From :Dr. DineshkumarShukla,

Preliminary M.S. (Ay) Scholar,

Department of Post-Graduate studies in Shalya-Tantra,

N.K.J Ayurvedic Medical College &Research Centre,

Gumpa, Bidar-585403.

To,

The Registrar,

Rajiv Gandhi University of Health Sciences,

Bangalore, Karnataka.

Through,

The Principal,

N.K.J Ayurvedic Medical College & Research Centre,

Gumpa, Bidar-585403.

Sub: Submission of Completed Proforma for Registration of Synopsis for Dissertation.

Respected Sir,

I request you to kindly register the below mentioned subject against my name for the submission of dissertation to Rajiv Gandhi University of Health Sciences Bangalore, for the partial fulfillment of M.S. (Ay) in Shalya-Tantra.

TITLE OF DISSERTATION:

“MANAGEMENT OF SADYO VRANA WITH DURVA TAILA”

Herewith, I am enclosing completed proforma for registration of subject for dissertation.

Thanking you,

Yours sincerely,

Date :

Place : Bidar(Dr. DineshkumarShukla)

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES,

KARNATAKA, BANGALORE

PROFORMA FOR REGISTRATION OF SUBJECT FOR DISSERTATION

  1. NAME OF CANDIDATE:DR. DINESH KUMAR SHUKLA

& ADDRESSVILLEGE- TIKARI KLAN

POST OFFICE – POTARIYA

DISTRICT – JAUNPUR (U.P) 222139

  1. NAME OF INSTITUTION:N.K.J.AYURVEDIC MEDICAL

COLLEGE & P.G CENTER, BIDAR, (KARNATAKA).

  1. COURSE OF STUDY &:AYURVEDA

SUBJECT M.S(SHALYA-TANTRA).

  1. DATE OF ADMISSION:28/10/2010
  1. TITLE OF TOPIC:

“MANAGEMENT OF SADYO VRANA WITH DURVA TAILA”

6) BRIEF RESUME OF THE INTENDED WORK:

Introduction

Since time immemorial, human being has been struggling for existence and the struggle exposes him to trauma, in turn to wound which compels him to search different medicament for the care of wound. Wound and ulcer - both are synonymously used, but wound is defined as the loss of continuity of the surface epithelium due to external injury, whereas an ulcer is the break in continuity of the covering epithelium i.e. skin or mucous membrane due to molecular death [1]. It may either follow molecular death of the surface epithelium or its traumatic removal. In the same manner, VRANA is the discoloration of the damaged area due to formation of scar after healing, which remains till the body survives [2].

“uÉ×hÉÉååÌiÉrÉxqÉÉSìÖRåûÅÌmÉuÉëhÉuÉxiÉÑlÉlÉzrÉÌiÉ |

AÉSåWûkÉÉUhÉɨÉxqÉÉSèuÉëhÉCirÉÑcrÉiÉåoÉÑkÉæ: ||”Su.Su 21/40

Vrana may be classified as Nija and Agantuja[3], where Agantujavrana or Sadhyavrana with a correlation to traumatic wound are of six types and are free from tridosha involvement, which may be converted into Dushtavrana, if not treated properly. Regarding the etiology of Traumatic wound, AcharyaSushruta explains -

“lÉÉlÉÉkÉÉUqÉÑZÉæåÈzÉx§ÉæÈlÉÉlÉÉxjÉÉlÉÌlÉmÉÉÌiÉiÉå: |

lÉÉlÉÉÂmÉÉuÉëhÉÉrÉåxrÉÑxiÉåwÉÉÇuɤÉÉÍqÉsɤÉhÉqÉç ||”Su.Su 2/4

In Sadhyovrana, Pain, Oedema and Fresh bleeding are main features. So, basic principle of management includes –

  • Vedanashamaka
  • Raktasthambakaaushadiprayogas
  • Shothahara
  • Ropana karma

Durvataila seems to possess above mentioned properties and hypothetical support. Sushruta, the pioneer of surgery had advocated 60 procedures for wound care to meet the challenge of wound management.Ropanakarma, means the therapy for healing is specially emphasized inShashthi-upakrama as well as in Sapta-upakrama. Keeping in view, the above hypothesis of study is proposed to evaluate the effect of Durvataila in the management of Sadhyo-Vrana.

6.1) Need for the Study.

Vrana is the commonest painful condition that every human being suffers in their life. So, it is the responsibility of surgeon that it should be cured within short period with less pain and less cost. In the management of Sadhyovrana, AcharyaSushruta has given elaborate description in terms of Shashtiupakrama[4]. Application of Durvataila is highlighted as a treatment modality for Sadhyovrana associated with pain and bleeding [5]. Durvataila is prepared in low cost and it is easily available.

6.2) Review of Literature: -

  1. The Durvataila is selected from “CharakaSamhita” for management of Sadhyo-Vrana.

“SÕuÉÉïxuÉUxÉÍxÉ®ÇuÉÉiÉæsÉÇMüÎqmÉssÉMåülÉuÉÉ | SÉÌuÉïiuÉcɶÉMüsMåülÉmÉëkÉÉlÉÇuÉëhÉUÉåmÉhÉqÉç ||”

(cÉ.ÍcÉ. 25/93)

Oil cooked with Durva juice or Kampillaka juice or pest of Daruharidra bark is an important wound – healer.

  1. Juice of Durvaor kalka ofKampillaka or DaruharidramurchhitaTilaoil is useful in healing of the wound.

(pÉæ.U. 47/79).

