SOPHIE DESMONDE-PHILLIPS, Phd

Sophie Desmonde-Phillips
Curriculum Vitae / 1

SOPHIE DESMONDE-PHILLIPS, PhD

Inserm U897, HIV, Cancer and Global Health in resource-limited settings

Bordeaux School of Public Health, University of Bordeaux, France

Massachussetts General Hospital, Medical Practice Evaluation Center, Boston USA

Education

Doctorate of Philosophy, Public Health, University of Bordeaux, France2013

Master of Science, Epidemiology & Biostatistics, University of Bordeaux, France2010

Master of Public Health, University of Aix-Marseille II, France2009

Bachelor of Science, Biology, University of Caen-Basse-Normandie, France2008

Awards, grants and training

2-year Young Investigator grant, Sidaction, France2015

Methods for decision making in medicine, Harvard School of Public Health 2012

Doctoral fellowship (3 years), French Ministry of Research and Higher Education, France 2010

Methods for database management in medicine, Bordeaux School of Public Health 2007

Research experience

Medical Practice Evaluation Center 2015 - present

Massachussetts General Hospital, Boston, USA

Post-doctoral fellowship under the supervision of Dr Andrea Ciaranello

Current projects include the development of a simulation model of HIV infection in perinatally HIV-infected children in resource-limited settings.

Inserm U897, HIV, Cancer and Global Health in resource-limited settings 2014 - 2015

Bordeaux School of Public Health, University of Bordeaux, France

Postdoctoral research under the supervision of DrValeriane Leroy

Improving access to early infant diagnosis and improving outcomes for HIV-infected children in Côte d’Ivoire and immune response to antiretroviral therapy in HIV-infected children and duration of first-line antiretroviral regimens in West Africa

Institute of Child Health, May 2014

Univeristy College London, London, United Kingdom

Postdoctoral research under the supervision of Dr Robin Callard

Immune response to antiretroviral therapy in HIV-infected children with chronic lung disease in India

Inserm U897, HIV, Cancer and Global Health in resource-limited settings 2010- 2013

Bordeaux School of Public Health, University of Bordeaux, France

Doctoral thesis research conducted under the supervision of DrValeriane Leroy

Mortality, morbidity and healthcare resource utilization in HIV-infected children before and after

antiretroviral therapy initiation in West Africa

Medical Practice Evaluation Center Jun-Sept 2012

Massachussetts General Hospital, Boston, USA

Doctoral internship under the supervision of Dr Andrea Ciaranello

Participating in model-based clinical projections and cost-effectiveness analyses,

Programme PAC-CI, Feb-May 2010

Abidjan, Côte d’Ivoire

Master’s thesis research conducted under the supervision of DrValeriane Leroy

Collecting data from two principal HIV clinics in Abidjan and analysing and interpreting data

University teachingexperience

Lecturer, Bordeaux Anesthesia Nursing School,University Hospital of Bordeaux, France

Critical analyses and writing of scientific articles” for students in their final year (2014-present)

Sessional lecturer, Department of Mathematics and modeling,University of Bordeaux, France

“Introduction in Epidemiology” for second-year undergraduate students (2011- present)

Tutor, Bordeaux school of Public Health, University of Bordeaux, France

“Methods in Epidemiology” online training (2010-present)

Teaching Assistant, Bordeaux school of Public Health, University of Bordeaux, France

“Principles of Epidemiology” for graduate students (2012-2013)

“Medical Computer Science” for second-year medical student (2012-2013)

Mentoring experience

Group project tutoring (Master in Public Health)

Building a database for costs of HIV care in HIV-infected children in the context of the MONOD ANRS 12206 trial (2015)

Masters in Science, International Health:

Review of routine care offered to HIV-infected children in Cameroun: KAP survey among healthcare workers (2014)
Effect of cotrimoxazole prophylaxis on the incidence of malaria in HIV-infected children in 2012, in Abidjan, Côte d’Ivoire: a prospective cohort study (2012)

Master in Science, Epidemiology:

Effect of age at ART initiation on catch-up growth within the first 24 months among HIV-infected children in the IeDEA West African paediatric cohort (2013)

Publications

Jesson J, Koumakpaï S, Diagne N., Amorissani-Folquet M, Kouéta F, Aka A, Lawson-Evi K, Dicko F,Kouakou K, Pety T, Renner L, Eboua T, Coffié P,Desmonde S, Leroy V, for the paediatric WADA IeDEA collaboration. Effect of age at ART initiation on catch-up growth within the first 24 months among HIV-infected children in the IeDEA West African paediatric cohort.Ped Inf Dis J2015: in press

Desmonde S, Dicko F, Koueta F, Eboua T, Balestre E, Amani-Bosse C, Aka AE, Lawson-Evi K, Amorissani-Folquet M, Kouakou K, Koumakpai S, Renner L, SignateSy H, Leroy V. Association between age at antiretroviral therapy initiation and 24-month immune response in HIV-infected children in the IeDEApaediatric West African Cohort. AIDS 2014.Epub 2014/05/09.

