Amendment I (3-2-12):

This amendment reflects changes to the FOA noted in red text on the following pages3, 4, 6, 7, and 8.

Major Changes to the FOA:

1) The number of awards was reduced from four to two.

2) The total amount of funds that NCIPC intends to commit to this FOA in FY 2012 was changed from $1,600,000 to $800,000

3) The application due date was changed from March 16, 2012 to April 5, 2012

4) Research aimed specifically at preventing youth violence was removed as a priority area in the FOA due to budget reductions. Applications for dissemination/implementation research on youth violence or efficacy/effectiveness studies designed to prevent youth violence will not be accepted or awarded under this FOA.

Table of Contents

Part1. Overview Information
Part2. Full Text of the Announcement

Section I. Funding Opportunity Description
Section II. Award Information
Section III. Eligibility Information
Section IV. Application and Submission Information
SectionV. Application Review Information
Section VI. Award Administration Information
Section VII. Agency Contacts
Section VIII. Other Information

Part 1. Overview Information

Participating Organization(s)
/ Centers for Disease Control and Prevention (CDC)
Components of Participating Organizations
/ National Center for Injury Prevention and Control (NCIPC)
Funding Opportunity Title
/ Research Grants for Preventing Violence and Violence Related Injury
Mechanism of Support
/ R01 Research Project Grant
Announcement Type
/ New
Funding Opportunity Announcement (FOA) Number
/ RFA-CE-12-002
Catalog of Federal Domestics Assistance (CFDA) Number(s)
/ 93.136, Injury Prevention and Control Research and State and Community Based Programs
Category of Funding Activity
/ Health
FOA Purpose
/ The purposes of the NCIPC extramural violence prevention research program are to:
  • Build the scientific base for the prevention of violence by helping to expand and advance our understanding of the primary prevention of interpersonal and self-directed violence.
  • Encourage professionals from a wide spectrum of disciplines of epidemiology, behavioral and social sciences, medicine, biostatistics, public health, health economics, law, and criminal justice to perform research in order to prevent violence more effectively.
  • Encourage investigators to propose research that involves the development and testing of primary prevention strategies as well as research on methods to enhance the adoption and maintenance of effective strategies among individuals, organizations, or communities.
NCIPC is soliciting investigator-initiated research that will expand and advance the understanding of how best to disseminate and implement evidence-based strategies, programs, and policies. NCIPC is also soliciting research in areas where less is known about what works to prevent violence such as teen dating violence, intimate partner violence, sexual violence, and suicidal behavior.

Key Dates

Publication Date
/ To receive notification of any changes to RFA-CE-12-002 return to the synopsis page of this announcement at and click on the “Send Me Change Notification Emails” link An email address is needed for this service.
Letter of Intent Due Date
/ February 16, 2012
Application Due Date
/ April 5, 2012,by 5:00 PM Eastern Time.
On-time submission requires that electronic applications be error-free and made available to CDC for processing from eRA Commons on or before the deadline date. Applications must be submitted to and validated successfully by Grants.gov/eRA Commons no later than 5:00 PM Eastern Time.Note:HHS/CDC grant submission procedures do not provide a period of time beyond the application due date to correct any error or warning notices of noncompliance with application instructions that are identified by Grants.gov or eRA systems (i.e., error correction window).
Scientific Merit Review
/ May, 2012
Secondary Review
/ June, 2012
Start Date
/ September, 2012

Expiration Date

/ April 6, 2012

Due Dates for E.O. 12372

/ Executive Order 12372 does not apply to this program.

Required Application Instructions

It is critical that applicants follow the instructions in theSF 424 (R&R) Application Guideexcept where instructed to do otherwise (in this FOA or in a Notice from the NIH Guide for Grants and Contracts). Conformance toall requirements (both in the Application Guide and the FOA) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions.

Note: The Research Strategy component of the Research Plan is limited to25 pages.

Applicationsthat do not comply with these instructions may be delayed or not accepted for review.

Telecommunications for the Hearing Impaired: TTY 1-888-232-6348

Part 2. Full Text

Section I. Funding Opportunity Description

Statutory Authority

Section 301 (a) [42 U.S.C. 241(a)] of the Public Health Service Act, and section 391 (a)[42 U.S.C. 280 b(a)] of the Public Service Health Act, as amended.

Background

Violence is a significant public health problem in the United States. Each year, more than 50,000 people in the United States die as a result of violence and more than 2,000,000 are treated in emergency departments for a violence-related injury. The number of violence-related deaths and injuries tell only part of the story. Violence can lead to other significant mental and physical health consequences such as depression and anxiety, pregnancy complications, and even chronic diseases such as diabetes and heart disease. Violence also erodes the sense of safety and security so essential to the well-being of families and significantly impacts communities by reducing productivity, decreasing property values, and disrupting social services.

