Ch 1 Principles of Pharmacy Introduction to Pharmacy

Ch 1 Principles of Pharmacy Introduction to Pharmacy

Hippocratic oath started with ancient greeks still used used today. One major pledge is

*

Created in the First century A.D. this standard text on drugs was used 15 centuries

• *

Ch 2 Pharmacy Laws

1st US laws in pharmacy is *

-make sure drug is no harmful and no false labeling

Food, Drug, and Cosmetic Act of 1938 later created the *

NDA abbreviation is *

so before marketing manufacturers needed to submit

FDC act only required drugs to be safe for consumption not that they be effective or useful

Durham-Humphrey Amendment of 1951

-*

Kefauver-Harris Amendment of 1962

-drug not only be safe but also effective

-created *

-takes avg. 7 years before reaching marketplace to proof safe and effective

Compensate for research costs government allowed

* to protect brand names of drugs

What created controlled substance drugs?

*

National drug code has 10 characters that identify

-*

* is intended for use in few patients with rare diseases

How many names for one drug

* name like isobutylhydratropic acid

* name like ibuprofen

* name like advil, motrin

Generic drugs are comparable to brand names in dosage, safety, strength, quality, performance, and intended use

some drugs don't have generic

About three-quarters of FDA-approved drugs have generic equivalents. If you can buy a drug in generic form,

Omnibus budget reconciliation act of 1990

pharmacist or tech must offer to counsel patient on drugs

Dietary Supplement Health and Education act 1994

supplements monitor for safety and review false claims

*

-protect confidentiality of patient medical records

-employee continue medical coverage after they leave work

-move health insurance from one employer to another

FDA or Food and Drug administration main job is

*

DEA is under the department of health or justice department?

DEA main duties is to regulate what kind of substances?

*

Is there a federal law what regulates refilling of prescriptions?

*

remember schedule III, IV, V drug are refillable for up to 6 months

* only has the right to suspend or revoke a license

*is form of negligence in which the standard of care was not met

* ingredient is active ingredient of the drug that exerts therapeutic effect

Vaccine is substance given in order to produce immunity to a disease

Penicillin - is a mold that kills growth of bacteria

* is substance that kills bacteria

Legend drug is *

* drugs - small does stimulate body immune system to target

When a drug is created artificially in a lab is *synthesized drug

* drug is a drug that is created artificially in imitation of naturally occurring substances

A drug is therapeutic if it

maintain health

relieve symptoms

combat illness

try reverse disease process

Drug approval review

1st try to purify compound and study on animal

Clinical studies1st submit INDA (investigational)

gives intent to experiment on human

small group of healthy people then #small with disease then large patient groups

If pass then submit NDA (new drug application) to FDA

cost almost $1 billion for Crestor a new cholesterol drug

Solid dosage form:

Tablets

*most

Capsules

active ingredate in shell

CR abbreviation is for *

CR designed not to release the active drug immediately

Extended release

allow the frequency of dosing reduced & best compliance

Suppositories are given *

Inhalation has two forms

Spray * dispersion of material

aerosol that is *

MDI abbreviation *

administration

1. Shake well

2.Prime canister

3.spacer when inserting drug

4.breath out then make a seal

5. Acitvate taking a deep breath

6. Hold the breath and slowly exhale

IV abbreviated intravenous infusion

IM abbre for *

Syringe is device to draw up and deliver medication through a needle