RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCEBANGALORE, KARNATAKA
COMPLETED PROFORMA FOR REGISTRATIONOF SUBJECT FOR DISSERTATION
“Efficacy of Nimbadi Churna in the management of Akala Palitya”
BY
DR RAJANI R. SUNKADBAMS
DEPT OF SHALAKYA TANTRA
S.D.M COLLEGE OF AYURVEDA
HASSAN -573201
GUIDE:
DR ABHIJITH H.N. M S (AYU)
ASSistant professor
dept of P.G STUDIES IN SHALAKYA TANTRA,
S.D.M COLLEGE OF AYURVEDA
HASSAN 573201
2012 – 2013
S.D.M. COLLEGE OF AYURVEDA
HASSAN
From,
Dr. Rajani R Sunkad.
Preliminary M.S. (Ayu) Scholar
Dept. of Post Graduate Studies in Shalakya Tantra,
S.D.M. College of Ayurveda and Hospital,
Hassan – 573 201.
To,
The Registrar,
Rajiv Gandhi University of Health Sciences Karnataka,
Bangalore.
Through,
The Principal and
Head of the Dept. in Shalakya Tantra,
S.D.M. College of Ayurveda and Hospital,
Hassan- 573 201
Respected Sir,
Subject: “Submission of synopsis of M.S. (Ayu:) with compliance for
Registration of subject for dissertation”.
I request you to kindly register the below mentioned subject against my name for the submission of the dissertation to Rajiv Gandhi University of Health Sciences Karnataka, Bangalore for partial fulfillment of M.S. (Ayurveda)
Title of the Dissertation:
“Efficacy of Nimbadi Churna in the management of Akala Palitya”
Herewith I am enclosing completed Performa of synopsis for registration of subject for Dissertation.
Thanking you,
Yours faithfully,
Date:
Place: Hassan (Dr. Rajani R. Sunkad)
Rajiv Gandhi University of Health Sciences Karnataka
Bangalore.
ANNEXURE - II
Completed Performa for Registration of Subject for Dissertation.
1. Name of the Candidate :DR. RAJANI R. SUNKAD
AND Address RELIMINARY M.S. (AYU) SCHOLAR.
(IN BLOCK LETTERS) Dept. of Post Graduate studies in Shalakya TANTRA, S.D.M. College of Ayurveda
AND Hospital, P.O. Box 164,
Hassan – 573 201.
Permanent address :DR. RAJANI R. SUNKAD
D/o R T Sunkad,
Mrutyunjay nagar,
near dixit gas godown,
ranebennur-581115.
Dist:- haveri.
2. Name of the Institution: S.D.M. College of Ayurveda
AND Hospital, Hassan – 573 201.
3. Course of the Study AND:M.S. (Ayurveda) –
SUBJECT SHALAKYA TANTRA
4 DATE OF ADMISSION TO:22nd DEC 2012.
the course
5. TITLE OF THE TOPIC :“ EFFICACY OF NIMBADI
CHURNA IN THE MANAGEMENT OF AKALA PALITYA”.
6. BRIEF RESUME OF THE INTENDED WORK:
6.1 need for the study
Akala Palitya has been mentioned in the Ayurvedic classics among Shirokapalgata Vyadhis1-3. Excess Lavana rasa Sevana during pregnancy is causative factor for Akala Palitya as mentioned in classics4. Akala Palitya According to classics defined as Keshashuklayatam5, Kalapurvapakva6, Asamaya utpanna7.The Trichological Society defined Canities as a pigment deficiency frequently seen in middle aged people of either gender8.It is frequently noted as commencing at the anterior parietals and Processing over the vertices9.
The stress and strain of modern life induces premature aging. Akala Palitya is an accompaniment of premature graying and possesses a clinical challenge to the medical practitioners. Although hair graying, or canities, is a common process occurring in people as they age, an unknown percentage of individuals experience premature graying from familial inheritance or pathologic conditions10.The incidence of Akala palitya is on increase, particularly in tropical and developing countries11.
There are a large number of home remedies as well as over the counter products available in market such as dyes, lotions, etc. that are used in the management of Akala palitya. However these products often carry adverse reactions such as increased hairfall,increased graying of otherwise normal hair and sometimes allergic reactions. They pose alarming threat on general health.
