Department of Post Graduate Studies in Sharira Kriya

Department of Post Graduate Studies in Sharira Kriya

FROM,

NIMISHA. B. RAJ,

Preliminary M.D (Ayu) Scholar,

Department of Post Graduate Studies In Sharira Kriya

S.D.M.College of Ayurveda and Hospital,

HASSAN- 573201.

TO,

THE REGISTRAR,

Rajiv Gandhi University of Health Sciences Karnataka,

BANGALORE, Karnataka.

THROUGH,

The Principal and

Head of the Dept. of Kriya Shareera,

S.D.M.College of Ayurveda and Hospital, Hassan- 573201.

Subject: Submission of Completed Performa for Registration of Synopsis of

Dissertation

Respected Sir,

I request you to kindly register the below mentioned subject against my

name for the submission of the dissertation to Rajiv Gandhi University of Health

Sciences Karnataka, Bangalore, for partial fulfillment of M.D. (Ayurveda) in Sharira

Kriya.

THE TITLE OF DISSERTATION:

SUBSTANTIATION OF “RAKTEMLA SHISHIRA PRITI” WITH AMALAKI

IN RAKTA KSHAYA

Herewith I am enclosing a completed Performa of synopsis for registration of

subject for Dissertation.

Thanking you,

Yours faithfully,

Place: Hassan

Date:05/04/2012 ( NIMISHA.B.RAJ )

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES KARNATAKA

BANGALORE.

ANNEXURE - II

COMPLETED PROFORMA FOR REGISTRATION OF SUBJECT FOR DISSERTATION.

1. Name of the Candidate:NIMISHA. B. RAJ

& AddressPRELIMINARY M.D (AYU) SCHOLAR.

(IN BLOCK LETTERS)Dept. of Post Graduate Studies in Sharira KRIYA,

S.D.M. College of Ayurveda

& Hospital, P.O. Box 164,

Hassan – 573201

PERMANENT ADDRESS:NIMISHA. B. RAJ,

NEELAMBARI,

GREEN PARK,

P. O. THIRUVAMBADY,

THRISSUR, KERALA - 680022

2. Name of the INSTITUTION:S.D.M. College of Ayurveda

& Hospital, Hassan – 573201

3. Course of Study & Subject :M.D. (Ayurveda)

SHARIRa KRIYA

4. Date of Admission to:11TH AUGUST 2011

the course

5. TITLE OF THE TOPIC: SUBSTANTIATION OF “RAKTEMLA SHISHIRA PRITI” WITH AMALAKI IN RAKTA KSHAYA

6. BRIEF RESUME OF THE INTENDED WORK:

6.1 NEED FOR STUDY

Rakta is second among the Saptadhatus; chief function is Jeevana1 and is responsible for nourishing the Dhatus, bringing colour to the skin.2Rakta Kshaya is one of the common scenarios due to various etiological factors. Some features seen in Rakta Kshaya are desire for sour things, cold items etc.3

In Ayurveda, Samanya Visesha Siddhanta is one of the basic principles, where Samanya is a state of similarity which is always responsible for the augmentation of Dravya, Guna and Karma.4 ‘Amla Shishira Priti’ is a Lakshana seen in Raktakshaya5.So Amalaki which is Amla Rasa Pradhana can be considered as a suitable remedy for this. Hence this Siddhanta can be applied in Rakta Kshaya, by administering Amalaki, which is having amla rasa satisfies the Amlapriti in those who are having Rakta Kshaya.

As per our classics, Amalaki is one among the Nityaprayunjita Dravyas.6 It is capable of promoting health, preventing and curing diseases.7,8Amalaki is also well known for its Rasayana property.9 It is having Amla pradhana Pancharasa and Sita Virya.10 Amla Rasa is Raktakrit11 in nature. Raktha Kshaya is characterised by a Tejo Vruddhi12 therefore there will be a desire for the things having opposite Gunas to Teja i.e Sita. Sita Virya is also having jeevana property13 which inturn is the Pradhana Karma of Rakta. Hence Amalaki which is having Amla Rasa and Sita Virya is taken for the study to substantiate the Rakthakshaya Lakshanas.

