REVISED 1/15/18
Late-Breaking Science
International Stroke Conference 2018
Opening Main Event, Wednesday, Jan. 24,2018
Embargo: 11:20 a.m. Pacific Time/2:20 p.m. Eastern Time, Jan. 24, 2018
LB 1Results of the DEFUSE 3 Study - Gregory Albers
LB2Tenecteplase Versus Alteplase Before Endovascular Thrombectomy (EXTEND-IA TNK): A Multicenter, Randomized, Controlled Trial -- Bruce Campbell
LB3Magnitude of Benefit of Endovascular Thrombectomy 6-24 Hours After Onset in Acute Ischemic Stroke Patients with Clinical-Core Mismatch – Jeffrey Saver
Thursday Main Event, Thursday, Jan. 25, 2018
Embargo: 11 a.m. Pacific Time/2 p.m. Eastern Time, Jan. 25, 21018
LB 4A Comparison of Direct Aspiration vs. Stent Retriever as a First Approach (COMPASS): A Randomized Trial – J Mocco
LB 5ARISE II Trial Result – Osama Zaidat
LB 6Subgroup Analyses of the DEFUSE 3 Study – Maarten Lansberg
LB 7The Effect of Rivaroxaban with Aspirin on Stroke Outcomes in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial– Mukul Sharma
LB 8Ticagrelor with Aspirin on Platelet Reactivity in Minor Stroke or Transient Ischemic Attack (PRINCE Trial)-Final Analysis – Yilong Wang
Late-Breaking Science Oral Abstracts Thursday, Jan. 25, 2018
(note varying embargo times in this session)
LB 9Alteplase for the Treatment of Acute Ischemic Stroke in Patients with Low NIHSS and Not Clearly-Disabling Deficits: Primary Results of the PRISMS Trial – Pooja Khatri
Embargo: 3:30 p.m. Pacific Time/6:30 p.m. Eastern Time, Jan. 25, 2018
LB 10Thrombolysis in Acute Ischemic Stroke Patients with Small Perfusion Lesions: Involvement of Corticospinal Tract Predicts Outcome -Ying Zhou
Embargo: 3:45 p.m. Pacific Time/ 6:45 p.m. Eastern Time, Thursday, Jan. 25, 2018
LB 11Benefit of Thrombectomy for Stroke with Clinical-Imaging Mismatch at 6-24 Hours in Dawn: Comparison of Patients Selected with Core Infarct Measured by MR-DWI vs CTP-rCBF – Cathy Sila
Embargo: 3:57 p.m. Pacific Time/ 6:57 p.m. Eastern Time, Thursday, Jan. 25, 2018
LB 12Modeled Impact of Bypass to an Endovascular-capable Center on Clinical Outcomes: An Analysis of the STRATIS registry– Nils Mueller
Embargo: 4:09 p.m. Pacific Time/ 7:09 p.m. Eastern Time, Thursday, Jan. 25, 2018
LB 13WEAVE™ Intracranial Stent Trial: Final Trial Results in 150 Consecutive Patients Treated On-Label – Michael Alexander
Embargo: 4:21 p.m. Pacific Time/ 7:21 p.m. Eastern Time, Thursday, Jan. 25, 2018
LB 14Two-year Safety and Clinical Outcomes in Chronic Ischemic Stroke Patients After Implantation of Modified Bone Marrow-derived Mesenchymal Stem Cells (sb623): A Phase 1/2a Study – Gary Steinberg
Embargo: 4:33 p.m. Pacific Time/ 7:33 p.m. Eastern Time, Thursday, Jan. 25, 2018
LB 1512 Month Functional Outcome After Intracerebral Implantation of Human Neural Stem Cells (PISCES-2) – Keith Muir
Embargo: 4:45 p.m. Pacific Time/ 7:45 p.m. Eastern Time, Thursday, Jan. 25, 2018
Closing Main Event Friday, Jan. 26, 2018
Embargo: 11:53 a.m. Pacific Time/2:53 p.m. Eastern Time, Jan. 26, 2018
LB 16Pharyngeal Electrical Stimulation for Early Decannulation in Tracheotomised Stroke Patients with Dysphagia (PHAST-TRAC): A Randomised, Single-blind, Pivotal, Superiority Trial – Philip Bath
LB 17DEFUSE 3 Angiographic Results Correlated with Clinical and Imaging Outcomes –Michael Marks
LB 18Final Results of the RHAPSODY Trial– Patrick Lyden
Late-Breaking Science Posters IWednesday, Jan. 24, 2018
Embargo:3 p.m.Pacific Time/6 p.m. Eastern Time, Jan. 24, 2018
LBP 1 –Effects of Canagliflozin on Stroke in the CANVAS Program –Richard Lindley
LBP 2 – Final Results of the RHAPSODY Trial –Patrick Lyden
LBP 3– Rivaroxaban for Prevention of Silent Stroke: Results of Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial MRI and Neurocognitive Deterioration Substudy (COMPASS MIND) –Mukul Sharma
LBP 4 – Boston Criteria Version 2.0 for Cerebral Amyloid Angiopathy: An International Collaboration -- Andreas Charidimou
