CURRICULUM VITAE – FILIP TYLŠ, MD, PHD
PROFESSIONAL EXPERIENCE:
2012 – 2015Neuroscientist and Psychiatrist at Prague Psychiatric Centre
2014 - present Psychedelic sitter with psilocybin (healthy volunteers – pilot clinical trial in CR)
and ketamin(depressive patients, off-label) (Prague Psychiatric Centre, NIMH)
2015 - presentNeuroscientist and Psychiatrist at National Institute of Mental Health (NIMH)
2015 – 2017Head of Scientific Section of Czech Psychedelic Society (CZEPS)
2017 – presentAssistant - Department of Psychiatry and Medical Psychology of Third Medical faculty, Charles University
2017 - presentPrivate psychoterapy - Tercenya atelier (
PROFESSIONAL TRAINING:
2005 - 20121st Medical Faculty of Medicine, Charles University, Prague (MD)
2012 - 2017program Neurosciences (3rd Medical Faculty, Charles University, Prague (Ph.D.)
2013Training in EEG and epileptology (Dr. Ing. S. Petránek CSc. MBA)
2012 – 2013 Experientialand growth group ingestaltpsychotherapy(atelier TERRA, Mgr. Barbara Ernest, PhDr. Radoslav Ernest)
2014ECNP Junior scientist Workshop 6-9 March 2014, Nice, France
2014 - 2020Psychoterapeutic course in Gestalt modality (Prague)
2015ECNP pilot research internship, Tartu, Estonia, 8 – 20 February 2015
2015ECNP School of Neuropsychopharmacology, Oxford, United Kingdom, 5.-10.6.2015
2016Catania International Summer School of Neuroscience, Catania, Sicily
2017Psychedelic sitter course(Mgr. Vančura, MUDr. Kudrle, Mgr. Odstrčil)
2017workshop Psilocybin in research and therapy in Oakland, California (Dr. Richards, Dr. Guss)
2018Bodywork in crisis intervention, 24-25.2.2018 (Dohnal, Dohanalová)
2018Compass pathways – therapist training for study COMP_001 (Psilocybin for treatment-resisstant depression), Lisbon, Portugal, 27.4. – 1.5. 2018
2018 – 2019Psychedelic-Assisted Therapies and Research Certificate Program (6 training meetings), CIIS, California
PROFESSIONAL ORGANIZATIONS
2011 – presentCzech Neuropsychopharmacological Association, member
2013 – presentIPEG (Interntional PharmacoEEG group), member
2015 - presentCzech Psychiatric Society ČLS JEP, member
2015 - present Czech Psychedelic Society (CZEPS), founding member
2017 - presentPsycare - psychedelic harm reduction on music festivals
AWARDS AND HONORS
ČSL JEP and ČPS travel Award for the presentation, 9-12.6.2016, Špindlerův Mlýn, Czech Republic: F. Tylš, M. Viktorinová, D. Prokopcová, J. Korčák, R. Androvičová, T. Páleníček. Akutní účinky psilocybinu a jejich vztah kmozkové aktivitě hodnocený pomocí kvantitativního EEG
ECNP Travel Award at 24th ECNP Congress 3-7.9.2011, Paris France for poster: T. Palenicek, M. Fujakova, F. Tyls, M. Brunovsky, A. Kubesova, J. Horacek, V. Krajca. Quantitative EEG in animal models of psychosis: the impact of behaviour.
WFSBP Young investigator Award for best poster at 10th World Congess of Biological Psychiatry, 29.5-2.6.2011, Prague:Tyls F., Palenicek T., Fujakova M, Brunovsky M., Horacek J., Krajca V. The role of glutamatergic ionotropic and metabotropic receptors in model of schizophrenia in rats – effect on behavior, prepulse inhibition and quantitative EEG
CINP poster prize award from XXVII CINP Congress, 6 - 10 June 2010, Hong Kong: Páleníček, T., Brunovský, M., Horáček, J., Fujáková, M., Gorman, I., Tylš, F., Krajča, V. The effect of ketamine on sensorimotor gating, EEG spectra and coherence - comparison of human and animal data.
