Curriculum for the Bachelor Degree in

Medicine and Surgery

First Year Syllabus

Medical Physics

Subject: Medical Physics

Code number: 0302100

Credit hours: 2 hours

Course designation: First year/ First semester

Department: Physics (College of Science)

Course syllabus:

1-Mechanical impulse, dynamic concepts Tension-elastic concepts

2-Mechanical energy

3-Biomechanics

4-Physical agents with electric absorption and magnetic: Electrostaticenergy, basic circles, different types of flow: Pulsated , sinoidal,progressive Electric radiation and different tissues, magnetic fieldinduction and variation Biological involvement of biological structures under the magnetic field

5-Physical agent's absorption electro magnetic no ionizant: basictheory of magnetic radiation Medical instrumentation using this type of energy bands

6-Pulsated and short waves, radiotherapy, microwaves and their effects on biological system

7-Physical agent with ionizant absorption: X-ray, natural, generation, filters, absorption and effects on biological system Dosimetry, machines,Linear accelerators

8-Mechanic for fluids; physiological involvement, Bernquili low consequence and applications, impedance and frequency Caudalphysiological equation, capillary net, pressure distribution Turbulence in medicine

9-Ondulation waves, types, characteristics Mechanic waves,ultrasound Doppler effect and medical application

General and Organic Chemistry

Subject: General and Organic Chemistry

Code number: 0303108

Credit hours: 4 hours

Course designation: First year/ First semester

Department: Chemistry (College of Science)

Course syllabus:

1-Matter & life : an introduction to chemistry

2-Measurements in Chemistry

3-Atomic structure the periodic table

4-Ionic compounds

5-Molecular elements & compounds

6-Chemical reactions: classification & mass relationship

7-Gases Liquids &solids

8-Solutions

9-Reactions rates & equilibrium

10-Acid-base equilibrium

11-Nuclear chemistry

12-An introduction to organic chemistry

13-Alkanes & cycolalkanes

14-Unsaturated hydrocarbons & aromatic compound

15-Alcohols, phenols, thiols & ethers

16-Aldehydes & ketones

17-Carboxylic acids & esters

18-Amines & amides

Cell biology

Subject: Cell biology

Code number: 1501101

Credit hours: 1 hour

Course designation: First year/ first semester

Department: Anatomy

Course syllabus:

1-Introduction :

Importance of studying the cell in medicine and biology

2-Basic structure of the cell

3-The concept of prokaryote and eukaryote

4-Methods and means of study of the cell

5-Chemical foundations

6-water

7-Carbohydrates

8-Lipids

9-Nucleic acids, Proteins, The enzymes

10-Membrane structure and function

11-The nucleus structure

12-DNA ,RNA , and protein synthesis

13-Chromatin, chromosomes and genes

14-Cytoplasm

15-Bioenergetics

16-Endocytosis, degradation of cellular components, and exocytotosis

17-Reception, transudation and signaling pathways

18-Cytoskeleton

19-Cellular interactions and extra cellular matrix

20-Cell cycle, and cell death

21-Mitosis

22-Meiosis

General anatomy

Subject: General Anatomy

Code number: 1501102

Credit hours: 4 hours

Course designation: First year/ Second semester

Department: Anatomy

Course syllabus:

1-Anatomical Terminology

2-Skeleton of upper limb and joints

3-Vessels of upper limb

4-Brachial plexus and its branches

5-Bones and joints of lower limb

6-Compartments Muscle of lower limb, action and nerve supply

7-Lumbosacral plexus

8-Vessels of lower limb (ANL)

9-Thoracic cage

10-Heart and pericardium

11-Mediastinum lung & pleura

12-Anterior and posterior abdominal wall, inguinal canal

13-Peritoneum, stomach and liver

14-Small and large intestine and pancreas

15-Suprarenal, kidney, Ureter and bladder

16-Abdominal aorta, inferior vena cava, portal vein

17-Pelvic wall & floor, and vessels

18-Male and female genital system

19-Skull, cervical vertebrae& TMJ

20-Scalp and face, triangles of the neck

21-Musculoskeletal unit of the neck

22-Visceral unit of the neck

23-Neurovascular unit

24-Brain and spinal cord

25-Cranial nerves

General Histology

Subject: General Histology

Code number: 1501103

Credit hours: 3 hours

Course designation: First year/ Second semester

Department: Anatomy

Course syllabus:

Lectures

1-The Cell

2-Epithelium 1

3-Epithelium 2

4-Connective Tissue 1

5-Connective Tissue 2

6-Cartilage & Bone

7-Bone (cont.)