Review of the phytochemical constituents of Amalaki mentioned by the phytochemists of 20th century, it contains all the necessary materials such as iron, vitamin C, etcwhich are required for the formation of RBC.14 Amalaki is having erythrogenic properties ie, it enhances production of red cells; facilitates the absorption of iron in the body there by increases the Hb level.15

Therefore this study is planned to revalidate the Raktemla Shishira Priti with Amalaki in Rakta Kshaya.

6.2REVIEW OF LITERATURE

All Ayurvedic compendia realize the importance of Rakta Dhatu. Acharya Susrutha proposes Rakta Dhatu is equally important as the Tridoshas.16 Acharya states that all the other Dhatus are dependent on Rakta Dhatu for their nourishment.17The properties of Rakta are Visrata, Dravata, Raga, Spandana and Laghuta.18 Acharya tells about the functions for Rakta as Varnaprasada, Mamsapushti & Jeevana.19 Susrutha also says that Rakta Dhatu is extremely important for the sustenance of life & it is therefore needed to protect this Dhatu by every possible measure.20 Acharya Caraka considered Rakta as one among the Dasapranayatanas.21 Acharya says that the living creatures are endowed with Bala, Varna, Sukha and Ayu due to Sudha Rakta.22 According to Vagbhatacharya Jeevana, Varnaprasadana & Mamsaposhana are the main functions of Raktadhatu.23

According to Vagbhata Rakta Kshaya Lakshanas are Amla Shitabhilasha, Sira Shaithilya and Twak Rukshata.24 Susrutha mentions the Shonita Kshaya Lakshana as Twak Parushata, Amla Shitabhilasha and Sira Shaithilya.25 Caraka also says Twak Parushata, Twak Sphutana and Mlanata as the Lakshanas of Rakta Kshaya.26

Amalaki is having Amlapradhana Pancharasa, Sita Virya, Madhura Vipaka and Tridoshasamaka.27 According to Dhanwantari Nighantu Vayastha, Aamalakam, Vrshyam, Jatiphalarasam, Shivam, Dhatriphalam, Shriphalam and Amritaphalam are the synonyms of the drug.28

6.3 PREVIOUS RESEARCH WORKS

1.Pandey.A.K Rakta Dhatu ek Vivechanatmaka AdhyayanaGwalior (1987).

2. Sureshkumar.Y Role of Ranjakapitta in the formation of Rakta Dhatu Nagpur (1992).

3.Selote.S Vibhinna Prakriti ke vyaktiyon mein Rakta Dhatu ka pareekshanaNagpur(1994).

4.Chaurasia. N.P Pitta Samshamana mein Amalaki ka Vivechanatmaka Adhyayana Gwalior(1985).

5.Singh Ritu Efficacy of Amalaki in Garbhini PanduBHU(2005).

6.Samble Thukkaram Raktasthapaka Aushadhiyon ka AdhyayanaJamnagar(1964) .

6.4OBJECTIVE OF STUDY

To revalidate 'Raktemla Shishira Priti' in Rakta Kshaya with Amalaki.

7MATERIALS AND METHODS

7.1 SOURCE OF DATA

30 subjects suffering from Rakta Kshaya selected from S.D.M. College of Ayurveda and Hospital, Hassan.

7.2 METHOD OF COLLECTION OF DATA

30 subjects who are full filling the criteria will be selected for the study.

INCLUSION CRITERIA

1) Subjects with Rakta Kshaya from age group 16 to 30yrs

2) Subjects of Rakta Kshaya with hemoglobin level between 8 and 11gm/dl

EXCLUSION CRITERIA

  1. Volunteers known to be suffering from any systemic illness.
  2. Patients with defective iron absorption like that of gastrectomy, gastro-

jejunostomy, and sprue syndrome.

