Strategies for Examination and Management of

Acquired Brain Injury Patients

Suzanne Wickum, OD, FAAO

University of Houston College of Optometry

e-mail:

Kia B. Eldred, OD, FAAO

Diplomate in Low Vision

Michael E. DeBakey VA Medical Center

University of Houston College of Optometry

e-mail:

Course Description: A case-based approach is used to discuss the evaluation and management of patients with acquired brain injury. Demographics, types of brain injuries, visual/ocular sequelae, diagnostic testing, and management of this patient population will be reviewed. Particular attention will be given to the optometrist’s role in the rehabilitation team.

Course Objectives:

· To understand the patient populations most likely to be affected by brain injury.

· To understand the categories and severity ranking of brain injury.

· To understand the potential physical and cognitive deficits associated with brain injury.

· To understand the specific optometric examination techniques for evaluation of brain injury patients.

· To understand the specific ocular/visual complications associated with brain injury and how to appropriately manage these complications.

Outline:

Introduction - TIRR

? The Institute for Rehabilitation and Research – In-patient & Out-patient Programs

? Ranked within the top 5 rehabilitation hospitals in the US for 19 years

? Affiliation with University of Houston College of Optometry for 18 years

Project Victory

? ~30,680 US soldiers wounded in Iraq & Afghanistan

– TBI is the “signature wound”

– 20% of injuries are serious ABI or SCI

– 1800 troops suffering from penetrating TBI

– 3000 soldiers being treated for severe TBI

– 30% of troops engaged in combat > 4 months are at risk for disabling neurologic disorders from blast waves of IEDs

– 60% of injuries are due to roadside bombs & IEDs (improvised explosive devices)

– 30% of soldiers develop mental health problems (PTSD) within 3-4 months of returning to the US

Categories of Brain Injuries

? Traumatic Brain injury

? Non- traumatic brain injury

? Now defined as “Acquired” (ABI) –> Includes stroke

Traumatic Brain Injury

? Closed head injury

? Open head injury

? Penetrating head injury

Non- traumatic Brain Injury

? Anoxic Brain Injury

? Toxic-metabolic Brain Injury

Damage to General Areas of the Brain

? Occipital

? Parietal

? Frontal

? Temporal

? Brainstem

? Cerebellum

Physical Deficits with ABI

? Musculoskeletal Complications

? Heterotropic Ossification

? Spasticity

? Respiratory Complications

? GI Complications

? Swallowing Disorders

? Bowel Incontinence

? Genitourinary Problems

? Dermatological Complications

? Endocrine Complications

? Autonomic Disturbances

? Thombophlebitis

Most common causes of TBI

Epidemiology

? TBI

– 1.4 million/year in US

– 50,000 die each year

– 235,000 hospitalized

– 1.1 million treated and released from the ER

– 5.3 million (2% of US population) need long-term help with ADL

– In 2000, $60 billion dollars in direct & indirect costs

? Stroke (CVA)

– 700,000/year in US

? 500,000 first time CVA

? 200,000 prior CVA

– 160,000 die each year

– In 2005, $57 billion dollars in direct & indirect costs

– The leading cause of serious long-term disability in US

– 3rd leading cause of death in US

Pediatric Brain Injury

? 25% of brain injuries in children younger than 2 years are from physical abuse.

? Other causes of ABI – MVA, falls, leisure or sports related injuries, and violent crimes.

? Factors associated with increased risk include: male, nonwhite, low socioeconomic status, family instability, peak periods for outdoor recreation, living in a congested area.

Rehabilitation after ABI in Preschoolers

? Outcomes after ABI are difficult to predict in children at any age.

? Studies have shown – contrary to the traditional plasticity hypothesis youth is not necessarily an advantage in outcome after ABI.

? Young children are found to be very vulnerable to the effects of ABI.

? Prefrontal injury is strong indicator of negative outcome in young children.

? Consequences of ABI in young children often worsen over the years as child grows into the injury.

? Children can be overprotected, learn “helplessness,” and absence of peers.

A Team Approach

? The rehabilitation team may include:

– Physiatrists (Rehabilitation Physicians)

– Other physician specialists when needed

– Neuro-psychiatrists/psychologists

– Neuro-optometrists

– Pharmacists

– Nursing staff

– Physical & Occupational therapists

– Respiratory therapists

– Speech/language therapists

– Cognitive therapists

– Recreational/Music therapists

– Social workers

– The patient’s family members

The Role of Neuro-Optometry

? It is estimated that 90% of what we perceive is through the visual system.

? Vision problems may interfere with mobility, reading, writing, dressing, eating, locating objects, grooming, social interaction, etc.

? Vision problems may go undiagnosed if we rely on the patient to express complaints.

? Goals of the functional visual evaluation:

– Diagnose and treat patients with ocular and visual deficits.

– Counsel the patient and family as to the visual sequelae resulting from the brain injury.

– Counsel the patient, family, physicians, and therapists as to how to compensate for the patient’s visual deficits.

Common Signs & Symptoms

? Signs:

– Eye turn (strabismus)

– Closing one eye

– Head tilt or turn

– Bumping into objects

– Abnormal posture

– Balance problems

– Poor depth perception

– Nystagmus

? Symptoms:

– Double vision (diplopia)

– Blurred vision

– Inability to sustain attention on visual tasks

– Dizziness

– Headaches

– Eye strain

– Difficulty reading

Patient Case

Diplopia after TBI

Glasgow Coma Scale (GCS)

? TBI Severity Based on GCS:

– Mild TBI = GCS 13-15

– Moderate TBI = 9-12

– Severe TBI = 3-8 (patient’s score = 4)

Communication Disorders

? Aphasia: inability to express oneself &/or understand language.