8-Blood 1

9-Blood 2

10-Muscular Tissue 1

11-Muscular Tissue 2

12-Nervous Tissue 1

13-Nervous Tissue 2

14-Nervous Tissue 3

15-Blood vessels

16-Lymphoid Tissue 1

17-Lymphoid Tissue 2

18-Integument

19-Respiratory system

20-Digestive system

Practical Laboratories

1-Microscopy & The cell

2-Epithelial Tissues

3-Connective Tissue

4-Cartilage & Bone

5-Blood

6-Muscular Tissues

7-Nervous Tissues 1

8-Nervous Tissues 2

9-Blood vessels

10-Lymphoid Tissues

11-Skin

12-Respiratory System

13-Digestive System 1

14-Digestive System 2

General Embryology

Course title: General Embryology

Code number: 1501104

Credit hours: 1 hour

Course designation: first year / Second semester

Department: Anatomy

Course syllabus:

1-Introduction

2-Reproductive systems male and female

3-Gametogenesis 1: cogenesis, ovulation, uterine , corpusluteum and ovarian/ cycles

4-Gametogenesis 2: spermatogenesis

5-Fertilization, clearage and blast cyst formation

6-Implantation and second week of development

7-Second week of development :bilaminar embryonic disc

8-Third week of development :gastrulation and trilaminar embryonic disc

9-Neuralation and ectoderm germ layer derivatives

10-Mesoderm germ layer and its derivative

11-Folding and gut formation

12-Embryonic period and fetal period

13-The placenta and fetal membranes

14-Prenatal diagnosis

15-Congenital malformation (birth defect) : chromosomal and genetic causes

16-Congenital malformation - environmental causes

General Physiology

Course title: General Physiology

Code number: 1502101

Credit hours: 3 hour

Course designation: first year / Second semester

Department: Pharmacology and Physiology

Course syllabus:

1 Introduction to physiology

- The internal environement and homeostasis

- Body fluid

- Diffusion

- Osmosis

- Transport of ions & molecules through the cell membrane

2 Overview of

Respiratory and renal system and their role in acid – base balance

3 Excitable Membrane Physiology

Muscle and nerves

4 Overview of

- Autonomic nervous system

- Sensory function of nervous system

- Motor function of nervous system

5 Overview of

Cardiovascular System

Lectures:

8 Lectures to cover for:

Subjects

-Introduction to physiology

-Homeostatic mechanisms

-The internal environment (extracellular fluid)

-The control systems of the body

a-negative feedback

b-positive feedback

-Transport of ions and molecules through the cell membrane

a-Diffusion (passive transport)

b-Active transport, co-transport, and counter-transport

-Body fluid

a-total

b-compartments

c-measurement of body fluid volumes

-Basic principles of osmosis and osmotic pressure

-Equilibrium when a change occurs in the volumes and osmolalities and how to calculate fluid shifts

-Edema

a-intracellular

b-extracellular

9 Lectures to cover the excitable membrane

(Muscle and Nerve):

Subjects

-Origin of bioelectric potentials (The Donnan effect and Gibbs-Donnan equation)

-Ionic bases of the resting membrane potential (RMP)

a-nerve

b-muscles

-Calculation of the RMP using Nernst equation and Goldman-Hodgkin-Katz (GHK) equation

-Ionic bases of action potential (Na, K, and Ca gates) and its properties

a-nerve action potential

b-sk muscle action potential

c-smooth muscle action potential

d-cardiac muscle action potential (five phases)

  1. non-pacemaker action potential
  2. pacemaker action potential

-Propagation of action potential (nerve and muscle)

-The refractory period (nerve, skeletal muscle, cardiac muscle, and smooth muscle)

