Retreat Program

Retreat Program

Friday, September 26, 2014

Mentoring, Education & Training Panel – The Grand Salon
9:00 a.m. – Noon
(Closed Session) / Mentoring Presentations
Lari Wenzel, PhD
Noon – 1:00 p.m. / Lunch @ the Atrium
Session I – The Grand Salon
1:00 – 1:05 p.m. / Welcome & Introductory Remarks
Richard A. Van Etten, MD, PhD
1:05 – 1:35 p.m. / High Impact Science
Antibody therapy targeting CD47 and CD271 is an effective suppressor of melanoma metastasis
Alexander D. Boiko, PhD
1:35 – 1:50 p.m. / Chemical Structural Biology (CSB) Research Program Overview
Gregory A. Weiss, PhD
1:50 – 2:10 p.m. / CSB Science Presentation
Multipronged characterization of individual cancer cells with CellProfiler
Zuzanna S. Siwy, PhD
2:10 – 2:30 p.m. / CSB Science Presentation
Dynamic landscape of RNA structures in vivo reveals principles of post-transcriptional regulation
Robert Spitale, PhD
2:30 – 2:45 p.m. / Coffee Break – @ the Grand Foyer
2:45 – 3:00 p.m. / Onco Imaging & Spectroscopy (OIB) Research Program Overview
Bruce J. Tromberg, PhD
3:00 – 3:20 p.m. / OIB Science Presentation
Developing Quantitative Optical Biomarkers for Cancer Imaging
Bruce J. Tromberg, PhD
3:20 – 3:40 p.m. / OIB Science Presentation
Characterizing the Cooperation Between ErbB2 Signaling and ECM Stiffness in Driving Breast Tumor Progression: 3D vs 2.5D culture
Elliot L. Botvinick, PhD
3:40 – 3:55 p.m. / GynecologyDisease Oriented Team (formerly Women’s DOT)
Lydia Su, PhD
3:55 – 4:10 p.m. / Colon Disease Oriented Team Presentation
Digital quantification of cancer biomarkers in blood using the Integrated Comprehensive Droplet Digital Detection (IC 3D)
system
Weian Zhao, PhD
4:10 – 4:30p.m. / Seed Grant Highlight
Synthesis and anti-cancer activity of diarylmethanes
Elizabeth R. Jarvo, PhD
4:30 – 4:40 p.m. / Coffee Break – @ the Grand Foyer
Session II – The Grand Salon
4:40 – 5:00 p.m. / Strategic Initiatives
UC Irvine Health Leadership Update
Roger F. Steinert, MD, Interim DeanUC Irvine School of Medicine
Terry A. Belmont, Chief Executive OfficerUC Irvine Medical Center
5:00 – 5:30 p.m. / Strategic Initiatives
Chao Family Comprehensive Cancer Center
Richard Van Etten, MD, PhD
5:30 – 7:00 p.m. / Dinner @ the Atrium
7:00 – 8:00 p.m. / Keynote Address
Fine tuning of the hypoxia and unfolded protein response by the ubiquitin ligases Siah1/2; implications for ischemia and cancer
Ze'ev Ronai, PhD
8:00 – 10:00 p.m. / Poster Session @ the Retreat

Saturday, September 27, 2014

Session III – The Grand Salon
7:30 – 8:30 a.m. / Continental Breakfast @ the Atrium
8:30 – 8:45 a.m. / Systems, Pathways & Targets (SPT) Research Program Overview
John S. Lowengrub, PhDMarian L. Waterman, PhD
8:45 – 9:05 a.m. / SPT Science Presentation
Mapping p53 aggregation and changes in metabolism upon DNA damage using the Phasor/FLIM and number & molecular brightness analysis
Michelle A. Digman, PhD
9:05 – 9:25 a.m. / SPT Science Presentation
Targeting ERbeta in breast cancer
Ellis R. Levin, MD
9:25 – 9:40 a.m. / Cancer Prevention & Prognosis Research Program Overview
Christine E. McLaren, PhD
9:40 – 10:00 a.m. / CPP Science Presentation
Transplacentalbenzo[a]pyrene exposure and glutathione deficiency: A perfect storm for ovarian toxicity and tumorigenesis
Ulrike Luderer, MD, PhD
10:00 – 10:20 a.m. / CPP Science Presentation
Perfusion assessment in laparoscopic anterior resection (PILLAR) II trial: a phase II multi-institutional study
Michael J. Stamos, MD
10:20 – 10:30 a.m. / Coffee Break – @ the Grand Foyer
Session IV The Grand Salon
10:30 – 11:00 a.m. / Science Highlight
Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism
Selma Masri, PhD
11:00– 11:15 a.m. / GenitourinaryDisease Oriented Team (formerly Prostate DOT)
Thomas Ahlering, MD
11:15 – 11:30 a.m. / Skin Disease Oriented Team
Kenneth G. Linden, MD, PhD
11:30 – 11:50 a.m. / New Member Highlight
A short story of a long telomere: from fission yeast to melanoma
Feng Qiao, PhD
11:50 – 1:30 p.m. / Lunch – on the Sundeck
Session V – Emerging Initiatives - The Grand Salon
1:30 – 1:45 p.m. / Heme Disease Oriented Team
Angela Fleischman, MD, PhD
1:45 – 2:05 p.m. / Exaggerated response to toll-like receptor agonist contributes to excessive TNF production in myeloproliferative neoplasm
Angela Fleischman, MD, PhD
2:05 – 2:25 p.m. / Focal Adhesion Kinase Inhibitors Reverse the Stromal Adhesion Phenotype of Ikaros-Mutant B-ALL, Induce Apopotosis, and Synergize with ABL1 Tyrosine Kinase Inhibitors: A New Paradigm for Pathogenesis and Therapy of High-Risk B-ALL
Richard Van Etten, MD, PhD
2:25 – 2:45 p.m. / New insights on the elusive mechanism of action of rapamycin
David A. Fruman, PhD
2:45 – 3:05 p.m. / Starving cancer cells from inside and out
Aimee L. Edinger, VMD, PhD
3:05 – 3:35 p.m. / Science Highlight
Stem cell transplantation reverses chemobrain
Charles L. Limoli, PhD
3:35 – 3:45 p.m. / Closing Remarks
Richard Van Etten, MD, PhD
3:45 – 5:00 p.m. / Poster Session @ the Retreat
6:00 – 7:30 p.m. / Dinner –@ the Atrium