LBP 6 –Preventing Ischemic Cerebrovascular Events in High-risk Patients with Acute Non-disabling Cerebrovascular Events Using Remote Ischemic Conditioning: A Single-arm, Open-label, Multi-center Phase IIa Futility Study –Shimeng Liu
LBP 7 –Emergent Angioplasty or Stenting After Thrombectomy in Patients with Underlying Intracranial Atherosclerotic Stenosis – Chuanjie Wu
LBP 8 –A Cluster Randomized Trial of a Multifaceted Intervention to Improve AcuteIschemic Stroke Care in China - Yilong Wang
LBP 9 –Improving Transitions in Acute Stroke Patients After They Return Home: Results of the Michigan Stroke Transitions Trial (MISTT)–Mathew J Reeves
LBP 10 –Intima-Medial Thickness Sub-Study of the PreventIon of CArdiovascular Events in iSchemic Stroke Patients with High Risk of Cerebral hemOrrhage Study - Woo-Keun Seo
LBP 11 –Preclinical Development of a Human Neural Stem Cell Extracellular Vesicle Therapy in Murine and Porcine Stroke Models– Emily W Baker
LBP 12 –Safety and Feasibility of Remote Ischemic Conditioning in Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy: A Pilot Study–Wenbo Zhao
LBP 13–Reversal of Dabigatran Anticoagulation with Idarucizumab in Patients with Intracranial Hemorrhage: Subanalysis of RE-VERSE AD –Thorsten Steiner
LBP 14 –Effect of a Nationwide Stroke Centers Network on Key Processes of Evidence-based Acute Stroke Care in China –Feng Yan
LBP 15 –ADAPT Reperfusion with ACE64 and ACE68 is Safe and Effectivein Large Vessel Occlusions of the Anterior Circulation. The PROMISE RegistryResults –Peter Schramm
LBP 16 –S100A1, a Calcium Binding Protein and Novel Regulator of Endothelial Nitric Oxide Synthase (eNOS or NOS3), in Ischemic Stroke –Sumbul Fatima
LBP 17 –Global Variation and Burden of Hemorrhagic Stroke –Steven O'Donnell
LBP 18–Effectiveness of the Stroke Riskometer App for Primary Stroke Prevention: A Pilot RCT – Rita V Krishnamurthi
LBP 19 –THRIVES: Randomized Controlled Trial of a Multipronged Intervention to Improve Blood Pressure Control Among Stroke Survivors –Bruce Ovbiagele
LBP 20–Outcome Impact of Day-1 Extracranial ICA Patency in Stroke Patients with Tandem Occlusions - Thomas Personnic
LBP 21 –TrkB Receptor Activation and Improvements in Recognition and Spatial Memory in Neonatal Mice Following Perinatal HI in an Estrogen Receptor Dependent Way–Pelin Cengiz
LBP 22 –Severity Distributions in Patients with Low NIHSS Ischemic Stroke: A Comparative Analysis of PRISMS and MaRISS –Negar Asdaghi
LBP 23–Targeting PI3-Kinase Gamma for Thrombolytic Therapy in a Rat Model of Embolic Stroke– Adam Y Xiao
LBP 24 –LBP24Intracerebral hemorrhage produces differential expression of genes in peripheral blood – Boryana Stamova
LBP 26 –Development and Validation of Clinical Prediction Rules to Classify Type of Stroke at Prehospital –Uchida Kazutaka
LBP 27 –Fully Automated Insonation of the MCA Using a Robotically Controlled Transcranial Doppler Ultrasound Probe –Robert Hamilton
LBP 28–Electronic Decision Support for Improvement of Contemporary Therapy for Stroke prevention (EDICTS) –Seemant Chaturvedi
LBP 29 – Effect of Penetrating Arteries Atherosclerosis Detected by 7T MRI in Patients with Deep Isolated Ischemic Stroke –Haiqiang Qin
LBP 30 –Longitudinal Gene Expression Profiling Identifies Immune Components as a Predominant Molecular Signature Across Post-stroke Stages in Mouse –Wen Fury
LBP 31 –Preventing Cognitive Decline and Dementia from Cerebral Small Vessel Disease: The LACI-1 Trial –Joanna M Wardlaw
LBP 32 –A Common Data Language forClinical Research Studies: Review and Updates to the National Institute of Neurological Disorders and Stroke and National Library of Medicine Unruptured Cerebral Aneurysms and Subarachnoid Hemorrhage Common Data Elements Version 1.0 Recommendations –Muniza Sheikh
LBP 33–Accuracy and Validity of Intravascular Ultrasound as a Clinical Adjunct for Cerebral Venous Sinus Stenosis –Feng Yan
LBP 34 –Time and Severity Dependent EMS Stroke Triage in King County, Washington: A Population Based Study – David L Tirschwell