Principal Investigator/Program Director (Last, First, Middle):Raskin, Ilya

Principal Investigator/Program Director (Last, First, Middle):Raskin, Ilya

BIOGRAPHICAL SKETCH

Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
Lila, Mary Ann / POSITION TITLE
Director, Plants for Human Health Institute, and Professor, Foods Bioprocessing and Nutrition
Science Department
eRA COMMONS USER NAME
MARY_LILA
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION / DEGREE
(if applicable) / YEAR(s) / FIELD OF STUDY
University of Illinois / BSc / 1978 / Plant Sciences
University of Illinois / MSc / 1980 / Plant Pathology
University of Wisconsin / PhD / 1984 / Plant Biology

1

PHS 398/2590 (Rev. 09/04)Biographical Sketch Format Page

Principal Investigator/Program Director (Last, First, Middle):Raskin, Ilya

A. Positions and Honors.

Positions and Employment

1984 – 1995 Assistant & Associate Professor, University of Illinois, Urbana, IL

1991 – 1992 Visiting Professor, Laboratoire de Phytogenetique Cellulaire, Universite de Lausanne, Switzerland

1995-present Professor, University of Illinois, Urbana, IL

1997 – 2000 Associate Director, Functional Foods for Health Program, University of Illinois, Urbana, IL

1998 – 1999Visiting Professor, Crop & Food Research, Ltd., Palmerston North, New Zealand

2001 – 2003 Interim Head, Natural Resources & Environmental Sciences, University of Illinois, Urbana, IL

2003 – 2005Assistant Dean for Research (50% time), College of ACES, University of Illinois, Urbana, IL

2006 – 2007Interim Associate Dean for Research, College of ACES, University of Illinois, Urbana, IL

2007-2008Director, ACES Global Connect (the International arm of the College of ACES)

2008-present Director, Plants for Human Health Institute, and

Professor, Foods, Bioprocessing, and Nutrition Science Department, North Carolina State University

Other Experience and Professional Activities

1994 – 1998Elected US National Correspondent, International Association Plant Biotechnology

1997 – 1998 ESCOP Leadership Development Fellowship

1997 – 1998 CIC Academic Leadership Program Fellowship

Society for In Vitro Biology (formerly TCA), Member 1987 – present

1994 – 1995Elected Program Chair

1996 – 1998 Council Member @ Large

1998 – 2000 Strategic Planning Committee; President-Elect

2000 – 2002President

International Association of Plant Biotechnology, Member 1989 - present

1994 – 1998Elected National Correspondent

American Society for Horticulture Science, Member 1979-2003

1994 – 1999Strategic Long Range Planning Task Force

Editorial Boards & Review Panel (recent only):

1987 – 2005Associate Editor, In Vitro Cellular & Developmental Biology – Plant

2001 – 2003CIES Fulbright Australasian Review Team (chair 2003)

2003 – 2006Journal of Plant Physiology

2003 –presentJoint appointment, Division of Nutritional Sciences

2005 –presentMember and Scientific Advisory Board, Russian East European and Eurasian Center

Honors

1987 - 1988Lilly Endowment Teaching Fellowship

1995Young Faculty Research Excellence Award, College of ACES

1996 - 1998University Scholar

1997 AMOCO Award for Innovation in Undergraduate Instruction

1998 - 1999 Fulbright Senior Scholar Fellowship (to New Zealand)

2001Paul A. Funk Recognition Scholarship Award, College of ACES

2003Elected Fellow, Society for In Vitro Biology

2007Spitze Land Grant Professorial Career Award

B. Selected peer-reviewed publications (10 selected from 146 peer-reviewed publications)

(in chronological order)

1. Yousef, G., Mary Grace, Diana Cheng, Igor V. Belolipov, Ilya Raskin, and Mary Ann Lila. 2006. Comparative phytochemical characterization of three Rhodiola species. Phytochemistry 67:2380-2391.

2. Grace, Mary H., Juan A. Faraldos, Mary Ann Lila, and Robert M. Coates. 2007. ent-Beyerane diterpenoids from the heartwood of Excoecaria parvifolia. Phytochemistry 68: 546-553.

3. Campbell, Jessica, Nancy Engelman, Mary Ann Lila, and John W. Erdman, Jr. 2007. Phytoene, phytofluene, and lycopene from tomato powder differentially accumulate in tissues of male Fisher 344 rats. Nutrition Research 27:794-801.

4. Cheng, Diana, Gad. G. Yousef, Mary H. Grace, Randy B. Rogers, J. Gorelick-Feldman, I. Raskin, and Mary Ann Lila. 2008. In vitro production of metabolism-enhancing phytoecdysteroids from Ajuga turkestanica. Plant Cell Tissue and Organ Culture 93:73-83.

5. Alwerdt, Jessica, D.S. Seigler, Elvira Gonzalez de Mejia, Gad G. Yousef, and Mary Ann Lila. 2008. The influence of alternative liquid chromatography techniques on chemical complexity and bioactivity of separated proanthocyanidin mixtures. Journal of Agricultural & Food Chemistry 56:1896-1906.

6. Weaver, Connie M., Stephen Barnes, J. Michael Wyss, Helen Kim, Dorothy M. Morré, D. James Morré, James E. Simon, Mary Ann Lila, Elsa M. Janle and Mario G. Ferruzzi. 2008. Botanicals for age related diseases: from field to practice. American Journal of Clinical Nutrition 87:493S-497S.