7.3 PLAN FOR THE STUDY

30 subjects with Rakta Kshaya fulfilling the criteria selected and they will be administered Amalaki Choorna in the dose of 5g twice daily after meal with honey as Anupana.

•Duration of treatment – 1month

ASSESSSMENT CRITERIA:

Assessment will be done on the basis of improvement in the following parameters before &after completing course of administration of drug:

7.4 SUBJECTIVE PARAMETERS:

•Amlapreethi

•Shishirapreethi

•Twak Parushata

•Twak Sphutana

•Mlanata

Any person who is characterized by 4 or more or these 6 parameters are selected for the study.

7.5 OBJECTIVE PARAMETERS

LABORATORY ASSESSMENT:

Following laboratory findings has been assessed before, during and after treatment-

•RBCs count

•WBCs count

•Hb gm%

•PCV

•ESR

7.6 DOES THE STUDY REQUIRE ANY INVESTIGATIONS 0R INTERVENTION

TO BE CONDUCTED ON PATIENTS OR OTHER HUMANS OR ANIMALS

Yes

7.7 HAS THE ETHICAL CLEARANCE BEEN OBTAINED FROM YOUR

INSTITUTION?

Yes

8. LIST OF REFERENCES

  1. Paradakara HSS, Ashtangahrudaya with Sarvangasundara commentary of Arunadutta and Ayurvedarasayana commentary of Hemadri. 9th ed. Varanasi (India): Chaukambha Orientalia; 2005. p.183.
  1. Acharya JT, Susrutha Samhita with Nibandhasangraha commentary of Dalhana. Reprint ed. Varanasi (India): Chaukambha Sanskrit Sansthan; 2010. p. 377.
  1. Paradakara HSS, Ashtangahrudaya with Sarvangasundara commentary of Arunadutta and Ayurvedarasayana commentary of Hemadri. 9th ed. Varanasi (India): Chaukambha Orientalia; 2005. p. 185.
  1. Sharma RK, Caraka Samhita with Ayurvedadipika commentary of Chakrapanidutta. Reprint ed. Varanasi (India): Chaukambha Sanskrit Series Office; 2009. p. 26.
  2. Paradakara HSS, Ashtangahrudaya with Sarvangasundara commentary of Arunadutta and Ayurvedarasayana commentary of Hemadri. 9th ed. Varanasi (India): Chaukambha Orientalia; 2005. p. 185.
  1. Acharya JT, Caraka Samhita with Ayurveda Dipika commentary of Chakrapani Datta. Reprint ed. Varanasi (India): Chaukambha Orientalia; 2009. p. 38.
  1. Paradakara HSS, Ashtangahrudaya with Sarvangasundara commentary of Arunadutta and Ayurvedarasayana commentary of Hemadri. 9th ed. Varanasi (India): Chaukambha Orientalia; 2005. p. 157.
  1. Acharya JT, Caraka Samhita with Ayurveda Dipika commentary of Chakrapani Datta. Reprint ed. Varanasi (India): Chaukambha Orientalia; 2009. p. 38.
  1. Tripathy.I, Rajanighantu with Dravyagunaprakashika Hindi Commentary. 1st ed. Varanasi (India): Krishnadas Acadamey; 1982. p. 371.
  1. Sastry JLN, Illustrated Dravyaguna Vignana. 1st ed. Varanasi (India): Chaukambha Orientalia; Vol 2 2004 Vol 2 2004. p. 221.
  1. Sharma.S, Ashtanga Sangraha with Sasilekha commentary of Indu. 2nd ed. Varanasi (India): Chaukambha Sanskrit Series Office; 2008. p. 144.
  1. Acharya JT, Susrutha Samhita with Nibandhasangraha commentary of Dalhana. Reprint ed. Varanasi (India): Chaukambha Sanskrit Sansthan; 2010. p. 69.
