PRESENT TITLE: Associate Professor – March 2009 till now

Director, Pediatric Electrophysiology

Director, Dysautonomia Center/ Hermann Hospital

Department of Pediatrics- Cardiology

University of Texas- Houston

ADDRESS: The University of Texas McGovern Medical School Houston

Department of Pediatrics, Division of Pediatric Cardiology

6410 Fannin Street, Suite# 425

Houston, Texas. 77030

E mail:

CITIZENSHIP: Jordanian

Permanent Resident of USA

Under-graduate and Graduate Education:

March 1982-March 1990 MBBS King Faisal University,Dammam- Saudi Arabia

POSTGRADUATE TRAINING:

April 1990-December 1994 Pediatrics Residency, King Fahad University Hospital, Al-Khobar, Saudi Arabia.
January 1995-June 1996 Pediatrics Residency, University of Florida, Pensacola, Florida.
July 1996-June 1997Neonatology& Peri- natal Medicine Fellowship, State University of New York, Buffalo, New York.
July 1997-June 2000Pediatric Cardiology Fellowship, University of Florida, Gainesville, Florida.
October 1999-December 1999Congenital Heart interventional Catheterization training with Dr. Evan Zahn, Miami Children’s hospital, Miami, Florida.
July 2000-June 2001 Pediatric Cardiac Electrophysiology Fellowship, Medical University of South Carolina, Charleston, South Carolina.

ACADEMIC APPOINTMENTS:

1)Associate Professor of Pediatrics

Division of Pediatric Cardiology. Date: March 2009 till Current

Director, Pediatric Cardiac Electrophysiology

Department of Pediatrics

University of Texas & Health Science Center

Houston, Texas. 77030

2)Director, Dysautonomia Center/ Hermann Hospital

Hermann Children’s Hospital

Houston Medical Center Date: October 2011 till current

Houston, Texas 77030

3)Assistant Professor of Pediatrics Date: March 2008- March 2009

Department of Pediatrics

Weill Cornell Medical School-New York/Qatar

Doha, Qatar

4)Pediatric Residency Program Director

Department of Pediatrics Date: October 2002- July 2004

Hamad Hospital

Doha, Qatar

HOSPITAL APPOINTMENTS:

1)Senior Consultant of Pediatric Cardiology

Date: November 2001- March 2009

Department of Cardiology and Cardiac Surgery

Hamad Hospital

Doha, Qatar.

2)Director, Pediatric Cardiology

Date: 2004 till 2009

Department of Cardiology and Cardiac Surgery

Hamad Hospital

Doha, Qatar

3)Director, Cardiac Electrophysiology

Date: 2001 till 2009

Department of Cardiology and Cardiac Surgery

Hamad Hospital

Doha, Qatar

4)Director of Pediatric Residency Program

Date: 2002 till 2004.

Department of Pediatrics

Hamad Hospital

Doha, Qatar

5)Director of Quality Assurance Committee/Cardiology

Date: 2001 till 2004

Department of Cardiology and Cardiac Surgery

Hamad Hospital

Doha, Qatar

LICENSURE:

1)Jordan Medical Council, 1991

2)South Carolina Board of Medical Examiners, License# 21945, 2000-2002

3)Texas Medical Board, License# M7481, August 2007- Aug 2014

4)Qatar Medical License, 2001.

CERTIFICATION:

1)American Board of Pediatrics, October 1997. Recertification January 2010

2)American Board of Pediatrics, Sub-Board of Pediatric Cardiology,

August 2000.

3)Certificate of completion, Pediatric Cardiac Electrophysiology,

Medical University of South Carolina, July 2001.

PROFESSIONAL ORGANIZATIONSMembership:

1)Heart Rhythm Society ( Previously known NASPE) 2005-2006 and 2009- 2012

2)Cardiac Electrophysiology Society 2011-2012

3)American Autonomic Society 2012

4)Jordan Medical Association 1991-2005

5)Gulf Heart Association 2003-2009

HONORS AND AWARDS:

Best Publication of the year 2005 Award

Medical Research Center

Hamad Medical Corporation

Doha, Qatar

EDITORIAL POSITIONS:

Editorial board,The Journal of Tehran Heart Center, 2005 till current date.
Reviewer for: Qatar Medical Journal 2002- present.
Reviewer for : Heart Views journal, 2002
Reviewer for: Cardiology in the Young Journal.
Reviewer for: The Tohoko Journal of Experimental medicine.