7. Aparicio-Fernández, Xochitl, Rosalia Reynoso-Camacho, Eduardo Castaño-Tostado, Teresa García-Gasca, Elvira González de Mejía, Horacio Guzmán-Maldonado, Guillermo Elizondo, Gad Gabra Yousef. Mary Ann Lila and Guadalupe Loarca-Pina. 2008. Antiradical capacity and induction of apoptosis in HeLa cells by a Phaseolus vulgaris extract. Plant Foods for Human Nutrition 63:35-40.

8. Dey, Moul, C. Ripoll, R. Pouleva, R. Dorn, I. Aranovich, D Zaurov, A Kurmukov, M. Eliseyeva, I. Belolipov, A. Akimaliev, I. Sodombekov, D. Akimaliev, M.A. Lila, and I. Raskin. 2008. Plant extracts from Central Asia showing anti-inflammatory activities in gene expression assays. Phytotherapy Research 22: 929-934.

9. Gorelick-Feldman, Jonathan, David MacLean, Nebojsa Ilic, Alexander Poulev, Mary Ann Lila, Diana Cheng, and Ilya Raskin. 2008. Phytoecdysteroids increase protein synthesis in skeletal muscle cells. Journal of Agricultural & Food Chemistry 56:3532-3537.

10. Grace, Mary, Diana Cheng, Ilya Raskin, and Mary Ann Lila. 2008. Neo-Clerodane diterpenes from Ajuga turkestanica. Phytochemistry Letters 1:81-84.

C. Research Support

Ongoing Research Support

EPA-G2007-STAR-C3 Lila (PI)12/2007 – 11/2010

Environmental Protection Agency STAR (Science-to-Achieve-Results) program. Methods Development for Modeling Health Impacts of Global Climate Change. Environmental Protection Agency (EPA) National Center for Environmental Research (NCER).

Impacts of climate change on health benefits of a tribal Alaskan resource: Integrating traditional ecological knowledge with risk assessment through local monitoring.

Project gauges impact of global warming and environmental toxins on the sustainability and bioactive potential of wild Alaskan berries (tribal resources) and interfacing with traditional ecological knowledge of Alaska Native tribes.

Role: PI

NIH 5P50AT000477 Botanicals Center Grant Weaver (PD)3/2005-2/2010

NIH OD-00-004 Centers for Dietary Supplements Research: Botanicals. Dept. Health and Human Services. National Institutes for Health. Public Health Service.

Botanicals Center for Age-Related Diseases

Goals: Development of polyphenolic compounds (from grape/grape seed) and isoflavones from unique sources (kudzu, red cover) to enhance neurological function and bone health.

Role: subcontracted co-Investigator and Core Program member

U01 TW006674 (ICBG Program)Raskin (PD)9/2003-10/2008

National Institutes for Health (NIH/NSF/USDA Foreign Ag Services), International Cooperative Biodiversity Groups.

Building New Pharmaceutical Capabilities in Central Asia

Major goals of this project are to develop and commercialize bioactive plant, fungal, and microbial extracts from the former Soviet Union countries towards strengthening scientific ties and building economic strengths.

Role: co-Director of Plant Associate Program, and Director of Structural and Analytical Chemistry Program

Completed Research Support

NIH/NCI CA 112649-01A1Erdman (PI)3/2005-9/2008

National Institutes for Health/National Cancer Institute

Producing 14C-phytoene & phytofluene for cancer research.

Goals: Anticancer carotenoid precursors which are alleged to potentiate the bioactive effects of lycopene and other carotenoids (but are not commercially available) are synthesized and biolabeled using in vitro cell culture systems as factories for production, allowing these natural phytochemicals to be studied in terms of cancer chemoprevention potential.

Role: Co-PI

Sponsored Research Project (No Grant #)Lila (PI)3/2006-2/2007

Kraft Foods Inc.

Efficient flavonoid recovery

Goals: Produce food-grade flavonoids from continuous defined plant cell cultures and maximize yield and tailor anthocyanin and proanthocyanidin profiles

Role: PI

2005-38424-15543Paetz (PD) 7/2005-6/2007

USDA Tribal College Research Grant Program.

On the fringe of survival: How the wild environment gives native berries the edge for protection of Tribal people’s health

Goals: Project evaluated the bioactive properties towards metabolic syndrome and type II diabetes of 4 species of indigenous berries which were part of the traditional native diet, on tribal lands in North America.

Role: co-PI

Sponsored Research Agreement/ (No Grant #) Lila (PI)8/2006-10-2007

Wild Blueberry Association of North America sponsored research project,

Evaluation of natural berry fruit components that alleviate diabetes complications

Goals: Project evaluated specific anti-diabetic potential of lowbush blueberries from maritime Canada and Maine.

Role: PI

(AERI) B RFA #263-P -03-002Swanson (PI)1/2003-4/2007

USAID/Egypt. Midwest Universities Consortium for International Development (MUCIA) Cooperative Agreement for Institutional Linkages Activity US Agency for International Development [USAID]

Egypt Agricultural Exports and Rural Incomes Project

Goals: Program had 3 components: 1) Applied Biotechnology, 2) Capacity Building, and 3) Export Markets. Objectives were to improve prospects for Egyptian biotechnology and Upper Egyptian farmers through development of new production modes.

Role: Director of the Applied Biotechnology Program

PHS 398/2590 (Rev. 11/07)Page Biographical Sketch Format Page