Controlled Release Dosage Forms: from Ground to Space. P.COLOMBO,R.BETTINI, M.T.PERACCHIA

Papers from 2000

Influence of flow and packing properties on the pneumatic conveying of powdered mixtures for direct compression. C. D’ANDRIA, G. MASSIMO, P.L. CATELLANI, P. SANTI, R. BETTINI, L. BIANCO, P. COLOMBO, Pharmaceutical Technology Europe, January 2000, 17-23

Controlled release dosage forms: from ground to space. P.COLOMBO,R.BETTINI, M.T.PERACCHIA, P.SANTi. Eur.J.Drug Metab.Pharmacokinet. 1996,No.2, pp.87-91

Ionized prodrugs of Dehydroepiandrosterone for transdermal iontophoretic delivery. S. LANERI, A.SACCHI, E. ABBIGNENTE DI FRASSELLO, E. LURASCHI, P. COLOMBO, P.SANTI. Pharmaceutical Research. Vol. 16, No 12, 1999 1818-1824

Response surface methodology applied to fluid bed granulation. P. WEHRLÉ, P. COLOMBO, P. SANTI, R.BETTINI, A. NORA, C. TENORE, P.L. CATELLANI. Pharmaceutical Technology Europe April 2000, 36-46

Disintegration Propensity of Tablets Evaluated by Means of Disintegrating Force Kinetics, G.MASSIMO, P.L.CATELLANI, P.SANTI, R.BETTINI, G.VAONA, A.BONFANTI, L.MAGGI, P.COLOMBO. Pharmaceutical Development and Technology, 5(2), 163-169 (2000).

Swellable matrices for controlled drug delivery: gel-layer behaviour, mechanisms and optimal performance. P. COLOMBO, R.BETTINI,P.SANTI,N.A.PEPPAS. PSTT Vol.3, No 6 June 2000,198-204.

Swelling force development as a result of hydrate formation in diclofenac sodium or nitrofurantoin tablets. R.BETTINI, F.GIORDANO, C.DONINI, G.MASSIMO, P.L.CATELLANI, P.COLOMBO. S.T.P. PHARMA SCIENCES 10 (4) 335-339, 2000. 09-11

Drug release from swelling-controlled system. P.COLOMBO, P.SANTI, R.BETTINI, C.S.BRAZEL, N.A.PEPPAS. Handbook of Pharmaceutical Controlled Release Technology, Ed D.L.Wise, Marcel Dekker, Inc. New York; Basel. Chapter 9. 2000

Effect of drying methods on retention of moist sucralfate gel properties. L.MAGGI, P.L.CATELLANI, E.FISICARO, F.ZANI, G.MASSIMO, P.COLOMBO. AAPS PharmSciTech,2000; 1 (3) article 28 (http://www.pharmscitech.com/)

Design of triptorelin nanospheres for transdermal iontophoretic administration. S.NICOLI, P.SANTI, P. COUVREUR, G. COUARRAZE, P. COLOMBO, E. FATTAL. International Journal of Pharmaceutics, 214,31-35,2001

State of the art and new perspectives on dry powder inhalation. C.TERZANO, P.COLOMBO, European Review for Medical and Pharmacological Sciences, 1999;3: 247-254.

Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate. R.BETTINI, P.L.CATELLANI, P.SANTI, G.MASSIMO, N.A.PEPPAS, P.COLOMBO. Journal of Controlled Release 70 (2001) 383-391

Biopharmaceutical aspects of nasal and pulmonary drug delivery. P. COLOMBO, D.COCCONI, P.SANTI, R.BETTINI, G.MASSIMO, P.L.CATELLANI, C.TERZANO, in Pharmacokinetics Optimization in Drug Research. Biological,Physicochemical, and computational Strategies. Eds. B.Testa, H.van de Waterbeemd, G. Folkers, R.Guy. VHCA, Verlag Helvetica Chimica Acta, Zurich, Switzerland. Wiley-VCH, Weinheim, Germany, pp. 173-188, 2001

Controlled Delivery of biotechnological products. S. CONTI, L. POLONELLI, R. FRAZZI, M. ARTUSI, R. BETTINI, D. COCCONI, P. COLOMBO, Current Pharmaceutical Biotechnology, 2000, I , 313-323

Plasma and skin concentration of 5-methoxypsoralen in psoriatic patients after oral administration, A.ZUCCHI, E.RAHO, B.MARCONI, S.NICOLI, M.SANTINI, F.ALLEGRA, P.COLOMBO, R.BETTINI, P.SANTI, The Journal of Investigative Dermatology, VOL. 117, NO.2, AUGUST 2001, 379-382.