SERVICE ON THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON COMMITTEES:

1)Member of “The Faculty Compensation Committee “from September 2011 till September 2014.

2)Medical Students admission committee: involved in interviewing medical students and recommendation of acceptance to the Medical school.

SERVICE ON UTMSH AFFILIATED HOSPITAL COMMITTEES:

Hermann Hospital Committee for Quality control and improvement of Pediatric Cardiology and Cardiovascular Program.

SPONSORSHIP OF POSTDOCTORAL FELLOWS:

1)Dr. Georgios Hartas: Pediatric Cardiology Fellow 2009-2011

2)Dr. EmmanouilTsounias: Pediatric cardiology Fellow 2009-2011

3)Dr. SrilathaAlapati: Pediatric Cardiology Fellow 2009-2011

4)Dr. Raj Sahu: Pediatric Cardiology Fellow 2009-2011

5)Dr. Ngozi Agu: Pediatric Cardiology Fellow 2009-2011

6)Dr. Henry Burkholder: Pediatric Cardiology Fellow 2010-2011

7)Dr. TharakanathaYarrabolu: Pediatric Cardiology Fellow 2010-2011

8)Dr. Arpan Doshi: Pediatric Cardiology fellow 2011-2014

9) Dr. UnnatiDoshi: Pediatric Cardiology fellow 2012- 2015

CURRENT TEACHING RESPONSIBILITIES:

Post Graduate Medical Education:

Primary teaching effort is currently directed towards Pediatric Cardiology fellows in training at the University of Texas/Hermann Children’s hospital. Shared in developing a curriculum in Pediatric cardiology, including informal discussions and didactic lectures (including: Action potential and cellular mechanisms of conduction, Trans Esophageal Electrophysiology studies, Principles of Pediatric EP testing and Tilt table testing) and emphasizing interpretive/analytical as well as manual skills.
Grand rounds to Pediatric faculty and residents at University of Texas/Hermann hospital:

1)Neuro-cardiogenic Syncope and Dysautonomia, November 8, 2011

2)Syncope in the young, September 2010

3)Emergency Management of Pediatric Arrhythmia, August 2009

Grand rounds and lectures to Adult Cardiology division at the University of Texas:

1)Grand round: Arrhythmia in adult congenital heart patients, January 2010

2)Lecture: Anatomy of Conduction system in Congenital Hearts, April 2010

3)Lecture: Tilt table testing for EP fellows: November 2009

4)Lecture: Junctional Ectopic Tachycardia for EP fellows May 2009

5)Lecture: Emergency treatment of Pediatric arrhythmia for EP fellows April 2009.

Lectures for Neonatology and Pediatric intensive care fellows at the department of Pediatrics, University of Texas & Health Science center:

1)Fetal and Neonatal Arrhythmia, September 2009.

2)Development of Embryonic Conduction system and its abnormalities (given in two sessions) July 2010.

2) Graduate Medical Education for medical students at the University of Texas:

Involved of serial lectures given every year to the 3rd and 4th year medical students at the University of Texas. Total of six lectures given in year 2010 and five lectures given in year 2009 for several groups (about 35 students each group). These lectures include Acquired Heart diseases in children, Cyanotic congenital heart diseases and Acyanotic congenital heart diseases.

