Chemistry 226 - Organic Chemistry Laboratory I

Fall 2008

Instructor: Dr. Jeremy WesselOffice: Pel 245C

Office Phone: (985) 448-4504E-mail:

Office Hours: 9:40-11:40 MF, 9:40-10:40 W, 9:00-12:00 T, 10:00-12:00 R, 1:00-3:00 F

Catalog Description:Chemistry 226. Organic ChemistryLaboratoryI. 2-0-6. Prerequisite: CHEM 110. Prerequisite or corequisite: CHEM 222. An introduction to the study of the properties and preparation of organic compounds. (40.0504)

Prerequisite: CHEM 110Prerequisite or corequisite: CHEM 222

Required Texts and Other Materials:

1 – Lab Manual, Chemical Education Resources

2 - Safety goggles

3 - Laboratory notebook. Bound, duplicating with tear out sheets

Required Supplemental Readings: None

Course Goals: The student will develop an understanding of and employ proper techniques used in organic synthesis, data collection, product analysis, and documentation.

Student Outcome Objectives:

At the end of this course the student will be able to

  • Separate different compounds based on solubility,
  • Extract products from various solvents,
  • Recrystallize products,
  • Perform fractional and simple distillation,
  • Synthesize various organic compounds,
  • Analyze and identify organic compounds by infrared spectroscopy, thin-layer chromatography, gas chromatography, and nuclear magnet resonance.

Course Content:(see schedule for order)

  • Melting Points
  • Recrystallization
  • Distillation
  • Extraction
  • Thin-Layer Chromatography
  • Gas Chromatography
  • Infrared Spectroscopy
  • NMR Spectroscopy
  • Isolating Caffeine from Tea
  • Dehydration
  • Esterification
  • Nucleophilic Substitution
  • Electrophilic Aromatic Substitution
  • Reduction
  • Synthesis of Phenacetin
  • The Aldol Condensation

Course Requirements:

All students will perform experiments using proper safety practices.

Notebook: 25 points/experiment12 experiments300 points

Formal reports onextraction, reduction (50 pts. each)100 pts

Midterm Exam100 points

Final Exam 100 points

600 points

Method of Evaluation: Grades will be determined using the following scale:

A: 90-100B: 80-90C: 70-80D: 60-70F: <60

Honors students may obtain honors credit by completing a special project determined with the instructor.

Make-up Policy: Missed labs can be made up for an excused absence. Make-ups must be completed within two weeks of the experiment date.

Attendance Policy: Attendance is mandatory.

Academic Honesty Policy: Anyone found cheating will be subject to the penalties stated in Student Code of Conduct including but not limited to a score of zero on exam, expulsion from the class or expulsion from the University.

Semester Withdrawals: The last day to withdraw from the class with a ‘W’ is October 24, 2008.

Academic Disabilities Policy: If you have a documented disability that requires assistance, you will need to register with the Office of Disability Services for coordination of your academic accommodations. The Office of Disability Services is located in Peltier Hall, Room 100-A. The phone number is (985) 448-4430 (TDD 449-7002).

Class Disruptions: The use of cellular phones, pagers or any other electronic personal device is prohibited in class. Any infractions will result in dismissal from class and 0 for the experiment.

Academic Grievances:

The proper procedure for filing grade appeals or grievances related to academic matters is listed in Section 5 of the Code of Student Conduct and at the following link:

Continued Learning following an Extreme Emergency:

In order to make continued learning possible following an extreme emergency, students are responsible for:

•reading regular emergency notifications on the NSU website;

•knowing how to use and access Blackboard (or university designated electronic delivery system);

•being familiar with emergency guidelines;

•evacuating textbooks and other course materials;

•knowing their Blackboard (or designated system) student login and password;

•contacting faculty regarding their intentions for completing the course.

Faculty are responsible for:

•their development in the use of the Blackboard (or designated) software;

•having a plan for continuing their courses using only Blackboard and email;

•continuing their course in whatever way suits the completion of the course best, and being creative in the continuation of these courses;

•making adjustments or compensations to a student’s progress in special programs with labs, clinical sequences or the like only in the immediate semester following the emergency.

Schedule of Experiments

Day / Experiment / Day / Experiment
18August / Check In/Safety / 20August / TECH 701 Melting Points
25August / TECH 703 Recrystallization / 27August / TECH 704 Distillation
1September / Labor DayHoliday / 3 September / TECH 704 Distillation
8September / TECH 705 Extraction / 10September / TECH 705 Extraction
15September / TECH 707/TECH 709 TLC/GC / 17September / TECH 710/TECH 711 IR/NMR
22September / Review / 24September / Midterm
29September / SYNT 732 Isolating Caffeine / 1October / REAC 712 Dehydration
6October / REAC 714 Sn1 & Sn2 Reactions / 8October / REAC 714 Sn1 & Sn2 Reactions
13October / REAC 715 Reduction / 15October / REAC 715 Reduction
20October / REAC 716 Nitration / 22October / REAC 716 Nitration
27October / SYNT 720 Aldol Condensation / 29October / SYNT 720 Aldol Condensation
3November / SYNT 713 Esterification / 5November / SYNT 713 Esterification
10November / SYNT 726 Phenacetin / 12November / SYNT 726 Phenacetin
17November / Review/Check Out / 19November / Lab Final