F. Dicko, S. Desmonde S.Koumakpai,H. Dior-Mbodj, F. Kouéta, N. Baeta, N. Koné, J. Akakpo, H. SignateSy, D. Ye, L. Renner, C. Lewdenand V. Leroy for the PaediatricIeDEA West Africa Working Group. Reasons for hospitalisation in HIV-infected children in West Africa. J Int AIDS Soc.2014 Apr 22;17(1):18818

Desmonde S, Essanin JB, Aka AE, Messou E, Amorissani-Folquet M, Rondeau V, Ciaranello A, Leroy V. Morbidity and Health care Resource Utilization in HIV-Infected Children After Antiretroviral Therapy Initiation in Côte d'Ivoire, 2004-2009. J Acquir Immune DeficSyndr. 2014 Mar 1;65(3):e95-e103.

Ciaranello AL, Morris BL, Walensky RP, Weinstein MC, Ayaya S, Doherty K, Leroy V, Hou T, Desmonde S, Lu Z, Noubary F, Patel K, Ramirez-Avila L, Losina E, Seage III GR, Freedberg KA. Validation and Calibration of a Computer Simulation Model of Pediatric HIV Infection.PLoS One. 2013 Dec 13;8(12):e83389.

Yapo V, d'Aquin Toni T, Desmonde S, Amani-Bosse C, Oga M, Lenaud S, Menan H, Timité-Konan M, Leroy V, Rouzioux C. Evaluation of dried blood spot diagnosis using HIV1-DNA and HIV1-RNA Biocentric assays in infants in Abidjan, Côte d'Ivoire. The Pedi-Test DBS ANRS 12183 Study.J Virol Methods. 2013Nov;193(2):439-45.

Desmonde S, Coffie PA, Aka EA, Amani-Bosse C, Messou E, Dabis F, Ciaranello A, Leroy V. Health care resource utilization in untreated HIV-infected children in a pediatric programme, Abidjan, Côte d'Ivoire, 2004-2009. J Acquir Immune DeficSyndr. 2013 Jan 1;62(1):e14-21.

Desmonde S, Coffie P, Aka E, Amani-Bosse C, Messou E, Dabis F, Alioum A, Ciaranello A, Leroy V. Severe morbidity and mortality in untreated HIV-infected children in a paediatric care programme in Abidjan, Côte d'Ivoire, 2004-2009. BMC Infect Dis. 2011 Jun 23;11:182.

Manuscripts in preparation / revision

Desmonde S, F, Eboua, Malateste K, Dicko F, Ekouevi DK, Ngbeché S, Koueta F, SignateSy H, Renner L, Koumakpai Sand Leroy V. Determinants of durability of first-line ART regimen and time from first-line failure to second-line ART initiation. The IeDEApaediatric West African Database (pWADA).AIDS. In revision

MounkaïlaHarouna A, Amorissani-Folquet M, Eboua F, Desmonde S, Aka E, KouakouK, Kouacou B, Malateste M, Bosse-Amani C, Coffie P and Leroy V. Effect of cotrimoxazole prophylaxis on the incidence of malaria in HIV-infected children in 2012, in Abidjan, Côte d’Ivoire: a prospective cohort study. BMC Infectious Diseases. In revision

NguenaNguefack H, Gwet H, Desmonde S, OuweMissiOukem-Boyer O, Nkenfou C, Tejiokem M, Tchendjou P, Domkam I, Leroy V , Alioum A. Estimating Mother-to-child HIV transmission rates in Cameroon in 2011: a computer simulation approach. Bull WHO. In preparation

Invited talks

Desmonde S, Essanin JB, Amorissani-Folquet M, Aka EA, Messou E, Rondeau V, Ciaranello A, Leroy V. Severe morbidity in HIV-infected children on antiretroviral therapy in a pediatric programme, Abidjan, Cote d'Ivoire, 2004-2009. 4e Rencontres Scientifiques du Réseau Doctoral de l’EHESP, Paris, 2013

Desmonde S,Dicko F, Koueta F, Malateste K, Kouakou K, Renner L, Aka EA, SignatéSy H, Leroy V. 24-month immune recovery according to age at initiation of antiretroviral therapy in the IeDEApaediatric West African Cohort (pWADA). 3e Rencontres Scientifiques du Réseau Doctoral de l’EHESP, Paris, 2012