Major Clinical Responsibilities and Interests:

Congenital Heart interventional catheterization:
Diagnostic hemodynamics and angiography
Device closures of ASD, PDA, Peri membranous and muscular VSD, Fenestrations and collaterals.
Angioplasties and stent placements of pulmonary arteries, Aorta, Vena cava and renal arteries.
Trans septal punctures and atrial Septostomies
Balloon aortic and pulmonary valvuloplasties
Cardiac Electrophysiology:
Non invasive diagnostic procedures including Signal averaged ECG, Holter Monitoring, exercise testing, Tilt table test, Event monitors and T wave micro voltage.
Trans Esophageal Electrophysiology testing
Implantation and management of Pace makers and ICD
Implantation of Bi ventricular Resynchronization devices
Performing invasive EP testing.
Conducting ablative therapy using RF energy, Cryo ablation and cooled tip ablation.
Autonomic Tilt table testing. Including evaluation of cardiac Stroke volume, Sympathetic/Parasympathetic tone, Heart rate and heart rate variability, Brain perfusion by Near Infra RedSpectrography (NIRS) and beat to beat BP during several positions of the patient during the test.

Performing and interpretation of Congenital heart Echocardiography including fetal Echo, Intra Cardiac Echo (ICE) and 3- Dimensional Echo

Current Clinical volume:

Annual Clinic visits: 1100 visits (twice weekly half day clinic)

Annual Invasive Procedures in the Cardiac catheterization Laboratory: 192 procedures.

Annual Autonomic evaluations and Tilt table testing: 220 procedures

Annual Non-invasive EP evaluation including Exercise test, Holter reporting, Event recorders, ECG’s, Pacemaker and ICD evaluations: 2100 tests

Annual Echocardiography and Intracardiac Echo readings: 900 studies.

CURRENT GRANT SUPPORT:

Project Title: Post-Approval study of Amplatzer Muscular Ventricular Septal defect Occluder device.

Primary Investigator at the University of Texas: Mohammed. T. Numan

Funding Agency: AGA Medical Corporation.

Award Period: April 2010 for 5 years

Amount of the grant: up to 75000$ per year.

PAST GRANT SUPPORT:

Co-investigator: Select Secure Medtronic lead Study for RV optimization, Grant from Medtronic Pacemaker Company. 2005
Co-investigator: Optimizing Cardiac Re Synchronization therapy using measured QRS duration. Grant by Guidant Pacemaker Company.

PUBLICATIONS:

Abstracts Presented at National and International Conferences:

1)Use of Self-Expandable stents in Congenital Heart Diseases in children and Adults, Medium to Long-term follow up.

Pediatric & Adult interventional cardiac symposium (PICS/AICS 2012)

Mohammed.T.Numan, Muhammad Dilawar and Duraisamy Balaguru

April 15-18, 2012. Chicago, IL.

2)Supra Ventricular Tachycardia significantly reduces Stroke volume and causes minimal reduction of Cardiac output: study of Pediatric Patients

Cardiac Electrophysiology Society Annual meeting. November 12, 2011. Orlando, Florida.

This abstract was published in Heart Rhythm Journal Vol 8, issue 11, 2011:1826

3)Cry ablation In Congenital Junctional Ectopic Tachycardia; Acute Efficacy And Safety Profile, And Long-term Clinical Outcome;

Tru Ho, Bharat Kantharia, Anne Dougherty and Mohammed Numan

Heart Rhythm Society 31st Annual scientific sessions

May 12th – 15th 2010. Denver, Colorado.

This meeting has 12000 attendees and it is the largest and most prestigious Electrophysiology meeting in the world. It is very competitive to get your scientific paper to be accepted for this meeting.

I was the senior author for the paper accepted in this meeting.

This article was presented by my fellow in training in this meeting. It discussed the feasibility and efficacy of Cryo (freezing) ablation for the rare arrhythmia of Junctional Ectopic tachycardia. This research impacts how we can approach this rare arrhythmia successfully without causing permanent damage to the heart as was prior management. This article was published in heart Rhythm Journal after this presentation.

4)Trans-Catheter Closure of Multi-Fenestrated Atrial Septal Defects: Comparison study of Helex vs Cribriform Devices

Mohammed T. Numan, Muhammad Dilawar, HowaidaElsaeed, Amal ElSisi

American College of Cardiology 59th Annual summit

March 14th- 16th 2010. Atlanta, Georgia.