? Dysarthria: difficulty in forming words because of muscle weakness. Slurred speech.

? Confabulation: “filling in” gaps in memory with fictitious events, people, or places.

? Perseveration: inappropriate persistence of a response.

Management of Acquired Diplopia

? Occlusion

? Prism

? Compensatory strategies

Vision Therapy:

? Monocular pursuits, especially into affected FOG, may help restore muscle function and prevent muscle contracture.

? In some cases where pts have fusion in at least some FOG, VT can be aimed at expanding motor fusion ranges from that area.

? Typically not started until the acute, underlying etiology has been treated/managed.

Botulinum Toxin Chemodenervation:

? Injected into the agonist muscle using an EMG needle to monitor muscle activity.

? Used in some cases of CN VI palsy.

? Initial effects within 1-7 days.

? Max effect in 1-2 weeks.

? Resolves over 4mos (+/- 2mos).

Surgery:

? Considered after 6-12 months.

? Only performed once the Dr. is convinced that the angle of deviation is stable.

? Botox can be utilized in cases of CN VI palsy prior to surgery.

Patient Case

? 14 year old male

? TBI secondary to ATV accident w/o helmet

? Cranial nerve III, IV, VI, VII palsies OD

? Cranial nerve III palsy

– Exotropia, hypotropia, ptosis, fixed-dilated pupil, loss of accommodation.

– Occlusion, prism, near add, surgery (lid, strabismus)

? Cranial nerve IV palsy

– Hypertropia, excyclotorsion

– If torsion is >10 degrees, suspect bilateral CN IV

– Occlusion, prism, compensatory strategies (head tilt, elevating near objects, tilt boards), surgery

? Cranial nerve VI palsy

– Esotropia

– Occlusion, prism, compensatory face turn, Botox, surgery

? Cranial nerve VII palsy

– Lagophthalmos

– Exposure keratoconjunctivitis

– Vigorous ocular lubrication

– Eyelid taping

– Eyelid weights

– Tarsorrhaphy

Patient Case

? 54 year old CF s/p aneurysm rupture

? Bilateral cranial nerve IV palsy

? Video footage

Accommodative Disorders

? Lag of accommodation

– Use of reading Rx or BF

– May improve over time and with decrease in meds

? Accommodative spasm / Traumatic myopia

– Difficult to manage

– May resolve with time

– May need BFs, vision therapy, cycloplegics

? Accommodative infacility

– Vision therapy

Patient Case:
Homonymous Hemianopsia

§ Fresnel Sector Prism

§ Scan Course

o Place 20 numbers/letters on the wall – 10 on each side

o Place at varying heights

o Have patient walk the course and read number/letters aloud

§ Subtest of The Brain Injury Visual Assessment Battery For Adults (biVABA)

§ Narrated Walk – I See …

o Identify Moveable Obstacles

o Identify # of People in each Aisle

o Read Aisle Signs

o Visual Scanning - Shelves

Visual Field Defect versus Visual Inattention/Neglect

? Hemi-inattention/neglect is often confused with visual field deficits - distinctly different conditions.

? When a visual field deficit is present, the patient attempts to compensate for vision loss by engaging visual attention.

? When a hemi-inattention is present, the patient has lost the attentional mechanism that drives visual search for information on the left side and does not attempt to compensate.

? Combination of hemi-inattention and VFD creates severe visual inattention, sometimes called visual neglect

Impact on Rehabilitation

? Unilateral neglect has consistently been identified as a negative predictor for a patient’s recovery of independence in daily living.

Patient Case

Hemianopsia plus neglect

Physical Deficits

? Apraxia: Inability to carry out a complex or skilled movement not due to paralysis, sensory changes, or deficiencies in understanding.

? Ataxia: A problem of muscle coordination. Caused by lesion of the cerebellum or basal ganglia.

? Adiadochokinesia: Inability to stop one movement & follow it with a movement in the opposite direction.

? Paresis: Inability to move part of the body.

Visual Field Testing

Occupational Therapy Evaluation

Clinical observations 2 weeks later:

? Would not turn head to left and look at OT

? Would hit the doorway on the left side when entering / exiting a room

? Could not follow OT to treatment room

? Did not see assessment materials on the left side

Occupational Therapy Intervention

? View Group for personal space (pen/paper tasks) and extra-personal space (mobility).

? Referral to University of Houston Center for Sight Enhancement 4 months after original stroke.

Hemi-spatial Neglect Testing

? Blind-pointing procedure

? Clock dial

? Line bisection

? Flower

? House drawing

Dynavision

? Originally designed to improve visuomotor skills of athletes

? Used to increase awareness of peripheral vision

? Use hand to strike point which is flashing

? Number of “hits” are recorded at the end of the run

? Fully programmable for quadrants, pace, etc.

? Center fixation target with number for patient to call out to monitor fixation

Neglect Intervention

? Use prompts for missing side - i.e. bold color in margin for reading, move materials in the room to the affected side.

? Use of kinesthetic feedback is helpful.

? Use of yoked prism training protocol to assist patient to compensate, possibly a more central response.

– Rossetti et. al. Nature v395:166-169,1998

Conclusion

? By being part of the rehab team, optometrists improve patients’ overall rehabilitation progress and help to improve the patients’ quality of life.