Liberation controlée des medicaments: voies et formes utilisées, S.NICOLI, P.COLOMBO, Annales Pharmaceutiques Francaises, 59: 227-231, 2001

Hydrophilic polymers for matrix systems. P.COLOMBO, R.BETTINI, P.SANTI, New Trends in Polymers for oral and parenteral administration : from design to receptors. Paris, 12-13 march 2001. Editions Santé, Minutes pg 99-106.

Physical and chemical enhancement of transdermal delivery of triptorelin. S.NICOLI, S. RIMONDI, P.COLOMBO, P.SANTI, Pharmaceutical Research, Vol 18, No 11, November 2001, 1634-1637.

Influence of Layer Position on in Vitro and in Vivo Release of Levodopa Methyl Ester and Carbidopa from Three-Layer Matrix Tablets", R. BETTINI, D. ACERBI, G. CAPONETTI, R. MUSA, N. MAGI, P. COLOMBO, D. COCCONI, P. SANTI, P.L. CATELLANI, P. VENTURA. European Journal of Pharmaceutics and Biopharmaceutics, 53, 2002, pp. 227-232.

Caffeine microparticles for nasal administration obtained by spray drying, C. SACCHETTI, M. ARTUSI, P. SANTI AND P. COLOMBO, International Journal of Pharmaceutics, 242 (2002) 335-339

Preparation of poly(methacrylic acid-g-poly(ethylene glycol) nanospheres from methacrylic monomers for pharmaceutical applications, C.DONINI, D.N.ROBINSON, P.COLOMBO, F.GIORDANO, N.A.PEPPAS; International Journal of Pharmaceutics 245 (2002) 83-91

Characterization of a surface modified dry powder inhalation carrier prepared by “particle smoothing”, P.M. YOUNG, D.COCCONI, P. COLOMBO, R. BETTINI. R. PRICE, D.F.STEELE, M.J.TOBY, Journal of Pharmacy and Pharmacology, 2002,54: 1339-1344

Distribution and quantification of polyethylenimine oligodeoxynucleotide complexes in human skin after iontophoretic delivery using confocal scanning laser microscopy. C.BRUS, P.SANTI, P. COLOMBO, T. KISSEL, Journal of Controlled Release 84 (2002) 171-181

Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies. M.ARTUSI, P.SANTI, P.COLOMBO, H.E.JUNGINGER, International Journal of Pharmaceutics 250 (2003) 203-213

Skin permeation of 5-mehtoxypsoralen from topical dosage forms, G.COLOMBO, M.ARTUSI, P.SANTI, P.COLOMBO, R.BETTINI, A.ZUCCHI, S.NICOLI, Drug Dev.Ind.Pharm. Vol 29,No 2,pp. 247-251,2003

In vitro and in vivo study of 5-mehtoxypsoralen skin concentration after topical application, G. COLOMBO, A. ZUCCHI, F. ALLEGRA, P.COLOMBO, F.ZANI, P.SANTi, Skin Pharmacol. Appl.Skin Physio. 2003;16; 103-136

Disintegration force kinetics as formulation tool for pharmaceutical development of spironolactone conventional release tablets G.MASSIMO, R. BETTINI, P: SANTI, S. NICOLI, F. ZANI, P. Colombo, AAPS Pharm Sci Tech 2003;4 (2) Article 17 (http://www.pharmscitech.org)

Characterization of the permselective properties of rabbit skin during transdermal iontophoresis, S. NICOLI, M. CAPPELLAZZI, P. COLOMBO, P. SANTI, Journal of Pharmaceutical Sciences, vOL.92, NO.7, July 2003, 1482-1488

Innovations en matiere d’administration des medicaments: voie orale, transdermique et par inhalation. P. COLOMBO, R. BETTINI, G. MASSIMO, P. SANTI, B.T: Gattefossé N° 96- Tome 2- 2003, pg 57-62.

Validation of a Clean-in-Place System on a Capsule Filling Machine. S. NICOLI, R. BONORA, R. TREBBI, G. MASSIMO, P. L. CATELLANI, P. COLOMBO, R. BETTINI, Pharmaceutical Technology Europe October 2003 27-35

Post-iontophoresis transport of ibuprofen lysine across rabbit ear skin. P. SANTI, S. NICOLI, G. COLOMBO, R. BETTINI, M. ARTUSI, S. RIMONDI, C. PADULA, P. RIZZO, P. COLOMBO. International Journal of Pharmaceutics Volume 266, Issues 1-2, 6 November 2003, Pages 69-75

Preparation and characterization of chitosan based micro networks : transposition to a prilling process. L.MARTINEZ, F.AGNELY, R.BETTINI, M.BESNARD, P.COLOMBO AND G.COUARRAZE . Journal of Applied Polymer Science, volume 93, issue 6 (15 September), p.2550-2558, 2004.

