Dear Principal Investigator (PI):

You are receiving this message as you have submitted a protocol for using animals in research or teaching. Below is a list of items in regard to the Institutional Animal Care and Use Committee (IACUC) and your protocol.

-The entire review process can be up to 4 to 6 weeks. Reviews include a veterinary, hazardous agent, occupational health and IACUC review.

-Please reply promptly if you receive a message from the IACUC office or the IACUC coordinator on any clarifications or additions to the protocol.

-No work on this protocol can begin until you receive a written correspondence (email or letter) stating that the protocol was APPROVED from the IACUC office.

-As a PI, it is your responsibility to insure all personnel listed on your protocol have read the protocol, have completed their training and are enrolled in/waived the UT Occupational Health Program.

-Only people listed on the protocol can work on the project. A personnel amendment must be submitted to the IACUC office before any new personnel can begin work. Amendment forms are available on the IACUC website.

-If any procedures need to be changed, an amendment must also be submitted and approved prior to initiating the change.

-If any animals become sick/injured, require veterinary care, display unexpected/unrelated clinical signs, unexpected/unrelated mortality, or a high number of mortality, the IACUC office or the UT Attending Veterinarian must be contacted.

-If there is an unexpected occurrence or questions arise about any parts of the protocol, please contact the IACUC office.

-Protocols are approved for a period of 3 years; however, every year you must submit a renewal form to inform the IACUC of the number of animals used and if any personnel need to be removed from the protocol.

-Annual IACUC refresher training is typically required. As the PI, it is your responsibility to ensure all on your protocol are aware of the training and complete it once notified.

-Once your protocol is approved, you will be granted access to the IACUC SharePoint site which allows you to view your protocol, any amendments and other important information.

-Any time during the life of your protocol, you may be asked to undergo a post-approval monitoring (PAM) session to ensure the work on the animals is as written in the protocol.

Contact Information:

UT IACUC office: email: website: http://iacuc.tennessee.edu/ SharePoint site: https://utworks.tennessee.edu/iacuc/SitePages/Home.aspx

Elizabeth “Betsy” Bailey, IACUC coordinator: or 974-3631

Jessica Woofter, IACUC Administrative Support: or 974-5547

Lori S. Cole, D.V.M., Director of Animal Compliance Support: or 974-9074 (office) or 719-0214 (cell)

Patti Coan, D.V.M., PhD, DACLAM, UT Attending Veterinarian: or 974-5634 (office) or 755- 2072 (cell)