Desmonde S, Coffie PA, Aka EA, Amani-Bosse C, Messou E, Dabis F, Ciaranello A, Leroy V. Severe morbidity and healthcare resource utilisation in untreated HIV-infected children in Abidjan, Cote d’Ivoire, 2004-2009. Journées Scientifiques du Programme PACCI – site ANRS d’Abidjan 2012, Abidjan, Côte d’Ivoire

Desmonde S, Coffie PA, Aka EA, Amani-Bosse C, Messou E, Dabis F, Ciaranello A, Leroy V. Severe morbidity and mortality in untreated HIV-infected children in a paediatric care programme in Abidjan, Cote d’Ivoire, 2004-2009. 2e Rencontres Scientifiques du Réseau Doctoral de l’EHESP, Paris, 2011

Poster presentations

Desmonde S,Dicko F, Koueta F, Malateste K, Kouakou K, Renner L, Aka EA, SignatéSy H, F. Dabis,Leroy V. Patterns of CD4 reconstitution in HIV-infected children after initiation of antiretroviral therapy in the IeDEApaediatric West African Cohort (pWADA). XXII Conference on AIDS.Melbourne, Australia, 2014

Dicko F, Desmonde S, Koumakpai S, Dior-Mbojd H, Koueta F, Baeta N, Kone N, Akakpo J, SignateSy H, Ye D, Renner L, Lewden C, Leroy V. Reasons for hospitalisation in HIV-infected children in West Africa. 17th International Conference on AIDS and STIs in Africa, Cape Town, South Africa, 2013

Mounkaïla-Harouna A, Amorissani-Folquet M, Eboua F, Desmonde S, Aka EA, Kouadio K, Kouacou B, Amani-Bosse C,Coffie P, Leroy V. Incidence of Malaria in HIV+ Children on Pediatric ART: Côte d’Ivoire, International Epidemiologic Databases to Evaluate AIDS, 2004-2009. 20th Conference on Retroviruses and Opportunistic Infections, Atlanta, USA, 2013

Desmonde S,Dicko F, Koueta F, Malateste K, Kouakou K, Renner L, Aka EA, SignatéSy H, Leroy V. 24-month immune recovery according to age at initiation of antiretroviral therapy in the IeDEApaediatric West African Cohort (pWADA). 4th HIV Pediatrics Workshop, Washington DC, USA, 2012

Desmonde S,Dicko F, Koueta F, Malateste K, Kouakou K, Renner L, Aka EA, SignatéSy H, Leroy V. Modelling 24-month immune recovery according to age and CD4 percent at initiation of antiretroviral therapy in the IeDEApaediatric West African Cohort (pWADA). 16th International Workshop on Observational HIV Databases. Athens, Greece, 2012

Malateste K, Dicko F, Desmonde S, Koueta F, Eboua T, Renner L, Aka EA, SignatéSy H, Leroy V, Alioum A. Estimating unbiased mortality risks in paediatric antiretroviral cohorts: do we need to use a Kaplan-Meier method or a competing risks method? The IeDEA West Africa Paediatric Collaboration (pWADA). 16th International Workshop on Observational HIV Databases. Athens, Greece, 2012

Yapo V, Toni TA, Desmonde S, Amani-Bosse C, Oga M, Lenaud S, Menan H Timité-Konan M, Leroy V, Rouzioux C. Evaluation of dried blood spot diagnosis using HIV1-DNA and HIV1-RNA Biocentric assays in infants in Abidjan, Côte d'Ivoire. The Pedi-Test DBS ANRS 12183 Study 16th International Conference on AIDS and STIs in Africa, Addis Ababa, Ethiopia 2011

Desmonde S, Coffie P, Aka EA, Amani-Bosse C, Messou E, Dabis F, Ciaranello A, Leroy V. Severe morbidity and healthcare resource utilisation in untreated HIV-infected children in Abidjan, Cote d’Ivoire, 2004-2009. 6th IAS Conference on HIV pathogenesis, treatment and prevention, Rome, Italy, 2011

Desmonde S, Coffie P, Aka EA, Amani-Bosse C, Messou E, Dabis F, Ciaranello A, Leroy V. Severe morbidity and mortality in untreated HIV-infected children in a paediatric care programme in Abidjan, Cote d’Ivoire, 2004-2009. 18th Conference on Retroviruses and Opportunistic Infections, Boston, USA, 2011.(Young Investigator Award)

Malateste K, Aka EA,Desmonde S, Amani-Bosse C, Dabis F, Toure P, Alioum A, Tanoh E, Leroy V. Predictive Value of CD4 count for the 12-month risk of death among untreated HIV-1+ children: Abidjan, Côte d’Ivoire. 18th Conference on Retroviruses and Opportunistic Infections, Boston, USA, 2011