Effect of Chemical Enhancers and Iontophoresis on Thiocolchicoside Permeation accross rabbit and Human Skin in vitro. M.ARTUSI, S.NICOLI, P.COLOMBO, R.BETTINI, A. SACCHI, P.SANTI. Journal of Pharmaceutical Sciences submitted

Bioadhesive transdermal film containing caffeine. S. NICOLI, V. AMORETTI, P. COLOMBO, P. SANTI, Skin Pharmacology and Physiology 2004;17: 119-123

FERRARI F., COCCONI D., BETTINI R., GIORDANO F., SANTI P., TOBYN M., PRICE R., YOUNG P., CARAMELLA C., COLOMBO P. (2004). The Surface Roughness of Lactose Particles Can Be Modulated by Wet- Smoothing Using a High-Shear Mixer. AAPS PHARMSCITECH (on line). vol. 5, pp. 1-6 ISSN: 1530-9932. Article 60 (http://aapspharmscitech.org).

D.COCCONI, C.PENOTTI, R.BETTINI, P.YOUNG, R.PRICE, P.COLOMBO, C.MARRIOT: Inhalation mixtures of antiasmathic drugs with smoothed lactose, Respiratory Drug Delivery VIII,2002, 739.

Surface smoothing of lactose particles for dry powders inhalers. COLOMBO P., CATELLANI P.L., MASSIMO G., SANTI P., BETTINI R., COCCONI D., CAGNANI S., VENTURA P., Respiratory Drug Delivery VII, Palm Harbor, May 14-18 2000, 629-632.

A novel spray dried formulation for pulmonary administration of insulin CAGNANI.S., COLOMBO P., R.BETTINI, VENTURA P. Respiratory Drug Delivery IX, April 25-29,2004, 813-816

Chimeral agglomerates of microparticles for nasal administration of analgesic powders. RUSSO P., COLOMBO P., BETTINI R., SONVICO F., BUTTINI F. Respiratory Drug Delivery IX, 2004, 817-820

Preparation and characterization of chitosan based micro networks: Transposition to a prilling process. L. MARTINEZ, F. AGNELY, R. BETTINI, M. BESNARD, J. L. PASTOL, P. COLOMBO, G. COUARRAZE. Journal of applied polymer science, Vol 93, 2550-2558, 2004

Drug-b-Cyclodextrin Containing Pellets Prepared with a High-Shear Mixer A. GAINOTTI, R. BETTINI, A. GAZZANIGA, P. COLOMBO, F. GIORDANO. Drug Development and Industrial Pharmacy. Vol. 30, No. 10, pp. 1061–1068, 2004

Chimeral agglomerates of microparticles for the administration of caffeine nasal powders. P.RUSSO, F.BUTTINI, F.SONVICO, R. BETTINI, G. MASSIMO, C. SACCHETTI, P. COLOMBO, P. SANTI. Journal of Drug Delivery Science and Technology 14, N° 6, 449-454, 2004

Effect of Chemical Enhancers and Iontophoresis on Thiocolchicoside Permeation across Rabbit and Human Skin In Vitro M. ARTUSI, S. NICOLI, P. COLOMBO, R. BETTINI, A. SACCHI, P. SANTI. Journal of Pharmaceutical Sciences, vol. 93, no. 10, 2431-2438

Mechanisms of formation and disintegration of alginate beads obtained by prilling, P. DEL GAUDIO, P. COLOMBO, G. COLOMBO, P. RUSSO, F. SONVICO International Journal of Pharmaceutics302 (2005) 1-9.

Bpps Folate-Conjugated Iron Oxide Nanoparticles for Solid Tumor Targeting as Potential Specific Magnetic Hyperthermia Mediators: Synthesis, Physicochemical Characterization and in Vitro Experiments" F. SONVICO, S. MORNET, S. VASSEUR, C. DUBERNET, D. JAILLARD, J. DEGROUARD, J. HOEBEKE, ETIENNE DUGUET, P. COLOMBO AND P. COUVREUR Bioconjugate Chemistry, in press

Establishment of an in vitro model expressing the folate receptor for the investigation of targeted delivery systems F. SONVICO, C. DUBERNET, V. MARSAUD, M. APPEL, H. CHACUN, B. STELLA, M. RENOIR, P. COLOMBO, P. COUVREUR. J. Drug Del. Sci. Tech., 15 (1) 000-000 2005

Metallic colloid nanotechnology, applications in diagnosis and therapeutics. F. SONVICO, C. DUBERNET, P. COLOMBO, P. COUVREUR. Curr Pharm Des. 2005;11(16):2095-105.

Effect of residual water content on the physico-chemical properties of sucralfate dried gel obtained by microwave drying. A.GAINOTTI, E.LOSI, R.BETTINI, P.COLOMBO, F.SONVICO, D.BARONI.P.SANTI, G.COLOMBO, Drug Development and Industrial Pharmacy, 31:645-652,2005