The National Center for Injury Prevention and Control is committed to stopping violence before it begins (i.e., primary prevention). The Center’s work in violence prevention involves:

  • Monitoring violence-related behaviors, injuries, and deaths
  • Conducting research on the factors that put people at risk or protect them from violence
  • Developing and evaluating the effectiveness of violence prevention strategies, programs, and policies
  • Helping state and local partners plan, implement, and evaluate prevention programs
  • Conducting research on the dissemination and implementation of evidence-based prevention strategies, programs, and policies and ensuring their widespread adoption

Purpose

The purposes of the NCIPC extramural violence prevention research program are to:

  • Build the scientific base for the prevention of violence by helping to expand and advance our understanding of the primary prevention of interpersonal and self-directed violence.
  • Encourage professionals from a wide spectrum of disciplines of epidemiology, behavioral and social sciences, medicine, biostatistics, public health, health economics, law, and criminal justice to perform research in order to prevent violence more effectively.
  • Encourage investigators to propose research that involves the development and testing of primary prevention strategies as well as research on methods to enhance the adoption and maintenance of effective strategies among individuals, organizations, or communities.

This program addresses the “Healthy People 2020” focus area(s) of injury and violence prevention. For more information see It is also in alignment with NCIPC’s performance goal to conduct a targeted program of research to prevent injuries and violence, and reduce their consequences. For more information on the CDC Injury Research Agenda see

Research Objectives

NCIPC is soliciting investigator-initiated research that will help expand and advance our understanding of how best to disseminate and implement evidence-based strategies, programs, and policies. NCIPC is also soliciting investigator-initiated research in areas where we know less about what works to prevent violence such as teen dating violence, intimate partner violence, sexual violence, and suicidal behavior.1 The following research objectives are the focus of this announcement:

  1. Dissemination/Implementation Research

Note:Dissemination/Implementation research specifically aimed at preventing youth violence was removed as a priority area in this section due to budget reductions in youth violence. Applications for dissemination/implementation research on youth violence will not be accepted or awarded under this FOA.

Conduct studies aimed at identifying and evaluating efficient and effective methods for the dissemination and implementation of evidence-based strategies, programs or policies to prevent child maltreatment. This research is intended to bridge the gap between prevention research and everyday practice by building a knowledge base about how evidence-based violence prevention information and strategies are disseminated, translated and integrated for use by communities and policy makers. Examples of such studies include: (a) examining the optimal ways to synthesize, translate, and package effective prevention approaches; (b) examining ways to build individual and organizational capacities to use effective approaches (i.e., understanding the type and quality of technical assistance – training, coaching, monitoring – necessary to support effective implementation); (c) understanding how individual, organizational and community characteristics influence the adoption and effective use of empirically-supported child maltreatment prevention approaches; and (d) once an effective approach is adopted, understanding the effects of implementing the program, policy, or practice as originally developed (i.e., with “fidelity”), as opposed to changing the content or delivery format (i.e., “adapting”). While adaptation occurs with great frequency in the practice field, we know very little about the kinds of modifications that are likely to diminish or increase an intervention’s effectiveness.

Evidence-based strategies, programs or policies are defined as those for which there is evidence of effectiveness in reducing perpetration of or victimization from child maltreatment based on systematic reviews of the field or two or more well designed experimental studies (randomized controlled trials) or quasi-experimental studies.

  1. Efficacy/Effectiveness Research:

Note:Efficacy/Effectiveness research specifically aimed at preventing youth violence (e) was removed as a priority area in this section due to budget reductions in youth violence. Applications for efficacy/effectiveness studies designed to prevent youth violence will not be accepted or awarded under this FOA.

Evaluate the efficacy, effectiveness, and cost effectiveness of primary prevention strategies, programs, and policies to prevent the perpetration of interpersonal violence or suicidal behavior. These strategies, programs or policies can be targeted universally or at selected or high-risk populations (i.e., populations that have one or more risk factors that place them at heightened risk for initial perpetration of violence or suicidal behavior), but cannot be targeted at individuals who have already engaged in the perpetration of violence or suicidal behavior. Funds are available to conduct such studies aimed at preventing the perpetration of child maltreatment, sexual violence, intimate partner violence, orsuicidal behavior.

(a)In the area of child maltreatment, there is interest in studies that assess the extent to which primary prevention parenting programs can be implemented in communities to reduce the incidence of child maltreatment and promote Safe, Stable, and Nurturing Relationships (SSNRs)2 to achieve reductions in child maltreatment. There is also interest in studies that assess the efficacy/effectiveness of other primary prevention strategies to prevent child maltreatment and promote SSNRs (e.g., organizational policies). There is also interest in evaluating the development and delivery of training strategies for childcare professionals that are geared toward building their capacity and skills to support parents in fostering safe, stable, and nurturing relationships for their children and for integrating policies and practices into childcare settings that promote SSNRs and create supportive social environments for children.

(b)In the area of sexual violence, there is particular interest in assessing the impact of efforts to influence bystanders and peer groups (i.e., efforts to stop sexual violence by influencing the norms among groups/bystanders); approaches that engage men and boys in the prevention of sexual violence; the use of action and asset models to build and support youth to challenge current norms or behaviors that support sexual violence; and the impact of policies or organizational/community level practices that might impact upon or contribute to either decreasing risk factors or increasing protective factors for sexual violence.