-Rhythmicity of some excitable tissues

-Excitation of excitable tissues

-Chemical synaptic transmission and synaptic potentials

-Neuromuscular junction and neuromuscular transmission

-The end plate potential and its ionic bases

-The all or none law for excitation and contraction

-The excitation contraction coupling and molecular bases of sk muscle contraction (role of Ca++, troponin, and tropomyosin)

-Mechanics of muscle contraction (isometric, isotonic, and auxotonic contraction)

-Force-velocity relationship and length-tension relationship

-Summation of contraction (clonus and tetanization)

-Smooth muscle contraction; neural and hormonal control)

-The motor unit and recruitment technique

-Resting tension (tone) in the three types of muscles

3 Lectures for overview of the autonomic nervous system:

Subjects

-Introduction and general organization

-Chemical transmission of autonomic junctions (cholinergic and adrenergic transmission)

-Types of cholinergic and adrenergic receptors

-Effect of sympathetic and parasympathetic stimulation on specific visceral organs

-Autonomic reflexes and their role in the regulation of visceral functions

3 Lectures to cover:

-Overview sensory functions of nervous system

-Overview motor functions of nervous system

8 Lectures to cover for Cardio vascular system:

Subjects

-Overview of the CVS

-The myocardium versus the skeletal muscle

-The concept of the preload, afterload, and the myocardial contractility

-The Frank-Starling low of the heart

-The contractility and Ca++ kinetics

-The cardiac cycle and cardiac output

-The heart sound and murmurs

-The electrical activity of the heart

-The electrocardiography

-The control of heart rate and cardiac arrhythmias

-Hemodynamics

a-Blood pressure and blood flow

b-Microcirculation and lymphatics

5 Lectures to cover for respiratory system and its role in acid-base balance:

Subjects

-Overview of the respiratory system

-Mechanical aspects of breathing

-The respiratory cycle and lung volumes and capacities

-Pulmonary ventilation versus alveolar ventilation

-Pulmonary circulation

-Gas diffusion and gas transport (O2 and CO2)

-Hypoxia and asphyxia and artificial respiration

-Regulation of respiration (chemical versus non-chemical control)

-Blood pH and the buffer systems of the body

-Role of the lung in metabolic acidosis and alkalosis

General biochemistry

Course title: General biochemistry

Course code: 1503101

Credit hours: 3 credit hours (2 hrs lectures + 1 hr laboratory)

Course designation: first year / Second semester

Department: Pharmacology and Physiology

Course syllabus:

Lectures

1-Introduction into biochemistry

2-Chemical composition of biomolecules

Functional groups

Chemical reactions

3-Classes of macromolecules

4-pH and buffers

5-Amino acids

Classes

Properties

6-Polypeptides

Peptide formation

Structure (examples of fibrous and globular proteins)

Ionic properties

Folding

Physiological significance

7-Proteins

Structure

Denaturation

Classification

General functions

8-Enzymes-General description

Nomenclature

Classification

Specificity

Isozymes

9-Enzyme-Kinetics

Michaelis-Menten equation

Lineweaver-Burke plot

Competitive versus non-competitive inhibition

Other influencing factors (pH, temperature)

10-Enzyme-Regulation

11-Enzymes-Cofactors and vitamins

Types and physiological roles

12-Clinical enzymology

13-Bioenergetics

Free energy

Endergonic and exergonic reactions

High energy compounds

14-Chemistry of carbohydrates

Classification

Isomerization

15-Chemistry of lipids

16-Introduction of metabolism

Glycolysis

β-oxidation of fatty acids

Degradation of amino acids

17-Energy metabolism

Krebs cycle

Respiratory chain reaction

Oxidative phosphorylation

Practical laboratories

1-Laboratory safety and data collection

2-Liquid handling and pipetting

3-Preparation of solutions

4-Preparation of buffers and determination of pH

5-Determination of enzyme activity

6-Quantification of proteins by spectrophotometry

7-Isolation of proteins by size-exclusion chromatography

8-Detection of carbohydrate

Molecular biology

Course title: Molecular biology

Course code: 1503102

Credit hours: 2 hours

Course designation: first year / Second semester

Department: Pharmacology and Physiology

Course syllabus:

Lectures

1-Introduction

Significance of molecular biology and genetics in biology and medicine

Living systems and experimental models

History of molecular biology and genetics; genes are heritable entities

2-DNA and RNA structures

General characteristics of DNA and RNA structures

Chemical nature of DNA

DNA electrophoresis and Southern blotting

3-Structure of chromosomes

Chromosomal structure and chromatin in prokaryotes (chromosomes and plasmids) and eukaryotes

Chromosomal karyotyping

4-DNA replication

DNA replication in prokaryotes and eukaryotes

5-Concept of genes and genomes

Relationship between DNA and proteins

The role of RNA

Major types of RNA molecules

What is a gene?