Previous works done :

1)Dhore S Rajesh – TherapeuticEvaluation of Madhusarpi (on healing effect) in Sadhyo-Vrana (skin deep – chhinna-Vrana and Ghrista – Vrana – incised and lacerated wound)- 2001 (Govt. Ayurved College, Nagpur ).

2)Dixit Varsha – DoorvaGhrita in Sadyo-VranaDushta-Vrana. 1994 – (Ayurved Mahavidyalaya,Pune).

3)Narasimha – An Experimental study of the effect of Kushudra-Sevantika in Sadhyo-Vrana. 1990 (Govt. Ayurved Medical College, Bangalore).

6.3) Objective of the Study

  1. To evaluate the effect of DurvaTaila in the healing of Sadhyo-Vrana.

7) Material and Method

7.1) Source of Data:-

  1. All Cases of Sadhyo-Vranawill be registered from Shalya-Tantra OPD/IPD of Sri Siddharoodha Charitable Hospitalattached to N.K.J. Ayurvedic Medical College & PG centre,Bidar; other associated hospitals.
  2. Samhita & Modern books of Surgery.
  3. International & National Medical & Surgical Journals, Magazines, digital library and web sites
  4. Patients will be screened on clinical ground & routine laboratory investigations to establish the nature of Sadhyo-vrana.
  5. The drugs will be collected from the market with the supervision of Dravya-guna specialist and prepared in the pharmacy attached to the college under the guidance of Rasa shastra and Bhaishajyakalpana specialist

MATERIALS:

The Durvataila will be prepared by the usingTila taila-1 part, and Durva swaras-4 part. The drugs will be mixed together, heated and boiled; this is done until the appearance of TailaPakalakshana. It will be filtered and stored in an air-tight container.

7.2) Method of collecting data (including sampling procedures, if any)

Sample size minimum of 30 patients will be selected for the present study. Selection will be made by simple randomize technique. The selected patient will be categorized into two groups – in each 15 patients.

  • Group -1will be treated by DurvaTailaApplication once daily for 7 days– Trial Group
  • Group -2will be treated according to the standard method of wound management (Betadinelotion & Dressing) once daily for 7 days– Control Group.

ASSESSMENT PARAMETERS:

The assessment will be done on 3rd, 5th & 7th days. The progress will be noted in a specially prepared research case sheet as per the assessment parameters. All the collected data will be evaluated statistically as follows :

STATISTICAL DESIGN

BT1 Vs AT1 / Will be assessed / AT1 Vs AT2 / will be assessed & evaluated by “t” test
BT2 Vs AT2

SELECTION CRITERIA

Inclusion criteria:

  1. Patients will be taken with irrespective of age and sex.
  2. Patients having traumatic wound.
  3. Traumatic wound with history of < 7 days

Exclusion criteria:

  1. Infected / Pus discharging wound
  2. Wound with systemic involvement & morbid changes
  3. Suturing wounds
  4. Wound with Visceral, Bony & Spinal injuries.

ASSESSMENT CRITERIA

SUBJECTIVE CRITERIA

  1. Pain (MRC grading / VAS scale)

OBJECTIVE CRITERIA

1.Swelling

  1. Colour
  2. Discharge
  3. Granulation tissue
  4. Size of the wound (in cm)
  5. Healing index = size of wound / time of healing (in days)

7.3) INVESTIGATIONS REQUIRED

  • Total Heamogramwith TLC, DLC, Hb%, etc.

7.4) Has ethical clearance been obtained from your institution in case of 7.3?

Yes, obtained.

8) List of references-

  1. Basu S.C, Handbook of Surgery, chapter 1, current distributors, Calcutta, 1995, 2nd edition, page 1.
  2. Shastri A.D (2003), SushrutaSamhita –Poorvardha, Chaukhamba publication, Chaukhamba Sanskrit Samsthan, Varanasi, 14th Edition, Sushruta Sutra sthana 21/40.
  3. Shastri A.D (2003), SushrutaSamhita –Poorvardha, Chaukhamba publication, Chaukhamba Sanskrit Samsthan, Varanasi, 14th Edition, SushrutaChikitsasthana 1/3.
  4. Shastri A.D (2003), SushrutaSamhita –Poorvardha, Chaukhamba publication, Chaukhamba Sanskrit Samsthan, Varanasi, 14th Edition, SushrutaChikitsasthana 1/17.
  5. ShastriS.N(1992), The CharakaSamhita of Agnivesha, Chaukhamba publication, Chaukhamba Sanskrit Samsthan, Varanasi, 18th Edition, CharakaChikitsasthana 25/93

9. SIGNATURE OF THE CANDIDATE:

10. REMARKS OF THE GUIDE:

11. NAME & DESIGNATION OF:

11.1 GUIDE:DR.B.N.Murthy,M.D.

PROF. & HEAD,

P.G. DEPT. OF SHALYA TANTRA.

11.2 SIGNATURE:

11.3 CO-GUIDE:Dr.VijaykumarBiradar, M.S.

ASST. PROF

P.G.DEPT. OF SHALYA TANTRA

11.4 SIGNATURE:

11.5 HEAD OF DEPARTEMENT: Dr.B.N.Murthy, MD

PROF. & HEAD

P.G. DEPT. OF SHALYA TANTRA.

11.6 SIGNATURE:

12. 12.1 REMARKS OF THE CHAIRMAN:

& PRINCIPAL

12.2 SIGNATURE:

1