Akala Palitya is a burning problem as large percent of population especially young men and women in present times are suffering. In classics they explained Nimbadi churna is effective in treating Akala Palitya as the medicine is Tridoshahara and Keshya12.
The present clinical study is intended to fill the gap where an effective, safe and non sensitizing way of treating Akalaja Palitya is to be made available. In view of these inputs a clinical trial to assess the efficacy is designed with the title, “Efficacy of Nimbadi churna in the management of Akala Palitya”.
6.2) Review of literature:
Palitya disease has been explained in all Samhitas in different context. So in Samhita Kala Akala Palitya is mentioned under Shirogata Vyadi13, where as other authors explained it in Shiro Kapalgata Rogas1-3 and Kshudra Rogadhikar.14-18
Depigmentation of the hair occurring due to strain, exertion, excessive hunger, weeping, the over heat is produced in the body that propagates towards the head along with vitiated Pitta dosha affects the hair roots and it causes disease Palita. In Vata predominance hair becomes rough, dry, brownish. In pitta predominance hair becomes yellowish with burning sensation. In Kapha predominance hair becomes whitish oily thicker, lengthy. In Tridoshaja all the above symptoms are found.19
According to modern it is defined as the onset of graying before the age of 20 in Caucasians and before the age of 30 in Africans and Asians or alternatively when 50% or more of scalp hair turns gray before the age of 5010.In classics, Yuva age mentioned up to 34yrs.20
Recently modern science has developed a branch deal with pathophysiology, care, preservation of hair known as Trichology. Earlier hair and its disorders were described under heading skin diseases. Gray hair is an optical illusion caused by the presence of white hair amongst other black hair, and this look is also referred to colloquially as “Salt and Pepper”.10
In Basavarajeeyam , Palitya is listed as Urdvwajatrugata vyadhi and its treatment explained in Kshudra roga. Nimbadi churna internal medication has been explained for Palitya.12
Nimbadi Churna is having following Drugs:- Krishna Nimba(Kaiderya-Murraya koengii(L). Sprengel), Shunti(Zingiber officinale), Maricha(Piper nigrum), Pippali(Piper longum Linn),Vibitaki(Terminalia bellirica), Amalaki(Emblica officinalis),Haritaki( Terminalia chebula),Bakuchi(Psoralia corylifolia), Krishna jeeraka(Carum bulbocastanum), Kantaloha, Krishna tila(Sesamum orientale), which are having Tridoshahara property.
a) Previous researches on this topic
1. Sunita Rani : Clinical evaluation of Nasya in Palitya, R.G.U.H.S,
GAMC ,Mysore-1993.
2. Sunil Kumar S.: Management of Akala Palitya with Bringaraja Taila Nasya and internal use of Kaseesa Bhasma, A.P.University, Vijayawada. Dept.of Shalakya Tantra. 1993.
3. Nalini C.: A clinical study on Akala Palitya and its management,
R.G.U.H.S, Bangalore,Dept.of Shalakya Tantra 1997.
4. Kaleshwar Rao : Role of Nimbadi Taila Nasya with or without Neelibringadi taila Lepana in the management of Plitya, Hydrabad-1999.
5. Chawda Harsha: Role of Nirgundi Patra Palitagna Lepa and Neeli Taila in management of Palitya, G.A.U., Dept. of Kayachikitsa. 2000.
6. Kaushal Randhir: A comparative and clinical study in between Shirovirechana- Poorvaka Mahaneela Taila Shirobasti and Brungaraja Rasayana in Palitya Roga, Rajastan university, Jaipur, Dept.of Kayachikitsa.2000.
7. .Kamala Kumari L.: Clinical management of akala palitya (grey hair) with triphaladi lepa with and without nimba beeja taila, A.P.University, Vijayawada. Dept. of Shalakya Tantra. 2005.
8. Sabareesh M: Evaluation of combined effect of Nimba taila Nasya and Bringaja taila Shiroabyanga in Akala Palitya an Observational clinical study,RGUHS,DGM Ayurveda medical college,Dept of Panchakarma, 2007.