This is the largest Cardiology meeting in the world, attended by 30000 attendees. Usually it is covered by national and international media to state the latest discoveries and recent advances in the field of Cardiology. Also it is very competitive to have your scientific paper to be presented in this meeting.

This article was presented as a podium presentation which carries higher importance than a poster presentation.

In this article I spoke about the challenges facing the interventional cardiologist to close multi-fenestrated (multiple holes) in the atrial septum (the partition between the upper two chambers of the heart). I share my experience in closure of such defects using two different brands of device. One of them has a special design of spiral wire covered by a special medical engineered material called HELEX and the other one is made of Nitinol metal (medically engineered metal). I discussed the long term results of the two devices in closure of these defects and evaluate the residual lesions in both which will help the audients in deciding which particular device to choose for specific morphology of the atrial septum.

5)Cryo ablation of congenital Junctional Ectopic Tachycardia with medium term follow up

Mohammed Numan, Mahmoud Sayed

5th World Congress of Pediatric Cardiology and Cardiac Surgery.

June 21st – 25th 2009. Cairns, Australia.

This meeting is the largest Pediatric Cardiology meeting happens once every four years and it alternates in location between the continents of the world.

6)CorTriatriatum sinister with persistent left superior vena cava

and dilated coronary sinus: A novel management approach

EmannouilTsanios, Numan MT, Gupta Monisha and Tsai Felix

5th World Congress of Pediatric Cardiology and Cardiac Surgery.

June 21st – 25th 2009. Cairns, Australia.

7)Tip Cooling Techniques Improve Success for Intra-atrial Reentrant Tachycardia

(lART) Ablation

Numan MT, Blaufox A, Knick B, Saul JP

North America Society of Pacing and Electrophysiology 22nd Annual Scientific session

May 2-5, 2001. Boston, Massachusetts.

This paper discussed our center experience at that time in Charleston, South Carolina with treating of very difficult arrhythmias happened in patient post operative cardiac surgeries. This arrhythmia happened because of the scars and the abnormal anatomy of those children born with heart defects. Previously we were using conventional energy of Radio-Frequency (Microwave) in trans- catheter ablation of the abnormal electrical connection inside the atrium called (intra- Atrial Reentrant tachycardia). In this study we showed that modification of this technology with cooling the catheter tip by fluids (Irrigated tip) improved the outcome of this procedure with long term success.

8)Respiration Effect on catheter stability during RF ablation

Mohammed T Numan, Andrew Blaufox, Barbara Knick, Philip Saul

3rd World Congress of Pediatric Cardiology and Cardiac surgery.

May 27-31, 2001. Toronto, Canada.

This paper talks about important clinical implication of the movement of the diaphragm (muscular partition between the chest and the abdomen) during respiration in obtaining stability of the Radio-Frequency catheter inside the heart. This is important to achieve adequate energy delivered at the abnormal electrical connection inside the heart to control the arrhythmia. We showed that stopping the breathing in anesthetized patients for one minute during the delivery of Radio-Frequency ablation improved the success without compromising the safety of the patient.

9)Echocardiographic Evaluation of the TGR(mRen2)27 TransgenicRat Reveals Severe Ventricular Hypertrophy and Pericardial Effusion:

Numan, Mohammed T; Byrne, Barry; GelbandCreg; Pachori, Alok;

Katovich, Michael; Ganten, Detlev;Fenario, Carlos; Raizada, Mohan

3rd World Congress of Pediatric Cardiology and Cardiac surgery.

May 27-31, 2001. Toronto, Canada

This paper discuss the animal model of hypertension for certain of certain rats and the useful tool of Echocardiogram in evaluating the changes of the heart including building fluid around the heart which may interfere with cardiac function. This was a basic science research of genetically engineered rats.

The third paper which I was the first author and it was a Podium presentation entitled:

10)Cooled tip catheter improved the outcome of Radio-Frequency ablation of intra-atrial reentrant tachycardia

Mohammed T Numan, Andrew Blaufox, Barbara Knick, Philip Saul

3rd World Congress of Pediatric Cardiology and Cardiac surgery.

