CHINESE MEDICINAL BIOTECHNOLOGY

Bimonthly Established in December 2006 Volume 4, Number 2 April 10, 2009

Responsible Institution

Ministry of Health of the People’s Republic of China

Sponsor

China Medicinal BiotechAssociation

7B Zaojunmiao Road, Haidian District, Beijing 100081, China

Editing

Editorial Board of Chinese Medicinal Biotechnology

Tel: 0086-10-62135779

Fax: 0086-10-62115976

Email:

Editor-in-Chief

ZHAO Kai(赵铠)

Managing Director

WEN Jian-ping(文建平)

Publishing

China Medicinal Biotech Association

7B Zaojunmiao Road, Haidian District, Beijing 100081, China

Tel: 0086-10-62135779

Fax: 0086-10-62115976

Email:

Printing

Beijing Zhongke Printing Limited Company

Overseas Distributor

China International Book

Trading Corporation

P. O. Box 399, Beijing, China

Code No. BM4275

Mail-Order

Editorial Department of Chinese Medicinal Biotechnology

7B Zaojunmiao Road, Haidian District, Beijing 100081, China

Tel: 0086-10-62135779

Fax: 0086-10-62115976

Email:

CSSN

ISSN 1673-713X

CN 11- 5512 / R

Copyright© 2008 by theChina

Medicinal Biotech Association

All articles published represent the opinions of the authors, not reflecting the official policy of the China Medicinal Biotech Association or the Editorial Board of Chinese Medicinal Biotechnology, unless this is clearly specified.

CONTENTS OF SELECTED ARTICLES

Editorial

Overview of global biopharmaceutical industry………………………………85

HU Xian-wen, CHEN Hui-peng, ZHANG Shu-yong

Original Articles

Study of methylated status of the MGMT gene and its relation

to the alkylating agent drug sensitivity

of glioblastoma cell line SHG-44……………………………………………90

ZHENG Chang-qing, JI Shou-ping, GONG Feng, CHANG Hong-yu, WANG Ying-li,

GAO Hong-wei, LI Su-bo, TAN Ying-xia, ZHANG Yang-pei

Development of a DNA microarray for detection

of mtDNA D-LOOP polymorphism…………………………………………96

HE Qun, LIN Zi-qing, ZHANG Yu-kui, WANG Tian-jiao, PAN Zhong-cheng, ZHAO Yu-jie

Study on prokaryotic expression of Ezrin and its interacting proteins…102

ZHOU Xiao-yan, HAN Jin-xiang, CUI Ya-zhou, ZHANG Song-tao,

ZHONG Ning, SONG Guan-hua

Quality analysis of magnetic resonance fetography with a single-shot

thick-slab turbo spin-echo sequence………………………………………109

LI Chuan, CAI Ping, WANG Xin, LIANG Yong, ZHOU Dai-quan, WANG Jian

Computer navigation aided precision tumor resection

and reconstruction in musculoskeletal tumor surgery……………………114

ZHANG Qing, NIU Xiao-hui, WANG Tao, YU Feng, ZHAO Hai-tao, HAO Lin, DING Yi

Establishment of spectrophotometric method for determining

the concentration of plague vaccine…………………………………………119

WEI Dong, WANG Bing-xiang, LI Ke-mei, PEI Ming-yu, LI Xiao-li, WANG Guo-zhi

125I implantation for unresectable pancreatic carcinoma andempirical

study of normal pancreatic tissue radiation damage……………………123

ZHOU Zheng, DU Yun-feng, LI Tao, REN Li-bin, LU Ke-yu,

SUN Jin-wen, SONG Li-wei, JIA Zhen-geng

Study on dynamic characteristics of Uricase from pig……………………128

KOU Wen-e, RONG Jun, YU Qin

Reviews

Research advances in immunology of hepatitis C virus

hypervariable region 1…………………………………………………………134

AN Yuan, XIU Bing-shui, ZHANG Jin-gang, QIU Yan

Category and application of antibacterial microorganisms

and antagonistic metabolites…………………………………………………137

WAN Xue-qin, LI Wan-ke-lan, CUI Zhi-xin, DUAN Sui-fang, TANG Dong-sheng

Anti-CD20 antibody therapy for non-Hodgkin’s lymphoma………………140

ZHANG Guan-yi, ZHANG Jiu-ding, CHEN Hui-peng, HU Xian-wen

Research advances in category and chemical structure

of red tide algal toxins…………………………………………………………144

LIU Jun-xiu, HE Pei-min

Research advances in bioactivities of hyaluronic acid……………………148

KE Chun-lin, ZENG Xiao-xiong

Research advances in mechanisms of buccal absorption enhancer……… 152

LIU Fei, GAO Yong-liang