  1. Paradakara HSS, Ashtangahrudaya with Sarvangasundara commentary of Arunadutta and Ayurvedarasayana commentary of Hemadri. 9th ed. Varanasi (India): Chaukambha Orientalia; 2005. p. 169.
  1. Sabnis.M, Chemistry and Pharmacology of Ayurvedic Medicinal Plants. 1st ed. Varanasi(India): Chaukambha Amarabharati Prakashan; 2006. p. 189,190.
  1. Acharya JT, Susrutha Samhita with Nibandhasangraha commentary of Dalhana. Reprint ed. Varanasi (India): Chaukambha Sanskrit Sansthan; 2010. p. 99.
  1. Acharya JT, Susrutha Samhita with Nibandhasangraha commentary of Dalhana. Reprint ed. Varanasi (India): Chaukambha Sanskrit Sansthan; 2010. p. 64.
  1. Acharya JT, Susrutha Samhita with Nibandhasangraha commentary of Dalhana. Reprint ed. Varanasi (India): Chaukambha Sanskrit Sansthan; 2010. p. 60.
  1. Acharya JT, Susrutha Samhita with Nibandhasangraha commentary of Dalhana. Reprint ed. Varanasi (India): Chaukambha Sanskrit Sansthan; 2010. p. 67.
  1. Acharya JT, Susrutha Samhita with Nibandhasangraha commentary of Dalhana. Reprint ed. Varanasi (India): Chaukambha Sanskrit Sansthan; 2010. p. 66.
  1. Acharya JT, Caraka Samhita with Ayurveda Dipika commentary of Chakrapani Datta. Reprint ed. Varanasi (India): Chaukambha Orientalia; 2009. p. 181.
  1. Acharya JT, Caraka Samhita with Ayurveda Dipika commentary of Chakrapani Datta. Reprint ed. Varanasi (India): Chaukambha Orientalia; 2009. p. 124.
  1. Sharma.S, Ashtanga Sangraha with Sasilekha commentary of Indu. 2nd ed. Varanasi (India): Chaukambha Sanskrit Series Office; 2008. p. 148.
  1. Sharma.S, Ashtanga Sangraha with Sasilekha commentary of Indu. 2nd ed. Varanasi (India): Chaukambha Sanskrit Series Office; 2008. p. 150.
  1. Acharya JT, Susrutha Samhita with Nibandhasangraha commentary of Dalhana. Reprint ed. Varanasi (India): Chaukambha Sanskrit Sansthan; 2010. p. 69.
  1. Acharya JT, Caraka Samhita with Ayurveda Dipika commentary of Chakrapani Datta. Reprint ed. Varanasi (India): Chaukambha Orientalia; 2009. p. 103.
  1. Pof.P.V.Sharma, Dravya Guna Vignana. 14th ed. Varanasi (India): Chaukambha Bharati Acadamey; Vol 2 1993. p. 759.
  1. Kamat SD, Studies on medicinal plants & drugs in Dhanwantari Nighantu. 1st ed. Delhi (India): Chaukambha Sanskrit Pratishthan; 2002. p. 79.

9. SIGNATURE OF CANDIDATE :

10. REMARKS OF GUIDE :

11. NAME AND DESIGNATION OF GUIDE :

(IN BLOCK LETTERS)

11.1. GUIDE : DR. GOPINATH RAJU

PROFESSOR

DEPARTMENT OF P.G. STUDIES IN

KRIYASHARIRA

S.D.M.C.A., HASSAN 573201

11.2. SIGNATURE :

11.3. HEAD OF THE DEPARTMENT : DR. GOPINATH RAJU

DEPARTMENT OF PG STUDIES IN

SHARIRA KRIYA

S.D.M.C.A., HASSAN 573201

11.4. SIGNATURE :

12.1. REMARKS OF THE CHAIRMAN

AND PRINCIPAL :

12.2. PRINCIPAL : DR.PRASANNA.N.RAO MS ( Ayu),PhD

S.D.M. College of Ayurveda and Hospital,

Hassan - 573 201

12.3. Signature with seal:

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