SCIENTIFIC CONFERENCES
2018: Investigator meeting – Compass Pathways: Psilocybin for treatment resistant depression (COMP001), Lisbon, Portugal;
2017:MDMA for PTSD meeting, Leiden, Holland; International Transpersonal Conference, Prague, CR;BACI conference 2017, Bern, Switzerland; Breaking convention 2017, London, GB;PSYCHEDELIC SCIENCE 2017 Oakland, California;
2016: IPEG 2016 Nijmegen, Holland; ECNP 2016 Vienna, Austria; ICPR Amsterdam, Holland;Beyond Psychedelics, Prague, CR;
2015: OPEN psychedelic symposium, Amsterdam, Holland; ECNS 2015, Munich, Germany; NPSA 2015, Amsterdam, Holland; WFSBP 2015, Athens, Greece;
2014: ECNP 2014, Berlin, Germany;IPEG 2014, Leipzig, Germany;CINP 2014, Vancouver, Canada;Janssen-Cilag Meeting 2014, Paris, France; ECNP Workshop 2014, Nice, France;
2013: ENCP 2013, Barcelona, Spain; WFSBP 2013, Kyoto, Japan;PSYCHEDELIC SCIENCE 2013, Oakland, Califonia, USA;
2012: IPEG 2012, New York City, USA; CINP 2012, Stockholm, Sweden;
2011: EBPS 2011: Amsterdam, Holland; WSBF 2011, Prague, CR;
2010: IPEG 2010, Prague, CR.
TEACHING
2014 –2016tutor of master work on Faculty of Science (Charles University in Prague): EEG correlates of 5HT hallucinogens action in rats(Bc. Čestmír Vejmola)
2014 – 2015tutor of bachelor work on Faculty of Science (Charles University in Prague): Clinicalandexperimentaluse ofketaminein psychiatryanditsmechanisms of action (Tereza Rydzyková)
2018opponent of master work on Faculty of Food and Biochemical Technology(UCT Prague): HPLC-MS quantitative analysis of tryptamine alkaloids in Basidiomycetes fungi (Bc. Klára Gotvaldová)
LIST OF PUBLICATIONS:
Tylš F, Páleníček T, Horacek J: Neurobiology of psilocybin effects in relation to its potential therapeutic targets, in Neuropathology of Drug Addictions and Substance Misuse, edited by V.R. Preedy (Kings College London, 2016). (Chapter in book)
Kočárová R, Tylš F: Psychedelická zkušenost a její využití vpsychiatrii. In: Horáček J, Kesner L, Höschl C, Španiel F (eds): Mozek a jeho člověk, mysl a její nemoc. 1. vyd., Galén, Praha 2016. ISBN 978-80-74922-83-1 (Chapter in book, in czech)
Tylš F. (2017) The electroencephalographic changes in animal serotonergic model of psychosis – the study of EEG connectivity in relation to behavior (PhD Thesis, in czech)
Tylš, F. et al., Fenomén Psychedelie[The Psychedelia Phenomenon], Dybbuk, Prague 2017 (Book, in czech)
Tylš F, Brunovsky M, Sulcova K, Kohutova B, Ryznarova Z, Kopecek M. LATENT SCHIZENCEPHALY WITH PSYCHOTIC PHENOTYPE OR SCHIZOPHRENIA WITH SCHIZENCEPHALY? A CASE REPORT AND REVIEW OF LITERATURE. Clinical EEG & Neuroscience (in press) IF 2.163
Bravermanová, A., Viktorinová, M., Tylš, F., Novák, T., Androvičová, R., Korčák, J., ... & Vlček, P. (2018). Psilocybin disrupts sensory and higher order cognitive processing but not pre-attentive cognitive processing—study on P300 and mismatch negativity in healthy volunteers.Psychopharmacology, 1-13. IF 3.31
Hložek, T., Uttl, L., Kadeřábek, L., Balíková, M., Lhotková, E., Horsley, R. R., ... Tylš, F., & Kuchař, M. (2017). Pharmacokinetic and behavioural profile of THC, CBD, and THC+ CBD combination after pulmonary, oral, and subcutaneous administration in rats and confirmation of conversion in vivo of CBD to THC.European Neuropsychopharmacology,27(12), 1223-1237. IF 4.24