Results: - In the study, no patients had very good as well as good response. Among 30 patients, 13patients (43.33%) had satisfactory response to the treatment (25%- 50%) improvement in all the parameter).17 patients (56.66%) had poor response to the treatment (25%) improvement in all the parameters.)
9. Lokanath J: Evaluation of Bringaraja taila Nasya with and without Bhringarajadi Rasayana in the management of Akala Palita-A comparative study,RGUHS,Bangalore,Dept. of Shalakya Tantra.2011.
6.3Objectives of the study:
To evaluate the efficacy of Nimbadi Churna in the management of Akala
Palitya.
7.Materials and methods:
7.1Source of data:
Patients with the classical signs and symptoms of Akalaja Plitya will be selected from outpatient department and inpatient department of Shalakya Tantra, SDM college of Ayurveda and Hospital, Hassan for the clinical study.
7.2Methods of collection of Data:
a. Study Design- An observational clinical study.
b. Sample size: - Single group.
30 patients who are fulfilling the criteria will be selected for the present clinical study.
c. Treatment Plan:-Preparation of medicine
Nimbadi churna will be prepared as told in the classics Basavarajeeyam, in Kshudra Roga, Mixing fine powder of Krishnanimba(kaiderya)12 – 1 Part, and remaining ten drugs, Trikatu-Shunti, Maricha, Pippali, Triphala-Vibitaki, Amalaki, Haritaki, Krishnatila, Kantaloha, Bakuchi, Krishnajeeraka should be equal to the quantity of Krisnanimba.
Sl No / Sanskrit Name / Botanical Name/ English Name / Part Used / Proportion1 / Krishnanimba(Kaiderya) / Murraya Koengii(L) / Whole plant / 500gm
2 / Shunti / Zingiber officinale / Rhizome / 50gm
3 / Maricha / Piper nigrum / Fruit / 50gm
4 / Pippali / Piper longum Linn / Fruit / 50gm
5 / Haritaki / Terminalia chebula / Fruit rind / 50gm
6 / Vibitaki / Terminalia bellirica / Fruit rind / 50gm
7 / Amalaki / Emblica officinalis / Fruit rind, Seeds / 50gm
8 / Krishna tila / Sesamum orientale / Seeds / 50gm
9 / Kantaloha / Magnetic iron Calx / Bhasma / 50gm
10 / Bakuchi / Psoralia corylifolia / Seeds / 50gm
11 / Krishnajeeraka / Carum bulbocastanum / Fruits / 50gm
Note: - The proportion is taken for 1kg preparation of Nimbadi Churna
Source of drug and authenticity: -
Kumara Ayurveda Ashrama, Bengalooru which is GMP certified.
Posology and mode of administration:-
Nimbadi churna administered orally on empty stomach in two divided doses morning and evening with water in Bidalakapada Matra.21 (1 Karsha= 11.5 gm).22
Study duration:-
30 patients of Akalaja Palitya will be administered Nimbadi Churna for 60 days.
Follow-up:-
During the course of treatment observation is done for a week and later once in15 days till the completion of study. Follow up will be done for a period of 2 months at an interval of 1 month.
d.Inclusion Criteria:-
1. Patients age less than 35yrs.
e. Exclusion Criteria:-
1. Systemic disorders like Albinism, Hyperthyroidism, hypothyroidism, Vitiligo.
2. Nutritional deficiency, Pernicious Anemia.
f. Diagnostic Criteria:-
Is made on the basis of clinical signs and symptoms of Akala Palitya as mentioned in Ayurvedic classics, like
1. Split/broken hair (Sputitha).
2. Ash coloured hair ( Shyava Varna ).
3. Hair resembling like water (Jala prabham).
4. Yellowish hair (Peetabham).
5. Burning sensation in the scalp.
6. White hair (Shukla Varna).
7.3 Criteria for assessment of result:-
Subjective and objective parameter will be assessed for the result.
A Subjective parameter:-
1. Akala Kesha Vaivarnyata.
2. Hair texture.
B. Objective parameter:-
1. Random hair count.
2. Photography presentation.
7.4 Laboratory investigation: -
1. Blood Routine.
7.5 The ethical clearance has been obtained from your institution – Yes.
8. LIST OF REFERENCES:
1. Tripati B, Astanga Hrudaya with Nirmala Hindi commentary,ed. Varanasi. Choukambha Sanskrit Pratisthtan;1999.p.1054.
2. Sharma SP. Astanga Samgraha of vrddha vagbhata with sasilekha commentary of Indu, Reprinted ed.Varanasi(india): chawkambha sanskrit series office; 2008 p.511.