Prokaryotic vs eukaryotic genes

6-RNA and gene transcription

Types of RNA in prokaryote and eukaryotes

Transcription in prokaryote and eukaryotes

Post-transcriptional regulation

7-Translation

Translation in prokaryote and eukaryotes

Post-translational regulation

8-DNA mutations and chromosomal anomalies

Types of chromosomal anomalies

Examples of genetic diseases

Types of DNA mutation

Examples of genetic mutations in human cancer

9-Mechanisms of DNA repair

10-Signal transduction

General principles

Examples of signaling pathways

11-Genomics, proteomics, and bioinformatics

Practical laboratories

1-Liquid handling and pipetting

2-Spectrophotometry and determination of DNA concentration

3-Concept of restriction endonucleases, RFLP, and DNA cloning

4-DNA fingerprinting

5-Concept of DNA electrophoresis

6-Extraction and measurement of plasmid DNA

7-Concept of polymerase chain reaction (PCR)

8-Performance of PCR

9-Performance of DNA electrophoresis

10-Bioinformatics

Biostatistics

Subject: Biostatistics

Code number: 1506102

Credit hours: 3 hours

Course designation: First year/ summer semester

Department: Public Health and Community Medicine

Course syllabus:

Lectures

1-Introduction to biostatistics

2-Sources of data

3-Types of data: Quantitative variables (continuous, discrete)

4-Types of variables: Qualitative Variables (Nominal, ordinal)

5-Research methods: Descriptive methods (cross section study, correlation study)

6-Research Methods: Analytical Methods (cohort, case control study)

7-Presentation of data: Tabular presentation (Simple frequency, Contingency, Two way classification and complex tables)

8-Presentation of data: Graphical presentation (Line graph, Bar chart, Histogram, Frequency polygon, Pie chart)

9-Presentation of data: Mathematical presentation (Measures of central tendency, and measures of dispersion)

10-Inferential statistics: Normal curve and standard scores

11-Inferential statistics: Percentiles

12-Inferential statistics: Probability distribution

13-Inferential statistics: Central limit theory

14-Inferential statistics: Abnormalities of data distribution

15-Inferential statistics: Sampling methods (simple random sample, systematic random sample, stratified sample, cluster sample, and non-probability samples)

16-Test of significance for quantitative data (eg t-test, analysis of variance)

17-Test of significance for qualitative data (Chi square)

18-Correlation and regression analysis

Seminars

1-Areas under the normal curves

2-Types of errors in statistical analysis

3-Confidence interval

4-Types of variables in experimental study

5-Problem solving: on different statistical issues

Clinical Training (computer Lab)

1-Training on the use of SPSS in statistical analysis

2-Preparation and formatting variables and its typing in an SPSS data file

3-Computation and transformation of data (eg coding)

4-Use of SUBROUTINES Frequency and CROSSTAB for presentation and tabulation of data

5-Use of SUBROUTINE GRAPH to establish BAR, LINE, HISTOGRAM, FREQUENCYPOLYGON, and PIE graphs

6-Performance of t-Test

7-Performance of Chi Square

8-Performance of ANOVA

9-Performance of correlation and Regression analysis

Computer Skill (2)

Course title: Computer Skill (2)

Course code: 0314112

Credit hours: 3 hours

Course designation: first year / summer semester

Department: Information Technology (College of Science)

Course syllabus:

1-Introduction to C++ programming

2-Memory Concepts

3-Arithmetic

4-Relational

5-Decision Making: Equality and Relational Operators

6-Control Structures

If

If/ else

While

Do while

For

Switch

Break and continue

7-Functions

8-Arrays

9-Sorting & searching Arrays

10-Passing Arrays to Functions

11-Multiple-Subscripted Arrays

1