Androvicova, R., Horacek, J., Tintera, J., Hlinka, J., Rydlo, J., Jezova, D., ... Tylš, F & Roman, M. (2017). Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study. Psychopharmacology, 1-11. IF 3.54
Páleníček, T., Lhotková, E., Žídková, M., Balíková, M., Kuchař, M., Himl, M., ... Tylš F, & Horsley, R. R. (2016). Emerging toxicity of 5, 6-methylenedioxy-2-aminoindane (MDAI): Pharmacokinetics, behaviour, thermoregulation and LD50 in rats.Progress in Neuro-Psychopharmacology and Biological Psychiatry,69, 49-59. IF 1.078
Tylš, F., Pálenícek, T., Kaderábek, L., Lipski, M., Kubešová, A., & Horácek, J. (2016). Sex differences and serotonergic mechanisms in the behavioural effects of psilocin.Behavioural pharmacology,27(4), 309-320. IF 2.148
Kubesova, A., Tejkalova, H., Syslova, K., Kacer, P., Vondrousova, J., Tyls, F., Fujakova, M., Palenicek., Horacek, J. (2014). Biochemical, histopathological and morphological profiling of a rat model of early immune stimulation: relation to psychopathology. PloS one, 10(1), e0115439-e0115439.IF 3.230
Fujáková, M., Páleníček, T., Brunovský, M., Gorman, I., Tylš, F., Kubešová, A., Řípová, D., Krajča, V., Horáček, J. The effect of ((−)-2-oxa-4-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY379268), an mGlu2/3 receptor agonist, on EEG power spectra and coherence in ketamine model of psychosis.Pharmacology Biochemistry and Behavior, 2014, roč. 122, č. July, s. 212-221. ISSN: 0091-3057.IF 2,608
Tylš, F., Páleníček, T., Horáček, J. Psilocybin - summary of knowledge and new perspectives.European Neuropsychopharmacology, 2014, roč. 24, č. 3, s. 342-356. ISSN: 0924-977X. IF 4,595.
Palenicek T, Fujakova M, Brunovsky M, Horacek J, Gorman I, Balikova M, Rambousek L, Syslova K, Kacer P, Zach P, Bubenikova-Valesova V, Tyls F, Kubesova A, Puskarcikova J, Hoschl C (2012) Behavioral, neurochemical and pharmaco-EEG profiles of the psychedelic drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in rats. Psychopharmacology (Berl) IF 4.077
Páleníček T, Fujáková M, Brunovský M, Balíková M, Horáček J, Gorman I, Tylš F, Tišlerová B, Šoš P, Bubeníková-Valešová V, Höschl C, Krajča V. EEG spectral and coherence analysis of ketamine in rats – correlation with behavioral effects and pharmacokinetics. Neuropsychobiology 2011;63(4):202-218. IF 2.147
Ševčík, L., Tylš, F. Psychedelika jako amplifikátor placebo efektu. Psychiatrie. 2017, 21(4), 175-180.(in czech, no IF)
Viktorinová, M., Tylš, F. Nevědomé procesy lidské mysli: poznatky z psychedelického výzkumu. Psychiatrie. 2016, 20(2), 100-107.(in czech, no IF)
Tylš, F. Neurobilogie psilocybinu ve vztahu k jeho potenciálnímu terapeutickému využití. Psychiatrie. 2015, 19(2), 104-112. (in czech, no IF)
Nováková P., Tylš F., Kubešová A., Kadeřábek L., Fujáková M., Páleníček T. Role kanabinoidního systému v indukci, neurobiologii a terapii psychotických onemocnění. Psychiatrie, 2014; 18 (4): 186-192.(in czech, no IF)
H-index: 5, Times Cited: 102 (29.5.2018)
ORCID 0000-0002-8337-6999
ResearchID C-4542-2018
1