3. Vidyasagar PS. sarangadhara samhita Poorvakhanda with dipika commentary of Adhamalla and Gudharatha dipika commentary of Kasirama, 6th ed, Choukambha Orientalia Varanasi;2011, p.116.
4. Agnivesha,Charaka, Drudabala,Chakrapanidatta.Charaka samhita.Reprint edi.Varanasi:Chaukhamba Orientalia;2011.p344.
5. Gupta KU,Vaidyaka Shabda Sindhuh.4thed,Varanasi.Chaukhamba Orientlaia;1999,p.647.
6. Willium MW, A Sanskrit English Dictionary.ed.Delhi:Bharatiya Granta Niketan;1851,p.618.
7. Gupta KU, Vaidyaka Shabda Sindhuh.4thed,Varanasi.Chaukhamba Orientalia;1999,p.2.
8. http:/
9. http:/
10. McDonough PH, Schwartz RA. Premature hair graying.Newark(USA). Dermatology and Pediatrics, New Jersey Medical School, 2012 Apr; 89(4):161-5.
11. Seong Jin Jo, Seung Hwan Paik.Hair Graying Pattern Depends on Gender, Onset-Age and Smoking Habits. Acta Derm Venereol; 2012 Mar;92(2):160-1.
12. Pandey G,Basavarajeeyam.ed Varanasi: Chaukamba Krishnadas;2010.p.717-718.
13. Acharya YT. Charaka Samhita with Ayurveda Deepika commentary of Chakrapanidatta. Reprnt. Varanasi : Chaukambha orientalia;2011.p.145.
14. Acharya JT,Sushruta Samhita with Nibandha sangraha commentary of Dalhana and Nayachandirka panjika commentary of Gayadas on Nidana sthana, 7th ed. Varanasi.Choukambha Orientalia;2002. p.332.
15. Upaddhaya Y and Shastri S , Madhav Nidana Uttararda with madhukosa commentary by Shri Vijaya raksita & Srikanthadatta, 20th ed, Choukambha Sanskrit sansthan Varanasi ;1993, p.205.
16. Mishra BS , Bhavaprakasha with vidoyotini hindi commentary part 2, 11th ed Varanasi, Choukambha Sanskrit sansthan; 2004. p.594.
17. Shastri BS, Yogaratnakara,Reprnt ed.Varnasi:Chaukamba Prakashan;2010.p.273.
18. Vangasena,Vangasena Samhita english translation by Saxena N.Edi.Varanasi:Chaukhamba Sanskrit Series;Vol II.2004.p.817.
19. Dingari L,The Shalakya Tantra,Delhi.Chaukamba Sanskrit Pratishtan;2005.p.31
20.Mishra D,Kaumarbrtya.Rprnt,Delhi.Chaukhamba Sanskri Pratistan;2007.p.12.
21. Srikantamurth,.Astanga Hrudaya vol II.ed Varanasi: Krishnadas Academy;1992.p.589.
22. Mishra SN,Baishajya Ratnavali of Govinda Das Sen.ed. Varnasi,Chaukambha Surabharati Prakashan;2012.p.16.
8. Signature of the Candidate :
- Remarks of Guide:
11. Name and Designation of :
(In block letters)
11.1 Guide :Dr Abhijit HN
Asst. Professor,
Deptt. Of Shalakya Tantra
S.D.M.College of Ayurveda and Hospital,
Hassan
11.2 Signature:
11.3 Head of the Department :Dr. Ashwini M. J.
Asst. Professor, and H.O.D
Deptt. Of Shalakya Tantra
S .D.M. College of Ayurveda & Hospital
Hassan, Karnataka.
11.4 Signature:
12.1 Remarks of the
Chairman and Principal:
12.2 Principal:Dr. Prasanna N. Rao M.S. (Ayu.) Ph.D.
S.D.M. College of Ayurveda & Hospital
Hassan, Karnataka.
12.3 Signature :