May 27-31, 2001. Toronto, Canada

11)Sino-atrial reentrant tachycardia; an under-recognized clinical entity in infants with congenital heart disease

Andrew blaufox, Mohammed T Numan, Barbara Knick and Philip Saul

3rd World Congress of Pediatric Cardiology and Cardiac surgery.

May 27-31, 2001. Toronto, Canada

12)Cardiac Pathophysiology in a transgenic model of hypetension due to Elevated vascular impedance

Numan, Mohammed T; Byrne, Barry; GelbandCreg; Pachori, Alok;

Katovich, Michael; Ganten, Detlev;Fenario, Carlos; Raizada, Mohan

Southeastern Pediatric Cardiology Society Annual meeting

September 21-23, 2000. Charlotte, North Carolina.

This was an animal study involved genetically modified rats with hypertension. I did cannulation of those rats arteries in the abdomen during the anesthesia for those rats and measure the flow of blood in this vessel and the pressure changes, then extrapolate the vascular impedance (resistance) to the flow and showed their blood vessels caused elevated blood pressure. In the same time I did ultrasound of the heart and showed the ventricles of these rats hearts are hypertrophied (thickened) as a result of increase vascular impedance. This research helps in understanding the process of pathology involved in hypertension and how the stiff vessels in hypertensive subjects affect their heart by increasing the thickness.

13)Echocardiographic Evaluation of the TGR(mRen2)27 TransgenicRat Reveals Severe Ventricular Hypertrophy and Pericardial Effusion

Numan, Mohammed T; Byrne, Barry; GelbandCreg; Pachori, Alok;

Katovich, Michael; Ganten, Detlev; Fenario, Carlos; Raizada, Mohan

The American Pediatric Society and The Society for Pediatric Research 68th Annual Scientific sessions.

May 1-4,1999. San Francisco, California.

Refereed Original articles in Medical Journals:

1)El-Sisi A, Khella A, Numan M, Dilwar M, Bhat A, Soliman A: Linear Growth in Relation to the Circulating Concentration of Insulin-like Growth Factor-I and Free Thyroxine in Infants and Children with Congenital Cyanotic Heart Disease Before vs. After Surgical Intervention

J Trop Pediatr.2009 Oct;55(5):302-6.Epub ahead of print2009 Mar 1.

2)Numan M, El Sisi A, Tofeig M, Gendi S, Tohami T, El-Said HG.

Cribriform Amplatzer Device Closure of Fenestrated Atrial Septal Defects: Feasibility and Technical Aspects

Pediatric Cardiology Journal. 2008 May;29(3):530-5. Epub 2007 Nov 13

3)Dilawar M, Numan M, El-Sisi A, Gendi SM, Ahmad Z

Percutaneous Closure of Ventricular Septal Defect Associated with Tunnel-Shaped Aneurysm Using the Amplatzer Duct Occluder,

Pediatric Cardiology Journal.2008 Mar; 29(2):366-70

4. El-SisiAM, Gendi S, Dilawar M, Numan M.

Helex Septal Occluder: Feasibility Study of Closure of Atrial Septal Defect

Pediatric Cardiology Journal.2008 Jan;29(1):84-9

5.Mohammed T Numan, Sulafa KM Ali; Trans-catheter closure of large atrial septal defects in patients with Epstein’s malformation of the tricuspid valve: a report of two cases. Heart Views, 2007 volume 8, issue 3, page 109-111.

6. Amal El Sisi, Muhammed Dilawar, SalwaGendi, Mohammed Numan

Helex Septal Occluder: First Experience of Closure of Atrial Septal defect inQatar

Journal of the Saudi Heart Association. Vol 19, No 1.Jan 2007:36- 40

7. Ayman A. El-Menyar, Salwa M. Gendi, Mohammed T. Numan,

NoncompactionCardiomyopathy in the State of Qatar

Saudi Med J 2007;

8. El Sisi Amal, Numan Mohammed

Stenting Disconnected LPA in 2 Kg baby with Fallot Tetralogy, pulmonary atresia 4 days post RBT shunt.