(c)Within the context of teen dating and intimate partner violence, there is interest in assessing the efficacy/effectiveness of primary prevention strategies aimed at preventing the initial perpetration of partner violence and promoting respectful, nonviolent relationships.3 Because multiple individual, relationship, community and societal factors and their interactions might influence the perpetration of partner violence, a critical need exists for research to evaluate primary prevention strategies aimed at promoting respectful, nonviolent relationships at these various levels of the social ecology. There is also interest in studies that assess whether primary prevention strategies aimed at preventing physical violence within an intimate partner relationship also prevent sexual violence within an intimate partner relationship.

(d)In the area of suicidal behavior, there is interest in efficacy/effectiveness studies of existing strategies (e.g., school-based programs) to prevent suicidal behavior as well as other possible approaches (e.g., strategies aimed at enhancing individual, family, and community connectedness4; community-level efforts to reduce social isolation and stigma associated with seeking help for personal crises; strategies aimed at reducing other environmental and community-level risk factors; programs and policies to reach groups at high risk). There is also interest in studies to determine whether evidence-based programs for other forms of violence can also prevent suicidal behavior.

References:

  1. National Center for Injury Prevention and Control. CDC Injury Research Agenda, 2009-2018. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention; 2009. Available at:
  2. Centers for Disease Control and Prevention. Strategic direction for child maltreatment prevention: Preventing child maltreatment through the promotion of Safe, Stable, and Nurturing Relationships between children and their caregivers. Available at:
  3. Centers for Disease Control and Prevention. Strategic direction for intimate partner violence: Promoting respectful, nonviolent intimate partner relationships through individual, community and societal change. Available at:
  4. Centers for Disease Control and Prevention. Strategic direction for the prevention of suicidal behavior: Promoting individual, family and community connectedness to prevent suicidal behavior. Available at:

Section II. Award Information

Funding Instrument

/ Grant

Application Types Allowed

/ New
The OER Glossaryand the SF 424 (R&R) Application Guide provide details on these application types.

Funds Available and Anticipated Number of Awards

/ NCIPC intends to commit approximately $800,000 in FY 2012 to fund up to two applications.
Awards issued under this FOA are contingent on the availability of funds and submission of a sufficient number of meritorious applications.

Ceiling and Floor of Individual Award Range

/ The maximum award amount will be $400,000 for the first 12 month budget period. This includes both direct and indirect costs. An applicant may request a project period of up to three years. The maximum total project funding amount is $1,200,000 (including both direct and indirect costs), with a maximum of $400,000 per year.

Project Period Length

/ Three years
Throughout the project period, CDC's commitment to continuation of awards will be conditional on the availability of funds, evidence of satisfactory progress by the recipient (as documented in required reports), and the determination that continued funding is in the best interest of the Federal government.

HHS/CDC grants policies as described in the HHS Grants Policy Statementwill apply to the applications submitted and awards made in response to this FOA.

Section III. Eligibility Information

1. Eligible Applicants

Eligible Organizations

Higher Education Institutions:

  • Public/State Controlled Institutions of Higher Education
  • Private Institutions of Higher Education

The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education:

  • Hispanic-serving Institutions
  • Historically Black Colleges and Universities (HBCUs)
  • Tribally Controlled Colleges and Universities (TCCUs)
  • Alaska Native and Native Hawaiian Serving Institutions

Nonprofits Other Than Institutions of Higher Education

  • Nonprofits (Other than Institutions of Higher Education)

For Profit Organizations

  • Small Businesses
  • For-Profit Organizations (Other than Small Businesses)

Governments

  • State Governments
  • County Governments
  • City or Township Governments
  • Special District Governments
  • Indian/Native American Tribal Governments (Federally Recognized)
  • Indian/Native American Tribal Governments (Other than Federally Recognized)
  • Eligible Agencies of the Federal Government
  • U.S. Territory or Possession

Other

  • Independent School Districts
  • Public Housing Authorities/Indian Housing Authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Faith-based or Community-based Organizations
  • Regional Organizations
  • Bona Fide Agents

A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with "Other Attachment Forms" when submitting via

Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Foreign (non-U.S.) components of U.S. Organizations are notallowed.

Required Registrations

Applicant organizations must complete the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. Applicants must have a valid Dun and Bradstreet Universal Numbering System (DUNS) number in order to begin each of the following registrations.

  • Central Contractor Registration (CCR) – must maintain current registration in CCR.
  • Grants.gov
  • eRA Commons

All Program Directors/Principal Investigators (PD/PIs) must also work with their institutional officials to register with the eRA Commons or ensure their existing eRA Commons account is affiliated with the eRA Commons account of the applicant organization.
All registrations must be successfully completed and active before the application due date. Applicant organizations are strongly encouraged to start the registration process at least four (4) weeks prior to the application due date.